The mental health of frontline and non-frontline medical workers during the coronavirus disease 2019 (COVID-19) outbreak in China: A case-control study.

Abstract:

BACKGROUND AND OBJECTIVE:Coronavirus disease 2019 (COVID-19) is a new infectious disease with high transmissibility and morbidity. It has caused substantial mental distress to medical professionals. We aimed to compare the psychological impact of the COVID-19 outbreak between frontline and non-frontline medical workers in China. METHODS:This case-control study recruited 1173 frontline and 1173 age- and sex-matched non-frontline medical workers during the COVID-19 outbreak (February 11 to 26, 2020). A set of online questionnaires were used to measure mental problems (i.e., anxiety, insomnia, and depressive symptoms), and help-seeking behavior and treatment for these mental problems. RESULTS:Frontline medical workers had higher rates of any mental problem (52.6% vs. 34.0%, adjusted OR=1.88, 95% CI=1.57-2.25), anxiety symptoms (15.7% vs. 7.4%, adjusted OR=1.95, 95% CI=1.46-2.61), depressed mood (marginally insignificant; 14.3% vs. 10.1%, adjusted OR=1.32, 95% CI=0.99-1.76) and insomnia (47.8% vs. 29.1%, adjusted OR=1.96, 95% CI=1.63-2.36) than non-frontline medical workers. No significant difference was observed in terms of suicidal ideation (12.0% vs. 9.0%, adjusted OR=1.25, 95% CI=0.92-1.71), help-seeking (4.5% vs. 4.5%, adjusted OR=1.00, 95% CI=0.53-1.87) or treatment (3.4% vs. 2.3%, adjusted OR=1.38, 95% CI=0.54-3.52) for mental problems. LIMITATIONS:The case-control nature of the data precludes causal inferences, and there is a possibility of bias related to self-reports. CONCLUSIONS:Frontline medical workers had more mental problems but comparable help-seeking behaviors and treatment for these problems than non-frontline medical workers. These findings highlight the timely mental support and intervention for medical workers, especially for those on the frontline.

journal_name

J Affect Disord

authors

Cai Q,Feng H,Huang J,Wang M,Wang Q,Lu X,Xie Y,Wang X,Liu Z,Hou B,Ouyang K,Pan J,Li Q,Fu B,Deng Y,Liu Y

doi

10.1016/j.jad.2020.06.031

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

210-215

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(20)32389-2

journal_volume

275

pub_type

杂志文章
  • Does a history of substance abuse and illness chronicity predict increased impulsivity in bipolar disorder?

    abstract:BACKGROUND:Impulsivity is a common feature shared by bipolar disorder (BD) and substance use disorder (SUD). SUD and recurrent mood episodes are considered to be risk factors for poor outcome in BD. However, the association between impulsivity, illness chronicity and SUD in BD remains unexplored. METHODS:103 BD patien...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.03.010

    authors: Bauer IE,Meyer TD,Sanches M,Zunta-Soares G,Soares JC

    更新日期:2015-07-01 00:00:00

  • A prospective investigation of the relationships among sleep quality, physical symptoms, and depressive symptoms during pregnancy.

    abstract::The aim of this study was to examine the prospective relationship between pregnancy physical discomforts experienced during the second trimester and late pregnancy depressive symptoms, as well as the mediating effect of sleep quality on antenatal depressive symptomatology. Healthy pregnant women (N=257) completed the ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2009.09.015

    authors: Kamysheva E,Skouteris H,Wertheim EH,Paxton SJ,Milgrom J

    更新日期:2010-06-01 00:00:00

  • CACNB2 rs11013860 polymorphism correlates of prefrontal cortex thickness in bipolar patients with first-episode mania.

    abstract:BACKGROUND:The β2 subunit of the voltage-gated l-type calcium channel gene(CACNB2) rs11013860 polymorphism is a putative genetic susceptibility marker for bipolar disorder (BD). However, the neural effects of CACNB2 rs11013860 in BD are largely unknown. METHODS:Forty-six bipolar patients with first-episode mania and e...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.02.007

    authors: Chen J,Tan J,Greenshaw AJ,Sawalha J,Liu Y,Zhang X,Zou W,Cheng X,Deng W,Zhang Y,Cui L,Liu C,Sun J,Cheng X,Wu Q,Li S,Mai S,Lan X,Chen Y,Cai Y,Zheng C,Cheng D,Zhang B,Yang C,Li X,Li X,Ye B,Yousefnezhad

    更新日期:2020-05-01 00:00:00

  • Onset of Depression Inventory (ODI)--assessment of the speed of onset of depressive episodes.

    abstract:BACKGROUND:The development of a full blown depressive episode may be very rapid, taking less than one hour, or be very slow, taking up to months. In a previous study with outpatients it was found that the majority (58%) of depressive episodes within bipolar affective disorders (BD) develop within one week whereas this ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2012.05.002

    authors: Strauss M,Sander C,Mergl R,Merz C,Schönknecht P,Hegerl U

    更新日期:2012-12-15 00:00:00

  • Pilot randomized controlled trial of a Spanish-language Behavioral Activation mobile app (¡Aptívate!) for the treatment of depressive symptoms among united states Latinx adults with limited English proficiency.

    abstract:BACKGROUND:To address the need for disseminable, evidence-based depression treatment options for Latinx adults with limited English proficiency (LEP), our team developed ¡Aptívate!, a Spanish-language Behavioral Activation self-help mobile application. Primary aims of this study were to: 1) examine feasibility and upta...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jad.2019.03.009

    authors: Dahne J,Collado A,Lejuez CW,Risco CM,Diaz VA,Coles L,Kustanowitz J,Zvolensky MJ,Carpenter MJ

    更新日期:2019-05-01 00:00:00

  • Risk factors for recurrence in depression in the Lundby population, 1947-1997.

    abstract:BACKGROUND:Depression is a common disorder in both men and women, and the recurrence rate is high. The aim of this study was to identify risk factors for recurrence in depression in the Lundby Study. METHODS:The Lundby Study is a community-based longitudinal study with focus on mental health. The study started in 1947...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2017.11.038

    authors: Nöbbelin L,Bogren M,Mattisson C,Brådvik L

    更新日期:2018-03-01 00:00:00

  • Diurnal variation: reliability of measurement and relationship to typical and atypical symptoms of depression.

    abstract::We used three rating scales to study diurnal variation of mood in 37 patients with major depressive disorder (17 drug-free patients and 20 treatment refractory patients on stable regimens of antidepressant medication). The three rating scales included global self-ratings administered twice a day; an itemized, prospect...

    journal_title:Journal of affective disorders

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0165-0327(92)90016-y

    authors: Leibenluft E,Noonan BM,Wehr TA

    更新日期:1992-11-01 00:00:00

  • Meta-analytic review of the effects of a single dose of intranasal oxytocin on threat processing in humans.

    abstract:BACKGROUND:Heightened threat sensitivity is a transdiagnostic feature in several psychiatric disorders. The neuropeptide oxytocin has been shown to reduce fear related behaviours and facilitated fear extinction in animals. These findings have led to increasing interest to explore the effects of intranasal oxytocin on t...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jad.2017.08.041

    authors: Leppanen J,Ng KW,Kim YR,Tchanturia K,Treasure J

    更新日期:2018-01-01 00:00:00

  • Cortical inhibitory and excitatory correlates of depression severity in children and adolescents.

    abstract:OBJECTIVES:Neurophysiologic correlates of depression severity potentially have great utility in diagnosis and treatment planning. Transcranial magnetic stimulation (TMS) measures of cortical inhibition and excitability have shown promise as biomarkers in psychiatry, but no prior work has examined correlates of illness ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.10.020

    authors: Lewis CP,Nakonezny PA,Ameis SH,Vande Voort JL,Husain MM,Emslie GJ,Daskalakis ZJ,Croarkin PE

    更新日期:2016-01-15 00:00:00

  • Prevalence and determinants of antenatal depression among pregnant women in a predominantly rural population in Ghana: the DON population-based study.

    abstract:BACKGROUND:While depression during pregnancy is one of the strongest risk factors for postnatal depression, it has been comparatively little studied, particularly in sub-Saharan Africa. METHODS:Cohort study nested within 4-weekly surveillance of all women of reproductive age to identify pregnancies and collect data on...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.04.009

    authors: Weobong B,Soremekun S,Ten Asbroek AH,Amenga-Etego S,Danso S,Owusu-Agyei S,Prince M,Kirkwood BR

    更新日期:2014-08-01 00:00:00

  • Household food insecurity is associated with depressive symptoms in the Canadian adult population.

    abstract:BACKGROUND:It is essential to identify factors associated with depression as it is a highly prevalent and disabling mental disorder. The aim of this study was to examine the association between depressive symptoms and household food security status among the Canadian adult population. METHODS:This is a cross-sectional...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.10.057

    authors: Shafiee M,Vatanparast H,Janzen B,Serahati S,Keshavarz P,Jandaghi P,Pahwa P

    更新日期:2021-01-15 00:00:00

  • Characteristics of interpretation bias and relationship with suicidality in a psychiatric hospital sample.

    abstract:BACKGROUND:Interpretation bias, the tendency to interpret ambiguous situations negatively (or to lack a positive bias), is a cognitive vulnerability associated with psychopathology. However, there is a lack of research characterizing this bias in psychiatric samples, including whether it is also a risk factor for suici...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2016.09.021

    authors: Beard C,Rifkin LS,Björgvinsson T

    更新日期:2017-01-01 00:00:00

  • Feeling down? A systematic review of the gut microbiota in anxiety/depression and irritable bowel syndrome.

    abstract::Background Anxiety/depression and irritable bowel syndrome (IBS) are highly prevalent and burdensome conditions, whose co-occurrence is estimated between 44 and 84%. Shared gut microbiota alterations have been identified in these separate disorders relative to controls; however, studies have not adequately considered ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,评审

    doi:10.1016/j.jad.2020.01.124

    authors: Simpson CA,Mu A,Haslam N,Schwartz OS,Simmons JG

    更新日期:2020-04-01 00:00:00

  • Predictors of acute stress disorder severity.

    abstract:BACKGROUND:The DSM-IV diagnosis of acute stress disorder (ASD) describes a posttraumatic reaction that occurs two to twenty-eight days following a trauma and involves symptoms of intrusion, avoidance, hyper-arousal and dissociation. A better understanding of ASD and its pathogenesis could lead to improved post-trauma h...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2013.01.041

    authors: Suliman S,Troeman Z,Stein DJ,Seedat S

    更新日期:2013-07-01 00:00:00

  • Effect of depressive symptoms on the evolution of neuropsychological functions over the course of adolescence.

    abstract:INTRODUCTION:Comprehensive understanding of the association between depression and neuropsychological functioning over the course of adolescence requires developmentally sensitive assessment through longitudinal data. The aim of current study is to examine the concurrent and subsequent effects of depressive symptoms on...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2017.11.060

    authors: Afzali MH,Oleary-Barrett M,Séguin JR,Conrod P

    更新日期:2018-03-15 00:00:00

  • Interventions that are helpful for depression and anxiety in young people: a comparison of clinicians' beliefs with those of youth and their parents.

    abstract:BACKGROUND:The aim of the research was to assess the consensus of clinicians about the appropriate treatments for depression and anxiety in youth, to discover any major differences between clinicians' beliefs and those of young people and their parents, and to assess whether clinicians' beliefs were consistent with cli...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2008.02.021

    authors: Jorm AF,Morgan AJ,Wright A

    更新日期:2008-12-01 00:00:00

  • Antenatal depression and anxiety across pregnancy in urban South Africa.

    abstract:BACKGROUND:Depression and anxiety in pregnancy have negative consequences for women and their offspring. High adversity places pregnant women at increased mental health risk, yet there is a dearth of longitudinal research in these settings. Little is known about the pathways by which these problems emerge or persist in...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.08.010

    authors: Redinger S,Pearson RM,Houle B,Norris SA,Rochat TJ

    更新日期:2020-12-01 00:00:00

  • The sick role, illness cognitions and outcomes in bipolar disorder.

    abstract:OBJECTIVE:In some individuals, recovery from episodes of mental illness may be impeded by maladaptive illness beliefs and behaviors. For individuals with chronic illness, acceptance of its presence and consequences is necessary to seek appropriate treatment, adjust their lifestyle, and adhere to recommended management ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2012.07.003

    authors: Berk M,Berk L,Dodd S,Fitzgerald PB,de Castella AR,Filia S,Filia K,Brnabic AJ,Kelin K,Montgomery W,Kulkarni J,Stafford L

    更新日期:2013-03-20 00:00:00

  • Mental disorders in Spanish university students: Prevalence, age-of-onset, severe role impairment and mental health treatment.

    abstract:BACKGROUND:The university period carries risk for onset of common mental disorders. Epidemiological knowledge on mental disorders among Spanish university students is limited. AIMS:To estimate lifetime and 12-month prevalence, persistence and age-of-onset of mental disorders among Spanish first-year university student...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.04.050

    authors: Ballester L,Alayo I,Vilagut G,Almenara J,Cebrià AI,Echeburúa E,Gabilondo A,Gili M,Lagares C,Piqueras JA,Roca M,Soto-Sanz V,Blasco MJ,Castellví P,Mortier P,Bruffaerts R,Auerbach RP,Nock MK,Kessler RC,Jordi A,UNIVER

    更新日期:2020-08-01 00:00:00

  • Mitochondrial inheritance in depression, dysmotility and migraine?

    abstract:BACKGROUND:Several studies have reported a high degree of association of the common conditions of depression, bowel dysmotility and migraine. Mitochondrial dysfunction and mitochondrial DNA (mtDNA) sequence variants have been linked individually to each of these three conditions, providing a plausible hypothesis for th...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2005.05.009

    authors: Burnett BB,Gardner A,Boles RG

    更新日期:2005-09-01 00:00:00

  • Plasma catecholamine metabolites in antidepressant-exacerbated mania and psychosis.

    abstract::We measured plasma free HVA and MHPG in 39 cases of psychosis or mania judged to be caused by antidepressant exacerbation of symptoms. A total of 24 of patients had been receiving selective serotonin reuptake inhibitors (SSRI's). The SSRI group showed a pattern of increased plasma HVA similar to a comparison group of ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(00)00327-x

    authors: Fortunati F,Mazure C,Preda A,Wahl R,Bowers M Jr

    更新日期:2002-04-01 00:00:00

  • Neuroendocrine studies in affective disorders. Part 1. Plasma prolactin response to thyrotropin-releasing hormone in affective disorders: effect of ECT.

    abstract::The plasma prolactin response to thyrotropin-releasing hormone, which is thought to be mediated by central 5-HT mechanisms, has been studied in patients with affective disorders. There was no difference between depressive patients (taken as a whole), bipolar patients undergoing a manic phase and controls in the prolac...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(80)90032-4

    authors: Coppen A,Rao VA,Bishop M,Abou-Saleh MT,Wood K

    更新日期:1980-12-01 00:00:00

  • A meta-analysis of temperament and character dimensions in patients with mood disorders: Comparison to healthy controls and unaffected siblings.

    abstract:BACKGROUND:Cloninger's psychobiological model of personality has been extensively applied to subjects affected by mood disorders (MOOD). However, most studies are widely heterogeneous in terms of sample size, methods of assessment, and selection of participants. METHODS:We conducted a systematic review of literature a...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jad.2015.12.077

    authors: Zaninotto L,Solmi M,Toffanin T,Veronese N,Cloninger CR,Correll CU

    更新日期:2016-04-01 00:00:00

  • Rorschach markers in offspring of manic-depressive patients.

    abstract:BACKGROUND:Previously published data show large differences between euthymic Israeli adult bipolar patients and US normative data on several measures of psychological functioning as assessed with a sensitive projective measure (Rorschach Inkblot Test). The current study examines the Rorschach performance of healthy off...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(99)00148-2

    authors: Osher Y,Mandel B,Shapiro E,Belmaker RH

    更新日期:2000-09-01 00:00:00

  • Buspirone augmentation of selective serotonin reuptake inhibitors (SSRIs) in social phobia.

    abstract::We evaluated the efficacy of buspirone, in the augmentation of social phobic symptom response to the selective serotonin reuptake inhibitors (SSRIs). Ten patients meeting DSM-III-R criteria for generalized social phobia were studied. Patients obtaining only a partial response to an adequate trial of an SSRI, received ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(96)00030-4

    authors: Van Ameringen M,Mancini C,Wilson C

    更新日期:1996-07-08 00:00:00

  • Prefrontal activation during a working memory task differs between patients with unipolar and bipolar depression: A preliminary exploratory study.

    abstract:BACKGROUND:To identify bipolar disorder during the initial stages of a depressive episode has always been a great clinical challenge. Patterns of functional brain activity may underlie the differences in the neural mechanisms of bipolar depression (BD) and unipolar depression (UD). This study aimed to investigate the d...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2017.07.031

    authors: Zhu Y,Quan W,Wang H,Ma Y,Yan J,Zhang H,Dong W,Yu X

    更新日期:2018-01-01 00:00:00

  • Repetitive transcranial magnetic stimulation for the treatment of postpartum depression.

    abstract:BACKGROUND:Postpartum depression (PPD) is a common and gravely disabling health concern. Repetitive transcranial magnetic stimulation (rTMS) is an FDA approved treatment for major depression and may be a valuable tool in the treatment of PPD. The treatment effect of rTMS is rapid, generally well tolerated, without syst...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.11.069

    authors: Cox EQ,Killenberg S,Frische R,McClure R,Hill M,Jenson J,Pearson B,Meltzer-Brody SE

    更新日期:2020-03-01 00:00:00

  • Anti-anxiety drugs reduce conflict-specific "theta"--a possible human anxiety-specific biomarker.

    abstract:BACKGROUND:Syndromes of fear/anxiety are currently ill-defined, with no accepted human biomarkers for anxiety-specific processes. A unique common neural action of different classes of anxiolytic drugs may provide such a biomarker. In rodents, a reduction in low frequency (4-12 Hz; "theta") brain rhythmicity is produced...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jad.2012.11.057

    authors: McNaughton N,Swart C,Neo P,Bates V,Glue P

    更新日期:2013-05-15 00:00:00

  • Bipolar patients treated with long-acting injectable risperidone in Taiwan: A 1-year mirror-image study using a national claims database.

    abstract:OBJECTIVE:Bipolar disorder (BD) is burdensome for patients and healthcare systems. This study evaluated changes in concomitant medication patterns, healthcare utilization, and costs after the initiation of risperidone long-acting injection (RLAI) treatment among BD patients. METHOD:287 BD patients receiving regular RL...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2017.04.074

    authors: Hsieh MH,Chuang PY,Wu CS,Chang CJ,Chung PF,Tang CH

    更新日期:2017-08-15 00:00:00

  • Comparisons of prevalence and related factors of depression in middle-aged adults between urban and rural populations in Japan.

    abstract:BACKGROUND:Findings of urban-rural differences in the prevalence of depression have been controversial, and few reports have directly compared the related factors of depression between urban and rural areas. The present study aimed to investigate differences between urban and rural areas in Japan with regards to the pr...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.11.020

    authors: Fujise N,Abe Y,Fukunaga R,Nakagawa Y,Nishi Y,Koyama A,Ikeda M

    更新日期:2016-01-15 00:00:00