Abstract:
:To compare mortality in bipolar and unipolar manic-depressive patients, 2168 manic-depressive first admissions reported to the Danish Psychiatric Central Register were divided into a bipolar group (19%), i.e., patients with at least one admission for mania during an average observation period of six years, and a unipolar group. When compared with the general population, the total group had an increased mortality by suicide and accidents in both sexes and by non-violent causes in men. The bipolar group had a higher non-violent mortality than the unipolar group, but the violent mortality was not different. Statistical problems introduced by patients switching from the unipolar to the bipolar group during the period of observation are discussed.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Weeke A,Vaeth Mdoi
10.1016/0165-0327(86)90074-1subject
Has Abstractpub_date
1986-11-01 00:00:00pages
227-34issue
3eissn
0165-0327issn
1573-2517pii
0165-0327(86)90074-1journal_volume
11pub_type
杂志文章abstract:INTRODUCTION:Recent studies have demonstrated that cortical brain areas tend to oscillate at a specific natural frequency when directly perturbed by transcranial magnetic stimulation (TMS). Fast electroencephalographic (EEG) oscillations, which typically originate from frontal regions, have been reported to be markedly...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.05.043
更新日期:2015-09-15 00:00:00
abstract:INTRODUCTION:Fragmented REM sleep may impede overnight resolution of distress and increase depressive symptoms. Furthermore, both fragmented REM and depressive symptoms may share a common genetic factor. We explored the associations between REM sleep fragmentation, depressive symptoms, and a polygenic risk score (PRS) ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.11.077
更新日期:2019-02-15 00:00:00
abstract:BACKGROUND:Many studies have demonstrated that major depression is related to an activation of the inflammatory response system (IRS) with an increased production of proinflammatory cytokines. It has been shown that tricyclic antidepressants and serotonin reuptake inhibitors suppress the activation of the IRS in depres...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00076-2
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Intermediate cognitive phenotypes (ICPs) are measurable and quantifiable states that may be objectively assessed in a standardized method, and can be integrated into association studies, including genetic, biochemical, clinical, and imaging based correlates. The present study used neuropsychological measures...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.08.018
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Studying the phenotypic manifestations of increased genetic liability for Bipolar Disorder (BD) can increase understanding of this disorder. AIMS:We assessed whether genetic risk for BD was associated with childhood psychopathology and features of hypomania in young adulthood within a large population-based...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.12.091
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:This study sought to determine from a recent meta-analysis of pediatric antidepressant trials if a general property of antidepressant medications--the multiple-dosing medication half-life--is associated with risks for suicidal ideation or behavior. METHODS:Relative risks for suicidal behavior (ideation, att...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析
doi:10.1016/j.jad.2008.06.018
更新日期:2009-04-01 00:00:00
abstract::This is the first of three articles dealing with some basic aspects of the relationship between life events and depression, and is also one part of a larger study in which the possible impact of stressful events has been studied from a multifactorial point of view. Two-hundred and four patients suffering from a depres...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(84)90060-0
更新日期:1984-08-01 00:00:00
abstract:BACKGROUND:Depression is the most prevalent psychiatric disorder in the elderly and several studies indicate that 10-15% of persons over 65 years suffer from significant depressive symptoms. Despite the high prevalence, most cases of depression in the elderly remain unrecognized and untreated, maybe because of a differ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00245-7
更新日期:2001-05-01 00:00:00
abstract::To investigate the interrelationships between the noradrenergic and serotonergic systems and the hypothalamic-pituitary-adrenal (HPA) axis, we measured the excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) and free cortisol (UFC) in 24-h urine both before and after loading with 2 g L-tryptophan (L-TRP) orally in 24 ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(89)90040-2
更新日期:1989-09-01 00:00:00
abstract:BACKGROUND:Findings from three decades of epidemiological studies suggest that media diffusion of stories about suicide is related to increases in suicidal behaviours in the population exposed to the media reports. However, we still know little about the psychological processes and personal vulnerabilities that prompt ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.04.050
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Research suggests that screening for suicidality does not have iatrogenic effects; however, less is known regarding the impact of repeatedly screening for suicidal ideation among individuals with varying levels of exposure to these screenings. This staggered sequential study evaluated whether suicidal ideati...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.02.022
更新日期:2018-05-01 00:00:00
abstract::There are an increasing number of pharmacologic therapies for bipolar disorder. Two of these agents, the anticonvulsants carbamazepine (CBZ) and valproate (VPA), were first developed over 30 years ago for the treatment of epilepsy, and subsequent studies demonstrated that they are also effective in the treatment of ac...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2006.04.030
更新日期:2006-10-01 00:00:00
abstract:INTRODUCTION:Many studies of patients with major depression have reported that a significant decrease in serum free T(4) index is associated with specific treatments; what has been unanswered is whether these observations are generalizable. This study evaluated baseline thyroid function and its relationship to rapidity...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2006.10.012
更新日期:2007-06-01 00:00:00
abstract::One explanation for the association between mitral valve prolapse (MVP) and panic attacks in clinic populations is that panic attacks represent a set of symptoms caused by mitral prolapse. Since mitral prolapse is often familial, this hypothesis predicts a higher incidence of panic attacks in relatives of persons with...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(82)90042-8
更新日期:1982-06-01 00:00:00
abstract:BACKGROUND:Brain-derived neurotrophic factor (BDNF) has been hypothesized to be involved in the neurobiology of major depression. The aim of this study was to assess the possible relationships between depressive symptoms and serum and/or plasma BDNF levels during 1 year of antidepressant treatment. METHODS:Plasma and ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.05.005
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Recent studies have suggested that eating and sleep problems during early childhood may pose as risk factors for mood and anxiety disorders in later life. We aim to study the associations between early childhood sleep and eating problems, specifically high motor activity during sleep and irregularities in sl...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2006.05.025
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Treatment studies are lacking for patients with bipolar II disorder (BDII). The objective of this study was to compare lamotrigine (LTG) and lithium (Li) monotherapy for the treatment of BDII depression. METHODS:Patients with BDII acute depression were randomized to open-label monotherapy with LTG or Li, an...
journal_title:Journal of affective disorders
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jad.2008.02.004
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Inflammatory responses and inflammatory cytokines have been implicated in the pathogenesis of affective disorders, particularly major depression. Given the limited evidence relating to the potential role of proinflammatory cytokines in generalised anxiety disorder (GAD), we aimed to examine peripheral proinf...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.08.082
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Emotional dysregulation in subjects with attention deficit and hyperactivity disorder (ADHD) is a topic of growing interest among clinicians and researchers. The present study aims at investigating components of emotional dysregulation in adults ADHD compared to subjects suffering from bipolar disorder (BD)....
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2016.03.047
更新日期:2016-07-01 00:00:00
abstract::There is increasing evidence that besides the well-known angiotensin (Ang) II, other renin-angiotensin system (RAS) peptides, including Ang-(1-7), could have important effects at the central level. However, very few things are known about the central actions of Ang-(1-7), while the effects of its administration alone ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.07.024
更新日期:2013-02-20 00:00:00
abstract::The circannual results of the dexamethasone suppression test (DST) were compared in depressed and schizophrenic patients for the periods November-February and March-October. During the winter months, female depressive and schizophrenic patients had lower rates of DST nonsuppression as well as lower concentrations of p...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(92)90022-x
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:There is growing evidence that transcranial direct current stimulation (tDCS) may be an effective treatment for depression. However, no study to date has profiled the antidepressant effects of tDCS using items or factors on depression symptom severity rating scales. This could potentially provide information...
journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2013.02.027
更新日期:2013-08-15 00:00:00
abstract::Assortative mating was determined in 170 spouses of patients with major affective illness (bipolar and unipolar). An increase in affective disorders was found in both wives of affected men and husbands of affected women. The data suggest that assortative mating is present in the familial transmission of affective diso...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(81)90041-0
更新日期:1981-06-01 00:00:00
abstract:BACKGROUND:Transcranial magnetic stimulation (TMS) effectiveness in major depression has so far been studied mainly with high-frequency (>1 Hz) administration (HF-TMS). However, some available studies with low-frequency TMS (LF-TMS) have provided similar response rates to HF-TMS with better tolerance, but the evidence ...
journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2010.10.038
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Whether or not cannabis use may increase the risk for depression and/or anxiety is not clear. For one thing, it has not been possible to draw a definitive conclusion regarding the direction of causality, i.e. whether cannabis use increases the risk for depression/anxiety or vice versa. This study aimed at ex...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.12.045
更新日期:2016-03-15 00:00:00
abstract:OBJECTIVE:This paper examined sex differences in the short-term course of depression and assessed the impact of possibly outcome-affecting factors, including sex-specific recall artefacts and demographic and clinical characteristics. METHODS:A cohort of 179 unipolar depressed inpatients was followed up 1 (T1) and 7 mo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00035-x
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:The stress generation hypothesis posits that individuals with psychopathology engage in maladaptive behaviors that create stress. Although extensively researched in the depression literature, few studies have investigated whether the stress generation hypothesis applies to eating disorders. This study examin...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.11.009
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Dysregulation of HPA axis has been widely described in subjects with bipolar disorder (BD), including changes in cortisol levels during mood episodes and euthymia. However, most of the studies were done with medicated BD patients with variable length of illness, which was shown to interfere on peripheral cor...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.11.046
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:In a previous study examining the association of hyperthymic temperament and daily light exposure (illuminance), we compared hyperthymic scores of the Temperament Evaluation of Memphis, Pisa, Paris and San Diego-auto questionnaire version (TEMPS-A) acquired from residents in Sapporo and Oita in Japan, which ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.03.029
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:The relative importance of individual and country-level factors influencing access to diagnosis and treatment for depression across the world is fairly unknown. METHODS:We analysed cross-national data from the WHO World Health Surveys. Depression diagnosis and access to health care were ascertained using a ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.02.092
更新日期:2018-07-01 00:00:00