Abstract:
BACKGROUND:Although psychological distress is common among patients with chronic diseases, the degree of risk for developing psychological distress is not well-established. Our aim with this study is to determine the odds ratio for psychological distress in patients with cancer as compared to either 1) patients with chronic disease patients without cancer, or 2) healthy controls in a large representative sample of Chinese population. METHODS:Using a multistage, stratified cluster sampling method, 21,101 subjects 18-79 years old were interviewed face-to-face in Jilin province, China. Their psychological status was assessed with the 12-item General Health Questionnaire (GHQ-12). A total score of ≥4 was used as the threshold for determining psychological distress. RESULTS:The prevalence of psychological distress was 14.08% across the entire sample: 10.63% in healthy controls; 14.81% in patients with chronic diseases; and 20% in patients with cancer. Multiple logistic regression analysis indicated that, as compared to the health controls, both cancer (OR = 1.609, 95%CI = 1.245-2.081) and chronic disease patients (OR = 1.330, 95%CI = 1.189-1.478) were more likely to suffer from psychological distress. Moreover, cancer patients had a higher risk of psychological distress than patients with chronic diseases (OR = 1.295, 95%CI = 1.049-1.600; p = 0.016). In addition, the cancer group (2.68 ± 0.114) demonstrated a higher GHQ score than the patients with chronic diseases (2.30 ± 0.017) and healthy controls (1.98 ± 0.029) (both p < 0.001). CONCLUSION:Our results showed both a higher rate and greater degree of psychological distress in patients with cancer. This suggests a need for better psychological management in cancer patients to help alleviate their distress.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Rao WW,Yang MJ,Cao BN,You YY,Zhang YY,Liu YY,Kou C,Yu Y,Cassidy RM,Yu Q,Zhang XYdoi
10.1016/j.jad.2018.11.089subject
Has Abstractpub_date
2019-02-15 00:00:00pages
950-956eissn
0165-0327issn
1573-2517pii
S0165-0327(18)31656-2journal_volume
245pub_type
杂志文章abstract:BACKGROUND:Methylarginines are endogenous nitric oxide synthase inhibitors that have been implicated in depression. This study measured serum concentrations of l-arginine, asymmetric (ADMA) and symmetric (SDMA) dimethylarginine in a representative sample of older community-dwelling adults and determined their associati...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.06.033
更新日期:2013-11-01 00:00:00
abstract::At the present time, there is some concern over the haematological adverse effects of antidepressants. The present paper examines retrospectively 314 clinical trials in depression which were published in English or French between 1958 and 1986 and which used at least one of the following tricyclics: amitriptyline, clo...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
doi:10.1016/0165-0327(89)90037-2
更新日期:1989-09-01 00:00:00
abstract::The comparison of polysomnographic data between a group of nine major depressive adolescents, 12 minor depressive adolescents and 12 controls showed a significant difference in sleep efficiency index and in percentage of awakenings. Sleep efficiency was reduced in major depressive adolescents and the percentage of awa...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(88)90069-9
更新日期:1988-01-01 00:00:00
abstract:INTRODUCTION:Both rumination, a pattern of repetitive, self-focused thought in response to distress, and deficits in executive functions (EFs), a set of cognitive abilities that facilitate higher-order thinking, have transdiagnostic associations with psychopathology. Although empirical studies suggest associations betw...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.06.026
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Depression is a well-recognised problem in the elderly. The aim of this study was to determine the factors associated with predictors of change in depressive symptoms, both in subjects with and without baseline significant depressive symptoms. METHODS:Longitudinal study of community-dwelling elderly people ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.05.007
更新日期:2013-09-25 00:00:00
abstract:BACKGROUND:The maternity blues have been studied world-wide and are generally regarded as a cross-cultural phenomenon. However, low prevalence rates of the blues have been reported recently in studies of Japanese women. The purposes of this study are, firstly, to establish whether the low prevalence noted in Japanese w...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(02)00039-3
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Depression in later life frequently persists and perpetuating factors are of immediate therapeutic relevance to clinicians. No studies of this scale have examined both clinical and neuropsychological predictors of persistent depression in a cross-national European context. METHODS:4095 community dwelling ol...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.10.037
更新日期:2013-05-01 00:00:00
abstract::To investigate the interrelationships between the noradrenergic and serotonergic systems and the hypothalamic-pituitary-adrenal (HPA) axis, we measured the excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) and free cortisol (UFC) in 24-h urine both before and after loading with 2 g L-tryptophan (L-TRP) orally in 24 ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(89)90040-2
更新日期:1989-09-01 00:00:00
abstract:BACKGROUND:Previously published data show large differences between euthymic Israeli adult bipolar patients and US normative data on several measures of psychological functioning as assessed with a sensitive projective measure (Rorschach Inkblot Test). The current study examines the Rorschach performance of healthy off...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00148-2
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the rate of depressive symptomatology and possible underlying factors in adoptive mothers during the transition to motherhood. DESIGN:Cohort survey. SETTING:General Community. PARTICIPANTS:Thirty-nine adoptive mothers of reproductive age registered with international adoption agencies. INTERVE...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2008.09.002
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Accumulating evidence indicates a high prevalence rate of metabolic disturbance in bipolar disorder (BP) patients. However, the prevalence across BP subtypes has been investigated to a lesser degree. In the current study, we surveyed the prevalence of metabolic syndrome among drug-naïve bipolar II patients. ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.08.042
更新日期:2013-03-20 00:00:00
abstract::The advisability of continuing breastfeeding is an important issue for women with postpartum depression or psychosis. A review of the literature on psychotropic drugs in breast milk is presented. All of the major classes of psychotropic drugs (antidepressants, antipsychotics, antianxiety agents, lithium, hypnotics) ha...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/0165-0327(90)90092-m
更新日期:1990-07-01 00:00:00
abstract:OBJECTIVE:Because of the relationship between childhood behavior disorders and adult substance abuse, we hypothesized that substance abusing adult bipolars were more likely to have had behavior disorders as children than nonabusing bipolar adults. METHODS:Conduct disorder (CD) symptoms in 132 bipolar adults were compa...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00176-6
更新日期:1998-03-01 00:00:00
abstract::Oxidative and nitrosative stress (O&NS) could play an important role in the pathophysiology of major depression (MDD). The aim of the present work was to evaluate the specific activity of the main peripheral antioxidant defences (superoxide dismutase--SOD and glutathione peroxidase--GPX) and the level of malondialdehy...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.05.022
更新日期:2012-12-20 00:00:00
abstract:OBJECTIVE:This paper examined sex differences in the short-term course of depression and assessed the impact of possibly outcome-affecting factors, including sex-specific recall artefacts and demographic and clinical characteristics. METHODS:A cohort of 179 unipolar depressed inpatients was followed up 1 (T1) and 7 mo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00035-x
更新日期:1999-12-01 00:00:00
abstract::The authors administered the Illness Attitude Scales, which identify hypochondriacal patients, to 20 nonpsychotic inpatients with DSM-III diagnosis of melancholia before and after 4 weeks of treatment with amitriptyline, and to a matched group of normals. Before treatment characteristic hypochondriacal responses occur...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(86)90045-5
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:CO(2) respiration stimulates both anxiety and dyspnea ("air hunger") and has long been used to study panic vulnerability and respiratory control. High comorbidity with panic attacks suggests individuals with bipolar disorder may also mount a heightened anxiety response to CO(2). Moreover, problems in the aro...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2008.03.020
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:INN 00835 is a synthetic pentapeptide with a potential for rapid onset of action as an antidepressant. Its efficacy was investigated in a pilot study in patients diagnosed with major depression. METHODS:Fifty two patients received either active drug - INN 00835 (26 patients) - or placebo (26 patients), subc...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(99)00187-1
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:In a previous preliminary report, the perception of a decrease in ambient light intensity appeared to be correlated with depression. We prospectively studied this potential link in a controlled study. METHODS:The question, "I've noticed that the lights in my surroundings seem dimmer than usual", was added t...
journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2007.10.021
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Postpartum depression (PPD) negatively impacts maternal health, parenting and development of children. Most previous studies on PPD risk factors are based on Western populations. Additionally, little is known about the association between psychosocial factors during early pregnancy period and PPD. We aimed t...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.03.026
更新日期:2020-05-15 00:00:00
abstract:BACKGROUND:A number of neuropsychological alterations have been found in patients who have attempted suicide. Most studies investigating decision making (DM) abilities in suicide attempters so far have used one single DM task and included patients with a lifetime history of suicide attempts. These studies have yielded ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.10.012
更新日期:2018-01-15 00:00:00
abstract::All maintenance treatment programs are complicated by the issue of patient noncompliance. This report investigates factors contributing to noncompliance during a 2-year study designed to evaluate the efficacy of long-term antidepressant medication in patients with recurrent unipolar depression. Only 21 of 51 patients ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(84)90023-5
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND:The aim was to determine the risk of Mood Disorders (MD), particularly Bipolar Disorders (BD), in Multiple Sclerosis (MS) using standardized psychiatric diagnostic tools. METHODS:Case-control study. CASES:201 consecutive-patients with MS. CONTROLS:804 sex- and age-matched subjects without MS, randomly sel...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.11.008
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:The functional outcome of Bipolar Disorder (BD) is highly variable. This variability has been attributed to multiple demographic, clinical and cognitive factors. The critical next step is to identify combinations of predictors that can be used to specify prognostic subtypes, thus providing a basis for a stag...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.06.005
更新日期:2013-01-10 00:00:00
abstract:BACKGROUND:Postnatal depression can have a major impact on the lives of women affected and on those around them. While effective treatments are available, it would be preferable to prevent the condition. The aim of this review was to examine the effectiveness of antenatal interventions designed to prevent postnatal dep...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2011.02.029
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Schizoaffective disorder is viewed as a heterogeneous diagnosis among psychotic illnesses. Different diagnostic systems differ in their definition with DSM (-IIIR, -IV, and -V) providing a narrower definition than RDC and ICD-10. It is unclear whether this difference is reflected in patient samples diagnosed...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jad.2013.12.001
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Depression presents a significant burden to both patients and society. One treatment that has emerged is vagus nerve stimulation (VNS), an FDA-approved physical treatment for depressive disorders. However, the application of this intervention has been limited by the involvement of surgery and potential side ...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
doi:10.1016/j.jad.2016.02.031
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Increased motor activity is a cardinal feature of the mania of Bipolar Disorder (BD), and is thought to reflect dopaminergic dysregulation. Motor activity in BD has been studied almost exclusively with self-report and observer-rated scales, limiting the ability to objectively quantify this behavior. We used ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.04.018
更新日期:2010-01-01 00:00:00
abstract::The new ICD-10 categories of 'depressive episode' (F32) and 'recurrent depressive disorder' (F33) were evaluated on the levels of diagnoses, subtypes, syndromes and symptoms. Interrater reliability was analyzed from findings of four independent diagnosticians who rated 100 written psychiatric case records with the hel...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(94)90126-0
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:Previous research has suggested that individuals tend to become more religious with age. Research has also shown that as individuals become more religious, they report decreases in depressive symptoms, suggesting that increased levels of religiosity might help to improve one's mental health. The following st...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2018.05.076
更新日期:2018-10-01 00:00:00