Abstract:
:The comparison of polysomnographic data between a group of nine major depressive adolescents, 12 minor depressive adolescents and 12 controls showed a significant difference in sleep efficiency index and in percentage of awakenings. Sleep efficiency was reduced in major depressive adolescents and the percentage of awakenings was increased. Pubertal stage did not appear to have any effect on sleep EEG recordings. The administration of dexamethasone provoked a suppression of cortisol secretion in 50% of major depressive adolescents. Pubertal stage did not appear to have any significant effect on cortisol level after DST.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Appelboom-Fondu J,Kerkhofs M,Mendlewicz Jdoi
10.1016/0165-0327(88)90069-9subject
Has Abstractpub_date
1988-01-01 00:00:00pages
35-40issue
1eissn
0165-0327issn
1573-2517pii
0165-0327(88)90069-9journal_volume
14pub_type
杂志文章abstract:BACKGROUND:Literature suggests that a high proportion of the population with mental disorders remains either untreated or poorly treated. This study aimed to describe the adequacy of treatment for Anxiety and Depressive disorders in Spain, how this differs between providers (primary versus specialised care) and which f...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2006.05.005
更新日期:2006-11-01 00:00:00
abstract::The relationship between ventricular brain ratio (VBR) and clinical variables was investigated in 21 DSM-III depressed patients. None of the following dichotomies--major depression vs. dysthymic disorder, suicidal vs. non-suicidal patients, male vs. female patients--showed any statistically significant differences. An...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(87)90035-8
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:In first-episode psychosis (FEP), symptoms of anxiety and depression are common. We examined whether cognitive performance is associated with these clinical measures in FEP during a one-year follow-up. METHODS:Young adults with non-affective FEP (n = 52) were assessed two months after their first psychiatri...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.11.161
更新日期:2020-02-15 00:00:00
abstract:BACKGROUND:Suicide is a major global mental health problem among college students. The aim of the current study was to explore the association between the psychological strains of the strain theory of suicide and suicidal behaviors among college students. METHODS:Participants comprised 1912 college students (16-28 yea...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.08.042
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:Depression after stroke (DAS) is a serious complication of stroke that significantly restricts rehabilitation. Brain imaging technology is an important method for studying the emotional network of DAS. However, few studies have focused on dynamic interactions within the network. The aim of this study was to i...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.02.020
更新日期:2019-04-15 00:00:00
abstract:BACKGROUND:Over the last decade, suicide rates in the U.S. military have steadily increased, resulting in a call for suicide-related research with military populations. The present project aimed to describe and evaluate the communications (i.e., verbally and in suicide notes) of 13 suicide risk factors in the suicide d...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.05.011
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:The aim of this study was to analyze the impact of pretreatment characteristics and personality disorders on the onset of response in the treatment of panic disorder. METHODS:The data of 73 out-patients with panic disorder who had completed at least 6 weeks of a randomized trial of 24 weeks of either paroxe...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/S0165-0327(03)00043-0
更新日期:2004-05-01 00:00:00
abstract:INTRODUCTION:Many studies of patients with major depression have reported that a significant decrease in serum free T(4) index is associated with specific treatments; what has been unanswered is whether these observations are generalizable. This study evaluated baseline thyroid function and its relationship to rapidity...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2006.10.012
更新日期:2007-06-01 00:00:00
abstract::Sixty-two elderly depressives were located one year after discharge. Eight patients (13%) had died, 2.6 times higher than the expected mortality rate. Patients dying were more likely to have had a diagnosis of cardiovascular disease (P less than 0.001). ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(85)90096-5
更新日期:1985-09-01 00:00:00
abstract::Narrow definitions of schizophrenia increase homogeneity at the expense of leaving unclassified many patients with shizophrenic symptoms. Family history and follow-up studies indicate that many such patients ought to be classified with those having affective disorders. This study determines morbid risks for affective ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(79)90020-x
更新日期:1979-03-01 00:00:00
abstract:BACKGROUND:Albeit obesity and mood disorders frequently co-occur, few studies examined the impacts of this co-occurrence. The aim was to compare individuals with obesity and mood disorders (ObMD) to those with obesity without mood disorder in terms of physical comorbidities, psychological well-being, health behaviours ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.08.065
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Activation syndrome (AS) is a cluster of symptoms listed by the US Food and Drug Administration as possible suicidality precursors during antidepressant treatment. We aimed to clarify whether AS is associated with bipolar II disorder (BP-II) and its related disorder, i.e., bipolar disorder not otherwise spec...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.05.077
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:The development of a full blown depressive episode may be very rapid, taking less than one hour, or be very slow, taking up to months. In a previous study with outpatients it was found that the majority (58%) of depressive episodes within bipolar affective disorders (BD) develop within one week whereas this ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.05.002
更新日期:2012-12-15 00:00:00
abstract:BACKGROUND:Suicidal ideation (SI) is a common and serious clinical concern in people with major depressive disorder (MDD). Inconsistent evidence suggests that individuals with SI may have a lower measured intelligence quotient (IQ) than those without SI. The aims of this study were to examine SI prevalence and its asso...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.12.017
更新日期:2019-04-01 00:00:00
abstract::There are an increasing number of pharmacologic therapies for bipolar disorder. Two of these agents, the anticonvulsants carbamazepine (CBZ) and valproate (VPA), were first developed over 30 years ago for the treatment of epilepsy, and subsequent studies demonstrated that they are also effective in the treatment of ac...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2006.04.030
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Previous research identified high/low clusters of prevalence of outpatient-treated depression at municipal level in Catalonia (Spain). This study aims to analyse potential risk factors, both socioeconomic and related to the mental health service planning, which could influence the occurrence of hot/cold spot...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.04.024
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Brain-derived neurotrophic factor (BDNF) has been hypothesized to be involved in the neurobiology of major depression. The aim of this study was to assess the possible relationships between depressive symptoms and serum and/or plasma BDNF levels during 1 year of antidepressant treatment. METHODS:Plasma and ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.05.005
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Default mode network (DMN) has been widely reported to be altered in bipolar disorder during major depressive episode (BDD). Recent studies supported the idea that DMN is not an unitary system, but composed of smaller and distinct functional subsystems. The current study aimed to investigate the abnormal fun...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.11.049
更新日期:2021-02-15 00:00:00
abstract:BACKGROUND:Previously published data show large differences between euthymic Israeli adult bipolar patients and US normative data on several measures of psychological functioning as assessed with a sensitive projective measure (Rorschach Inkblot Test). The current study examines the Rorschach performance of healthy off...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00148-2
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Anxiety is a common mental health problem in youth. The current study aimed to test the effectiveness of an online self-directed anxiety prevention program in a school-based sample and to compare two methods of implementing an anxiety program in schools. METHODS:A three-arm cluster stratified randomised con...
journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2016.02.049
更新日期:2016-05-15 00:00:00
abstract:BACKGROUND:Persistent cognitive dysfunction in unipolar depression (UD) contributes to socio-occupational impairment, but there are no feasible methods to screen for and monitor cognitive dysfunction in this patient group. The present study investigated the validity of two new instruments to screen for cognitive dysfun...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.10.059
更新日期:2016-01-15 00:00:00
abstract:BACKGROUND:Insomnia may predict onset of mental disorders in adults. However, it is unclear whether the same directional relationship exists during the peak age range for the onset of major mental disorders and/or whether other types of sleep-wake disturbance, such as hypersomnia, show similar associations. METHODS:Lo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.08.083
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Self-perception of physical health conditions is associated with depression and anxiety. Although some recent studies revealed a high prevalence of depression and anxiety among Bangladeshi university students, no study has yet investigated the link between self-perception of physical health and these common ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.11.153
更新日期:2020-02-15 00:00:00
abstract:BACKGROUND:Postnatal depression can have a major impact on the lives of women affected and on those around them. While effective treatments are available, it would be preferable to prevent the condition. The aim of this review was to examine the effectiveness of antenatal interventions designed to prevent postnatal dep...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2011.02.029
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:The Edinburgh Postnatal Depression Scale (EPDS) was developed as a uni-dimensional measure of depression, however there is evidence that it also measures anxiety. This study examined the factor structure of the EPDS and validity of the identified subscales. METHOD:309 women with infants aged up to 12 months...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.02.004
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Several studies from different epidemiological backgrounds have shown that unipolar depression is more prevalent in females than in males. This study examines gender differences in depression in a sample of 4075 probands recruited representatively from the general population in the northern German epidemiolo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(02)00121-0
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVES:Several studies have recently been conducted that have explored the benefits of psychological interventions in reducing symptomatology or improving outcomes in young people at-risk of developing bipolar disorder. The aim of this review was to explore if such interventions reduce current psychiatric symptoms ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.04.058
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Slower and suboptimal decision making has been identified in adults with schizophrenia and bipolar disorder. Owing to the limited evidence on decision making in first-degree relatives, we aimed to investigate, whether alterations in decision making are present in young children at familial high risk of bipol...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.11.107
更新日期:2021-02-15 00:00:00
abstract:BACKGROUND:Fluctuating hormonal levels observed during the menopausal transition may increase vulnerability to depression in susceptible women. Thus, it is of interest to examine the effect of natural estrogens such as phytoestrogens on the risk of depression in perimenopausal women. METHODS:Our analysis included 193 ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.12.029
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:While major depressive disorder (MDD) is considered to be a heterogeneous disorder, the nature of the heterogeneity remains unclear. Studies have attempted to classify patients with MDD using latent variable techniques, yet the empirical approaches to symptom-based subtyping of MDD have not provided conclusi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.03.053
更新日期:2017-08-01 00:00:00