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Personality disorder and social anxiety predict delayed response in drug and behavioral treatment of panic disorder.

Abstract：

BACKGROUND:The aim of this study was to analyze the impact of pretreatment characteristics and personality disorders on the onset of response in the treatment of panic disorder. METHODS:The data of 73 out-patients with panic disorder who had completed at least 6 weeks of a randomized trial of 24 weeks of either paroxetine only or paroxetine combined with cognitive group-therapy were analyzed in a Cox proportional hazards model. RESULTS:The likelihood of having responded to treatment (defined by a CGI rating of improvement) was more than twice as high for patients without a personality disorder or social phobia than for Patients with a personality disorder or social phobia. CONCLUSIONS:We suggest that patients with these characteristics do benefit from prolonged treatment, and they may profit from an additional treatment focused on social anxiety.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Berger P,Sachs G,Amering M,Holzinger A,Bankier B,Katschnig H

doi

10.1016/S0165-0327(03)00043-0

subject

Has Abstract

pub_date

2004-05-01 00:00:00

pages

75-8

issue

1

eissn

0165-0327

issn

1573-2517

pii

S0165032703000430

journal_volume

80

pub_type

临床试验,杂志文章,随机对照试验

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