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Mauling of the "Celtic Tiger": clinical characteristics and outcome of first-episode depression secondary to the economic recession in Ireland.

Abstract：

BACKGROUND:There is a dearth of studies describing clinical characteristics and outcome of patients who present with mood disorders related to economic recession. AIMS:To describe a cohort of patients admitted with first-episode depression related to the Irish economic recession and compare this cohort with all other first-episode depressives admitted during the same time period (2009-2010). METHODS:A cohort of 137 patients admitted with first-episode depression to an independent university teaching hospital was prospectively identified and followed up from admission over 2 years (mean follow-up 430 days, s.d. 176 days). The cohort was divided into "Celtic Tiger" (patients with first-episode depression secondary to the economic recession) and non-Celtic Tiger control patients (other first-episode depressed patients). Both groups were compared in terms of clinical characteristics at baseline and outcome over follow-up. RESULTS:The number of admissions due to first depressive episodes were higher in recession years 2009/10 than in pre-recession years 2008/9. Celtic Tiger patients were predominantly male and more severely depressed with more marked suicidal ideation (χ(2), p<0.001) than control patients. They were more likely to recover (χ(2), p=0.013), less likely to recur (χ(2), p<0.001) and had faster time to recovery (log rank, p<0.001) and slower time to full recurrence (log rank, p=0.001). The Celtic Tiger patients spent more time asymptomatic and less time at full and subthreshold depression levels over follow-up. LIMITATIONS:Study setting of centre specializing in affective disorders treatment, retrospective nature of follow-up after initial prospective interview and lack of patient follow-up interview. CONCLUSION:The study describes a subgroup of patients with severe depression associated with economic recession with likely high suicide risk but very favourable outcome.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Thekiso TB,Heron EA,Masood B,Murphy M,McLoughlin DM,Kennedy N

doi

10.1016/j.jad.2013.06.024

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

455-460

issue

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(13)00504-1

journal_volume

151

pub_type

杂志文章

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Mauling of the "Celtic Tiger": clinical characteristics and outcome of first-episode depression secondary to the economic recession in Ireland.