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The Diagnostic Melancholia Scale (DMS): dimensions of endogenous and reactive depression with relationship to the Newcastle Scales.

Abstract：

:The two diagnostic Newcastle Scales for depression have been evaluated in a drug trial with antidepressants. By use of latent structure analysis (Rasch models) it was found that two dimensions are necessary for describing the diagnosis of depression, one for endogenous features and one for reactive features. Of the depressed patients 50% had a pure endogenous depression, 14% had a pure reactive depression, 32% had mixed endogenous and reactive depression, and 4% had uncertain diagnosis. In the pure endogenous depression group 77% had a monotonically non-decreasing improvement curve during treatment whereas in the other diagnostic categories around 50% had such an improvement.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Bech P,Allerup P,Gram LF,Kragh-Sørensen P,Rafaelsen OJ,Reisby N,Vestergaard P

doi

10.1016/0165-0327(88)90059-6

subject

Has Abstract

pub_date

1988-03-01 00:00:00

pages

161-70

issue

2

eissn

0165-0327

issn

1573-2517

pii

0165-0327(88)90059-6

journal_volume

14

pub_type

临床试验,杂志文章

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