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Buspirone augmentation of selective serotonin reuptake inhibitors (SSRIs) in social phobia.

Abstract：

:We evaluated the efficacy of buspirone, in the augmentation of social phobic symptom response to the selective serotonin reuptake inhibitors (SSRIs). Ten patients meeting DSM-III-R criteria for generalized social phobia were studied. Patients obtaining only a partial response to an adequate trial of an SSRI, received buspirone in addition to the SSRI for 8 weeks in an open trial. Seven patients (70%) were considered responders (moderate or marked improvement) and 3 (30%) were considered nonresponders (minimal improvement or no change). This study provides clinical evidence suggesting that buspirone augmentation may be a useful clinical strategy in social phobic patients who show a partial response to an SSRI.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Van Ameringen M,Mancini C,Wilson C

doi

10.1016/0165-0327(96)00030-4

subject

Has Abstract

pub_date

1996-07-08 00:00:00

pages

115-21

issue

2

eissn

0165-0327

issn

1573-2517

pii

0165-0327(96)00030-4

journal_volume

39

pub_type

杂志文章

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