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Cognitive behavioral therapy is effective in misophonia: An open trial.

Abstract：

BACKGROUND:Misophonia is a psychiatric disorder in which ordinary human sounds like smacking or chewing provoke intense anger and disgust. Despite the high burden of this condition, to date there is no evidence-based treatment available. In this study we evaluated the efficacy of cognitive behavioral therapy (CBT) and investigated whether clinical or demographic characteristics predicted treatment response. METHODS:Ninety patients with misophonia received eight bi-weekly group CBT sessions. Treatment response was defined as a Clinical Global Impression - Improvement Scale (CGI-I) score at endpoint of 1 or 2 (very much or much improved) and a 30% or greater reduction on the Amsterdam Misophonia Scale (A-MISO-S), a measure of the severity of misophonia symptoms. RESULTS:Following treatment 48% (N=42) of the patients showed a significant reduction of misophonia symptoms. Severity of misophonia and the presence of disgust were positive predictors of treatment response. LIMITATIONS:The A-MISO-S is not a validated scale. Furthermore, this was an open-label study with a waiting list control condition. CONCLUSIONS:This is the first treatment study for misophonia. Our results suggest that CBT is effective in half of the patients.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Schröder AE,Vulink NC,van Loon AJ,Denys DA

doi

10.1016/j.jad.2017.04.017

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

289-294

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(16)32168-1

journal_volume

217

pub_type

临床试验,杂志文章

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