Onset of remission and relapse in depression: testing operational criteria through course description in a second Dublin cohort of first-admission participants.

Abstract:

BACKGROUND:This paper extends previous work describing course in depression using a recommended operational model that defines remission onset and relapse. We test whether a similar course pattern would emerge using this model in a new cohort of depressed participants. METHODS:We recruited a cohort of 86 participants, first-time inpatients, with DSM-IV major depression. Outcome was assessed prospectively over a 13-month minimum follow-up period. Remission onset was defined as a Ham-D score <8 for two consecutive weeks; relapse as a Ham-D score >16 for two consecutive weeks and meeting DSM-IV criteria for major depressive disorder. RESULTS:The cumulative probability of remission onset was 0.62 (SE=0.05) and 0.80 (SE=0.05) at 3 and 6 months following study entry. The relapse risk was 0.28 (SE=0.05) at 6 months post remission onset; 53% of those relapsing did so in the first 2 months post remission onset. Predictors of longer times to remission onset included: longer illness length, higher anxiety scores and unemployment; higher anxiety scores predicted relapse. The course pattern is similar to that reported previously. LIMITATIONS:These findings apply to inpatients only. Course was not rated blind to all of the participants' baseline data. CONCLUSIONS:Defining remission onset and relapse using this model is associated with a replicable course pattern. A singular clinical advantage of the model is the identification of those participants at highest risk of relapse 2 months post remission onset.

journal_name

J Affect Disord

authors

O'Leary D,Hickey T,Lagendijk M,Webb M

doi

10.1016/j.jad.2010.02.107

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

221-6

issue

1-3

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(10)00209-0

journal_volume

125

pub_type

杂志文章
  • The role of adverse life events on depression in older adults with ADHD.

    abstract:BACKGROUND:Comorbidity between Attention-Deficit/Hyperactivity Disorder (ADHD) and depression is high, also in older adults. Thus far it is not well understood why ADHD and depression are so strongly interrelated. One factor that may play a role in older adults with ADHD is an increased risk of experiencing adverse lif...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.11.048

    authors: Semeijn EJ,Comijs HC,Kooij JJ,Michielsen M,Beekman AT,Deeg DJ

    更新日期:2015-03-15 00:00:00

  • Secular trends in psychiatric diagnoses of suicide victims.

    abstract::Post-mortem psychiatric diagnoses are compared in two cohorts of male suicides from St. Louis (1956-1957) (Robins, 1981) and San Diego (1981-1982) (Rich et al., 1986). Similar structured interviews and diagnostic criteria had been used in both assessments. Substance/alcohol abuse has remained the major diagnosis in su...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(91)90059-2

    authors: Carlson GA,Rich CL,Grayson P,Fowler RC

    更新日期:1991-02-01 00:00:00

  • Interaction of 5-HTTLPR genotype and unipolar major depression in the emergence of aggressive/hostile traits.

    abstract:OBJECTIVE:The 5-HTTLPR polymorphism has been associated both with depression and aggression/hostility. The multidirectional association between depression, aggression and the s allele may be important, since all these phenomena are related to suicidal behavior. Our aim was to investigate the association between 5-HTTLP...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2011.03.029

    authors: Gonda X,Fountoulakis KN,Csukly G,Bagdy G,Pap D,Molnár E,Laszik A,Lazary J,Sarosi A,Faludi G,Sasvari-Szekely M,Szekely A,Rihmer Z

    更新日期:2011-08-01 00:00:00

  • Intermediate: cognitive phenotypes in bipolar disorder.

    abstract:BACKGROUND:Intermediate cognitive phenotypes (ICPs) are measurable and quantifiable states that may be objectively assessed in a standardized method, and can be integrated into association studies, including genetic, biochemical, clinical, and imaging based correlates. The present study used neuropsychological measures...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2009.08.018

    authors: Langenecker SA,Saunders EF,Kade AM,Ransom MT,McInnis MG

    更新日期:2010-05-01 00:00:00

  • Iowa Gambling Task performance in euthymic bipolar I disorder: a meta-analysis and empirical study.

    abstract:BACKGROUND:The Iowa Gambling Task (IGT) has been recommended as an index of reward sensitivity, which is elevated in bipolar disorder. We conducted a meta-analysis of IGT performance in euthymic bipolar I disorder compared with control participants. Findings indicated that people with bipolar disorder make more risky c...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jad.2012.11.027

    authors: Edge MD,Johnson SL,Ng T,Carver CS

    更新日期:2013-08-15 00:00:00

  • Early emotional disturbances during nicotine patch therapy in subjects with and without a history of depression.

    abstract:BACKGROUND:The goal of this study was to compare development of emotional symptomatology during smoking cessation with transdermal nicotine patches in subjects with and without a history of depression. METHODS:Twenty-five subjects, 14 with a history of depression and 11 without such a history, were evaluated before be...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(01)00468-2

    authors: Carton S,Le Houezec J,Lagrue G,Jouvent R

    更新日期:2002-11-01 00:00:00

  • Efficacy and safety of adjunctive therapy using esketamine or racemic ketamine for adult treatment-resistant depression: A randomized, double-blind, non-inferiority study.

    abstract:BACKGROUND:Ketamine and its enantiomers have recently been highlighted as one of the most effective therapeutic options in refractory depression. However, racemic ketamine and esketamine have not been directly compared. The aim of this study is to assess the efficacy and safety of esketamine compared to ketamine in pat...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.11.086

    authors: Correia-Melo FS,Leal GC,Vieira F,Jesus-Nunes AP,Mello RP,Magnavita G,Caliman-Fontes AT,Echegaray MVF,Bandeira ID,Silva SS,Cavalcanti DE,Araújo-de-Freitas L,Sarin LM,Tuena MA,Nakahira C,Sampaio AS,Del-Porto JA,Turecki G

    更新日期:2020-03-01 00:00:00

  • Differentiating bipolar disorder from borderline personality disorder: Diagnostic accuracy of the difficulty in emotion regulation scale and personality inventory for DSM-5.

    abstract:BACKGROUND:Confusion abounds when differentiating the diagnoses of bipolar disorder (BD) from borderline personality disorder (BPD). This study explored the relative clinical utility of affective instability and self-report personality trait measures for accurate identification of BD and BPD. METHODS:Receiver operator...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.11.079

    authors: Fowler JC,Madan A,Allen JG,Oldham JM,Frueh BC

    更新日期:2019-02-15 00:00:00

  • Proposed subtypes of bipolar II and related disorders: with hypomanic episodes (or cyclothymia) and with hyperthymic temperament.

    abstract::In an attempt to improve the classification of Bipolar II disorders, we have examined a consecutive series of 687 primary major depressives: 5.1% gave a past history of mania (Bipolar I), 13.7% met our operational criteria for hypomania (Bipolar II), and the remaining 81.2% were provisionally categorized as 'unipolar....

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(92)90044-7

    authors: Cassano GB,Akiskal HS,Savino M,Musetti L,Perugi G

    更新日期:1992-10-01 00:00:00

  • Efficacy of light therapy for a college student sample with non-seasonal subthreshold depression: An RCT study.

    abstract:BACKGROUND:Light therapy has been successfully used to treat seasonal and non-seasonal depression, but there is limited evidence for its efficacy in subthreshold depression. This study examines the efficacy of light therapy for symptoms of depression and anxiety in non-seasonal subthreshold depression. METHODS:College...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.08.055

    authors: Jiang L,Zhang S,Wang Y,So KF,Ren C,Tao Q

    更新日期:2020-12-01 00:00:00

  • Medically serious versus non-serious suicide attempts: relationships of lethality and intent to clinical and interpersonal characteristics.

    abstract:BACKGROUND:The study of near-fatal suicide attempts may provide insight into the minds of suicidal subjects. The aim of the study was to investigate the relationship of intent and lethality in medically serious and medically non-serious suicide attempts and to examine relationship of specific psychological and clinical...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2011.11.035

    authors: Horesh N,Levi Y,Apter A

    更新日期:2012-02-01 00:00:00

  • Comparison of inflammatory cytokine levels among type I/type II and manic/hypomanic/euthymic/depressive states of bipolar disorder.

    abstract:OBJECTIVE:Inflammatory cytokines have been suggested to be the trait or state markers of bipolar disorder, but with inconsistent results. This may be related to small sample sizes and poor control of some important confounding factors. METHODS:Gender/age-matched outpatients with bipolar disorder and normal controls we...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.05.009

    authors: Bai YM,Su TP,Tsai SJ,Wen-Fei C,Li CT,Pei-Chi T,Mu-Hong C

    更新日期:2014-09-01 00:00:00

  • Interpretation bias in social anxiety: A systematic review and meta-analysis.

    abstract:BACKGROUND:Interpretation bias, which involves interpreting ambiguous social events negatively and catastrophising even mildly negative social events, has been suggested as a key maintenance factor of Social Anxiety Disorder. Although some individual studies and narrative reviews have demonstrated a role for negative i...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,评审

    doi:10.1016/j.jad.2020.07.121

    authors: Chen J,Short M,Kemps E

    更新日期:2020-11-01 00:00:00

  • Gender differences in unipolar depression: a general population survey of adults between age 18 to 64 of German nationality.

    abstract:BACKGROUND:Several studies from different epidemiological backgrounds have shown that unipolar depression is more prevalent in females than in males. This study examines gender differences in depression in a sample of 4075 probands recruited representatively from the general population in the northern German epidemiolo...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(02)00121-0

    authors: Lucht M,Schaub RT,Meyer C,Hapke U,Rumpf HJ,Bartels T,von Houwald J,Barnow S,Freyberger HJ,Dilling H,John U

    更新日期:2003-12-01 00:00:00

  • Perceived stress and mental health: The mediating roles of social support and resilience among black women exposed to sexual violence.

    abstract:BACKGROUND:Black women disproportionately suffer from violence and its subsequent mental health outcomes. Increasing levels of perceived stress are associated with greater symptoms of depression and post-traumatic stress disorder (PTSD). Social support and resilience can potentially mediate the negative consequences of...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.08.037

    authors: Catabay CJ,Stockman JK,Campbell JC,Tsuyuki K

    更新日期:2019-12-01 00:00:00

  • Social support and depressive symptom disparity between urban and rural older adults in China.

    abstract:BACKGROUND:Depressive symptom disparity between urban and rural older adults is an important public health issue in China. Social support is considered as an effective way to alleviate depression of older adults. This study aimed to investigate the extent to which social support could explain the depressive symptom dis...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.04.076

    authors: Hu H,Cao Q,Shi Z,Lin W,Jiang H,Hou Y

    更新日期:2018-09-01 00:00:00

  • Comparison of objective and subjective assessments of sleep time in subjects with bipolar disorder.

    abstract:INTRODUCTION:Sleep disturbance is a core feature of bipolar disorder. To date there are a limited number of studies that compare subjective and objective measures of sleep in populations of subjects with mood disorders. This study evaluated the relationship between subjective and objective measurements of total sleep t...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2013.02.013

    authors: Gonzalez R,Tamminga C,Tohen M,Suppes T

    更新日期:2013-07-01 00:00:00

  • Bipolar disorder and self-stigma: A comparison with schizophrenia.

    abstract:AIM:Even though numerous studies have focused on the effects of self-stigma on patients with schizophrenia, little is known about self-stigma of patients with bipolar disorder (BD). In this study, a self-administered scale of self-stigmatising attitudes of patients with BD and schizophrenia was used to explore these at...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.05.038

    authors: Karidi MV,Vassilopoulou D,Savvidou E,Vitoratou S,Maillis A,Rabavilas A,Stefanis CN

    更新日期:2015-09-15 00:00:00

  • Reduced integrity of the uncinate fasciculus and cingulum in depression: A stem-by-stem analysis.

    abstract:INTRODUCTION:The subgenual cingulate gyrus (Brodmann's Area 25: BA25) is hypermetabolic in depression and has been targeted successfully with deep brain stimulation. Two of the white matter tracts that play a role in treatment response are the uncinate fasciculus (UF) and the cingulum bundle. The UF has three prefronta...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.04.055

    authors: Bhatia KD,Henderson LA,Hsu E,Yim M

    更新日期:2018-08-01 00:00:00

  • Risk of developing major depression and anxiety disorders among women with endometriosis: A longitudinal follow-up study.

    abstract:BACKGROUNDS:Several cross-sectional studies suggested a link between endometriosis and mood disorders. However, the temporal association between endometriosis and mood disorders (depression and anxiety disorders) is still unclear. METHODS:Using the Taiwan National Health Insurance Research Database, 10,439 women with ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.10.030

    authors: Chen LC,Hsu JW,Huang KL,Bai YM,Su TP,Li CT,Yang AC,Chang WH,Chen TJ,Tsai SJ,Chen MH

    更新日期:2016-01-15 00:00:00

  • Does a history of substance abuse and illness chronicity predict increased impulsivity in bipolar disorder?

    abstract:BACKGROUND:Impulsivity is a common feature shared by bipolar disorder (BD) and substance use disorder (SUD). SUD and recurrent mood episodes are considered to be risk factors for poor outcome in BD. However, the association between impulsivity, illness chronicity and SUD in BD remains unexplored. METHODS:103 BD patien...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.03.010

    authors: Bauer IE,Meyer TD,Sanches M,Zunta-Soares G,Soares JC

    更新日期:2015-07-01 00:00:00

  • Costs of the principal mood disorders: a study of comparative direct and indirect costs incurred by those with bipolar I, bipolar II and unipolar disorders.

    abstract:BACKGROUND:While there have been many studies comparing direct and indirect costs engendered individually and nationally by those with unipolar (UP) and bipolar (BP) disorders, there has been no previous study comparing costs across the bipolar I (BP I) and bipolar II (BP II) disorders. METHODS:We examine direct and i...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2012.10.002

    authors: Parker G,McCraw S,Hadzi-Pavlovic D,Fletcher K

    更新日期:2013-07-01 00:00:00

  • The role of emotion dysregulation in negative affect reactivity to a trauma cue: Differential associations through elicited posttraumatic stress disorder symptoms.

    abstract:BACKGROUND:Recent research has linked emotion dysregulation with increases in subjective ratings of negative affect (NA reactivity) to trauma reminders, a central symptom of posttraumatic stress disorder (PTSD). The current study adds to this burgeoning line of research by exploring elicited PTSD symptoms as a mechanis...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.02.028

    authors: Raudales AM,Weiss NH,Schmidt NB,Short NA

    更新日期:2020-04-15 00:00:00

  • The effect of adjunctive nutraceuticals in bipolar disorder: A systematic review of randomized placebo-controlled trials.

    abstract:BACKGROUND:Nutraceuticals are a group of compounds of growing interest for mental health professionals. Given the implication of certain nutrients in the onset of bipolar disorder, it has been hypothesized that nutraceuticals might be effective in improving symptoms of the condition (i.e. mania or depression). Our syst...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.04.039

    authors: Fusar-Poli L,Surace T,Vanella A,Meo V,Patania F,Furnari R,Signorelli MS,Aguglia E

    更新日期:2019-06-01 00:00:00

  • Delirious mania: clinical features and treatment response.

    abstract:OBJECTIVE:To examine clinical characteristics and treatment responses of patients presenting with delirium and mania to a psychiatric inpatient unit. METHOD:Chart review of 16 cases admitted to McLean Hospital with delirium and mania was conducted. We examined the demographics, psychiatric symptoms, clinical course, a...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2007.12.001

    authors: Karmacharya R,England ML,Ongür D

    更新日期:2008-08-01 00:00:00

  • A three-year longitudinal study of affective temperaments and risk for psychopathology.

    abstract:BACKGROUND:Affective temperaments are presumed to underlie bipolar psychopathology. The TEMPS-A has been widely used to assess affective temperaments in clinical and non-clinical samples. Cross-sectional research supports the association of affective temperaments and mood psychopathology; however, longitudinal research...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.04.006

    authors: DeGeorge DP,Walsh MA,Barrantes-Vidal N,Kwapil TR

    更新日期:2014-08-01 00:00:00

  • Bupropion and paroxetine differentially influence cardiovascular and neuroendocrine responses to stress in depressed patients.

    abstract:BACKGROUND:There exists a need to identify safe and effective treatments for depression in patients with coronary heart disease (CHD). METHODS:Using a cross-sectional design, 17 depressed patients being treated with bupropion (200-450 mg/day) were compared with 17 depressed patients being treated with paroxetine (10-5...

    journal_title:Journal of affective disorders

    pub_type: 临床试验,杂志文章

    doi:10.1016/S0165-0327(02)00352-X

    authors: Straneva-Meuse PA,Light KC,Allen MT,Golding M,Girdler SS

    更新日期:2004-04-01 00:00:00

  • Familial rates of affective and substance use disorders in patients with first-episode mania.

    abstract:BACKGROUND:One explanation for the high co-occurrence between bipolar and substance use disorders is that substance abuse may precipitate affective symptoms in patients who otherwise may have not had the genetic risk for developing an affective illness. Previous studies comparing familial rates of affective illness bet...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(99)00029-4

    authors: DelBello MP,Strakowski SM,Sax KW,McElroy SL,Keck PE Jr,West SA,Kmetz GF

    更新日期:1999-11-01 00:00:00

  • The associations between problematic Facebook use, psychological distress and well-being among adolescents and young adults: A systematic review and meta-analysis.

    abstract:BACKGROUND:A growing body of research has analyzed the potential risks of problematic Facebook use for mental health and well-being. The current meta-analysis is the first to examine the associations between problematic Facebook use, psychological distress (i.e., depression, anxiety, etc.) and well-being (life satisfac...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jad.2017.10.007

    authors: Marino C,Gini G,Vieno A,Spada MM

    更新日期:2018-01-15 00:00:00

  • History of perinatal loss: A study of psychological outcomes in mothers and fathers after subsequent healthy birth.

    abstract:BACKGROUND:The loss of an expected child is a psychologically difficult and potentially traumatic life event. While most women will become pregnant again within a year following the loss, data are limited regarding the mental health of parents with a history of perinatal loss, especially in the period following the bir...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.11.016

    authors: Faleschini S,Aubuchon O,Champeau L,Matte-Gagné C

    更新日期:2021-02-01 00:00:00