Identification of human and mouse homologs of the MC51L-53L-54L family of secreted glycoproteins encoded by the Molluscum contagiosum poxvirus.

abstract：:Homologous, subgenomic fragments of the viral LCR and E6/E7 transforming genes of HPV-18 and HPV-16 were amplified from several primary cervical, penile, and vulvar tumors and cloned into a pUC-18-derived vector. When assayed by a quantitative transformation assay using primary human keratinocytes, the subgenomic regi...

journal_title：Virology

authors： Villa LL,Schlegel R

更新日期：1991-03-01 00:00:00

abstract：:The most recent introduction of an avian influenza A virus without reassortment into mammals occurred in 1979 when H1N1 strains could be isolated from diseased pigs in northern Europe. This newly introduced avian virus formed a stable lineage in pigs and, in the meantime, spread all over Europe. In 1991 highly pathoge...

journal_title：Virology

authors： Ludwig S,Haustein A,Kaleta EF,Scholtissek C

更新日期：1994-07-01 00:00:00

abstract：:Human parainfluenza virus type 2 phosphoprotein (P) is an essential component of viral polymerase. The P gene encodes both P and accessory V proteins by a specific gene editing mechanism. Therefore, the N-terminal 164 amino acids of P protein are common to V protein. Interestingly, while P protein is located in the cy...

journal_title：Virology

authors： Ohtsuka J,Matsumoto Y,Ohta K,Fukumura M,Tsurudome M,Nosaka T,Nishio M

更新日期：2019-02-01 00:00:00

abstract：:Poliovirus procapsids, isolated and partially purified from infected HeLa cells, were found to dissociate into 14 S pentamers following freezing at -20 degrees overnight. Unlike pentameric subunits isolated directly from virus-infected cells or those obtained by alkaline treatment of procapsids, the "freeze-dissociate...

journal_title：Virology

authors： Onodera S,Phillips BA

更新日期：1987-08-01 00:00:00

abstract：:The 37K protein of Chinese wheat mosaic virus (CWMV) belongs to the 30K superfamily of plant virus movement proteins. CWMV 37K trans-complemented the cell-to-cell spread of a movement-defective Potato virus X. CWMV 37K fused to enhanced green fluorescent protein localized to plasmodesmata and formed endoplasmic reticu...

journal_title：Virology

authors： Andika IB,Zheng S,Tan Z,Sun L,Kondo H,Zhou X,Chen J

更新日期：2013-01-20 00:00:00

abstract：:Serotype 4 rotavirus strains have been classified into two antigenic "subtypes" by a solid phase immune electron microscopy technique in which cross-absorbed animal polyclonal immune sera are used as the source of antibodies. The sequences of the gene encoding the outer capsid glycoprotein VP7 from a single serotype 4...

journal_title：Virology

authors： Green KY,Sarasini A,Qian Y,Gerna G

更新日期：1992-05-01 00:00:00

abstract：:Adenovirus 12 (Ad12), but not adenovirus 2 or 5, induces metaphase chromosome fragility at four specific loci in humans: RNU1, RNU2, PSU1, and RN5S. As each of these sites corresponds to a tandemly repeated multigene family encoding a small, abundant structural RNA, we proposed that Ad12 hinders metaphase chromatin co...

journal_title：Virology

authors： Liao D,Yu A,Weiner AM

更新日期：1999-02-01 00:00:00

abstract：:Virus like particles (17 nm in diameter) associated with maize white line mosaic virus (MWLMV) were shown to be a satellite virus of MWLMV (SV-MWLMV) on the basis of the following properties: (1) The SV-MWLMV was dependent upon the presence of MWLMV for replication in maize, while the latter virus could replicate inde...

journal_title：Virology

authors： Zhang L,Zitter TA,Palukaitis P

更新日期：1991-02-01 00:00:00

abstract：:Rotavirus (RV) is the leading cause of infantile gastroenteritis worldwide. RV nonstructural protein 4 (NSP4), the first characterized viral enterotoxin, is a 28-kDa glycoprotein that has pleiotropic functions in RV infection and pathogenesis. NSP4 has multiple forms enabling it to perform its different functions. Dis...

journal_title：Virology

authors： Hyser JM,Zeng CQ,Beharry Z,Palzkill T,Estes MK

更新日期：2008-03-30 00:00:00

abstract：:Clones have been constructed containing full-length cDNA copies of PEBV RNA1 and RNA2, flanked by the CaMV 35 S RNA promoter and the nopaline synthase terminator. The clones are infectious when inoculated onto Nicotiana benthamiana plants. Both the viral RNAs and the virus particles were identified in infected plants....

journal_title：Virology

authors： MacFarlane SA,Gilmer D,Davies JW

更新日期：1992-04-01 00:00:00

abstract：:Hemorrhagic fever viruses are associated with rapidly progressing severe disease with high case fatality, making them of public health and biothreat importance. Effective antivirals are not available for most of the members of this diverse group of viruses. A broad spectrum strategy for antiviral development would be ...

journal_title：Virology

authors： Spiropoulou CF,Ranjan P,Pearce MB,Sealy TK,Albariño CG,Gangappa S,Fujita T,Rollin PE,Nichol ST,Ksiazek TG,Sambhara S

更新日期：2009-09-15 00:00:00

abstract：:A series of BglII- and Sau3A-derived fragments of phage T1 DNA were cloned into the plasmid vector pLV59 and the clones were tested for their ability to complement and recombine with infecting genomes of am mutants representing all known T1 essential genes. The resulting data were used to correlate the T1 genetic and ...

journal_title：Virology

authors： Liebeschuetz J,Ritchie DA

更新日期：1985-05-01 00:00:00

abstract：:The potential role(s) of cytokines in the reduction of infectious virus and persistent viral infection in the central nervous system was examined by determining the kinetics of cytokine mRNA expression following infection with the neurotropic JHM strain of mouse hepatitis virus. Mice were infected with an antibody esc...

journal_title：Virology

authors： Parra B,Hinton DR,Lin MT,Cua DJ,Stohlman SA

更新日期：1997-07-07 00:00:00

abstract：:The terminal sequences of both genomic dsRNA segments of different strains of infectious bursal disease virus were determined. Analysis of the linear sequences revealed in the 5'-noncoding region of both segments the presence of a 32-nucleotide sequence with motifs conserved between segments and serotypes. The 3'-nonc...

journal_title：Virology

authors： Mundt E,Müller H

更新日期：1995-05-10 00:00:00

abstract：:Coxsackievirus B3 (CVB3) is nonenveloped and has a single-stranded positive-sense RNA genome. CVB3 induces myocarditis and ultimately dilated cardiomyopathy. Although there are mounting evidences of an interaction between CVB3 particles and the cellular receptors, coxsackievirus and adenovirus receptor (CAR) and decay...

journal_title：Virology

authors： Chung SK,Kim JY,Kim IB,Park SI,Paek KH,Nam JH

更新日期：2005-03-01 00:00:00

abstract：:Multiplication of frog virus 3 (FV 3) occurs in mammalian cells provided they are incubated at temperatures lower than 33 degrees. The expression of the viral genome at supraoptimal temperatures was followed by analyzing the polypeptides produced in CHO-infected cells and comparing with those obtained under restrictiv...

journal_title：Virology

authors： Cordier O,Tondre L,Aubertin AM,Kirn A

更新日期：1986-07-30 00:00:00

abstract：:Human papillomavirus type 16 E7 protein, expressed in Escherichia coli as fusion protein lac alpha peptide-E7 (lac-E7), was purified by electrophoresis and used to immunize rabbits to raise antisera. The anti-lac-E7 sera recognized another bacterially expressed fusion protein trpE-E7 by the Western blot method. The an...

journal_title：Virology

authors： Sato H,Watanabe S,Furuno A,Yoshiike K

更新日期：1989-05-01 00:00:00

abstract：:Bacteriophage T4 tails contain a set of extended protein molecules in the central channel of the tail tube through which the DNA must exit during infection. Treatment of tails with guanidine hydrochloride separates the baseplates, leaving the tail tube and several specific tube-associated proteins. Methods were develo...

journal_title：Virology

authors： Duda RL,Gingery M,Eiserling FA

更新日期：1986-06-01 00:00:00

abstract：:Bipartite geminiviruses are small, plant-infecting viruses with genomes composed of circular, single-stranded DNA molecules, designated A and B. Although they are closely related genetically, individual bipartite geminiviruses frequently exhibit host-specific adaptation. Two such viruses are bean golden mosaic virus (...

journal_title：Virology

authors： Petty IT,Carter SC,Morra MR,Jeffrey JL,Olivey HE

更新日期：2000-11-25 00:00:00

abstract：:Differing and sometimes conflicting data have been reported regarding several aspects of vaccinia virus (VV) entry. To address this, we used a beta-galactosidase reporter virus to monitor virus entry into multiple cell types under varying conditions. Entry into HeLa, B78H1 and L cells was strongly inhibited by heparin...

journal_title：Virology

authors： Whitbeck JC,Foo CH,Ponce de Leon M,Eisenberg RJ,Cohen GH

更新日期：2009-03-15 00:00:00

abstract：:Assembly of icosahedral capsids of proper size and symmetry is not understood. Residue F170 in bacteriophage P22 coat protein is critical for conformational switching during assembly. Substitutions at this site cause assembly of tubes of hexamerically arranged coat protein. Intragenic suppressors of the ts phenotype o...

journal_title：Virology

authors： Suhanovsky MM,Teschke CM

更新日期：2011-09-01 00:00:00

abstract：:Viruses that establish latent infection must maintain their DNA in the host nucleus through many cellular generations. Here we identify a novel mechanism by which the gammaherpesvirus Kaposi's sarcoma-associated herpesvirus (KSHV) may achieve this persistence in latently infected body cavity-based lymphoma (BCBL) cell...

journal_title：Virology

authors： Cotter MA 2nd,Robertson ES

更新日期：1999-11-25 00:00:00

abstract：:Viroids are small, nontranslatable pathogenic RNAs that replicate autonomously and traffic systemically in their host plants. We have used in situ hybridization to analyze the trafficking pattern of Potato spindle tuber viroid (PSTVd) in tomato and Nicotiana benthamiana. When PSTVd was inoculated onto the stem of a pl...

journal_title：Virology

authors： Zhu Y,Green L,Woo YM,Owens R,Ding B

更新日期：2001-01-05 00:00:00

abstract：:The antibody response in serum and the reproductive tract of female rabbits to a model antigen, influenza virus haemagglutinin (HA), encoded by a recombinant myxoma virus was investigated. Strong and lasting IgG antibody responses to HA were induced in serum following intradermal, intranasal, and intravaginal immunisa...

journal_title：Virology

authors： Gu W,Holland M,Janssens P,Kerr P

更新日期：2003-08-15 00:00:00

abstract：:The coding region of segment 4 of Thogoto (THO) virus, a tick-borne member of the Orthomyxoviridae, was expressed in a baculovirus system under the control of the polyhedrin promoter. This construct expressed authentic envelope glycoprotein as determined by size and antigenic reactivity with a panel of monoclonal anti...

journal_title：Virology

authors： Jones LD,Morse MA,Marriott AC,Nuttall PA

更新日期：1995-10-20 00:00:00

abstract：:Autographa californica multiple nucleopolyhedrovirus (AcMNPV) ac142 is a baculovirus core gene and encodes a protein previously shown to associate with occlusion-derived virus (ODV). To determine its role in the baculovirus life cycle, we used the AcMNPV bacmid system to generate an ac142 deletion virus (AcBAC(ac142KO...

journal_title：Virology

authors： McCarthy CB,Dai X,Donly C,Theilmann DA

更新日期：2008-03-15 00:00:00

abstract：:The monocytoid tumor cell line U-937 and five derived subclones were infected with the HTLV-IIIB isolate of the human immunodeficiency virus (HIV). Susceptibility to infection and sensitivity to the cytopathic effects correlated with the expression of the T4 antigen on the cell surface. On the basis of these character...

journal_title：Virology

authors： Asjö B,Ivhed I,Gidlund M,Fuerstenberg S,Fenyö EM,Nilsson K,Wigzell H

更新日期：1987-04-01 00:00:00

abstract：:Phage PR4 contains a lipid bilayer within the phage protein capsid. The phospholipids of the bilayer are derived from those of the host. We report that phage morphogenesis selects against the unusually bulky phospholipids synthesized by Escherichia coli grown in the presence of various sugar alcohols. These data indic...

journal_title：Virology

authors： Myung H,Cronan JE Jr

更新日期：1994-01-01 00:00:00

abstract：:The genome of peanut clump pecluvirus (PCV) consists of two messenger RNA components which contain, respectively, three and five open reading frames (ORFs). Inoculation of transcripts from full-length cDNA clones derived from the PCV RNAs showed that RNA-1 is able to replicate in the absence of RNA-2 in protoplasts, b...

journal_title：Virology

authors： Herzog E,Hemmer O,Hauser S,Meyer G,Bouzoubaa S,Fritsch C

更新日期：1998-09-01 00:00:00

abstract：:Infection of rhesus macaques with attenuated SIVmac is, at present, the only strategy which confers significant protection from challenge with wild-type SIVmac grown in monkey PBMC. However, initial results suggest that the protective mechanism does not develop until late after "vaccination" (approx 10 months). As par...

journal_title：Virology

authors： Norley S,Beer B,Binninger-Schinzel D,Cosma C,Kurth R

更新日期：1996-05-01 00:00:00