The chemical stability and sterility of sodium thiopental after preparation.

abstract：BACKGROUND:Although music is frequently used to promote a relaxing environment during labor and delivery, the effect of its use during the placement of neuraxial techniques is unknown. Our study sought to determine the effects of music use on laboring parturients during epidural catheter placement, with the hypothesis ...

journal_title：Anesthesia and analgesia

authors： Drzymalski DM,Tsen LC,Palanisamy A,Zhou J,Huang CC,Kodali BS

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Three cases of drug-induced liver injury (DILI) have been reported after desflurane anesthesia. However, no previous reports have detected serum autoantibodies such as that reported with DILI from halothane or isoflurane. METHODS AND RESULTS:We describe the first documentation of cytochrome P450 2E1 IgG4 au...

journal_title：Anesthesia and analgesia

authors： Anderson JS,Rose NR,Martin JL,Eger EI,Njoku DB

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Xenon has many characteristics that make it very attractive as an anesthetic and therapeutic drug. Unfortunately, the supply of xenon is fixed, and therefore reclamation and recovery from even the most efficient breathing circuits is desirable. We built and evaluated a cryogenic device to recover xenon from ...

journal_title：Anesthesia and analgesia

authors： Dingley J,Mason RS

更新日期：2007-11-01 00:00:00

abstract：:The purpose of this study was to measure cardiac sympathetic nerve activity (CSNA) and atrioventricular (AV) conduction and to test the effects of dobutamine (DOB) and phenylephrine (PHE) on AV conduction during combined use of halothane and thoracic epidural lidocaine. Cats were anesthetized with 1 % halothane and an...

journal_title：Anesthesia and analgesia

authors： Nishikawa K,Yabe M,Mori T,Terai T,Yukioka H,Fujimori M

更新日期：1996-03-01 00:00:00

abstract：:Electroconvulsive therapy (ECT) is a highly effective treatment for severe depression. However, its use is associated with significant posttreatment cognitive impairment. Magnetic seizure therapy (MST) was developed as an alternative therapy that could reduce postseizure side effects through the induction of more "foc...

journal_title：Anesthesia and analgesia

authors： White PF,Amos Q,Zhang Y,Stool L,Husain MM,Thornton L,Downing M,McClintock S,Lisanby SH

更新日期：2006-07-01 00:00:00

abstract：UNLABELLED:The enhancing action of propofol on gamma-amino-n-butyric acid subtype A (GABA(A)) receptors purportedly underlies its anesthetic effects. However, a recent study found that a GABA(A) antagonist did not alter the capacity of propofol to depress the righting reflex. We examined whether the noncompetitive GABA...

journal_title：Anesthesia and analgesia

authors： Sonner JM,Zhang Y,Stabernack C,Abaigar W,Xing Y,Laster MJ

更新日期：2003-03-01 00:00:00

abstract：:Halothane, enflurane, isoflurane, and fentanyl were examined for their potential to exacerbate liver dysfunction in rats with preexisting cirrhosis. Male Wistar rats given sodium phenobarbital for 2 weeks are assigned randomly to two groups. One group (cirrhotic) was exposed by inhalation to carbon tetrachloride (CCl4...

journal_title：Anesthesia and analgesia

authors： Baden JM,Kundomal YR,Luttropp ME Jr,Maze M,Kosek JC

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:The etiology of postoperative cognitive decline (POCD) remains to be determined. Anesthetic isoflurane, but not desflurane, may induce neurotoxicity. However, the functional consequences of these effects have not been assessed. We therefore performed a pilot study to determine the effects of isoflurane and d...

journal_title：Anesthesia and analgesia

authors： Zhang B,Tian M,Zhen Y,Yue Y,Sherman J,Zheng H,Li S,Tanzi RE,Marcantonio ER,Xie Z

更新日期：2012-02-01 00:00:00

abstract：:Nitrous oxide increases peripheral vascular tone in animals and humans and constricts epicardial coronary arteries in dogs. Current studies sought both to determine whether nitrous oxide caused epicardial coronary artery constriction in a second animal species, pigs, and to investigate mechanisms. Left anterior descen...

journal_title：Anesthesia and analgesia

authors： Hughes JM,Sill JC,Pettis M,Rorie DK

更新日期：1993-08-01 00:00:00

abstract：:External cephalic version is a technique that decreases the need for cesarean delivery in patients with breech presentation. Several techniques exist to increase the success of external cephalic version; however, there are no studies comparing different tocolytics in patients who also received neuraxial anesthesia. We...

journal_title：Anesthesia and analgesia

authors： Katz D,Riley K,Kim E,Beilin Y

更新日期：2020-03-01 00:00:00

abstract：:Lumbar cerebrospinal fluid levels of 5-hydroxyindoleacetic acid, which are used as indicators of central nervous system serotonergic neuronal activity, were significantly higher in 67 patients with chronic pain and in 32 patients with acute pain (23.6 +/- 3.3 and 23.1 +/- 3.8, respectively) than in 30 patients (8.8 +/...

journal_title：Anesthesia and analgesia

authors： Ghia JN,Mueller RA,Duncan GH,Scott DS,Mao W

更新日期：1981-12-01 00:00:00

abstract：:Sufentanil is a potent opioid that occasionally has been associated with hypotension. The mechanism behind this hypotension is unclear. We hypothesized that sufentanil had a direct effect on vascular smooth muscle to cause vasodilation. Sufentanil was infused into the brachial artery of 10 young, healthy volunteers at...

journal_title：Anesthesia and analgesia

authors： Ebert TJ,Ficke DJ,Arain SR,Holtz MN,Shankar H

更新日期：2005-12-01 00:00:00

abstract：:Many in vitro effects of volatile anesthetics are known, but the mechanisms of action are still under debate. Because suppression of sensory perception is one of the major goals of general anesthesia, we studied the effects of isoflurane on the processing of somatosensory information in anesthetized rats. Local iontop...

journal_title：Anesthesia and analgesia

authors： Vahle-Hinz C,Detsch O,Siemers M,Kochs E,Bromm B

更新日期：2001-06-01 00:00:00

abstract：:The role of succinylcholine in the precipitation of malignant hyperthermia (MH) necessitates the testing of new neuromuscular relaxants for their ability to trigger MH in MH-susceptible swine before general human use. We tested doxacurium and mivacurium, two new nondepolarizing bis-benzylisoquinolinium neuromuscular r...

journal_title：Anesthesia and analgesia

authors： Sufit RL,Kreul JF,Bellay YM,Helmer P,Brunson DB,Will J

更新日期：1990-09-01 00:00:00

abstract：UNLABELLED:Concern about the side effects of allogeneic red blood cell transfusion has increased interest in methods of minimizing perioperative transfusion. We performed meta-analyses of randomized trials evaluating the efficacy and safety of aprotinin, desmopressin, tranexamic acid, and epsilon-aminocaproic acid in c...

journal_title：Anesthesia and analgesia

authors： Laupacis A,Fergusson D

更新日期：1997-12-01 00:00:00

abstract：:We studied three groups of patients without previous renal impairment, undergoing elective coronary artery bypass surgery. Group H (n = 7) underwent open heart surgery using moderate hypothermia (28 degrees C); Groups N and M (n = 8, each) were managed at normothermia. The extracorporeal circuit was primed with Hartma...

journal_title：Anesthesia and analgesia

authors： Ip-Yam PC,Murphy S,Baines M,Fox MA,Desmond MJ,Innes PA

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Sepsis is currently the leading cause of direct maternal death in the United Kingdom. In this study, we aimed to determine frequency, temporal trends, and independent associations for severe sepsis during hospitalization for delivery in the United States. METHODS:Data were obtained from the Nationwide Inpat...

journal_title：Anesthesia and analgesia

authors： Bauer ME,Bateman BT,Bauer ST,Shanks AM,Mhyre JM

更新日期：2013-10-01 00:00:00

abstract：UNLABELLED:The isolated effects of hypothermia on hemostasis have not been investigated in healthy humans. We cooled 16 anesthetized patients scheduled for elective intracranial surgery to 32 degrees C body core temperature and assessed prothrombin time (PT), activated partial thromboplastin time, thrombelastogram (TEG...

journal_title：Anesthesia and analgesia

authors： Kettner SC,Sitzwohl C,Zimpfer M,Kozek SA,Holzer A,Spiss CK,Illievich UM

更新日期：2003-06-01 00:00:00

abstract：:Changes in cardiac output in response to augmenting cardiac contractility, preload, and heart rate during enflurane anesthesia were examined in 12 open-chested dogs. Cardiac contractility was assessed by the slope of the end-systolic pressure-volume relation (Emax). Dobutamine (3, 6, and 9 micrograms.kg-1.min-1) was a...

journal_title：Anesthesia and analgesia

authors： Sato M,Hoka S,Arimura H,Ono K,Yoshitake J

更新日期：1991-11-01 00:00:00

abstract：UNLABELLED:We compared the ketoprofen-propacetamol combination relative to propacetamol alone in thyroid and parathyroid surgery in terms of postoperative analgesic efficacy, bleeding, and incidence of nausea and vomiting to determine whether ketoprofen results in any benefit in this type of surgery. Patients were dist...

journal_title：Anesthesia and analgesia

authors： Basto ER,Waintrop C,Mourey FD,Landru JP,Eurin BG,Jacob LP

更新日期：2001-04-01 00:00:00

abstract：UNLABELLED:Thiamylal, a chiral thiobarbiturate, is marketed as a racemic product. We studied the serum protein binding and microsomal metabolism of thiamylal enantiomers in vitro. The unbound fraction of R(+)-thiamylal was greater than that of S(-)-thiamylal. The analysis of binding data revealed that both enantiomers ...

journal_title：Anesthesia and analgesia

authors： Sueyasu M,Fujito K,Shuto H,Mizokoshi T,Kataoka Y,Oishi R

更新日期：2000-09-01 00:00:00

abstract：:Seven anesthetized patients were studied to determine the interaction between pancuronium and lincomycin and the ability of neostigmine and 4-aminopyridine to antagonize the block. Lincomycin 600 mg given IV alone did not decrease twitch tension. An 8 to 10% decrease in twitch tension occurred when lincomycin was give...

journal_title：Anesthesia and analgesia

authors： Booij LH,Miller RD,Crul JF

更新日期：1978-05-01 00:00:00

abstract：INTRODUCTION:Exposure to isoflurane before and during early reperfusion protects against myocardial infarction by activating phosphatidylinositol-3-kinase (PI3K)-mediated signaling. The apoptotic protein, p53, is regulated by PI3K, and inhibition of p53 protects against ischemic injury. We tested the hypothesis that p5...

journal_title：Anesthesia and analgesia

authors： Venkatapuram S,Wang C,Krolikowski JG,Weihrauch D,Kersten JR,Warltier DC,Pratt PF Jr,Pagel PS

更新日期：2006-12-01 00:00:00

abstract：UNLABELLED:Despite the widespread use of methadone for the treatment of acute and chronic pain, the hemodynamic effects of methadone administered by IV bolus have not been studied. We compared the hemodynamic effects of an IV bolus of methadone 20 mg with those of fentanyl 10 microg/kg for the induction of anesthesia i...

journal_title：Anesthesia and analgesia

authors： Bowdle TA,Even A,Shen DD,Swardstrom M

更新日期：2004-06-01 00:00:00

abstract：UNLABELLED:Perturbation of respiratory mechanics produced by general anesthesia and surgery is more pronounced in morbidly obese (MO) patients. Because general anesthesia induces pulmonary atelectasis in nonobese patients, we hypothesized that atelectasis formation would be particularly significant in MO patients. We i...

journal_title：Anesthesia and analgesia

authors： Eichenberger A,Proietti S,Wicky S,Frascarolo P,Suter M,Spahn DR,Magnusson L

更新日期：2002-12-01 00:00:00

abstract：UNLABELLED:To evaluate the influence of needle type on the lateral distribution of 0.5% hyperbaric bupivacaine, 30 patients undergoing lower limb surgery were placed in the lateral position with the side to be operated on dependent and underwent dural puncture by either a 25-gauge Whitacre (n = 15) or a 25-gauge Quinck...

journal_title：Anesthesia and analgesia

authors： Casati A,Fanelli G,Cappelleri G,Aldegheri G,Leoni A,Casaletti E,Torri G

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Postoperative nausea (PON) is a common complication of anesthesia and surgery. Antiemetic medication for higher-risk patients may reduce but does not reliably prevent PON. We examined aromatherapy as a treatment for patients experiencing PON after ambulatory surgery. Our primary hypothesis was that in compar...

journal_title：Anesthesia and analgesia

authors： Hunt R,Dienemann J,Norton HJ,Hartley W,Hudgens A,Stern T,Divine G

更新日期：2013-09-01 00:00:00

abstract：:The dorsal raphe (DR) nucleus is a system of nuclei in the midline of the lower brainstem, which is considered one of the most important nuclei in the modulation of pain in the central nervous system. Central noradrenergic systems play an important role in the control of cardiovascular regulation and pain transmission...

journal_title：Anesthesia and analgesia

authors： Alojado ME,Ohta Y,Kemmotsu O

更新日期：1994-08-01 00:00:00

abstract：:Isoproterenol 5 micrograms may be an effective marker of accidental intravascular injection in women in labor; however, before isoproterenol can be incorporated in routinely used epidural test doses, the safety and usefulness should be determined in an animal model. This study was designed to examine the hemodynamic e...

journal_title：Anesthesia and analgesia

authors： Marcus MA,Vertommen JD,Van Aken H,Wouters PF

更新日期：1996-05-01 00:00:00

abstract：:Sevoflurane appears to have several properties that make it an attractive alternative to the currently available anesthetics for outpatient anesthesia. The relative low solubility of sevoflurane, as well as an impressive lack of airway irritation, makes it a very useful anesthetic for inhalation induction of anesthesi...

journal_title：Anesthesia and analgesia

authors： Smith I,Nathanson MH,White PF

更新日期：1995-12-01 00:00:00