Inhibition of apoptotic protein p53 lowers the threshold of isoflurane-induced cardioprotection during early reperfusion in rabbits.

abstract：BACKGROUND:Musculoskeletal deformities in mucopolysaccharidoses (MPSs) patients pose unique challenges when patients present for surgery, especially nonspinal surgery. MPS patients have developed postsurgical neurological deficits after nonspinal surgery. While the incidence of neurological deficits after nonspinal sur...

journal_title：Anesthesia and analgesia

authors： Kandil AI,Pettit CS,Berry LN,Busso VO,Careskey M,Chesnut E,Buck DW,Leslie ND,Tamai J,McAuliffe JJ,Chidambaran V

更新日期：2020-06-01 00:00:00

abstract：UNLABELLED:The last decade has witnessed a proliferation of devices or methods that facilitate intubation in difficult circumstances, maintain ventilation, or which do both. These all require properly functioning and specially designed apparatus, the use of which requires variable degrees of expertise. This technical c...

journal_title：Anesthesia and analgesia

authors： Beattie C

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Recently, we reported a new technique to augment motor-evoked potentials (MEPs) under general anesthesia, posttetanic MEP (p-MEP), in which tetanic stimulation of the peripheral nerve before transcranial stimulation enlarged amplitudes of MEPs from the muscle innervated by the nerve subjected to tetanic stim...

journal_title：Anesthesia and analgesia

authors： Hayashi H,Kawaguchi M,Yamamoto Y,Inoue S,Koizumi M,Ueda Y,Takakura Y,Furuya H

更新日期：2008-07-01 00:00:00

abstract：:The effects of commercial and crystalline solutions of chloroprocaine (CP) (1.6 X 10(-3)-0.4 X 10(-3)M) and sodium bisulfite (SB) (0.8 X 10(-3)-0.08 X 10(-3)M) were studied on the multiplication of human neuroblastoma cells. These cells were chosen because of putative neurotoxicity associated with CP; cell multiplicat...

journal_title：Anesthesia and analgesia

authors： Seravalli E,Lear E

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:The American Society of Anesthesiologists has announced that perioperative normothermia is a "Quality Incentive in Anesthesiology." We examined whether we could meet this quality incentive in a simple population: patients undergoing anesthesia for electroconvulsive therapy (ECT). METHODS:We compared infrare...

journal_title：Anesthesia and analgesia

authors： Modell JH,Gravenstein N,Morey TE

更新日期：2008-11-01 00:00:00

abstract：UNLABELLED:We used a double-blind design to study urodynamic changes induced by mu-agonists (fentanyl, morphine), a partial mu-agonist antagonist (buprenorphine), a putative mu-antagonist, kappa-agonist (nalbuphine), and ketoprofen, an injectable nonsteroidal antiinflammatory drug. Men (20-55 yr old) were randomly assi...

journal_title：Anesthesia and analgesia

authors： Malinovsky JM,Le Normand L,Lepage JY,Malinge M,Cozian A,Pinaud M,Buzelin JM

更新日期：1998-08-01 00:00:00

abstract：UNLABELLED:Whether tracheal intubation is more difficult in obese patients is debatable. We compared the incidence of difficult tracheal intubation in obese and lean patients by using a recently validated objective scale, the intubation difficulty scale (IDS). We studied 134 lean (body mass index, <30 kg/m2) and 129 ob...

journal_title：Anesthesia and analgesia

authors： Juvin P,Lavaut E,Dupont H,Lefevre P,Demetriou M,Dumoulin JL,Desmonts JM

更新日期：2003-08-01 00:00:00

abstract：UNLABELLED:Sudden profound hypotensive and/or bradycardic events (HBE) have been reported in >20% of patients undergoing shoulder arthroscopy in the sitting position under interscalene block anesthesia. Retrospective studies suggest that the administration of beta-blockers is safe and may decrease the incidence of thes...

journal_title：Anesthesia and analgesia

authors： Liguori GA,Kahn RL,Gordon J,Gordon MA,Urban MK

更新日期：1998-12-01 00:00:00

abstract：IMPLICATIONS:We report a unique case of acute anaphylaxis after mediastinal irrigation with a dilute bacitracin solution. ...

journal_title：Anesthesia and analgesia

authors： Blas M,Briesacher KS,Lobato EB

更新日期：2000-10-01 00:00:00

abstract：:The renal effects of pulsatile (pulse pressure 18.0 +/- 1.5 mm Hg [mean +/- SEM]) or nonpulsatile perfusion (mean pulse pressure 1.9 +/- 0.4 mm Hg) during either alpha-stat (mean PaCO2 41.2 +/- 0.9 mm Hg measured at 37 degrees C) or pH-stat (mean PaCO2 60.6 +/- 1.7 mm Hg measured at 37 degrees C) pH management of hypo...

journal_title：Anesthesia and analgesia

authors： Badner NH,Murkin JM,Lok P

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Mitochondrial injury is a major cause of sepsis-induced organ failure. Polydatin (PD), a natural polyphenol, demonstrates protective mitochondrial effects in neurons and arteriolar smooth muscle cells during severe shock. In this study, we investigated the effects of PD on renal tubular epithelial cell (RTEC...

journal_title：Anesthesia and analgesia

authors： Gao Y,Zeng Z,Li T,Xu S,Wang X,Chen Z,Lin C

更新日期：2015-11-01 00:00:00

abstract：UNLABELLED:We studied the in vitro effects of sevoflurane, isoflurane, and propofol anesthesia on platelet function. Thirty patients undergoing minor surgical procedures were divided into three groups (n = 10 each). Induction of anesthesia was achieved by using 5 mg/kg thiopental i.v., and 0.1 mg/kg vecuronium i.v. was...

journal_title：Anesthesia and analgesia

authors： Doğan IV,Ovali E,Eti Z,Yayci A,Göğüş FY

更新日期：1999-02-01 00:00:00

abstract：UNLABELLED:Acute withdrawal syndromes, including agitation and a long weaning time, are common adverse effects after long-term sedation with midazolam. We performed this study to determine whether the sequential use of midazolam and propofol could reduce adverse effects as compared with midazolam alone. We studied 26 p...

journal_title：Anesthesia and analgesia

authors： Saito M,Terao Y,Fukusaki M,Makita T,Shibata O,Sumikawa K

更新日期：2003-03-01 00:00:00

abstract：:To assess the evolution of satisfactory neohepatic graft function or failure, hemodynamic variables, along with data for oxygen delivery and utilization, were analyzed retrospectively in 99 patients undergoing orthotopic liver transplantation. Caval cross-clamping without venovenous bypass initiated a series of hemody...

journal_title：Anesthesia and analgesia

authors： Steltzer H,Hiesmayr M,Tüchy G,Zimpfer M

更新日期：1993-03-01 00:00:00

abstract：:Availability of physiologic monitoring equipment to ensure the safe administration of anesthesia is an expected standard in many parts of the world. Many hospitals in China may not have an adequate quantity and variety of anesthesia delivery and patient monitoring equipment to assure safe administration of anesthesia ...

journal_title：Anesthesia and analgesia

authors： Juan X,Xinqiao F,Shanglong Y,Yuguang H,Buwei Y,Shiying Y,Pengqian F,Hanqing Z

更新日期：2012-06-01 00:00:00

abstract：:Both epidural and general anesthetics alter autonomic balance. However, the relative differences between epidural (EA) and general anesthetics (GA) with regard to cardiac and peripheral sympathovagal balance have not been described. Twenty consecutive patients scheduled for radical retropubic prostatectomy were random...

journal_title：Anesthesia and analgesia

authors： Fleisher LA,Frank SM,Shir Y,Estafanous M,Kelly S,Raja SN

更新日期：1994-07-01 00:00:00

abstract：:The anesthetic effect of lidocaine was evaluated in rats by determining the change in anesthetic requirement of cyclopropane MAC that was produced by blood concentrations of lidocaine in the clinically useful range. A linear reduction in anesthetic requirement was produced with concentrations up to 1 mug/ml. Further i...

journal_title：Anesthesia and analgesia

authors： DiFazio CA,Neiderlehner JR,Burney RG

更新日期：1976-11-01 00:00:00

abstract：UNLABELLED:Percutaneous needle liver biopsy is an important procedure for the diagnosis and evaluation of liver disease and is frequently associated with pain. In this prospective study, we investigated the prevalence and characteristics of this pain syndrome. Fifty-four subjects, who underwent liver biopsy under ultra...

journal_title：Anesthesia and analgesia

authors： Eisenberg E,Konopniki M,Veitsman E,Kramskay R,Gaitini D,Baruch Y

更新日期：2003-05-01 00:00:00

abstract：:We studied the performance of a target-controlled drug infusion device, computer-assisted continuous infusion (CACI). Forty-one volunteers received one of midazolam (n = 11), propofol (n = 10), thiopental (n = 10), or fentanyl (n = 10) in sedative concentrations. Concentrations were kept constant for 45-70 min at five...

journal_title：Anesthesia and analgesia

authors： Veselis RA,Glass P,Dnistrian A,Reinsel R

更新日期：1997-05-01 00:00:00

abstract：UNLABELLED:Propofol and alfentanil are both rapid and short-acting drugs that can be used for sedation and analgesia during monitored anesthesia care (MAC). This study was designed to determine the optimal infusion rates of propofol and alfentanil when administered during local anesthesia. In this randomized, double-bl...

journal_title：Anesthesia and analgesia

authors： Avramov MN,White PF

更新日期：1997-09-01 00:00:00

abstract：UNLABELLED:One thousand questionnaires concerning the techniques and complications of intravenous regional anesthesia (IVRA) were sent to 900 American and 100 Canadian anesthesiologists. Of the 321 respondents, 86% perform IVRA regularly. A wide variation in device-related and clinical aspects was found, ranging from a...

journal_title：Anesthesia and analgesia

authors： Henderson CL,Warriner CB,McEwen JA,Merrick PM

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:The wide need for analgesia, anesthesia, and sedation in children and the lack of pediatric labeling leads to widespread off-label use of medications for pain and sedation in children. Any attempt to address the lack of labeling will require national estimates of the numbers of children using each medication...

journal_title：Anesthesia and analgesia

authors： Lasky T,Ernst FR,Greenspan J

更新日期：2012-11-01 00:00:00

abstract：:Because deviations from the Meyer-Overton rule may provide insights into the attributes of the anesthetic site of action, we characterized the solubility of the n-alkanes in various hydrophobic solvents (n-tetradecane, olive oil, n-octanol, and lecithin) as well as saline using variations on standard techniques. Incre...

journal_title：Anesthesia and analgesia

authors： Taheri S,Laster MJ,Liu J,Eger EI 2nd,Halsey MJ,Koblin DD

更新日期：1993-07-01 00:00:00

abstract：:Lidocaine decreases the minimum alveolar concentration (MAC) of inhaled anesthetics and has been used clinically to reduce the requirements for other anesthetic drugs. In this study we examined the effects of lidocaine on isoflurane MAC in cats. Six cats were studied. In Experiment 1, the MAC of isoflurane was determi...

journal_title：Anesthesia and analgesia

authors： Pypendop BH,Ilkiw JE

更新日期：2005-01-01 00:00:00

abstract：:The purpose of the present study was to quantify the inhibitory effect of inhaled halothane and isoflurane on acute hypercapnia-induced responses of capacitance-regulating veins and related cardiovascular variables in response to sequential 40-s periods of 5%, 10%, 15%, and 20% inspired CO2 (FICO2). Measurements were ...

journal_title：Anesthesia and analgesia

authors： Stekiel TA,Stekiel WJ,Tominaga M,Stadnicka A,Bosnjak ZJ,Kampine JP

更新日期：1996-02-01 00:00:00

abstract：:A well secured endotracheal tube is very essential for the safe conduct of anesthesia. In maxillofacial surgeries, providing secure fixation of the nasotracheal tube has always been a problem. We have used an infant feeding tube that goes around the nasal septum for the fixation of the nasal endotracheal tube. This me...

journal_title：Anesthesia and analgesia

authors： Bhat VR,Venkateshwaran G

更新日期：2004-11-01 00:00:00

abstract：:In recent years, there have been escalating concerns related to the opioid epidemic. With a steadily increasing opioid supply, it is critical to provide proper education to patients who are prescribed these medications. Education should be emphasized as a means of ensuring safe use and potentially as a strategy for cu...

journal_title：Anesthesia and analgesia

authors： Lee BH,Wu CL

更新日期：2020-03-01 00:00:00

abstract：UNLABELLED:Despite the widespread use of methadone for the treatment of acute and chronic pain, the hemodynamic effects of methadone administered by IV bolus have not been studied. We compared the hemodynamic effects of an IV bolus of methadone 20 mg with those of fentanyl 10 microg/kg for the induction of anesthesia i...

journal_title：Anesthesia and analgesia

authors： Bowdle TA,Even A,Shen DD,Swardstrom M

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Drug-induced sleep endoscopy (DISE) uses sedative-hypnotics to induce moderate obstruction in sleep apnea patients, thereby facilitating anatomic assessment of obstructive physiology. Implementation of DISE with propofol requires a dosing strategy that reliably and efficiently produces obstruction while mini...

journal_title：Anesthesia and analgesia

authors： Atkins JH,Mandel JE,Rosanova G

更新日期：2014-10-01 00:00:00

abstract：:The effects of enflurane and halothane anesthesia on systolic time intervals were studied in 12 healthy patients. Cardiovascular measurements were made at equipotent levels of anesthesia: enflurane 1.23% end-tidal and halothane 0.65% end-tidal. These agents were studied first with 50% N2O and then without N2O. Systoli...

journal_title：Anesthesia and analgesia

authors： Kaplan JA,Miller ED,Bailey DR

更新日期：1976-03-01 00:00:00