Hepatocyte growth factor and neutrophil elastase in idiopathic pulmonary fibrosis.

abstract：:Primary ciliary dyskinesia (PCD) is a genetic condition resulting in bronchiectasis. Exhaled gas nitric oxide (FE(NO)) is reduced in PCD. A model of pulmonary NO exchange dynamics can be used to demonstrate relative contributions of bronchial (J'aw(NO)) and peripheral airway (Calv(NO)) NO to the final FE(NO) concentra...

journal_title：Respiratory medicine

authors： Shoemark A,Wilson R

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:There are chronic forms of hypersensitivity pneumonitis (cHP) that can progress to pulmonary fibrosis. There is no recommended treatment for patients whose respiratory condition continues to deteriorate in spite of antigen avoidance. Whether rituximab may be beneficial to patients with cHP is unknown. The ai...

journal_title：Respiratory medicine

authors： Ferreira M,Borie R,Crestani B,Rigaud P,Wemeau L,Israel-Biet D,Leroy S,Quétant S,Plantier L,Dalphin JC,Cottin V,Marchand-Adam S,of the OrphaLung network.

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the cost-utility of the treatment with a long acting beta-agonist (LABA) and inhaled corticosteroid (ICS) combination inhaler [salmeterol xinafoate (SAL)/fluticasone propionate (FP) combination inhaler (SFC) (Advair(®))] to continuing on current ICS dose (no ICS dose change) or increased ICS dose ...

journal_title：Respiratory medicine

authors： Ismaila AS,Risebrough N,Li C,Corriveau D,Hawkins N,FitzGerald JM,Su Z

更新日期：2014-09-01 00:00:00

abstract：:Exposure to mushroom spores may cause many respiratory allergic diseases, however, there has been no serial study in a mushroom factory to address this problem. The aim of this study was to investigate the serial changes in respiratory allergy and the incidence of hypersensitivity pneumonitis (HP) in mushroom workers....

journal_title：Respiratory medicine

authors： Tanaka H,Saikai T,Sugawara H,Tsunematsu K,Takeya I,Koba H,Matsuura A,Imai K,Abe S

更新日期：2001-12-01 00:00:00

abstract：:The oxygen cost diagram (OCD) is a simple scale for quantifying a patient's evaluation of his tolerance to exercise frequently used in clinical trials; it has been shown to be well correlated with objective measures of capacity of ambulation such as the 6 min walk test (6' W). This study aimed to determine whether the...

journal_title：Respiratory medicine

authors： Janssens JP,Breitenstein E,Rochat T,Fitting JW

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Bacteria expressing phosphorylcholine (ChoP) co-opt host-expressed platelet-activating factor receptor (PAFR) to adhere to lower airway cells. Cigarette smoke and rhinovirus (RV) infection upregulate PAFR-dependent bacterial adhesion to airway cells in vitro, and in healthy adults smoking increases the propo...

journal_title：Respiratory medicine

authors： Suri R,Mallia P,Martin JE,Footitt J,Zhu J,Trujillo-Torralbo MB,Johnston SL,Grigg J

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Although respiratory muscle weakness (RMW) is known to predict prognosis in patients with heart failure with reduced ejection fraction (HFrEF), RMW prevalence and its prognosis in those with preserved ejection fraction (HFpEF) remain unknown. We aimed to investigate whether the RMW predicted mortality in HFp...

journal_title：Respiratory medicine

authors： Hamazaki N,Kamiya K,Matsuzawa R,Nozaki K,Ichikawa T,Tanaka S,Nakamura T,Yamashita M,Maekawa E,Noda C,Yamaoka-Tojo M,Matsunaga A,Masuda T,Ako J

更新日期：2020-01-01 00:00:00

abstract：:This retrospective study was designed to evaluate the safety and efficacy of a bronchoprotective sputum induction protocol in moderate to severe chronic obstructive pulmonary disease (COPD). Forty-two adults with COPD (FEV1 = 51.7 +/- 3.2% predicted (mean +/- SEM)) under went sputum induction using a protocol designed...

journal_title：Respiratory medicine

authors： Sutherland ER,Pak J,Langmack EL,Silkoff PE,Martin RJ

更新日期：2002-07-01 00:00:00

abstract：:Healthcare payers are faced with the need to allocate finite resources to maximize population health. To assist in decision-making, healthcare payers are increasingly using health outcomes information and economic analyses. Healthcare payers are often under pressure to make early decisions (around the time of product ...

journal_title：Respiratory medicine

authors： Levine M,Taylor R,Ryan M,Sculpher M

更新日期：2002-08-01 00:00:00

abstract：RATIONALE:The development of chronic obstructive pulmonary disease (COPD) in smokers and their susceptibility to infections is not fully understood. Recent evidences suggest that Clara cells play a part in host defense, immunomodulatory response and airways remodelling through the production of specific factors such as...

journal_title：Respiratory medicine

authors： Braido F,Riccio AM,Guerra L,Gamalero C,Zolezzi A,Tarantini F,De Giovanni B,Folli C,Descalzi D,Canonica GW

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:The prevalence of depression in stable COPD patients varies markedly, possibly because of use of different scales. We aimed to assess depression using 2 different depression scales and to examine the association between depression and poor exercise performance, BODE index and muscle wasting in clinically sta...

journal_title：Respiratory medicine

authors： Al-shair K,Dockry R,Mallia-Milanes B,Kolsum U,Singh D,Vestbo J

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Patients with Chronic Obstructive Pulmonary Disease with chronic respiratory failure (COPD-CRF) experience high mortality and healthcare utilization. Non-invasive home ventilation (NIVH) is increasingly used in such patients. We examined the associations between NIVH and survival, hospitalizations, and emerg...

journal_title：Respiratory medicine

authors： Frazier WD,Murphy R,van Eijndhoven E

更新日期：2020-12-30 00:00:00

abstract：BACKGROUND:Non-invasive ventilation (NIV) is increasingly used in the treatment of patients with chronic hypercapnic respiratory failure (CRF). Residual sleep related respiratory events under NIV such as obstructive or central apnea/hypopnea (AH), or patient-ventilator asynchrony (PVA), may compromise treatment efficac...

journal_title：Respiratory medicine

authors： Aarrestad S,Qvarfort M,Kleiven AL,Tollefsen E,Skjønsberg OH,Janssens JP

更新日期：2017-11-01 00:00:00

abstract：:Epithelioid haemangioendothelioma of the pulmonary vessels is a rare neoplasm which usually has a minimal clinical expression. The present case report describes an exceptional case with severe inaugural alveolar haemorrhage which led to death by acute respiratory failure within a few weeks. ...

journal_title：Respiratory medicine

authors： Briens E,Caulet-Maugendre S,Desrues B,Quinquenel ML,Lena H,Turlin B,Delaval P

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:There is wide variation in the techniques deployed to diagnose tuberculosis in the UK, with little agreement on which tools or strategies are cost effective. This analysis therefore comprehensively evaluated the cost effectiveness of currently available diagnostic strategies for routine diagnosis of TB in th...

journal_title：Respiratory medicine

authors： Hughes R,Wonderling D,Li B,Higgins B

更新日期：2012-02-01 00:00:00

abstract：INTRODUCTION:Dental caries and respiratory tract infections are among the most common infectious diseases worldwide and they both are appearing in the respiratory system. However, their relations are still unclear. This study investigated the association of dental caries on the risk of lower respiratory tract infection...

journal_title：Respiratory medicine

authors： Mehtonen IT,Rantala AK,Hugg TT,Jaakkola MS,Jaakkola JJK

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Bleach is widely used for household cleaning. Although it is recognized that occupational use of bleach may have adverse respiratory health effects, it is unknown whether common domestic use of bleach may be a risk factor for asthma. AIM:To assess whether the domestic use of bleach for home cleaning is asso...

journal_title：Respiratory medicine

authors： Matulonga B,Rava M,Siroux V,Bernard A,Dumas O,Pin I,Zock JP,Nadif R,Leynaert B,Le Moual N

更新日期：2016-08-01 00:00:00

abstract：:In the Department of Respiratory Medicine, North Staffordshire Hospital, patients fulfilling the Department of Health criteria for long-term oxygen therapy (LTOT) attend a practical teaching session on the use of their oxygen concentrator before commencing therapy. In the present study, we have audited the prescribing...

journal_title：Respiratory medicine

authors： Peckham DG,McGibbon K,Tonkinson J,Plimbley G,Pantin C

更新日期：1998-10-01 00:00:00

abstract：INTRODUCTION:Non-invasive positive pressure ventilation (NIPPV) is an effective treatment in respiratory failure. Continuous positive pressure (CPAP) may also be useful in acute hypoxaemic patients. Supplementary oxygen is usually necessary in both systems. However, the inspired oxygen fraction (FiO2) delivered by a NI...

journal_title：Respiratory medicine

authors： Samolski D,Antón A,Güell R,Sanz F,Giner J,Casan P

更新日期：2006-09-01 00:00:00

abstract：:Bird fancier's lung, the most common form of extrinsic allergic alveolitis in Britain, can be a difficult diagnostic problem. The symptoms are non-specific, often insidious in onset and frequently misdiagnosed as influenza or a viral or bacterial pneumonia. Frequently there is a delay in eliciting the history of expos...

journal_title：Respiratory medicine

authors： Vincent JM,Flower CD,Shneerson JM,Stewart S

更新日期：1992-03-01 00:00:00

abstract：:In this study we aimed to estimate direct medical costs of Chronic Obstructive Pulmonary Disease (COPD) by disease type; chronic bronchitis and emphysema. This study estimates direct costs in 1996 dollars using a prevalence approach and both aggregate and microcosting. A societal perspective is taken using prevalence,...

journal_title：Respiratory medicine

authors： Wilson L,Devine EB,So K

更新日期：2000-03-01 00:00:00

abstract：:It has been previously shown that antibiotics given before hospitalization significantly reduce the proportion of positive blood cultures in community-acquired pneumonia (CAP). The aim of this prospective study was to compare the utility and cost-benefits of blood cultures in patients, hospitalized for moderate CAP, w...

journal_title：Respiratory medicine

authors： Glerant JC,Hellmuth D,Schmit JL,Ducroix JP,Jounieaux V

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Many patients with DMD undergo tracheostomy. Tracheostomy is associated with certain complications, however its effect on prognosis is not known. METHODS:The relationship between type of mechanical ventilation and survival at 12 years was evaluated in a prospective cohort of patients with Duchenne muscular ...

journal_title：Respiratory medicine

authors： Boussaïd G,Lofaso F,Santos DB,Vaugier I,Pottier S,Prigent H,Bahrami S,Orlikowski D

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:Combination inhaled corticosteroid/long-acting bronchodilator (ICS/LABA) therapy reduces the exacerbation rate and improves spirometry and quality of life in COPD. We hypothesized that ICS/LABA therapy also improves small airway function measured by FOT. METHODS:14 subjects with COPD were commenced on com...

journal_title：Respiratory medicine

authors： Timmins SC,Diba C,Schoeffel RE,Salome CM,King GG,Thamrin C

更新日期：2014-02-01 00:00:00

abstract：:The purpose of this study was to explore respiratory health effects of indoor exposures to aldehydes and volatile organic compounds (VOCs) in elderly living in a population-based representative sample of French dwellings and to compare them to the rest of the occupants of the dwellings. Twenty VOCs were objectively me...

journal_title：Respiratory medicine

authors： Bentayeb M,Billionnet C,Baiz N,Derbez M,Kirchner S,Annesi-Maesano I

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:The aim was to investigate temporal variation in Health-Related Quality of Life (HRQL) and factors influencing low HRQL, in patients with asthma. MATERIAL AND METHODS:Questionnaire data on patient characteristics and the mini-Asthma Quality of Life Questionnaire (mini-AQLQ) scores from two separate cohort...

journal_title：Respiratory medicine

authors： Sundh J,Wireklint P,Hasselgren M,Montgomery S,Ställberg B,Lisspers K,Janson C

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Asthma in the elderly as well as asthma of adult-onset has been associated with increased morbidity, but little is known specifically about the effects of age on clinical and inflammatory outcomes in severe refractory asthma. The aims of the study were to examine the effects of age [<65 versus ≥65 years] and...

journal_title：Respiratory medicine

authors： Chaudhuri R,McSharry C,Heaney LG,Niven R,Brightling CE,Menzies-Gow AN,Bucknall C,Mansur AH,Lee W,Shepherd M,Spears M,Cowan DC,Husi H,Thomson NC,BTS Severe Asthma Network.

更新日期：2016-09-01 00:00:00

abstract：:The records of a total of 497 patients notified to have active tuberculosis (TB) in Western Australia from 1986 to 1990 inclusive have been reviewed in relation to case-finding. Of these, 276 (55.5%) were Asian migrants, 92 (18.5%) Europeans and 110 (22.1%) Australians. The disease was confirmed bacteriologically in 2...

journal_title：Respiratory medicine

authors： Pang SC,Harrison RH,Clayton AS,Mercer J,Brearley J

更新日期：1994-03-01 00:00:00

abstract：STUDY OBJECTIVES:Penicillin resistance has been reported in various studies to have no impact on the outcome of pneumococcal pneumonia. However, the importance of cephalosporin resistance has not been systematically studied. We conducted an analysis of patients with high-level cephalosporin-resistant Streptococcus pneu...

journal_title：Respiratory medicine

authors： Ailani RK,Alimchandani A,Hidalgo J,Ailani R,Buckley J,DiGiovine B

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Breathing-retraining and helium-oxygen (heliox) have been used to improve exercise tolerance in COPD. We hypothesized that, in patients with COPD, exercise duration after exercise-training plus breathing-retraining and oxygen would be longer than after exercise-training plus heliox or after exercise-training...

journal_title：Respiratory medicine

authors： Collins EG,Jelinek C,O'Connell S,Butler J,McBurney C,Gozali C,Reda D,Laghi F

更新日期：2014-02-01 00:00:00