Cephalosporin-resistant pneumococcal pneumonia: does it, affect outcome?

abstract：BACKGROUND:Systemic inflammation is associated with impaired lung function in healthy adults as well as in patients with lung disease. The mechanism for this association is unknown and it is unclear if systemic inflammation leads to impaired lung function or if poor lung function leads to inflammation. We explored the ...

journal_title：Respiratory medicine

authors： Hancox RJ,Gray AR,Sears MR,Poulton R

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:For patients with idiopathic pulmonary fibrosis (IPF), there is limited real-world data on patient journey and treatment patterns. AIM:To explore predictors of early diagnosis and treatment initiation, and treatment patterns in IPF patients using linked data from Swedish registers and electronic medical rec...

journal_title：Respiratory medicine

authors： Sköld CM,Arnheim-Dahlström L,Bartley K,Janson C,Kirchgaessler KU,Levine A,Ferrara G

更新日期：2019-08-01 00:00:00

abstract：:Capsaicin has long been known to act selectively on a subpopulation of neurons to produce initial excitation, followed by a prolonged neuroinhibitory action commonly referred to as 'capsaicin desensitization'. This property has been exploited extensively as a tool with which to investigate the role of these nerves in ...

journal_title：Respiratory medicine

authors： O'Neill TP

更新日期：1991-01-01 00:00:00

abstract：INTRODUCTION:Dental caries and respiratory tract infections are among the most common infectious diseases worldwide and they both are appearing in the respiratory system. However, their relations are still unclear. This study investigated the association of dental caries on the risk of lower respiratory tract infection...

journal_title：Respiratory medicine

authors： Mehtonen IT,Rantala AK,Hugg TT,Jaakkola MS,Jaakkola JJK

更新日期：2019-01-01 00:00:00

abstract：RATIONALE:Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing interstitial pneumonia. The pathogenicity of IPF has been widely investigated but still remains to be clarified. Efferocytosis, the specialized recognition and ingestion of apoptotic cells by phagocytes, is essential for the resolution of...

journal_title：Respiratory medicine

authors： Morimoto K,Janssen WJ,Terada M

更新日期：2012-12-01 00:00:00

abstract：:Citric acid has been used as a tussive agent in the investigation of the cough reflex. The mechanism of cough stimulation remains unclear. We conducted studies to compare the cough response of citric acid to an organic (acetic acid) and an inorganic acid (phosphoric acid). We also compared the cough response of citric...

journal_title：Respiratory medicine

authors： Wong CH,Matai R,Morice AH

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Breathing-retraining and helium-oxygen (heliox) have been used to improve exercise tolerance in COPD. We hypothesized that, in patients with COPD, exercise duration after exercise-training plus breathing-retraining and oxygen would be longer than after exercise-training plus heliox or after exercise-training...

journal_title：Respiratory medicine

authors： Collins EG,Jelinek C,O'Connell S,Butler J,McBurney C,Gozali C,Reda D,Laghi F

更新日期：2014-02-01 00:00:00

abstract：:In a double-blind study of 60 patients undergoing fibreoptic bronchoscopy we have compared the local anaesthetic effects of intratracheal injections of cocaine (4 ml, 2.5%) and lignocaine (4 ml, 4%). The two local anaesthetics were equally effective in terms of cough suppression, requirement for extra local anaestheti...

journal_title：Respiratory medicine

authors： Teale C,Gomes PJ,Muers MF,Pearson SB

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:It has been reported that adverse fetal outcomes are more prevalent in pregnant women with asthma than they are in women without asthma. In our study, we investigated the effect that the severity of asthma during pregnancy has on the risk of a small for gestational age (SGA) infant, low birth weig...

journal_title：Respiratory medicine

authors： Firoozi F,Lemière C,Ducharme FM,Beauchesne MF,Perreault S,Bérard A,Ferreira E,Forget A,Blais L

更新日期：2010-09-01 00:00:00

abstract：:The aim of this study was to examine an acoustic reflection method using a flexible tube for identifying the obstructive site of the upper airway in snorers and patients with obstructive sleep apnoea (OSA). As a preliminary study it was performed n models and subjects in the awake state. Flextube narrowing was produce...

journal_title：Respiratory medicine

authors： Faber CE,Grymer L,Norregaard O,Hilberg O

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:A predominant feature of asthma is an accelerated rate of decline in forced expiratory volume in 1 s (FEV1), but data on the variability and factors associated with this change in patients with controlled asthma are largely unknown. METHODS:140 patients with controlled asthma were enrolled based on the Glob...

journal_title：Respiratory medicine

authors： Matsunaga K,Ichikawa T,Oka A,Morishita Y,Kanai K,Hiramatsu M,Akamatsu H,Kawabata H,Kikuchi T,Akamatsu K,Hirano T,Kou Y,Nakanishi M,Minakata Y,Yamamoto N

更新日期：2014-07-01 00:00:00

abstract：:The objective of this study was to evaluate the effect of lateral body position on gas exchange in patients with unilateral pleural effusion, with special reference to the influence of effusion volume. Thirty consecutive patients with unilateral pleural effusion, without evidence of parenchymal pulmonary involvement, ...

journal_title：Respiratory medicine

authors： Romero S,Martín C,Hernández L,Arriero JM,Benito N,Gil J

更新日期：1995-04-01 00:00:00

abstract：:Seventy-seven patients with morbid obesity, body mass index (BMI) 40-69.9 kg m(-2), who were candidates for gastroplasty, were studied in our laboratory as part of a pre-operative survey. They had no complaints other than obesity and were not cyanotic. A group of 28 lean subjects (BMI 20-29.8 kg m(-2)) who were candid...

journal_title：Respiratory medicine

authors： Ladosky W,Botelho MA,Albuquerque JP Jr

更新日期：2001-04-01 00:00:00

abstract：:The sick building syndrome has been the subject of research for approximately 10 years. Although it is often suggested that symptoms in office workers are due to circulating micro-organisms or particles, epidemiological studies investigating the relationship between them have been lacking. This cross-sectional study h...

journal_title：Respiratory medicine

authors： Harrison J,Pickering CA,Faragher EB,Austwick PK,Little SA,Lawton L

更新日期：1992-05-01 00:00:00

abstract：:Asthma is a very common respiratory disease which is characterized by the presence of cytokine-mediated airway inflammation leading to smooth muscle contraction, oedema and progressive airway damage in some cases. In light of our recent finding of an increased sero-prevalence of Helicobacter pylori in bronchiectasis, ...

journal_title：Respiratory medicine

authors： Tsang KW,Lam WK,Chan KN,Hu W,Wu A,Kwok E,Zheng L,Wong BC,Lam SK

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The 6 min walk test (6MWT) provides prognostic information in various respiratory diseases, but limited data exist in cystic fibrosis (CF) adults. METHODS:Consecutive CF adults who performed 6MWT at Cochin Hospital (Paris, France) over 12 years were analyzed. The cut-off 6 min walking distance (6MWD) value ...

journal_title：Respiratory medicine

authors： Martin C,Chapron J,Hubert D,Kanaan R,Honoré I,Paillasseur JL,Aubourg F,Dinh-Xuan AT,Dusser D,Fajac I,Burgel PR

更新日期：2013-12-01 00:00:00

abstract：:The aims of this study were to describe asthma management and morbidity in patients attending general practitioners in Australia, and to assess the relationship between patient reports and those of their general practitioner (GP). The sample comprised consecutive patients attending 46 general practitioners chosen at r...

journal_title：Respiratory medicine

authors： Bauman A,Cooper C,Bridges-Webb C,Tse M,Miles D,Bhasale A,Pollock M

更新日期：1995-11-01 00:00:00

abstract：:Asthma progression is associated with airway remodeling and neo-vascularization. However, role of angiogenesis in these changes remains unclear and available data still incomplete. In this pilot study we verify usefulness of proteome profiler assay in screening of angiogenesis-related factors in exhaled breath condens...

journal_title：Respiratory medicine

authors： Grzela K,Litwiniuk M,Krejner A,Zagorska W,Grzela T

更新日期：2016-09-01 00:00:00

abstract：:Collection of airway calibre and beta2-agonist data in large clinical trials and epidemiological surveys is sometimes difficult and may be an inefficient use of resources. The aim of this study was to determine whether the omission of the forced expiratory volume in 1 sec (FEV1) and beta2-agonist questions from the se...

journal_title：Respiratory medicine

authors： Juniper EF,O'Byrne PM,Roberts JN

更新日期：2001-05-01 00:00:00

abstract：:The fine particle dose delivered via dry powder inhalers (DPIs) is often affected by the inspiratory flow rate generated during inhalation. This has clinical implications, since the fine particle dose determines the amount of drug reaching the lungs. With Easyhaler DPI the fine particle dose remains relatively constan...

journal_title：Respiratory medicine

authors： Koskela T,Malmström K,Sairanen U,Peltola S,Keski-Karhu J,Silvasti M

更新日期：2000-12-01 00:00:00

abstract：INTRODUCTION:Brit-Hogg-Dubé syndrome (BHD) is a rare disorder that is estimated to affects about 600 families in the World. The disease-causing mutations is on FLCN gene which codes for folliculin. This protein has a role in different organs as skin, kidney and lung, thanks to the interaction with type I and II cadheri...

journal_title：Respiratory medicine

authors： Marziali V,Geropoulos G,Frasca L,Longo F,Patrini D,Panagiotopoulos N,Crucitti P

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Current and former smokers with normal spirometry and with Preserved Ratio Impaired Spirometry (PRISm) experience respiratory events similar to chronic obstructive pulmonary disease (COPD) exacerbations. Exacerbations significantly reduce quality of life (QoL) in COPD patients however the effect of respira...

journal_title：Respiratory medicine

authors： Parekh TM,Bhatia S,Cherrington A,Kim YI,Lambert A,Iyer A,Regan EA,DeMeo DL,Han M,Dransfield MT

更新日期：2020-01-01 00:00:00

abstract：:Eighteen patients with community acquired pneumonia required intensive care for severe or progressive hypoxaemia, rising arterial carbon dioxide tension or respiratory arrest, and 17 received intermittent positive pressure ventilation. Thirteen survived to leave hospital and 12 are long term survivors. Ventilation was...

journal_title：Respiratory medicine

authors： Alkhayer M,Jenkins PF,Harrison BD

更新日期：1990-01-01 00:00:00

abstract：:Inhalation of organic dust from a swine-confinement building leads to an intense inflammatory reaction with an increased number of inflammatory cells and mediators in the upper and lower respiratory tract of previously unexposed subjects. In vitro the dust induces cytokine release from epithelial cells and alveolar ma...

journal_title：Respiratory medicine

authors： Burvall K,Palmberg L,Larsson K

更新日期：2003-01-01 00:00:00

abstract：:In recent years, it has become increasingly important to get as much as possible information on clinical efficacy already in the early phases of drug development. For proof of concept (POC) studies testing novel anti-inflammatory drugs in asthma, there are several validated exacerbation models, inducing various aspect...

journal_title：Respiratory medicine

authors： Diamant Z,Boot D,Kamerling I,Bjermer L

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Physical activity and health status deteriorate early in the course of chronic obstructive pulmonary disease (COPD). This can only partially be explained by the degree of airflow limitation. Changes in (resting and dynamic) lung volumes are known to be associated with functional impairments and thus might in...

journal_title：Respiratory medicine

authors： Lahaije AJ,van Helvoort HA,Dekhuijzen PN,Vercoulen JH,Heijdra YF

更新日期：2013-06-01 00:00:00

abstract：:We studied tuberculin reactivity in young Norwegian adults and its possible dependency on age, gender, previous BCG vaccination, smoking habits, occupational exposure, diet as well as years of education as a measure of socio-economic status. Responders of a random sample of men and women aged 20-44 years living in Ber...

journal_title：Respiratory medicine

authors： Jentoft HF,Omenaas E,Eide GE,Gulsvik A

更新日期：2002-12-01 00:00:00

abstract：:This manuscript offers an approach to the treatment of pulmonary sarcoidosis based on current available information. The treatment of pulmonary sarcoidosis is not mandatory as the disease may be self-limiting and therapy is often associated with significant drug side effects. The decision to treat rests predominantly ...

journal_title：Respiratory medicine

authors： Judson MA

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Bronchiectasis (BQs) is an uncommon disease with the potential to cause devastating complications. All patients with BQs have cough and chronic sputum production that may have a great impact on patient's quality of life. Upper airway symptoms are also frequent in patients with BQs. Associations between upper...

journal_title：Respiratory medicine

authors： Guilemany JM,Alobid I,Angrill J,Ballesteros F,Bernal-Sprekelsen M,Picado C,Mullol J

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:To assess the utility of capsaicin test in the differential diagnosis of non-productive causes of chronic cough and to examine the effects of treatment on this reflex. PARTICIPANTS:86 healthy volunteers and 101 patients with chronic cough: asthma (n: 54) gastroesophageal reflux (n: 35) and post-nasal drip s...

journal_title：Respiratory medicine

authors： Nieto L,de Diego A,Perpiñá M,Compte L,Garrigues V,Martínez E,Ponce J

更新日期：2003-04-01 00:00:00