Abstract：
:We studied tuberculin reactivity in young Norwegian adults and its possible dependency on age, gender, previous BCG vaccination, smoking habits, occupational exposure, diet as well as years of education as a measure of socio-economic status. Responders of a random sample of men and women aged 20-44 years living in Bergen, Norway were interviewed and tested withthe adrenaline-Pirquettest with Norwegian-produced synthetic mediumtuberculin at the out-patient chest clinic in the city of Bergen in 1992-1993. Nine hundred and three subjects out of 1200 met for the clinical examination (75%). Five hundred and eighty-eight subjects were tuberculin-tested and read, whereof 95% were BCG vaccinated by age 14. Mean tuberculin reactivity was 4.8 mm (SD: 3.0 mm). A positive reaction (> or = 4 mm) was found in 64%, whereof 7% had a strongly positive reaction (>10 mm). A negative reaction (<4 mm) occurred in 36%, whereof 10% had no reaction (0 mm). Only 30% ofthe females and 36% of the males aged 21--25 years were tuberculin positive 7-12 years after BCG vaccination. Linear regression analysis demonstrated tuberculin reactivity to increase with increasing age, male gender with an increasing sex effect by age, and current smoking. Occupational dust or gas exposure, a diet rich in vitamin C or years of education did not influence tuberculin reactivity significantly.
journal_name
Respir Medjournal_title
Respiratory medicineauthors
Jentoft HF,Omenaas E,Eide GE,Gulsvik Adoi
10.1053/rmed.2002.1386subject
Has Abstractpub_date
2002-12-01 00:00:00pages
1033-9issue
12eissn
0954-6111issn
1532-3064pii
S0954-6111(02)91386-7journal_volume
96pub_type
杂志文章abstract：:Cyclosporin A (CsA) is an immunomodulator drug that has been used in the treatment of several types of advanced pulmonary interstitial disease. This beneficial effect occurs mainly in circumstances in which alveolitis due to CD4 lymphocytes is absent, suggesting that CsA acts on other types of cells. The present study...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/s0954-6111(98)90002-6
更新日期：1998-05-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:It has been reported that adverse fetal outcomes are more prevalent in pregnant women with asthma than they are in women without asthma. In our study, we investigated the effect that the severity of asthma during pregnancy has on the risk of a small for gestational age (SGA) infant, low birth weig...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2010.03.010
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:During military service young men (age 19-21 years) are exposed to many predisposing factors for asthma. We aimed to study the short-term prognosis of asthma after the military service. METHODS:All 216 men with verified asthma in 2004-2005 from the register of the Central Military Hospital were included in ...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2009.05.022
更新日期：2009-12-01 00:00:00
abstract：:Pneumocystis carinii colonization was studied in 90 men using the polymerase chain reaction. These comprised ten heterosexual controls; ten HIV-seronegative homosexual controls; 20 HIV-seropositive homosexuals with blood CD4 count > 400 x 10(6) l-1; 20 HIV-seropositive homosexuals with CD4 < 400 x 10(6) l-1; ten HIV-s...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/0954-6111(93)90008-n
更新日期：1993-10-01 00:00:00
abstract：BACKGROUND:Systemic inflammation is associated with impaired lung function in healthy adults as well as in patients with lung disease. The mechanism for this association is unknown and it is unclear if systemic inflammation leads to impaired lung function or if poor lung function leads to inflammation. We explored the ...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2015.12.007
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:There are chronic forms of hypersensitivity pneumonitis (cHP) that can progress to pulmonary fibrosis. There is no recommended treatment for patients whose respiratory condition continues to deteriorate in spite of antigen avoidance. Whether rituximab may be beneficial to patients with cHP is unknown. The ai...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2020.106146
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Alpha-1-antitrypsin deficiency (AATD) is significantly underdiagnosed. The early detection of AATD would enable affected persons to make lifestyle changes such as quitting smoking. It was the aim of the study to determine whether the combination of an awareness program with the offer of a cost-free diagnosti...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2007.02.024
更新日期：2007-08-01 00:00:00
abstract：:Lactose is widely used as a carrier of drugs in inhalation devices for asthmatic patients, but some clinicans have suspected that it may cause bronchoconstriction. Only a few studies have been done to examine this and the results are not uniform. This study was conducted to determine the effects of inhalation grade la...
journal_title：Respiratory medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1053/rmed.2001.1150
更新日期：2001-11-01 00:00:00
abstract：BACKGROUND:Previous investigations have suggested that genetic variations are associated with reduced lung function in early childhood. This study was conducted to evaluate the association between IL13+2044G-->A, the functionally relevant single nucleotide polymorphism (SNP) in the gene coding IL13, and lung function i...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2008.08.009
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:Trends in prevalence of asthma and allergic diseases are still controversial, and rarely studied among adolescents at midpoint of puberty. METHODS:In 2000, a questionnaire was mailed to adolescents (n = 18,158) attending 9th grade at school and living in Västra Götaland County, Sweden. Eight years later, th...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2014.02.011
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:Primary spontaneous pneumothorax (PSP) remains a significant global health problem. Despite general agreement, an official algorithm for the management of PSP still does not exist. OBJECTIVES:Evaluating the efficacy of all available treatments in PSP. METHODS:A systematic search of 12 electronic databases ...
journal_title：Respiratory medicine
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.rmed.2018.03.009
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Discrepancies have been observed between clinical, physiological, and inflammatory asthma control criteria, mostly in asthmatic subjects using regular inhaled corticosteroids (ICS) treatment. This study compared the prevalence of discrepancies between these 3 control parameters in mild asthmatic subjects not...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2012.12.015
更新日期：2013-04-01 00:00:00
abstract：INTRODUCTION:Subjective fatigue has been recognised as an important, multi-component symptom in COPD. Pulmonary Rehabilitation (PR) improves fatigue component of the Chronic Respiratory Questionnaire, a quality of life (QoL) measure. However, it is not clear if all fatigue dimensions are affected equally. This study ai...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2013.09.003
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:The 6 min walk test (6MWT) provides prognostic information in various respiratory diseases, but limited data exist in cystic fibrosis (CF) adults. METHODS:Consecutive CF adults who performed 6MWT at Cochin Hospital (Paris, France) over 12 years were analyzed. The cut-off 6 min walking distance (6MWD) value ...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2013.10.001
更新日期：2013-12-01 00:00:00
abstract：:The oxygen cost diagram (OCD) is a simple scale for quantifying a patient's evaluation of his tolerance to exercise frequently used in clinical trials; it has been shown to be well correlated with objective measures of capacity of ambulation such as the 6 min walk test (6' W). This study aimed to determine whether the...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/s0954-6111(99)90266-4
更新日期：1999-11-01 00:00:00
abstract：:The pathophysiology of corticosteroid-induced osteoporosis is complex, but centres around a primary inhibition of osteoblastic activity compounded by the effects of secondary hyperparathyroidism. The preservation of the microanatomy of bone in the early stages of the disease, coupled with strategies to prevent the eme...
journal_title：Respiratory medicine
pub_type： 杂志文章,评审
doi：10.1016/s0954-6111(05)80252-5
更新日期：1993-02-01 00:00:00
abstract：:Despite the growing field of interest in the role of pulmonary oxidative stress in chronic obstructive pulmonary disease (COPD), barely any data are available with respect to antioxidant capacity in the peripheral musculature of these patients. The main objective of this study was to assess in detail the antioxidant s...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2004.05.018
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:Interstitial lung disease (ILD) is a common extramuscular manifestation of the idiopathic inflammatory myopathies (IIMs), dermatomyositis (DM) and polymyositis (PM). Patients with antisynthetase antibodies (ASA) demonstrate some or all of the features of the antisynthetase syndrome including IIM and ILD. It ...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2014.09.003
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Poor mask fit and mouth leak are associated with nasal symptoms and poor sleep quality in patients receiving domiciliary non-invasive ventilation (NIV) through a nasal mask. Normal subjects receiving continuous positive airways pressure demonstrate increased nasal resistance following periods of mouth leak. ...
journal_title：Respiratory medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.rmed.2007.05.005
更新日期：2007-09-01 00:00:00
abstract：:The principals of rehabilitation medicine are to prevent muscle atrophy and improve mobility. Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with muscle atrophy and yet many patients do not undergo pulmonary rehabilitation until they have been in stable health for some time. We investigat...
journal_title：Respiratory medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.rmed.2005.02.033
更新日期：2005-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Mycobacterium tuberculosis has been proposed as a candidate agent for the cause of sarcoidosis. The QuantiFERON-TB Gold test has a higher specificity for detecting M. tuberculosis infection than the conventional tuberculin skin test. This study aimed to investigate the rate of positive QuantiFE...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2007.09.013
更新日期：2008-02-01 00:00:00
abstract：:The aim of this study was to compare the efficacy and safety of salmeterol/fluticasone propionate combination product (SFC) with fluticasone propionate (FP) plus oral montelukast (M) over 12 weeks in symptomatic asthma patients. The study was a multinational, randomised, double-blind, double-dummy, parallel-group desi...
journal_title：Respiratory medicine
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1053/rmed.2003.1436
更新日期：2003-03-01 00:00:00
abstract：BACKGROUND:Asthma is a common chronic disease in childhood, resulting in high costs for health care systems and society. As of June 2011, the Brazilian Unified Health System (SUS) provides free asthma medications for the population. This study evaluated the impact of this program on asthma admissions in the population ...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2020.105915
更新日期：2020-04-01 00:00:00
abstract：:The efficacy of a non-steroidal anti-inflammatory agent (nedocromil sodium, NS) has been assessed in young children born prematurely who had recurrent respiratory symptoms at follow-up. In a randomized, double-blind cross-over trial, either two puffs of NS (2 mg puff-1) or placebo were administered three times a day v...
journal_title：Respiratory medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0954-6111(96)90173-0
更新日期：1996-09-01 00:00:00
abstract：:It has been previously shown that antibiotics given before hospitalization significantly reduce the proportion of positive blood cultures in community-acquired pneumonia (CAP). The aim of this prospective study was to compare the utility and cost-benefits of blood cultures in patients, hospitalized for moderate CAP, w...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/s0954-6111(99)90010-0
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:Selection of heath-related quality of life (HRQL) instruments that are most responsive to changes in HRQL prevents investigators from drawing false-negative conclusions about the effectiveness of an intervention. The objective of this study was to compare the responsiveness of the Chronic Respiratory Questio...
journal_title：Respiratory medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.rmed.2006.04.023
更新日期：2007-02-01 00:00:00
abstract：:Total lung capacity was measured in 16 workers with pulmonary asbestosis using four standard methods: body plethysmography, radiographic lung area, helium dilution by multiple breath and by single breath (alveolar volume). All men had irregular opacities of ILO profusion category 2/1 or greater and four had pleural pl...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/0954-6111(93)90138-p
更新日期：1993-02-01 00:00:00
abstract：BACKGROUND:Nitrite in exhaled breath condensate (EBC) has been shown to be elevated in cystic fibrosis (CF), while exhaled nitric oxide (FENO) is paradoxically low. This has been argued to reflect increased metabolism of NO while its diffusion is obstructed by mucus. However, we wanted to study the possible influence o...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2008.09.009
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:IL-4 receptor alpha chain is crucial for the binding and signaling of IL-4, which mediates isotype switching and IgE production. The gene of IL-4 receptor alpha chain is a candidate gene for asthma and atopy. OBJECTIVES:To determine whether Ile50Val and Q576R polymorphisms of IL-4 receptor alpha chain gene ...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2006.04.004
更新日期：2007-01-01 00:00:00
abstract：BACKGOUND AND OBJECTIVES:The disadvantages of custom-made mandibular advancement devices (MAD) for obstructive sleep apnoea (OSA) therapy are the cost and delay required to manufacture the device. This study aimed to evaluate the efficacy of a titrable, thermoplastic MAD compared to a custom-made MAD for OSA therapy. ...
journal_title：Respiratory medicine
pub_type： 临床试验,杂志文章
doi：10.1016/j.rmed.2017.08.004
更新日期：2017-10-01 00:00:00
