Abstract:
INTRODUCTION:Dental caries and respiratory tract infections are among the most common infectious diseases worldwide and they both are appearing in the respiratory system. However, their relations are still unclear. This study investigated the association of dental caries on the risk of lower respiratory tract infections (LRTI) in young adulthood. METHODS:The study population consisted of 1,592 Finnish young adults participating in the 20-year follow-up of The Espoo Cohort Study. The information on the occurrence of LRTIs (pneumonia or acute bronchitis) during the preceding 12 months was based on the follow-up questionnaire and the National Hospital Discharge Register. Lifelong caries on permanent teeth was defined as a self-reported number of filled teeth (FT). The risk ratios (RR) of LRTIs with 95% confidence intervals (CI) were estimated using Poisson regression models. RESULTS:High FT number was associated with an increased occurrence of LRTIs with an adjusted RR of 1.24 per interquartile range (IQR) of FT (95% CI 1.06-1.44). The risk of LRTIs increased according to the increasing number of FTs, being highest among those subjects with 10 or more filled teeth (adjusted RR 2.30; 1.27-4.17). Family's socioeconomic status or smoking did not modify the effect. CONCLUSIONS:Our results suggest that dental caries increases the risk of LRTIs. We did not find any significant effect modification by shared determinants of caries and LRTIs. However, it is possible, that common risk factors might explain at least partly the observed relation between FT and LRTIs or that the causality is bidirectional.
journal_name
Respir Medjournal_title
Respiratory medicineauthors
Mehtonen IT,Rantala AK,Hugg TT,Jaakkola MS,Jaakkola JJKdoi
10.1016/j.rmed.2019.09.002subject
Has Abstractpub_date
2019-01-01 00:00:00pages
1-5eissn
0954-6111issn
1532-3064pii
S0954-6111(19)30282-3journal_volume
158pub_type
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