Abstract:
:The metabolic thermograms and heat output of mitochondria isolated from carp liver have been determined by using an LKB bioactivity monitor. The thermogram can be divided into four parts: the lag phase, active recovery phase, stationary phase, and decline phase. The thermokinetic equation was established for the active recovery and decline phase of metabolism as follows: dP/dt = k(m)P (1-SP). The rate constants k1 and k2 of two phases of active recovery and decline phase have been also calculated. The metabolism activity of mitochondrial inhibited by a high concentration of trace element selenium has been studied. The metabolic heat released, time of each phase, and rate constants can be significantly influenced by excess of selenite added. These results suggested that a high concentration of selenium can damage the structure and function of mitochondria, and thus influence their metabolism.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Chen C,Liu Y,Zhou J,Xu H,Qu Sdoi
10.1007/BF02783314subject
Has Abstractpub_date
1997-10-01 00:00:00pages
115-22issue
1-2eissn
0163-4984issn
1559-0720journal_volume
60pub_type
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