Previous training in the water maze: differential effects in NMRI and C57BL mice.

Abstract:

:It has been shown that acquisition rates in the water maze vary across strains of mice, although the differential effects of previous experience in this spatial task have been scarcely evaluated. The aim of the present study was to evaluate the effects of training in the water maze at an early age (2 months) in two strains of mice (NMRI and C57BL) using a longitudinal study. Mice with or without previous training were tested when they were 6 months, and retested when 10 months old. The results showed that trained NMRI mice performed better than all the other groups, both at test and retest, indicating that previous training had more beneficial effects in NMRI than in C57BL mice. These results demonstrate that the effects of an early training in the water maze may be influenced by the characteristics of the strain of mice. It could have implications in longitudinal studies evaluating effects of pharmacological or behavioral manipulations.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Vicens P,Bernal MC,Carrasco MC,Redolat R

doi

10.1016/s0031-9384(99)00059-1

subject

Has Abstract

pub_date

1999-08-01 00:00:00

pages

197-203

issue

2

eissn

0031-9384

issn

1873-507X

pii

S0031-9384(99)00059-1

journal_volume

67

pub_type

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