Molecular cloning and expression of 56-58 KD antigen associated with transplant coronary artery disease.

abstract：:The neural system appears before the vascular system in the phylogenetic tree. During evolution, vascular system generation takes advantage of the pre-existing vascular endothelial growth factor (VEGF) in order to form its networks. Nevertheless, the role of VEGF in neuronal and glial cells is not yet completely under...

journal_title：Biochemical and biophysical research communications

authors： Fusco MA,Wajsenzon IJ,de Carvalho SL,da Silva RT,Einicker-Lamas M,Cavalcante LA,Allodi S

更新日期：2014-05-02 00:00:00

abstract：:Angiogenesis plays a pivotal role in gastric ulcer repair. Several growth factors are involved in angiogenesis, and of these, vascular endothelial growth factor (VEGF) has received considerable attention, since it is the only factor that specifically acts on endothelial cells. However, the role of VEGF in gastric ulce...

journal_title：Biochemical and biophysical research communications

authors： Takahashi M,Kawabe T,Ogura K,Maeda S,Mikami Y,Kaneko N,Terano A,Omata M

更新日期：1997-05-19 00:00:00

abstract：:Critical analysis of the data published so far concerning the TSG101 gene revealed some inconsistencies leading us to its re-evaluation in 80 breast, brain, colon, and neuroectodermal tumors and 37 normal tissue specimens. In this study, the occurrence of TSG101 cDNA aberrant transcripts was verified, but in addition ...

journal_title：Biochemical and biophysical research communications

authors： Hampl M,Hampl J,Plaschke J,Fitze G,Schackert G,Saeger HD,Schackert HK

更新日期：1998-07-30 00:00:00

abstract：:ICSAT (Interferon Consensus Sequence binding protein for Activated T cells) is a lymphocyte-specific member of the interferon regulatory factor (IRF) family of transcription factors, originally identified through Southwestern screening of the ATL(Adult T-cell leukemia)-16T expression library. In this study, we created...

journal_title：Biochemical and biophysical research communications

authors： Saito T,Yamagata T,Takahashi T,Honda H,Hirai H

更新日期：1999-07-05 00:00:00

abstract：:Interleukin (IL)-18 bioactivity and dsRNA sensing by receptors of innate immunity are key components of anti-viral host defense. Despite extensive data on signal transduction activated by both pathways knowledge on cross-communication is incomplete. By using human PBMC and predendritic KG1 cells, as prototypic IL-18-r...

journal_title：Biochemical and biophysical research communications

authors： Balah A,Akool el-S,Bachmann M,Pfeilschifter J,Mühl H

更新日期：2009-11-27 00:00:00

abstract：:IL-17, which exerts strong pro-inflammatory effects, has emerged as an important mediator in inflammation-associated cancer. However, the characteristics of IL-17-producing cells, the relevance of IL-17 to clinical parameters and its function in the development and progression of colorectal carcinoma still remain to b...

journal_title：Biochemical and biophysical research communications

authors： Liu J,Duan Y,Cheng X,Chen X,Xie W,Long H,Lin Z,Zhu B

更新日期：2011-04-08 00:00:00

abstract：:While recent insights indicate that the transcription factor Krüppel-like factor 4 (KLF4) is indispensable for vascular homeostasis, its exact role in proliferation and angiogenesis and how it functions remain unresolved. Thus, the aim of the present study was to evaluate the role of KLF4 in the proliferations of endo...

journal_title：Biochemical and biophysical research communications

authors： Zheng X,Li A,Zhao L,Zhou T,Shen Q,Cui Q,Qin X

更新日期：2013-08-09 00:00:00

abstract：:Anamorsin (AM) (also called CIAPIN-1) is a cell-death-defying factor. AM deficient mice die during late gestation; AM deficient embryos are anemic and very small compared to wild type (WT) embryos. It is thought that AM plays crucial roles in hematopoiesis and embryogenesis. To clarify the mechanisms of AM functions, ...

journal_title：Biochemical and biophysical research communications

authors： Saito Y,Shibayama H,Tanaka H,Tanimura A,Matsumura I,Kanakura Y

更新日期：2011-05-06 00:00:00

abstract：:The presence of a significantly increased content of free-cystine in skin fibroblasts from both homozygotes and heterozygotes for cystinosis emphasizes the central role of cystine in this disease, even though the primary defect responsible for cystine accumulation is yet to be determined. The studies described in this...

journal_title：Biochemical and biophysical research communications

authors： Schneider JA,Rosenbloom FM,Bradley KH,Seegmiller JE

更新日期：1967-11-30 00:00:00

abstract：:COOH-terminal cytoplasmic domains of G protein-coupled receptors (GPCRs) have been shown to carry determinants that control their cell surface localization, internalization, and recycling. In attempts to seek cellular proteins that mediate these processes of PTH/PTH-related protein receptor (PTHR), one of the class B ...

journal_title：Biochemical and biophysical research communications

authors： Sugai M,Saito M,Sukegawa I,Katsushima Y,Kinouchi Y,Nakahata N,Shimosegawa T,Yanagisawa T,Sukegawa J

更新日期：2003-11-07 00:00:00

abstract：:Recent evidence suggests that untimely retinoblastoma protein (RB) dephosphorylation and/or proteolytic degradation might provide key events down-stream cysteine protease (caspase) activation in apoptosis induction. We have dealt with this issue by studying apoptosis induced by N-hexanoylsphingosine (C6-Cer) in CHP-10...

journal_title：Biochemical and biophysical research communications

authors： Spinedi A,Amendola A,Di Bartolomeo S,Piacentini M

更新日期：1998-02-24 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Senescence marker protein 30 (SMP30) is assumed to behave as an anti-aging factor. Recently, we have demonstrated that deficiency of SMP30 exacerbates angiotensin II-induced cardiac hypertrophy, dysfunction and remodeling, suggesting that SMP30 may have a protective role in the heart. Thus, thi...

journal_title：Biochemical and biophysical research communications

authors： Misaka T,Suzuki S,Miyata M,Kobayashi A,Ishigami A,Shishido T,Saitoh S,Kubota I,Takeishi Y

更新日期：2013-09-13 00:00:00

abstract：:In cultures of human foreskin fibroblasts most of the cell surface binding sites for 2-chain urokinase are masked and can be exposed by 10 min. incubation on ice at pH 2.5 (A. Bajpai and J.B. Baker (1985), Biochem. Biophys. Res. Commun.133, 475-482). Here we show that incubation on ice at pH 2.5 also releases from the...

journal_title：Biochemical and biophysical research communications

authors： Bajpai A,Baker JB

更新日期：1985-12-31 00:00:00

abstract：:Severe cold exposure and pressure overload are both known to prompt oxidative stress and pathological alterations in the heart although the interplay between the two remains elusive. Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel activated in response to a variety of exogenous and en...

journal_title：Biochemical and biophysical research communications

authors： Lu S,Xu D

更新日期：2013-12-06 00:00:00

abstract：:Mitochondrial reactive oxygen species (ROS) are associated with multiple cellular functions such as cell proliferation, differentiation, and apoptosis. In particular, high levels of mitochondrial ROS in hypoxic cells regulate many angiogenesis-related diseases, including cancer and ischemic disorders. Here we report a...

journal_title：Biochemical and biophysical research communications

authors： Kim KH,Park JY,Jung HJ,Kwon HJ

更新日期：2011-01-07 00:00:00

abstract：:The trophoblast-like choriocarcinoma cell line BeWo expresses a receptor for vascular endothelial growth factor (VEGF) and proliferates in response to VEGF. Nitric oxide (NO) seems to play a key role in the VEGF-induced proliferation of endothelial cells but the NO mechanistic regulation of VEGF-stimulated trophoblast...

journal_title：Biochemical and biophysical research communications

authors： Cha MS,Lee MJ,Je GH,Kwak JY

更新日期：2001-04-13 00:00:00

abstract：:Cholesterol homeostasis is strictly maintained to prevent abnormal biological processes that arise from excessive accumulation of cholesterol in tissues. Although dyslipidemia causes reproductive dysfunction and endocrine disruption in male rats, regulatory factors and mechanisms have not been clearly demonstrated. Th...

journal_title：Biochemical and biophysical research communications

authors： Lim W,Bae H,Sohn JY,Jeong W,Kim SH,Song G

更新日期：2015-01-02 00:00:00

abstract：:Many studies have been reported that tripartite motif-containing (TRIM) proteins play important roles in various cellular processes and involved in many diseases. TRIM3, a member of TRIM family, has been proved that it plays important roles in various cancers. Nevertheless, its effects on cervical cancer reminded unkn...

journal_title：Biochemical and biophysical research communications

authors： Song Y,Guo Q,Gao S,Hua K

更新日期：2018-04-06 00:00:00

abstract：:The organic anion and cation transporters (OATs and OCTs) are a large family (SLC22) of transmembrane proteins that are able to transport a variety of compounds including drugs, environmental toxins, and endogenous metabolites. OATs are expressed in various tissues, primarily kidney and liver, but also in placenta, sm...

journal_title：Biochemical and biophysical research communications

authors： Monte JC,Nagle MA,Eraly SA,Nigam SK

更新日期：2004-10-15 00:00:00

abstract：:The α1,3/4-fucosyltransferases (FUT) subfamily are key enzymes in cell surface antigen synthesis during various biological processes. A novel role of FUTs in tumorigenesis has been discovered recently, however, the underlying mechanism remains largely unknown. Here, we characterized FUT6, a member of α1,3/4-FUT subfam...

journal_title：Biochemical and biophysical research communications

authors： Guo Q,Guo B,Wang Y,Wu J,Jiang W,Zhao S,Qiao S,Wu Y

更新日期：2012-01-06 00:00:00

abstract：:Inflammation has been implicated in a variety of psychiatric disorders. We aimed to determine whether levels of complement C5 protein in the cerebrospinal fluid (CSF), which may reflect activation of the complement system in the brain, are altered in patients with major psychiatric disorders. Additionally, we examined...

journal_title：Biochemical and biophysical research communications

authors： Ishii T,Hattori K,Miyakawa T,Watanabe K,Hidese S,Sasayama D,Ota M,Teraishi T,Hori H,Yoshida S,Nunomura A,Nakagome K,Kunugi H

更新日期：2018-03-04 00:00:00

abstract：:Molecular analysis of the induction of the lutropin/choriogonadotropin receptor during the process of luteinization of the rat ovary was performed. The appearance of receptor binding activity and an immunological analysis of the receptor using Triton solubilized membrane proteins show little receptor present in luteal...

journal_title：Biochemical and biophysical research communications

authors： Hansbury MJ,McIlroy PJ,Goldenthal MJ

更新日期：1990-09-14 00:00:00

abstract：:Dexamethasone (DEX), a potent glucocorticoid, increased the expression of T-cell death associated gene 8 (TDAG8), a proton-sensing G protein-coupled receptor, which is associated with the enhancement of acidic pH-induced cAMP accumulation, in peritoneal macrophages. We explored the role of increased TDAG8 expression i...

journal_title：Biochemical and biophysical research communications

authors： He XD,Tobo M,Mogi C,Nakakura T,Komachi M,Murata N,Takano M,Tomura H,Sato K,Okajima F

更新日期：2011-12-02 00:00:00

abstract：:Ascorbate and several phenolic compounds readily oxidise in cell culture media to generate hydrogen peroxide. However, addition of α-ketoglutarate, which is known to be released by several cell types, decreased the levels of H(2)O(2), and the α-ketoglutarate was depleted and converted to succinate. These observations ...

journal_title：Biochemical and biophysical research communications

authors： Long LH,Halliwell B

更新日期：2011-03-04 00:00:00

abstract：:Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is a new promising target for prevention and treatment of cardiac hypertrophy and heart failure. There are three δ isoforms of CaMKII in the heart and previous studies focused primarily on δB and δC types. Here we report the δA isoform of CaMKII is also critically...

journal_title：Biochemical and biophysical research communications

authors： Li C,Cai X,Sun H,Bai T,Zheng X,Zhou XW,Chen X,Gill DL,Li J,Tang XD

更新日期：2011-05-27 00:00:00

abstract：:Alpha 1-acid glycoprotein (AGP) complementary DNA clone has been isolated from an acute phase rabbit liver library. Complete and full-length nucleotide sequence of this cDNA has been determined. The cDNA contains 35 nucleotides 5' untranslated region followed by 606 nucleotides of coding region and a 112 nucleotides 3...

journal_title：Biochemical and biophysical research communications

authors： Ray BK,Ray A

更新日期：1991-07-31 00:00:00

abstract：:MicroRNAs (miRNAs) that negatively regulate gene expression have emerged as novel therapeutic tools for cancer treatment. In this study, we investigated the potential role of Liver receptor homolog-1 (LRH-1), a novel oncogene, in non-small-cell lung cancer (NSCLC), and examined the regulation of LRH-1 by miRNAs. We fo...

journal_title：Biochemical and biophysical research communications

authors： Jiang W,Tian Y,Jiang S,Liu S,Zhao X,Tian D

更新日期：2016-05-13 00:00:00

abstract：:Internal backbone dynamic motions are essential for different protein functions and occur on a wide range of time scales, from femtoseconds to seconds. Molecular dynamic (MD) simulations and nuclear magnetic resonance (NMR) spin relaxation measurements are valuable tools to gain access to fast (nanosecond) internal mo...

journal_title：Biochemical and biophysical research communications

authors： Liu Q,Shi C,Yu L,Zhang L,Xiong Y,Tian C

更新日期：2015-02-13 00:00:00

abstract：:The main protein of enriched and purified amyloid from Octodon degus pancreatic islets was identified as insulin. The material was reduced and alkylated and the A- and the B-chain were separated by reversed phase chromatography and subjected to Edman degradation and amino acid analysis. It was shown that the A-chain c...

journal_title：Biochemical and biophysical research communications

authors： Hellman U,Wernstedt C,Westermark P,O'Brien TD,Rathbun WB,Johnson KH

更新日期：1990-06-15 00:00:00

abstract：:Consumption of a single serving of tomatoes by healthy human volunteers was sufficient to alter levels of oxidative DNA base damage in white cell DNA within 24 h. Levels of the mutagenic oxidized purine base 8-hydroxyguanine decreased, especially in those subjects whose initial levels of this base were higher than the...

journal_title：Biochemical and biophysical research communications

authors： Rehman A,Bourne LC,Halliwell B,Rice-Evans CA

更新日期：1999-09-07 00:00:00