Compensation for spectacle lenses involves changes in proteoglycan synthesis in both the sclera and choroid.

abstract：PURPOSE:To assess histopathologic prognostic factors relative to clinical ones in predicting local recurrence and survival after primary conjunctival melanoma (CM). METHODS:85 patients with CM were identified in Finland between 1967 and 2000, and 70 primary tumors were available for histopathologic study. Time to firs...

journal_title：Current eye research

authors： Tuomaala S,Toivonen P,Al-Jamal R,Kivelä T

更新日期：2007-11-01 00:00:00

abstract：PURPOSE:To examine the effects of external modulation of epithelial-mesenchymal interaction on conjunctival epithelial cell differentiation characteristics. METHODS:Keratin K4 and laminin beta2 chain protein localization was examined in an organotypic model which facilitates the comparison of differentiation character...

journal_title：Current eye research

authors： Kurpakus MA,Lin L

更新日期：1999-01-01 00:00:00

abstract：:This study reports on serum interleukin 2-receptor (IL-2R) levels in uveitis patients. IL-2R is the mediator protein of interleukin 2 (IL-2), a mitogenetic cytokine of primarily immune cell interaction. Stimulated T-cells readily express IL-2R on their cell surface and release a soluble form into serum. The measuremen...

journal_title：Current eye research

authors： Arocker-Mettinger E,Asenbauer T,Ulbrich S,Grabner G

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To determine, by a plaque reduction assay, the in vitro efficacy of novel antiviral agents in the treatment of feline herpes virus 1 (FHV-1) keratitis in the domestic cat (Felis felis). MATERIALS AND METHODS:A standard plaque reduction assay was performed using a laboratory strain of FHV-1 and embryo-derived f...

journal_title：Current eye research

authors： Williams DL,Fitzmaurice T,Lay L,Forster K,Hefford J,Budge C,Blackmore K,Robinson JC,Field HF

更新日期：2004-08-01 00:00:00

abstract：:Processing of visual information within the retina depends in large measure upon a complement of chemical neurotransmitters which are released at synaptic contacts between individual neurons. Numerous investigators have participated in the identification of many of these transmitters and their assignment to specific n...

journal_title：Current eye research

authors： Pourcho RG

更新日期：1996-07-01 00:00:00

abstract：:Objectives: To investigate the characteristics of margin reflex distance 1 (MRD1) asymmetry in congenital lower eyelid epiblepharon and its resolution after surgical correction of epiblepharon. Methods: Among patients who underwent lower eyelid epiblepharon surgery from November 2015 to September 2017, patients with a...

journal_title：Current eye research

authors： Yang MK,Kim N,Choung HK,Khwarg SI

更新日期：2020-12-15 00:00:00

abstract：PURPOSE:Deficiency in Cystathionine β-synthase (CBS) leads to an abnormal accumulation of homocysteine and results in classical homocystinuria, a multi-systemic disorder that affects connective tissue, muscles, the central nervous system, and the eyes. However, the genetic players and mechanisms underlying vision alter...

journal_title：Current eye research

authors： Flores-Flores M,Moreno-García L,Castro-Martínez F,Nahmad M

更新日期：2020-09-07 00:00:00

abstract：:Purpose: To evaluate the correlation between pain during cataract surgery and preoperative anxiety.Methods: This prospective observational masked study included 103 eyes of 103 consecutive patients who underwent routine clear corneal incision phacoemulsification surgery at the Department of Ophthalmology, Rambam Healt...

journal_title：Current eye research

authors： Socea SD,Abualhasan H,Magen O,Zayit-Soudry S,Blumenthal EZ,Duvdevan N,Mimouni M

更新日期：2020-04-01 00:00:00

abstract：:The effects of light damage were studied in four inbred strains of albino rats, Fischer (F344), Lewis (L), Wistar (W), and Buffalo (BUF). Thirty-five-day-old rats (3 from each strain) were kept in cyclic light for two weeks, after which they were exposed to constant fluorescent light (180-190 foot-candles, 490-580 nm)...

journal_title：Current eye research

authors： Borges JM,Edward DP,Tso MO

更新日期：1990-08-01 00:00:00

abstract：PURPOSE:Folic acid (FA) is an essential nutrient for normal embryonic development. FA deficiency (FAD) in maternal diet increases the risk of several defects among the progeny, especially, neural tube defects. The eye begins its development from the neural tube; however, the relationship between FAD and ocular developm...

journal_title：Current eye research

authors： Sijilmassi O,López-Alonso JM,Del Río Sevilla A,Murillo González J,Barrio Asensio MDC

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:In the limbo-corneal epithelium the stem and early precursor epithelial cell pool is confined to the limbal rim. Among the features associated with this spatial segregation is the general paucity of connexin43 (Cx43) within the limbal basal cell population and its complete absence in resident stem cells. The li...

journal_title：Current eye research

authors： Wolosin JM,Schütte M,Zieske JD,Budak MT

更新日期：2002-06-01 00:00:00

abstract：:Trabecular meshwork cells from an inbred strain of mice (A/J) were established in tissue culture. Within 1 hour of enucleation, tissue containing the cornea and the chamber angle was excised and placed in tissue culture. Two to five days later, three cell types grew from the explants. Two of these cell types, corneal ...

journal_title：Current eye research

authors： Begley CG,Yue BY,Hendricks RL

更新日期：1991-11-01 00:00:00

abstract：PURPOSE:To investigate orbital biomechanical properties in patients with thyroid orbitopathy and in age- and gender-matched healthy subjects using the Corvis-ST (CST, Oculus Wetzlar, Germany). METHODS:The CST allows a non-contact tonometry with an ultra-high-speed Scheimpflug device to record the deformation of the co...

journal_title：Current eye research

authors： Leszczynska A,Moehler K,Spoerl E,Ramm L,Herber R,Pillunat LE,Terai N

更新日期：2018-03-01 00:00:00

abstract：:The ocular penetration pathways of three alpha 2-adrenergic agents (p-aminoclonidine, AGN 190342, and clonidine) were investigated in rabbits both in vitro and in vivo. The corneal permeabilities of the compounds correlated positively with their octanol/water distribution coefficients. The ocular drug absorption via c...

journal_title：Current eye research

authors： Chien DS,Homsy JJ,Gluchowski C,Tang-Liu DD

更新日期：1990-11-01 00:00:00

abstract：:Rainbow trout (Oncorhynchus mykiss) were used to model the solar radiation-induced cataract that occurs in hatchery-reared lake trout (Salvelinus namaycush). Rainbow trout eyes were exposed to wideband predominantly UVB radiant energy from a filtered 1000W xenon source. Lenticular damage was assessed and classified an...

journal_title：Current eye research

authors： Cullen AP,Monteith-McMaster CA

更新日期：1993-02-01 00:00:00

abstract：:Change of urate and ascorbate levels in retinae of rat left eyes after ophthalmic artery and optic nerve ligation was studied by reversed-phase high-performance liquid chromatography with electrochemical detection. The right eyes were used for sham operation. We found that uric acid levels in the retinae of the left e...

journal_title：Current eye research

authors： Iriyama K,Yoshiura M,Iwamoto T,Kamada Y,Nozawa H,Mizuno A,Matsuzaki H

更新日期：1986-07-01 00:00:00

abstract：PURPOSE:Previous studies showed that lutein and zeaxanthin, the major human retinal carotenoids, are concentrated in the macula. In this study, the carotenoids in human macular and peripheral retina and the retinal pigment epithelium (RPE) were analyzed. They were also determined in the rod outer segments (ROS) before ...

journal_title：Current eye research

authors： Sommerburg OG,Siems WG,Hurst JS,Lewis JW,Kliger DS,van Kuijk FJ

更新日期：1999-12-01 00:00:00

abstract：:Recent reports from this laboratory indicate that dopamine (DA2) agonists can lower intraocular pressure (IOP) in rabbits, monkeys and rats. This communication suggests that the cat nictitating membrane (CNM) preparation is a useful model for localizing the site(s) and mechanism(s) of action of dopamine (DA2) agonists...

journal_title：Current eye research

authors： Potter DE,Burke JA

更新日期：1984-11-01 00:00:00

abstract：PURPOSE:To evaluate macular ganglion cell complex (GCC) thickness and peripapillary retinal nerve fiber layer (RNFL) thickness in patients treated with SSRIs. METHODS:The present study included 62 eyes of 31 patients who were using SSRIs and 60 eyes of 30 healthy, age- and gender-matched control subjects. All patients...

journal_title：Current eye research

authors： Guclu H,Gorgulu Y,Gurlu VP,Kose Cinar R,Ozal SA,Çaliyurt O

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:Transplantation of in vitro cultured limbal epithelial stem cells (LESCs) is a treatment widely used for LESC deficiency. However, the number of limbal tissue donors is limited, and protocols for LESC cultivation often include compounds and/or feeder layers that can induce side effects and/or increase the cost ...

journal_title：Current eye research

authors： López-Paniagua M,Nieto-Miguel T,de la Mata A,Galindo S,Herreras JM,Corrales RM,Calonge M

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:Human beta-defensins 1 and 2 (hBD-1, -2) are antimicrobial peptides found in several epithelia including corneal epithelium. Breach of the epithelium leaves the cornea vulnerable to infection so we sought to determine if there is an increase in defensin expression after injury. METHODS:The epithelium from huma...

journal_title：Current eye research

authors： McDermott AM,Redfern RL,Zhang B

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:Dry eye is a common condition known to have many systemic co-morbidities. We aim to report the frequency of depression and anxiety suspects in eye clinic patients and explore the association between dry eye signs and symptoms with depression and anxiety. MATERIALS AND METHODS:Adult outpatients were recruited f...

journal_title：Current eye research

authors： Liyue H,Chiang PP,Sung SC,Tong L

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:Several procedures in cataract surgery carry the risk of high temperature increases in the capsular bag. The present study was undertaken to determine the shrinkage temperature of the human lens capsule and to investigate the effect of temperature on the mechanical behavior of the lens capsule. METHOD:Thermal-...

journal_title：Current eye research

authors： Krag S,Danielsen CC,Andreassen TT

更新日期：1998-05-01 00:00:00

abstract：PURPOSE:Retinal ischemia and neovascularization (NV) are important components of many retinal disorders. To facilitate further investigation of retinal ischemia and neovascularization, we sought to develop a reproducible in vivo experimental model of venous occlusion by photodynamic thrombosis in rats. METHODS:After a...

journal_title：Current eye research

authors： Saito Y,Park L,Skolik SA,Alfaro DV,Chaudhry NA,Barnstable CJ,Liggett PE

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:To explore the in vitro proliferative potential of human limbal epithelial cells after 31 degrees C organ-culture storage and to investigate putative factors influencing it. METHODS:185 cultures of limbal explants were carried-out either from full-thickness explants (n = 102) or from enzymatically dissociated ...

journal_title：Current eye research

authors： Zito-Abbad E,Borderie VM,Baudrimont M,Bourcier T,Laroche L,Chapel C,Uzel JL

更新日期：2006-05-01 00:00:00

abstract：:The mechanism of oxidative damage to the lens through intraocular photochemical generation of superoxide and its derivatization to other oxidants such as singlet oxygen, hydroxyl radical and hydrogen peroxide has been studied. Rat lenses when organ cultured aerobically in TC 199 containing additional amounts of ribofl...

journal_title：Current eye research

authors： Varma SD,Chand D,Sharma YR,Kuck JF Jr,Richards RD

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:The high prevalence of positive family history of keratoconus (KC) in KC patients is well-known. However, the results regarding the association between family history of KC and disease severity are controversial. The aim of this study was to evaluate the possible association between family history and severity ...

journal_title：Current eye research

authors： Naderan M,Rajabi MT,Zarrinbakhsh P,Naderan M,Bakhshi A

更新日期：2016-11-01 00:00:00

abstract：:Phosphatidic acid (PA) is an obligate intermediate in the phosphatidylinositol (PI) cycle and may serve as a sensitive marker for this pathway of reactions. Previously, we have shown that acetylcholine (ACh) stimulates formation of labeled PA in whole rat corneas whose phospholipids were prelabeled with [14C]arachidon...

journal_title：Current eye research

authors： Baratz KH,Proia AD,Klintworth GK,Lapetina EG

更新日期：1987-05-01 00:00:00

abstract：:We examined jun-B gene expression in the rat retina after a focal retinal injury by in situ hybridization. 30 min after producing a penetrating retinal wound, the retina showed the expression of jun-B mRNA intensively in the inner nuclear layer (INL) and relatively sparsely in the ganglion cell layer. The double-label...

journal_title：Current eye research

authors： Ohki K,Yoshida K,Yamakawa A,Harada T,Matsuda H,Imaki J

更新日期：1995-11-01 00:00:00

abstract：:The effect of cyclosporine (CsA) treatment in both primary and secondary Chlamydia trachomatis ocular infection in cynomolgus monkeys was studied. Following primary infection, CsA-treated animals developed severe clinical symptoms which persisted for up to 12 weeks compared to control animals which developed less seve...

journal_title：Current eye research

authors： Young E,Schachter J,Prendergast RA,Taylor HR

更新日期：1987-05-01 00:00:00