Abstract：
PURPOSE AND METHODS:To describe the clinical and histopathologic features of a patient with viral retinitis secondary to subacute sclerosing panencephalitis. RESULTS:The patient was a human immunodeficiency virus-negative intravenous drug abuser with an acute retinitis that later progressed to encephalitis despite aggressive treatment for possible viral, protozoal, bacterial, and rickettsial infections. The patient had many of the characteristic findings of subacute sclerosing panencephalitis, including a history of measles in early childhood, myoclonus, periodic complexes on electroencephalographic testing, persistently elevated serum and cerebrospinal fluid antimeasles immunoglobulin G (IgG) titers, and a cerebrospinal fluid oligoclonal IgG gammopathy. Ultrastructural examination demonstrated numerous filamentous microtubular intranuclear viral inclusions in the nuclear layers of the retina consistent with the measles virus. This case is unusual in that our patient developed subacute sclerosing panencephalitis later in life and because there was an 8-year period between presumed viral infections in the two eyes. CONCLUSIONS:An acute retinitis in an intravenous drug abuser is not always caused by human immunodeficiency virus-related infections; not all viral retinitis responds to therapy; and mortality as well as the usual morbidity may be associated with viral retinitis. One might consider the diagnosis of subacute sclerosing panencephalitis in a young person with an acute retinitis with little or no vitreal inflammation and lack of response to anticytomegalovirus and antitoxoplasmosis therapy.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Park DW,Boldt HC,Massicotte SJ,Akang EE,Roos KL,Bodnar A,Pless J,Ghetti B,Pascuzzi RMdoi
10.1016/s0002-9394(14)70179-5subject
Has Abstractpub_date
1997-04-01 00:00:00pages
533-42issue
4eissn
0002-9394issn
1879-1891pii
S0002-9394(14)70179-5journal_volume
123pub_type
杂志文章abstract：PURPOSE:To determine the repeatability of automated retinal and choroidal thickness measurements with swept-source optical coherence tomography (SS OCT) and the frequency and type of scan artifacts. DESIGN:Prospective evaluation of new diagnostic technology. METHODS:Thirty healthy subjects were recruited prospectivel...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2014-05-01 00:00:00
abstract：PURPOSE:To determine with electronic monitoring an objective measurement of adherence in two populations of subjects: those using once-daily prostaglandin analogs as sole ocular hypotensive therapy (one-drug group) and those requiring an adjunctive medicine to the prostaglandin analog (two-drug group). DESIGN:Single-s...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2007-10-01 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：2013-12-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.05.035
更新日期：2010-11-01 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：2018-10-01 00:00:00
abstract：:Eight patients with manifest latent nystagmus, as noted by ocular movement recordings, were examined for nystagmus reduction after surgical or optical treatment. Seven of the patients had strabismus. Five patients underwent strabismus surgery, had no tropia postoperatively, and the manifest latent nystagmus converted ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76985-5
更新日期：1990-08-15 00:00:00
abstract：:We analyzed 34 sets of optic disk photographs from 19 patients with glaucoma who had been followed up for ten years to evaluate changes in the position of the vasculature of the optic disks over time. Each photograph was analyzed by an image analyzer's edge-defining program for optic disk analysis and by three experie...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1987-11-15 00:00:00
abstract：PURPOSE:To clarify the clinical characteristics of reticular pseudodrusen in Korean patients. DESIGN:Retrospective, observational, consecutive case series. METHODS:A total of 255 eyes of 130 patients diagnosed with reticular pseudodrusen were evaluated. Reticular pseudodrusen were diagnosed by characteristic fundus f...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.08.012
更新日期：2012-03-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1986-12-15 00:00:00
abstract：:Dipivefrin, an epinephrine prodromal drug, was used in conjunction with timolol maleate to evaluate the safety and effectiveness of combined therapy. Seventeen patients who had used timolol maleate for at least six months added dipivefrin (Group 1) and seven patients who had used dipivefrin for at least six months add...
journal_title：American journal of ophthalmology
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更新日期：1981-02-01 00:00:00
abstract：:We evaluated the effect of a collagen shield on epithelial healing in keratectomy wounds in rabbit eyes. Superficial keratectomies 6 mm in diameter were created in 12 eyes of six rabbits. Six eyes received collagen shields every eight hours; six eyes received no treatment (control group). Epithelial healing was signif...
journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2014-02-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2005-01-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2012.02.018
更新日期：2012-08-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(85)90514-8
更新日期：1985-09-15 00:00:00
abstract：PURPOSE:To present the first detailed assessment of the clinical features of CL-induced subconjunctival hemorrhage and associated risk factors. DESIGN:Cross-sectional and case-control study of age-matched randomized groups. METHODS:A total of 45 CL wearers with subconjunctival hemorrhage aged 18 to 45 years (CL-Hemor...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.05.028
更新日期：2010-11-01 00:00:00
abstract：:In the elderly patient with a massive vitreous hemorrhage in one eye and senile macular choroidal degenerative changes in the fellow eye, a hemorrhagic disciform detachment causing this massive vitreous hemorrhage must be considered in the differential diagnosis. Ultrasonography selectively combined with radioactive p...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75023-8
更新日期：1980-10-01 00:00:00
abstract：:The pathogenesis of reversible cupping of the optic disk in congenital glaucoma was examined by two approaches. Human fetal, neonatal, and adult eyes were examined by histochemistry and electron microscopy to delineate the embryologic development of the optic nerve head. While the neural, glial, and vascular elements ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(77)90680-8
更新日期：1977-09-01 00:00:00
abstract：PURPOSE:To describe a modified technique of haptic externalization during repositioning of dislocated posterior chamber lens implants, which facilitates placement of scleral fixation sutures around the haptic for implant stabilization. METHODS:We describe a technique of repositioning a dislocated posterior chamber imp...
journal_title：American journal of ophthalmology
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更新日期：2001-01-01 00:00:00
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更新日期：1986-11-15 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2020-06-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2018-05-01 00:00:00
abstract：:The noninvasive laser Doppler technique was used to study retinal circulatory characteristics in five patients who underwent uncomplicated scleral buckling procedures. In each patient, the systolic/diastolic variation of the red blood cell speed in the retinal arteries (flow pulsatility ratio) was lower in the eye tha...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1983-02-01 00:00:00
abstract：:Visual field loss secondary to optic disk drusen became evident before the development of angioid streaks in a patient with pseudoxanthoma elasticum. The incidence of optic disk drusen in cases of pseudoxanthoma elasticum is 20 to 50 times greater than that in the healthy population. We postulate that the abnormal agg...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76696-6
更新日期：1991-08-15 00:00:00
abstract：:Total outflow facility was determined in cynomolgus monkeys by two-level constant pressure perfusion. Topical epinephrine increased facility by 30% to 35% three to four hours after dosing, whether given as a single 600-micrograms dose or as twice daily 600-micrograms doses for three days. A single 5.5-micrograms intra...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75985-9
更新日期：1990-02-15 00:00:00
abstract：PURPOSE:To assess the role of muscular degeneration, we evaluated the correlation between ptosis severity and levator muscle function. DESIGN:Retrospective cohort study. METHODS:The medical records of 136 patients (53 men and 83 women; mean age, 67 years) with acquired blepharoptosis were reviewed for levator functio...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.02.002
更新日期：2008-06-01 00:00:00
abstract：PURPOSE:To measure accurately the amount of cyclotorsion. METHODS:A horizontal light beam of the slit lamp is projected on the retina, crossing the fovea. The slit light will normally cross between the middle and lower thirds of the disk. Cyclotorsion of the eye will cause the horizontal slit-light beam to be projecte...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70402-7
更新日期：1996-12-01 00:00:00
abstract：PURPOSE:To determine the effects of a second fluocinolone implant inserted in eyes with uveitis in which recurrent inflammation developed after the original implant was placed. DESIGN:Prospective, interventional trial. METHODS:Study subjects comprised all consecutive patients with noninfectious posterior uveitis who ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.11.008
更新日期：2008-04-01 00:00:00
abstract：PURPOSE:To report a transient cataract after bleb needling and subconjunctival injection of 5-fluorouracil. DESIGN:Observational case report. METHODS:A 51-year-old man had an encapsulated bleb after filtering surgery. The bleb was needled, and 5 mg of 5-fluorouracil was injected adjacent to the bleb. RESULTS:Within ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01828-7
更新日期：2003-01-01 00:00:00
