In vitro reconstitution of a functional duck hepatitis B virus reverse transcriptase: posttranslational activation by Hsp90.

abstract：:Primary human embryonic kidney (HEK) cells were transformed by a focus assay with BK virus (BKV) DNA molecularly cloned at its unique EcoRI site. Both viral DNA sequences and viral tumor antigens were present and expressed in all the foci that we examined. However, cells isolated from foci were incapable of growth in ...

journal_title：Journal of virology

authors： Pater A,Pater MM

更新日期：1986-05-01 00:00:00

abstract：:Nipah virus (NiV) and Hendra virus (HeV) are emerging zoonotic viruses and the causative agents of severe respiratory disease and encephalitis in humans. Little is known about the mechanisms that govern the development of respiratory and neurological disease. Using a hamster model of lethal NiV and HeV infection, we d...

journal_title：Journal of virology

authors： Rockx B,Brining D,Kramer J,Callison J,Ebihara H,Mansfield K,Feldmann H

更新日期：2011-08-01 00:00:00

abstract：:The ability of human immunodeficiency virus type 1 (HIV-1) to transduce nondividing cells is key to infecting terminally differentiated macrophages, which can serve as a long-term reservoir of HIV-1 infection. The mutation N57A in the viral CA protein renders HIV-1 cell cycle dependent, allowing examination of HIV-1 i...

journal_title：Journal of virology

authors： Fischer DK,Saito A,Kline C,Cohen R,Watkins SC,Yamashita M,Ambrose Z

更新日期：2019-04-17 00:00:00

abstract：:A widespread porcine epidemic diarrhea virus (PEDV) occurred in southern China during 2010 to 2012. A virulent field PEDV strain, GD-B, was isolated from a sucking piglet suffering from severe diarrhea in Guangdong, China. We sequenced and analyzed the complete genome of strain GD-B, which will promote a better unders...

journal_title：Journal of virology

authors： Luo Y,Zhang J,Deng X,Ye Y,Liao M,Fan H

更新日期：2012-09-01 00:00:00

abstract：:Forty isolates of herpes simplex virus were compared by means of cross-neutralization curves. The 11 oral isolates were serotype 1, and all 29 genital/anal isolates were serotype 2. The cytopathic effects of the two serotypes were consistently different. Passage of strains of type 1 and type 2 in mice and in rabbits y...

journal_title：Journal of virology

authors： Plummer G,Waner JL,Phuangsab A,Goodheart CR

更新日期：1970-01-01 00:00:00

abstract：:Vaccinia extracellular enveloped virus (EEV) is critical for cell-to-cell and long-range virus spread both in vitro and in vivo. The B5R gene encodes an EEV-specific type I membrane protein that is essential for efficient EEV formation. The majority of the B5R ectodomain consists of four domains with homology to short...

journal_title：Journal of virology

authors： Aldaz-Carroll L,Whitbeck JC,Ponce de Leon M,Lou H,Hirao L,Isaacs SN,Moss B,Eisenberg RJ,Cohen GH

更新日期：2005-05-01 00:00:00

abstract：UNLABELLED:JC polyomavirus (JCPyV) infection of immunocompromised individuals results in the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML). The viral capsid of JCPyV is composed primarily of the major capsid protein virus protein 1 (VP1), and pentameric arrangement of VP1 monomers results...

journal_title：Journal of virology

authors： Nelson CD,Ströh LJ,Gee GV,O'Hara BA,Stehle T,Atwood WJ

更新日期：2015-04-01 00:00:00

abstract：:The tax gene of the human T-cell leukemia virus types I and II (HTLV-I and HTLV-II) is essential for viral replication and acts by increasing the level of RNA transcription. The tax genes of HTLV-I and HTLV-II encode proteins of 40 and 37 kilodaltons, respectively. By in vitro mutagenesis of the tax gene, we have inve...

journal_title：Journal of virology

authors： Cann AJ,Rosenblatt JD,Wachsman W,Chen IS

更新日期：1989-03-01 00:00:00

abstract：:Nine virulent bacteriophages of the anaerobe Corynebacterium (Propionibacterium) acnes, the P-a series, are DNA phages, with long, curved nonretractile tails (130 nm) without tail plates or fibers. They have isometric heads (420 by 460 nm), and are placed in Bradley's group B-1. There is permanent plaque suppression a...

journal_title：Journal of virology

authors： Zierdt CH

更新日期：1974-11-01 00:00:00

abstract：:Actively replicating endogenous retroviruses entered the human genome millions of years ago and became a stable part of the inherited genetic material. They subsequently acquired multiple mutations, leading to the assumption that these viruses no longer replicate. However, certain human tumor cell lines have been show...

journal_title：Journal of virology

authors： Contreras-Galindo R,Kaplan MH,Leissner P,Verjat T,Ferlenghi I,Bagnoli F,Giusti F,Dosik MH,Hayes DF,Gitlin SD,Markovitz DM

更新日期：2008-10-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) B capsids are composed of seven proteins, designated VP5, VP19C, 21, 22a, VP23, VP24, and VP26 in order of decreasing molecular weight. Three proteins (21, 22a, and VP24) are encoded by a single open reading frame (ORF), UL26, and include a protease whose structure and function have...

journal_title：Journal of virology

authors： Desai P,Watkins SC,Person S

更新日期：1994-09-01 00:00:00

abstract：:trans activation of the human immunodeficiency virus type 1 long terminal repeat requires that the viral trans activator Tat interact with the trans-acting responsive region (TAR) RNA. Although the N-terminal 47 amino acids represent an independent activation domain that functions via heterologous nucleic acid-binding...

journal_title：Journal of virology

authors： Luo Y,Peterlin BM

更新日期：1993-06-01 00:00:00

abstract：UNLABELLED:In vitro, infection of polarized human intestinal epithelial cells by coxsackievirus B3 (CVB3) depends on virus interaction with decay-accelerating factor (DAF), a receptor expressed on the apical cell surface. Although mice are highly susceptible to CVB3 infection when virus is delivered by intraperitoneal ...

journal_title：Journal of virology

authors： Pan J,Zhang L,Odenwald MA,Shen L,Turner JR,Bergelson JM

更新日期：2015-04-01 00:00:00

abstract：:The RNA genomes from the cardioviruses, hepatoviruses, and aphthoviruses encode two to five tandem pseudoknots within their 5' untranslated regions. These pseudoknots lie adjacent to a pyrimidine-rich sequence, which in cardio- and aphthoviruses takes the form of a homopolymeric poly(C) tract. Seven deletion mutations...

journal_title：Journal of virology

authors： Martin LR,Palmenberg AC

更新日期：1996-11-01 00:00:00

abstract：:Cytotoxic T lymphocytes (CTLs) are important for the control of virus replication during respiratory infections. For human metapneumovirus (hMPV), an H-2(d)-restricted CTL epitope in the M2-2 protein has been described. In this study, we screened the hMPV F, G, N, M, M2-1, and M2-2 proteins using three independent alg...

journal_title：Journal of virology

authors： Melendi GA,Zavala F,Buchholz UJ,Boivin G,Collins PL,Kleeberger SR,Polack FP

更新日期：2007-10-01 00:00:00

abstract：:The presence or absence of the receptor CD4 and the coreceptors CCR5 and CXCR4 restrict the cell tropism of human immunodeficiency virus type 1 (HIV-1). Despite the importance of thymic infection by HIV-1, conflicting reports regarding the expression of HIV-1 coreceptors on human thymocytes have not been resolved. We ...

journal_title：Journal of virology

authors： Taylor JR Jr,Kimbrell KC,Scoggins R,Delaney M,Wu L,Camerini D

更新日期：2001-09-01 00:00:00

abstract：:Influenza A H9N2 viruses are common poultry pathogens that occasionally infect swine and humans. It has been shown previously with H9N2 viruses that reassortment can generate novel viruses with increased transmissibility. Here, we demonstrate the modeling power of a novel transfection-based inoculation system to selec...

journal_title：Journal of virology

authors： Kimble JB,Angel M,Wan H,Sutton TC,Finch C,Perez DR

更新日期：2014-01-01 00:00:00

abstract：:Adenovirus types 5 and 3 (Ad5 and Ad3), two human adenovirus serotypes of evolutionarily divergent subgroups, show very different levels of E1A gene expression early after infection of permissive cells. Since adenovirus E1A gene expression is known to be transcriptionally autoregulated, we have investigated the differ...

journal_title：Journal of virology

authors： Jones SN,Tibbetts C

更新日期：1989-04-01 00:00:00

abstract：:Canine distemper virus attachment (hemagglutinin [H] equivalent) and fusion (F) antigens were purified by affinity chromatography with monoclonal antibodies. The purified antigens were used to immunize groups of three dogs. Radioimmune precipitation assays with sera from these animals showed that the F antigen prepara...

journal_title：Journal of virology

authors： Norrby E,Utter G,Orvell C,Appel MJ

更新日期：1986-05-01 00:00:00

abstract：:Immunogenic regions of the gp41 transmembrane protein of human immunodeficiency virus type 1 (HIV-1) were previously mapped by examining polyclonal sera from HIV-infected patients and rodent polyclonal and monoclonal antibodies (MAbs) to peptides of gp41. To define the epitopes within these regions to which infected h...

journal_title：Journal of virology

authors： Xu JY,Gorny MK,Palker T,Karwowska S,Zolla-Pazner S

更新日期：1991-09-01 00:00:00

abstract：:Specific cleavage of BK virus (MM) DNA with restriction endonuclease MboI gives rise to 10 fragments. Two techniques were used to determine the location of these fragments on the viral genome with respect to the three known sites for HindIII cleavage. In the first method, reciprocal digestion, individual MboI fragment...

journal_title：Journal of virology

authors： Yang RC,Wu R

更新日期：1978-09-01 00:00:00

abstract：:Zyxin, a focal adhesion molecule, interacts specifically with the E6 protein from human papillomavirus (HPV) type 6 in a yeast two-hybrid screen of a cDNA library prepared from human keratinocytes. Zyxin does not interact significantly with E6 proteins from HPV types 11, 16, or 18. The interaction was confirmed by in ...

journal_title：Journal of virology

authors： Degenhardt YY,Silverstein S

更新日期：2001-12-01 00:00:00

abstract：:As part of the continuing effort to develop an effective HIV vaccine, we generated a poxviral vaccine vector (previously described) designed to improve on the results of the RV144 phase III clinical trial. The construct, NYVAC-KC, is a replication-competent, attenuated recombinant of the vaccinia virus strain NYVAC. N...

journal_title：Journal of virology

authors： Kibler KV,Asbach B,Perdiguero B,García-Arriaza J,Yates NL,Parks R,Stanfield-Oakley S,Ferrari G,Montefiori DC,Tomaras GD,Roederer M,Foulds KE,Forthal DN,Seaman MS,Self S,Gottardo R,Phogat S,Tartaglia J,Barnett S,Cris

更新日期：2019-01-17 00:00:00

abstract：:The inactivation of type C retroviruses by human serum may be a considerable impediment to the use of retroviral vectors in vivo for gene therapy. Here we show that virus inactivation is dependent both on the virus and on the cell line used to produce the virus. All viruses produced from murine NIH 3T3 or dog Cf2ThS+L...

journal_title：Journal of virology

authors： Takeuchi Y,Cosset FL,Lachmann PJ,Okada H,Weiss RA,Collins MK

更新日期：1994-12-01 00:00:00

abstract：:Dendritic cells are central to the early events of human immunodeficiency virus type 1 (HIV-1) transmission, but HIV-1 infects dendritic cells inefficiently in vitro compared to activated CD4(+) T cells. There is a strong postentry restriction of HIV-1 infection in dendritic cells, partly mediated by the cellular rest...

journal_title：Journal of virology

authors： Pion M,Stalder R,Correa R,Mangeat B,Towers GJ,Piguet V

更新日期：2007-11-01 00:00:00

abstract：:The fundamental question of whether a primed immune system is capable of preventing latent gammaherpesvirus infection remains unanswered. Recent studies showing that vaccination can reduce acute replication and short-term latency but cannot alter long-term latency further call into question the possibility of achievin...

journal_title：Journal of virology

authors： Tibbetts SA,McClellan JS,Gangappa S,Speck SH,Virgin HW 4th

更新日期：2003-02-01 00:00:00

abstract：:The herpes simplex virus genome consists of two components, L and S, that invert relative to each other to yield four isomeric arrangements, prototype (P), inversion of the S component (Is), inversion of the L component (Il), and inversion of both components (Isl). Previous studies have shown that the 500-base-pair a ...

journal_title：Journal of virology

authors： Longnecker R,Roizman B

更新日期：1986-05-01 00:00:00

abstract：:Herpes simplex virus (HSV) codes for several envelope glycoproteins, including glycoprotein G-2 (gG-2) of HSV type 2 (HSV-2), which are dispensable for replication in cell culture. However, clinical isolates which are deficient in such proteins occur rarely. We describe here five clinical HSV-2 isolates which were fou...

journal_title：Journal of virology

authors： Liljeqvist JA,Svennerholm B,Bergström T

更新日期：1999-12-01 00:00:00

abstract：:Translation of picornavirus RNAs is mediated by internal ribosomal entry site (IRES) elements and requires both standard eukaryotic translation initiation factors (eIFs) and IRES-specific cellular trans-acting factors (ITAFs). Unr, a cytoplasmic RNA-binding protein that contains five cold-shock domains and is encoded ...

journal_title：Journal of virology

authors： Boussadia O,Niepmann M,Créancier L,Prats AC,Dautry F,Jacquemin-Sablon H

更新日期：2003-03-01 00:00:00

abstract：:Hypoxia-inducible factor 1 (HIF-1) is a ubiquitously expressed transcriptional regulator involved in induction of numerous genes associated with angiogenesis and tumor growth. Kaposi's sarcoma, associated with increased angiogenesis, is a highly vascularized, endothelial cell-derived tumor. Previously, we have shown t...

journal_title：Journal of virology

authors： Cai Q,Murakami M,Si H,Robertson ES

更新日期：2007-10-01 00:00:00