Abstract：
:Electron microbeam experiments are planned or under way to explore in part the question regarding whether the bystander effect is a general phenomenon or is restricted to high-LET radiation. Since low-LET radiations scatter more readily compared to high-LET radiations, identifying bystander cells and assessing the potential dose that they may receive will be crucial to the interpretation of radiobiological results. This paper reports on initial calculations of the basic information needed for a stochastic model of the penetration of energetic electrons in tissue-like matter; the model will be used to predict doses delivered to adjacent regions in which bystander cells may reside. Results are presented of calculations of the stochastics of energy deposition by 25 keV electrons slowing down in a homogeneous water medium. Energy deposition distributions were scored for 1-micrometer spheres located at various penetration and radial distances up to 10 micrometer from the point of origin. The energy of 25 keV was selected because experiments are planned for that energy. At 25 keV there is a high probability that the entire electron track will be contained within a typical mammalian cell. Individual tracks are scored because of their primacy; data for higher doses can be obtained by convoluting single-track distributions. The event frequency decreases approximately exponentially after the first micrometer to 1% at about 8 micrometer of penetration. Radially, the 1% contour extends to 3.5 micrometer at a penetration of 5.5 micrometer. The frequency-mean energy deposited decreases from 1.5 to 1 keV/micrometer at a penetration of 3.5 micrometer, then increases back to about 1.5 at a penetration of 6.5 micrometer. The mean energy increases to about 3 keV/micrometer at a radial distance of 8.5 micrometer.
journal_name
Radiat Resjournal_title
Radiation researchauthors
Wilson WE,Lynch DJ,Wei K,Braby LAdoi
10.1667/0033-7587(2001)155[0089:moakem]2.0.co;2subject
Has Abstractpub_date
2001-01-01 00:00:00pages
89-94issue
1 Pt 1eissn
0033-7587issn
1938-5404journal_volume
155pub_type
杂志文章abstract：:The purpose of this paper is to validate a metabolic model describing the kinetics of tritium in man. The validation is based on measurements of background levels of loose and bound tritium in Italian subjects and their diets. Model predictions are compared with empirical measurements of tritium in human urine and tis...
journal_title：Radiation research
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更新日期：1984-12-01 00:00:00
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更新日期：1984-02-01 00:00:00
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pub_type： 杂志文章,评审
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journal_title：Radiation research
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doi：
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journal_title：Radiation research
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
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pub_type： 杂志文章
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doi：
更新日期：1997-02-01 00:00:00
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doi：
更新日期：1999-03-01 00:00:00
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pub_type： 杂志文章
doi：
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doi：
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doi：
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doi：
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pub_type： 杂志文章
doi：
更新日期：1968-11-01 00:00:00
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journal_title：Radiation research
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
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journal_title：Radiation research
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
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更新日期：2002-07-01 00:00:00
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journal_title：Radiation research
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更新日期：1997-04-01 00:00:00
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