Non-adrenergic, non-cholinergic influences on parotid acinar degranulation in response to stimulation of the parasympathetic innervation in the anaesthetized rat.

abstract：:The renin-angiotensin system is activated in the early phase of two-kidney, one-clip (2K-1C) hypertension. The paraventricular nucleus (PVN) integrates inputs regulating sympathetic outflow. The PVN receives inputs from plasma angiotensin II via projections from circumventricular organs and from renal afferent nerves ...

journal_title：Experimental physiology

authors： Rossi NF,Maliszewska-Scislo M,Chen H,Black SM,Sharma S,Ravikov R,Augustyniak RA

更新日期：2010-08-01 00:00:00

abstract：:The effects of microinjections of adenosine and an adenosine receptor antagonist into the rostral ventrolateral medulla (RVLM) on the cardiovascular changes associated with the defence reaction were investigated in anaesthetized rats. Responses to electrical and chemical stimulation in RVLM were determined in alpha-ch...

journal_title：Experimental physiology

authors： Thomas T,Spyer KM

更新日期：1996-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Type 2 diabetes is associated with a higher rate of ventricular arrhythmias compared with the non-diabetic population, but the associated myocardial gene expression changes are unknown; furthermore, it is also unknown whether any changes are attributable to chron...

journal_title：Experimental physiology

authors： Ashrafi R,Modi P,Oo AY,Pullan DM,Jian K,Zhang H,Gerges JY,Hart G,Boyett MR,Davis GK,Wilding JPH

更新日期：2017-11-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? Excitation-contraction coupling in fish hearts is maintained over a range of temperatures that would be cardioplegic to most mammals. Here, we review what is known about the fish cardiac ryanodine receptor, and consider how it may be regulated in a different manner from th...

journal_title：Experimental physiology

authors： Shiels HA,Sitsapesan R

更新日期：2015-12-01 00:00:00

abstract：:Chronically hypoxic (CH) and normoxic control rats were used to assess the action of S9581, a water-soluble analogue of almitrine bismesylate. S9581 increased ventilation (Ve) by 34% in control and 20% in CH rats. During acute hypoxia Ve was raised and S9581 caused a further increase of 20% in both groups. Low doses o...

journal_title：Experimental physiology

authors： Bee D,Emery CJ,Howard P

更新日期：1992-11-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Dexmedetomidine has a capacity for sedation, anti-anxiety and analgesia with minimal suppression of respiratory function; what is its role in neuropathic pain and what is the involvement of miRNAs? What is the main finding and its importance? Dexmedetomidine atte...

journal_title：Experimental physiology

authors： Zhang W,Yu T,Cui X,Yu H,Li X

更新日期：2020-09-01 00:00:00

abstract：:We have considered the manner in which data obtained with ion-selective electrodes should be evaluated. The potential difference recorded by such electrodes, with respect to a stable reference, is converted to a concentration by a non-linear transformation--the Nernst or Nikolsky equation. The mean and standard deviat...

journal_title：Experimental physiology

authors： Fry CH,Hall SK,Blatter LA,McGuigan JA

更新日期：1990-03-01 00:00:00

abstract：:Spermine is a low molecular weight polyamine involved in the postnatal maturation of the gut. When it is administered orally to suckling rats, it induces maturation of the intestinal tract (liver, pancreas and small intestine). Here we show that this polyamine is able to induce precocious intestinal and splenic develo...

journal_title：Experimental physiology

authors： Jolois O,Peulen O,Collin S,Simons M,Dandrifosse G,Heinen E

更新日期：2002-01-01 00:00:00

abstract：:A considerable body of evidence indicates that the intracellular chloride concentration ([Cl-]i) is an important regulatory signal in epithelial ion transport. [Cl-]i regulates the open channel probability of sodium and chloride channels, the rate of chloride channel recycling to the apical membrane, cell volume homeo...

journal_title：Experimental physiology

authors： Treharne KJ,Crawford RM,Mehta A

更新日期：2006-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Is lower body negative pressure a useful surrogate to study white blood cell responses to haemorrhage in humans? What is the main finding and its importance? We found that lower body negative pressure appears to be a useful surrogate to study the early white bloo...

journal_title：Experimental physiology

authors： van Helmond N,Johnson BD,Curry TB,Cap AP,Convertino VA,Joyner MJ

更新日期：2016-10-01 00:00:00

abstract：:The present study was designed to analyse the effects of aerobic exercise on the metabolic effects of alloxan. Male Wistar newborn rats (2 days old) received alloxan (200 mg (kg body weight)(-1)) intraperitoneally (A rats). Vehicle-injected rats were used as controls (C rats). At 28 days old, some of the A rats were s...

journal_title：Experimental physiology

authors： de Oliveira CA,Luciano E,de Mello MA

更新日期：2005-01-01 00:00:00

abstract：:The neurohypophysial hormone vasopressin contributes to control of urine output and, while urine flow shows a clear daily rhythm, there has been debate as to whether this is true of neurohypophysial hormones. A study was performed on fifteen adult males, with a mean age of 25 years, over a 24 h period, nine blood samp...

journal_title：Experimental physiology

authors： Forsling ML,Montgomery H,Halpin D,Windle RJ,Treacher DF

更新日期：1998-05-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Does treatment of obstructive sleep apnoea (OSA) with nocturnal oxygen or continuous positive airway pressure (CPAP) improve hypoxic vascular responses, which are reportedly impaired in OSA? What is the main finding and its importance? Cerebrovascular and cardiov...

journal_title：Experimental physiology

authors： Beaudin AE,Hanly PJ,Raneri JK,Sajobi TT,Anderson TJ,Poulin MJ

更新日期：2019-04-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Exercise for type 2 diabetes patients treated with insulin therapy involves the risk of hypoglycaemia. Dipeptidyl peptidase-4 (DPP-4) inhibitors can be effective in combination with exercise because they reduce the incidence of hypoglycaemia. We evaluated the eff...

journal_title：Experimental physiology

authors： Tanimura Y,Aoi W,Mizushima K,Higashimura Y,Naito Y

更新日期：2019-07-01 00:00:00

abstract：:Mechanical properties of the vascular smooth muscle from normal and dystrophin-deficient (mdx) mice were examined. Changes in resting and developed tensions in response to stretch were recorded in isolated portal vein. The vascular segments were elongated in 5 % increments of the 'in situ' length (Lr) up to 1.30Lr. Th...

journal_title：Experimental physiology

authors： Mancinelli R,Tonali P,Romani R,Tringali A,Vargiu R,AZZENA GB

更新日期：1999-09-01 00:00:00

abstract：:Brain blood vessels contain muscarinic receptors that are important for cerebral blood flow (CBF) regulation, but whether a cholinergic receptor mechanism is involved in the exercise-induced increase in cerebral perfusion or affects cerebral metabolism remains unknown. We evaluated CBF and cerebral metabolism (from ar...

journal_title：Experimental physiology

authors： Seifert T,Fisher JP,Young CN,Hartwich D,Ogoh S,Raven PB,Fadel PJ,Secher NH

更新日期：2010-10-01 00:00:00

abstract：:Experiments were performed to investigate, in the normal and acutely inflamed rabbit knee joint, the role of prostaglandins in the regulation of joint blood flow, measured by laser Doppler flowmetry, as well as their modulation of sympathetic vasoconstriction. Close intra-arterial injection of prostaglandin E2 (PGE2) ...

journal_title：Experimental physiology

authors： Najafipour H,Ferrell WR

更新日期：1994-01-01 00:00:00

abstract：:In humans, skeletal muscle blood flow is regulated by an interaction between several locally formed vasodilators, including NO and prostaglandins. In plasma, ATP is a potent vasodilator that stimulates the formation of NO and prostaglandins and, very importantly, can offset local sympathetic vasoconstriction. Adenosin...

journal_title：Experimental physiology

authors： Mortensen SP,Saltin B

更新日期：2014-12-01 00:00:00

abstract：:Increased fetal lung expansion, induced by tracheal obstruction (TO), is a potent stimulus for fetal lung growth, but rapidly reduces surfactant protein (SP) mRNA levels. Our aim was to determine the time course for the re-expression of the surfactant proteins in fetal lung tissue following the release of a TO and to ...

journal_title：Experimental physiology

authors： Lines A,Gillett AM,Phillips ID,Wallace MJ,Hooper SB

更新日期：2001-01-01 00:00:00

abstract：:Early life and preconception environmental stimuli can affect adult health-related phenotypes. Exercise training is an environmental stimulus affecting many systems throughout the body and appears to alter offspring phenotypes. The aim of this study was to examine the influence of parental exercise training, or 'exerc...

journal_title：Experimental physiology

authors： Guth LM,Ludlow AT,Witkowski S,Marshall MR,Lima LC,Venezia AC,Xiao T,Ting Lee ML,Spangenburg EE,Roth SM

更新日期：2013-10-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What are the cellular and molecular determinants of increased risk for cardiovascular disease from prolonged sitting? What is the main finding and its importance? Prolonged sitting, independent of calf raise interruption strategies, decreases microparticle counts...

journal_title：Experimental physiology

authors： Evans WS,Hanson ED,Shill DD,Landers-Ramos RQ,Stoner L,Willey Q,Credeur DP,Prior SJ

更新日期：2020-08-01 00:00:00

abstract：:For synaptic and cellular analyses of the mammalian respiratory network, intracellular recording and good pharmacological access to respiratory neurones is required. Using an existing arterially perfused in situ preparation of neonatal rat, we report on a method allowing stable intracellular recordings of ventrolatera...

journal_title：Experimental physiology

authors： Dutschmann M,Paton JF

更新日期：2003-11-01 00:00:00

abstract：:Power spectral analysis of heart rate variability has often been used to assess cardiac autonomic function; however, the relationship of low-frequency (LF) power of heart rate variability to cardiac sympathetic tone has been unclear. With or without adjustment for high-frequency (HF) power, total power or respiration,...

journal_title：Experimental physiology

authors： Goldstein DS,Bentho O,Park MY,Sharabi Y

更新日期：2011-12-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? This review describes the role of renal nerves as the key carrier of signals from the kidneys to the CNS and vice versa; the brain and kidneys communicate through this carrier to maintain homeostasis in the body. What advances does it highlight? Whether renal or autonomic ...

journal_title：Experimental physiology

authors： Nishi EE,Bergamaschi CT,Campos RR

更新日期：2015-04-20 00:00:00

abstract：:The present study examined whether an increase in leg blood flow and oxygen delivery at the onset of intense exercise would speed the rate of rise in leg oxygen uptake. Nine healthy men (25 ± 1 years old, mean ± SEM) performed one-leg knee-extensor exercise (62 ± 3 W, 86 ± 3% of incremental test peak power) for 4 min ...

journal_title：Experimental physiology

authors： Nyberg M,Christensen PM,Mortensen SP,Hellsten Y,Bangsbo J

更新日期：2014-10-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? This review provides a comprehensive overview of Nox5 from basic biology to human disease and highlights unique features of this Nox isoform What advances does it highlight? Major advances in Nox5 biology relate to crystallization of the molecule and new insights into the ...

journal_title：Experimental physiology

authors： Touyz RM,Anagnostopoulou A,Rios F,Montezano AC,Camargo LL

更新日期：2019-05-01 00:00:00

abstract：:It is unclear whether measurement of limb or conduit artery blood flow during recovery from exercise provides an accurate representation of flow to the muscle capillaries where gas exchange occurs. To investigate this, we: (a) examined the kinetic responses of femoral artery blood flow (QFA), estimated muscle capillar...

journal_title：Experimental physiology

authors： Harper AJ,Ferreira LF,Lutjemeier BJ,Townsend DK,Barstow TJ

更新日期：2008-10-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Regulation of cardiac function is typically achieved by changes in heart rate (HR) and cardiac shortening velocity (strain rate; SR), but their interdependence in vivo remains poorly understood. What is the main finding and its importance? Using resistance exerci...

journal_title：Experimental physiology

authors： Stöhr EJ,Stembridge M,Esformes JI

更新日期：2015-04-20 00:00:00

abstract：:What is the central question of this study? Myocardial ischaemia-reperfusion (I/R) injury causes interference in the systemic circulation and damages not only the heart but also several vital organs, including the brain. Recently, a novel peptide called humanin has been shown to exert potent neuroprotective effects. H...

journal_title：Experimental physiology

authors： Kumfu S,Charununtakorn ST,Jaiwongkam T,Chattipakorn N,Chattipakorn SC

更新日期：2016-06-01 00:00:00

abstract：:The effects of exogenous arginine vasotocin (AVT), isotocin (IT) and melatonin on the blood pressure of conscious Atlantic cod (Gadus morhua) were examined. Ventral aortic blood pressure (PVA) was recorded from a cannula inserted into the afferent branchial artery of the third gill arch. Dorsal aortic blood pressure (...

journal_title：Experimental physiology

authors： Kulczykowska E

更新日期：1998-11-01 00:00:00