Abstract:
:Human platelet/endothelial cell adhesion molecule-1 (PECAM1), an important member of the immunoglobulin gene superfamily, is widely distributed on cells of the vascular system and mediates cellular interactions through both homophilic and heterophilic adhesive mechanisms. The function of PECAM1 in vitro has begun to be understood, but its function in vivo is yet to be established. To study the function of PECAM1 in vivo, its mouse counterpart was identified and its cDNA gene isolated and characterized. In this study, the mouse chromosomal localization was determined for the mouse gene encoding Pecam. Fluorescence in situ hybridization was used to map the Pecam gene on mouse chromosome 6, region F3-G1.
journal_name
Genomicsjournal_title
Genomicsauthors
Xie Y,Muller WAdoi
10.1006/geno.1996.0546subject
Has Abstractpub_date
1996-10-15 00:00:00pages
226-8issue
2eissn
0888-7543issn
1089-8646pii
S0888-7543(96)90546-7journal_volume
37pub_type
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