Effects of various peptides on isolated rabbit lower esophageal sphincter.

abstract：:Higher levels of natriuretic peptides were identified in outpatients after myocardial infarction (MI) compared to the healthy population, even in the absence of heart failure (HF). Therefore, we assessed the optimal cut-off value of B-type natriuretic peptide (BNP) in relation to new-onset HF prediction in 79 post-MI ...

journal_title：Peptides

authors： Radovanovic M,Vasiljevic Z,Radovanovic N,Marinkovic J,Beleslin B,Mitrovic P,Stankovic S,Stankovic G

更新日期：2010-10-01 00:00:00

abstract：:The present status of our understanding of the feedback regulation of pancreatic secretion by peptide YY (PYY) released from the distal intestine is reviewed. Exocrine pancreatic secretion is primarily controlled by the cephalic (the vagus nerve), gastric (acid and pepsin secretion, and nutrients delivered into the du...

journal_title：Peptides

authors： Naruse S,Kitagawa M,Ishiguro H,Hayakawa T

更新日期：2002-02-01 00:00:00

abstract：:Gastric inhibitory polypeptide (GIP) is a 42-amino acid peptide, belonging to the VIP-secretin-glucagon superfamily, some members of this group are able to regulate adrenocortical function. GIP-receptor mRNA has been detected in the rat adrenal cortex, but investigations on the effect of GIP on steroid-hormone secreti...

journal_title：Peptides

authors： Mazzocchi G,Rebuffat P,Meneghelli V,Malendowicz LK,Tortorella C,Gottardo G,Nussdorfer GG

更新日期：1999-01-01 00:00:00

abstract：:The proteolytic conversion of oxytocin and vasopressin by purified rat brain synaptic membranes was studied at 37 degrees C and physiological pH 7.4. The formed peptide fragments were isolated by high performance liquid chromatography and characterized by amino acid analysis. When oxytocin was incubated with synaptic ...

journal_title：Peptides

authors： Stancampiano R,Melis MR,Argiolas A

更新日期：1991-09-01 00:00:00

abstract：:We have previously shown that brief, vena caval infusion of gastrin-releasing peptide1-27 (GRP), delivered shortly (5 min) after the end of the first spontaneous nocturnal meal, significantly prolongs the postprandial intermeal interval (IMI) without affecting the size of the subsequent meal in freely-feeding rats. In...

journal_title：Peptides

authors： Rushing PA,Gibbs J

更新日期：1998-01-01 00:00:00

abstract：:The presence of the proenkephalin A-derived peptide Met5-enkephalin-Arg6-Gly7-Leu8 was demonstrated throughout the human gastrointestinal tract. Highest concentrations of Met5-enkephalin-Arg6-Gly7-Leu8, as assessed by radioimmunoassay, were measured in the separated muscularis externa, while lower levels were found in...

journal_title：Peptides

authors： Ferri GL,Morreale RA,Dockray GJ

更新日期：1986-09-01 00:00:00

abstract：:Urotensin II (UII), first identified from goby urophysis, is a potent vasoactive peptide hormone and an endogenous ligand for an orphan G protein-coupled receptor GPR14, now named urotensin II receptor (UT-R). In addition to its vascular actions, UII has been shown to have mitogenic effects on tumor growth and some re...

journal_title：Peptides

authors： Morimoto R,Satoh F,Murakami O,Totsune K,Arai Y,Suzuki T,Sasano H,Ito S,Takahashi K

更新日期：2008-05-01 00:00:00

abstract：:Since its discovery, many physiologic functions have been ascribed to ghrelin, a gut derived hormone. The presence of a median fatty acid side chain on the ghrelin peptide is required for the binding and activation of the classical ghrelin receptor, the growth hormone secretagogue receptor (GHSR)-1a. Ghrelin O-acyl tr...

journal_title：Peptides

authors： Al Massadi O,Tschöp MH,Tong J

更新日期：2011-11-01 00:00:00

abstract：:We studied the effects of calcitonin gene-related peptide (CGRP) on ciliary beat frequency (CBF) and electrical properties of canine tracheal epithelium by a photoelectric method and Ussing's short-circuit technique, respectively. CGRP dose dependently increased CBF, an effect that was accompanied by elevation of intr...

journal_title：Peptides

authors： Tamaoki J,Kanemura T,Kobayashi K,Sakai N,Takizawa T

更新日期：1989-09-01 00:00:00

abstract：:Nonmammalian peptides of the tachykinin, bombesin and opioid families, injected into the brain ventricles, potently and specifically affect drinking behaviour of rats and pigeons. These peptides, or at least their counterparts, have been found in the brain of mammals and birds. It has been hypothesized that these endo...

journal_title：Peptides

authors： de Caro G,Massi M

更新日期：1985-01-01 00:00:00

abstract：:The C-terminus of the transcription factor p53 seems to play an important role by controlling the specific DNA-binding activity, which is directly associated with sensing damaged DNA. Another region located in the N-terminus of the protein has also been shown to regulate the DNA-binding activity of the protein. This a...

journal_title：Peptides

authors： Portefaix JM,Rio MD,Granier C,Roquet F,Pau B,Navarro-Teulon I

更新日期：2003-03-01 00:00:00

abstract：:Urotensin II (U-II) is a vasoactive peptide with many potent effects in the cardiorenovascular system. U-II activates a G-protein-coupled receptor termed UT. UT and U-II are highly expressed in the cardiovascular and renal system. Patients with various cardiovascular diseases show high U-II plasma levels. It was demon...

journal_title：Peptides

authors： Tölle M,van der Giet M

更新日期：2008-05-01 00:00:00

abstract：:Angiotensin(1-7) had a compound effect on blood pressure of pithed Sprague-Dawley rats. The initial phase of the response consisted of an increase in MAP of short duration and independent of injected dose, followed by a decline of arterial pressure to values below baseline. Both the magnitude (range: -4 +/- 1 to -13 +...

journal_title：Peptides

authors： Benter IF,Diz DI,Ferrario CM

更新日期：1993-07-01 00:00:00

abstract：:The somatostatin analogs D-Phe-Cys-D-Trp-Lys-Thr-Cys-Thr and the corresponding penicillamine compounds have been prepared and tested for their ability to displace [3H]naloxone and [3H] [D-Ala2, D-Leu5]enkephalin from rat brain receptors. While somatostatin and the cystine containing peptide displayed little or no pref...

journal_title：Peptides

authors： Pelton JT,Gulya K,Hruby VJ,Duckles S,Yamamura HI

更新日期：1985-01-01 00:00:00

abstract：:CR 1409, a glutaramic acid derivative with competitive cholecystokinin-antagonistic activity, was administered IP and evaluated in comparison with proglumide (the model CCK-receptor antagonist), gabexate (protease inhibitor) and PGE2 (cytoprotective) on two different models of experimental pancreatitis. Acute pancreat...

journal_title：Peptides

authors： Makovec F,Bani M,Cereda R,Chistè R,Revel L,Rovati LC,Setnikar I,Rovati LA

更新日期：1986-11-01 00:00:00

abstract：:Although previous studies have implicated NPY in the etiology of experimental cancer anorexia, the results have been difficult to interpret. Studies have suggested that although NPY level and message were decreased in the dorsomedial hypothalamic area (DMA), they were elevated in the ventromedial hypothalamic area (VM...

journal_title：Peptides

authors： Chance WT,Xiao C,Dayal R,Sheriff S

更新日期：2007-02-01 00:00:00

abstract：:Are ACTH and insulin synthesized in tissues other than the pituitary and pancreas, respectively? ACTH and TSH are widely distributed in the rat brain but are restricted to the hypothalamic regions of the primate brain. It is concluded that these pituitary peptides are not synthesized in the brain in extrahypothalamic ...

journal_title：Peptides

authors： Yalow RS,Eng J

更新日期：1981-01-01 00:00:00

abstract：:The in vitro activity of six polycationic peptides, buforin II, cecropin P1, indolicidin, magainin II, nisin, and ranalexin, were evaluated against several clinical isolates of gram-positive and gram-negative aerobic bacteria, yeasts, Pneumocystis carinii and Cryptosporidium parvum, by using microbroth dilution method...

journal_title：Peptides

authors： Giacometti A,Cirioni O,Barchiesi F,Del Prete MS,Scalise G

更新日期：1999-11-01 00:00:00

abstract：:Using a biologically active radioligand, [Tyr(125I)10]VIP, we have identified and characterized receptors for vasoactive intestinal peptide (VIP) on membranes prepared from the rat superior mesenteric artery and bovine coronary arteries. Binding was specific, saturable, reversible and dependent on time and temperature...

journal_title：Peptides

authors： Huang M,Rorstad OP

更新日期：1987-05-01 00:00:00

abstract：:The Manduca allatotropin (Mas-AT) gene is expressed as at least three mRNA isoforms that differ from each other by alternative splicing. The location at which the alternative exons are included in the mature mRNAs occur within the open reading frame, so that three different propeptides are predicted as translation pro...

journal_title：Peptides

authors： Horodyski FM,Bhatt SR,Lee KY

更新日期：2001-02-01 00:00:00

abstract：:Elucidating how neuropeptides affect physiology may result in delineating peptidergic mechanisms and identifying antagonists for application in basic and translational science. Human neuropeptide Y (NPY) regulates cardiac activity; frequently invertebrates contain orthologs of vertebrate peptides. We report invertebra...

journal_title：Peptides

authors： Setzu M,Biolchini M,Lilliu A,Manca M,Muroni P,Poddighe S,Bass C,Angioy AM,Nichols R

更新日期：2012-02-01 00:00:00

abstract：:In this study we investigated the role that dopaminergic pathways play in the miotic effect exerted by neurotensin after intracameral administration. Neurotensin was injected into the anterior chamber (AC) at a dose of 30 micrograms to 4 groups of albino rabbits which had previously undergone the following treatment: ...

journal_title：Peptides

authors： Tassorelli C,Spampinato D,Caruso P,Cavaliere S,Micieli G,Drago F,Nappi G

更新日期：1990-11-01 00:00:00

abstract：:Expression of the two gonadotropin-releasing hormone homologue peptides GnRHI and GnRHII and their receptor GnRHR has been demonstrated in a number of malignancies. In hormone-dependent breast cancer, GnRH analogs are used for therapy in premenopausal women. Gene expression of GnRHI, II and R was studied in breast bio...

journal_title：Peptides

authors： Pazaitou-Panayiotou K,Chemonidou C,Poupi A,Koureta M,Kaprara A,Lambropoulou M,Constantinidis TC,Galaktidou G,Koffa M,Kiziridou A,Kakolyris S,Kolios G,Kortsaris A,Chatzaki E

更新日期：2013-04-01 00:00:00

abstract：:Neuropeptide Y (NPY) induces feeding in previously satiated animals after injection into the hypothalamus, especially the perifornical region (PFH). NPY also appears to have rewarding properties as evidenced by its ability to produce a conditioned place preference following injection into the nucleus accumbens (N.Acc)...

journal_title：Peptides

authors： Brown CM,Fletcher PJ,Coscina DV

更新日期：1998-01-01 00:00:00

abstract：:In this study, antimicrobial peptide S-thanatin (Ts) was chemically synthesized and linked to keyhole limpet hemocyanin (KLH) and bovine serum albumin (BSA) by carbodiimide reagent. Rabbits were immunized with Ts-KLH and polyclonal antibody against Ts was purified by fractional precipitation of ammonium sulfate, coupl...

journal_title：Peptides

authors： Wu G,Wang S,Wang X,Li X,Deng X,Shen Z,Xi T

更新日期：2011-07-01 00:00:00

abstract：:A novel protease inhibitor, designated mungoin, with both antifungal and antibacterial activities, and exhibiting a molecular mass of 10kDa in SDS-polyacrylamide gel electrophoresis, was isolated from mung bean (Phaseolus mungo) seeds. The isolation procedure involved a combination of extraction, ammonium sulfate prec...

journal_title：Peptides

authors： Wang S,Lin J,Ye M,Ng TB,Rao P,Ye X

更新日期：2006-12-01 00:00:00

abstract：:Human Zonulin, related to the Zonula occludens toxin of Vibrio cholerae, regulates intestinal permeability and is induced in inflammatory disorders of the lower GI tract. Gastroesophageal reflux disease (GERD) is associated with an impairment of epithelial barrier function. Here, we studied expression of zonulin in th...

journal_title：Peptides

authors： Wex T,Mönkemüller K,Kuester D,Fry L,Kandulski A,Malfertheiner P

更新日期：2009-06-01 00:00:00

abstract：:It has been proved that input of specific electroacupuncture (EA) can activate beta-endorphin(beta-EP)ergic and noradrenergic neurons projecting to the rostral ventrolateral medulla (RVL), the latter acting upon the RVL-GABAergic interneurons, thereby produce depressor effect. The present study further shows that: (1)...

journal_title：Peptides

authors： Ku YH,Chang YZ

更新日期：2001-09-01 00:00:00

abstract：:Two food-derived ACE inhibitory peptides, Ile-Pro-Pro (IPP) and Leu-Lys-Pro (LKP), may have potential as alternative treatments for treatment of mild- or pre-hypertension. Lack of stability to secretory and intracellular peptidases and poor permeability across intestinal epithelia are typical limiting factors of oral ...

journal_title：Peptides

authors： Gleeson JP,Heade J,Ryan SM,Brayden DJ

更新日期：2015-09-01 00:00:00

abstract：:HP-1 is the most abundant human representative of a recently discovered class of neutrophil cystine- and arginine-rich peptides. These peptides have many potentially regulatory activities expressed at nanomolar concentrations. To establish the levels of HP-1 that can accumulate in human lung tumors and nondiseased lun...

journal_title：Peptides

authors： Bateman A,Singh A,Jothy S,Fraser R,Esch F,Solomon S

更新日期：1992-01-01 00:00:00