Abstract:
:Possible effects of Chernobyl fallout on outcome of pregnancy in Finland were evaluated in a nationwide follow-up study. The outcomes were the rate of live births and stillbirths, pregnancy loss, and induced abortions by municipality. Exposure was assessed based on nationwide surveys of radiation dose rate from the Chernobyl fallout, from both external and internal exposures. Using these measurements, we estimated the monthly dose rate for each of the 455 Finnish municipalities. On average, the dose rate from Chernobyl fallout reached 50 microSv per month in May 1986--a doubling of the natural background radiation. In the most heavily affected area, 4 times the normal background dose rates were recorded. Given the underlying regional differences in live birth, stillbirth, and abortion rates, we used longitudinal analysis comparing changes over time within municipalities. A temporary decline in the live birth rate had already begun before 1986, with no clear relationship to the level of fallout. A statistically significant increase in spontaneous abortions with dose of radiation was observed. No marked changes in induced abortions or stillbirths were observed. The decrease in the live birth rate is probably not a biological effect of radiation, but more likely related to public concerns of the fallout. The effect on spontaneous abortions should be interpreted with caution, because of potential bias or confounding. Further, there is little support in the epidemiologic literature on effects of very low doses of radiation on pregnancy outcome.
journal_name
Environ Health Perspectjournal_title
Environmental health perspectivesauthors
Auvinen A,Vahteristo M,Arvela H,Suomela M,Rahola T,Hakama M,Rytömaa Tdoi
10.1289/ehp.01109179subject
Has Abstractpub_date
2001-02-01 00:00:00pages
179-85issue
2eissn
0091-6765issn
1552-9924pii
sc271_5_1835journal_volume
109pub_type
杂志文章abstract::Rats continuously exposed to NO2 at 0.04, 0.4, and 4.0 ppm for as long as 27 months were submitted to morphological observation and electronmicroscopic morphometry of the lung. At 4 ppm exposure for 9 months, bronchial epithelium showed typical proliferation, which progressed further at 18 months. At this stage, proli...
journal_title:Environmental health perspectives
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journal_title:Environmental health perspectives
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更新日期:2014-05-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章,随机对照试验
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更新日期:2009-08-01 00:00:00
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journal_title:Environmental health perspectives
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更新日期:1978-08-01 00:00:00
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journal_title:Environmental health perspectives
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更新日期:1996-12-01 00:00:00
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journal_title:Environmental health perspectives
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更新日期:1996-05-01 00:00:00
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doi:10.1289/ehp.99107823
更新日期:1999-10-01 00:00:00
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更新日期:2018-06-27 00:00:00
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journal_title:Environmental health perspectives
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更新日期:1979-08-01 00:00:00
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更新日期:2014-10-30 00:00:00
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更新日期:2002-07-01 00:00:00
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更新日期:1993-12-01 00:00:00
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journal_title:Environmental health perspectives
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更新日期:1983-02-01 00:00:00
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journal_title:Environmental health perspectives
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更新日期:2005-09-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/EHP167
更新日期:2016-09-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.792957
更新日期:1979-04-01 00:00:00
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更新日期:2009-05-01 00:00:00
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pub_type: 杂志文章
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journal_title:Environmental health perspectives
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更新日期:1986-04-01 00:00:00
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journal_title:Environmental health perspectives
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更新日期:2014-06-01 00:00:00
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journal_title:Environmental health perspectives
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更新日期:2006-04-01 00:00:00
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journal_title:Environmental health perspectives
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更新日期:1986-12-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章
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更新日期:2003-10-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2006-11-01 00:00:00
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journal_title:Environmental health perspectives
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更新日期:2017-02-01 00:00:00
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journal_title:Environmental health perspectives
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更新日期:1974-08-01 00:00:00