Prospects for xenotransplantation of the liver.

Abstract:

:Because of the tremendous success of clinical transplantation of the liver and other organs in the last three decades, the demand for organs for transplantation has risen sharply and there is now a substantial shortage. The utilization of organs from other species, xenotransplantation, is increasingly viewed as a potential solution to this problem. The major limitation to xenotransplantation is the formidable immunological barriers that prevent the successful transplantation of non-human organs into human recipients. Here we review current knowledge about the immunology of xenotransplantation and the limited clinical and experimental experience in xenotransplantation of the liver.

journal_name

J Hepatol

journal_title

Journal of hepatology

authors

Harland RC,Platt JL

doi

10.1016/s0168-8278(96)80082-1

subject

Has Abstract

pub_date

1996-08-01 00:00:00

pages

248-58

issue

2

eissn

0168-8278

issn

1600-0641

pii

S0168-8278(96)80082-1

journal_volume

25

pub_type

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