Two different dosages of yeast derived recombinant hepatitis B vaccines: a comparison of immunogenicity.

abstract：:Chagas' disease is a major tropical disease for which a cure for chronic phase does not exist yet. Trypanosoma cruzi trans-sialidase (TS) seems to be involved in relevant processes such as infectivity, host survival and, very importantly, disease pathogenesis. In this study, we show that mice vaccinated with an engine...

journal_title：Vaccine

authors： Fontanella GH,De Vusser K,Laroy W,Daurelio L,Nocito AL,Revelli S,Contreras R

更新日期：2008-05-02 00:00:00

abstract：BACKGROUND:The relative importance of different attitudes in predicting vaccination among healthcare personnel (HCP) is unclear. We hypothesized that HCP who feel at risk without vaccination or say they would regret not getting vaccinated would be more likely to get vaccinated than HCP who do not expect these emotional...

journal_title：Vaccine

authors： Thompson MG,Gaglani MJ,Naleway A,Ball S,Henkle EM,Sokolow LZ,Brennan B,Zhou H,Foster L,Black C,Kennedy ED,Bozeman S,Grohskopf LA,Shay DK

更新日期：2012-05-21 00:00:00

abstract：:Two live recombinant vaccines (Flc9 and Flc11) against classical swine fever (CSF) were evaluated for their capacity to reduce transmission of virulent CSF virus (CSFV) among vaccinated pigs. In Flc9 the 5' terminal half of the E2 gene of the C-strain, a CSFV vaccine strain, was exchanged with the homologous gene of t...

journal_title：Vaccine

authors： de Smit AJ,Bouma A,van Gennip HG,de Kluijver EP,Moormann RJ

更新日期：2001-01-08 00:00:00

abstract：:Thirty-two rhesus monkeys were used to evaluate the dose response of a recombinant HEV vaccine, and the efficacy of the vaccine based on the ORF2 protein of the Pakistani strain for pre- and post-exposure vaccination against intravenous challenge with homologous or heterologous virus was examined. Post-exposure vaccin...

journal_title：Vaccine

authors： Tsarev SA,Tsareva TS,Emerson SU,Govindarajan S,Shapiro M,Gerin JL,Purcell RH

更新日期：1997-12-01 00:00:00

abstract：:Most traditional vaccines are administered via the intramuscular route. Other routes of administration however, can induce equal or improved protective memory responses and might provide practical advantages such as needle-free immunization, dose sparing and induction of tissue-specific (mucosal) immunity. Here we exp...

journal_title：Vaccine

authors： van Aalst S,Jansen MAA,Ludwig IS,van der Zee R,van Eden W,Broere F

更新日期：2018-03-07 00:00:00

abstract：:Vaccines are everywhere hugely successful but are also under attack. The reason for the latter is the perception by some people that vaccines are unsafe. However that may be, vaccine safety, life any other scientific subject, must be constantly studied. It was from this point of view that a meeting was organized at th...

journal_title：Vaccine

authors： Plotkin SA,Offit PA,DeStefano F,Larson HJ,Arora NK,Zuber PLF,Fombonne E,Sejvar J,Lambert PH,Hviid A,Halsey N,Garçon N,Peden K,Pollard AJ,Markowitz LE,Glanz J

更新日期：2020-02-18 00:00:00

abstract：:The objectives of this study were to evaluate the effects of a therapeutic vaccine intervention with a modified-live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine on the dynamics of a heterologous viral infection in a population of pigs, and to determine the clinical and virological response of p...

journal_title：Vaccine

authors： Cano JP,Dee SA,Murtaugh MP,Pijoan C

更新日期：2007-05-30 00:00:00

abstract：:The prevalence of hepatitis B virus (HBV) infection and its sequelae vary widely in the different populations living in the Asian-Pacific region. Horizontal transmission plays an important role in the spread of the disease; in East Asia, however, maternal transmission is particularly significant since a high portion o...

journal_title：Vaccine

authors： Sung JL

更新日期：1990-03-01 00:00:00

abstract：:DNA vectors can be used to deliver vaccine antigens that stimulate effective protective immunity in mice, but in larger, outbred animal species, the protective efficacy is lower or large doses of DNA are required. These data demonstrate that porcine interleukin-3 (IL-3) when delivered to pigs by DNA vector or in low d...

journal_title：Vaccine

authors： Andrew M,Morris K,Coupar B,Sproat K,Oke P,Bruce M,Broadway M,Morrissy C,Strom D

更新日期：2006-04-12 00:00:00

abstract：BACKGROUND:IXIARO® is a Vero cell-derived, inactivated Japanese encephalitis (JE) vaccine licensed mainly in western countries for children and adults traveling to JE endemic areas. Limited immunogenicity and safety data in elderly travelers have been available. OBJECTIVES:To evaluate safety and immunogenicity of IXIA...

journal_title：Vaccine

authors： Cramer JP,Dubischar K,Eder S,Burchard GD,Jelinek T,Jilma B,Kollaritsch H,Reisinger E,Westritschnig K

更新日期：2016-08-31 00:00:00

abstract：BACKGROUND:Sexual mixing between heterogeneous population subgroups is an integral component of mathematical models of sexually transmitted infections (STIs). This study compares the fit of different mixing representations to survey data and the impact of different mixing assumptions on the predicted benefits of hypoth...

journal_title：Vaccine

authors： Easterly CW,Alarid-Escudero F,Enns EA,Kulasingam S

更新日期：2018-09-05 00:00:00

abstract：:Continuing investments in vaccine innovation are insufficiently translated into market entries of novel vaccines. This innovation paradox is in part caused by stakeholders lacking complete understanding of the complex array of steps necessary for vaccine development and collaboration difficulties between the wide vari...

journal_title：Vaccine

authors： Van de Burgwal LHM,Ribeiro CDS,Van der Waal MB,Claassen E

更新日期：2018-11-26 00:00:00

abstract：:In the present study, we investigated the duration of protection afforded to pigs immunized in two different prime-boost regimens: one is homologus priming and boosting with a protein vaccine, and the other is priming with a DNA vaccine and boosting with the protein vaccine. Groups of pigs that received the same vacci...

journal_title：Vaccine

authors： Guo YJ,Sun SH,Zhang Y,Chen ZH,Wang KY,Huang L,Zhang S,Zhang HY,Wang QM,Wu D,Zhu WJ

更新日期：2004-09-28 00:00:00

abstract：:Cholera is a potentially lethal diarrhea disease caused by the gram-negative bacterium Vibrio cholerae. The need for an effective cholera vaccine is clearly indicated but the challenges of eliciting both systemic and mucosal immune responses remains a significant challenge. In the current report, we discovered that a ...

journal_title：Vaccine

authors： Xu G,Wang S,Zhuang L,Hackett A,Gu L,Zhang L,Zhang C,Wang H,Huang Z,Lu S

更新日期：2009-06-12 00:00:00

abstract：:Human pythiosis is an emerging disease in the tropical, subtropical and temperate regions of the world. It is caused by the straminipilan, fungus-like, aquatic organism Pythium insidiosum. Pythiosis occurs in localized as well as systemic or vascular forms. Most patients with arterial pythiosis usually have underlying...

journal_title：Vaccine

authors： Wanachiwanawin W,Mendoza L,Visuthisakchai S,Mutsikapan P,Sathapatayavongs B,Chaiprasert A,Suwanagool P,Manuskiatti W,Ruangsetakit C,Ajello L

更新日期：2004-09-09 00:00:00

abstract：:The conventional egg-grown influenza vaccines are trivalent. To test the feasibility of using multivalent influenza virus-like particles (VLPs) as an alternative influenza vaccine, we developed cell-derived influenza VLPs containing the hemagglutinin (HA) of the H1 subtype virus A/PR/8/34 or the H3 subtype virus A/Aic...

journal_title：Vaccine

authors： Quan FS,Steinhauer D,Huang C,Ross TM,Compans RW,Kang SM

更新日期：2008-06-19 00:00:00

abstract：:Designation as a Category B biothreat agent has propelled Coxiella burnetii from a relatively obscure, underappreciated, "niche" microorganism on the periphery of bacteriology, to one of possibly great consequence if actually used in acts of bioterrorism. Advances in the study of this microorganism proceeded slowly, p...

journal_title：Vaccine

authors： Waag DM

更新日期：2007-10-16 00:00:00

abstract：:Europe is not ready for the next pandemic. Nonetheless, several positive developments are cause for optimism. The European Centre for Disease Control (ECDC) was founded in May 2005 and has explicitly identified influenza as one of its top four priorities. Europe is also taking steps to streamline the regulatory approv...

journal_title：Vaccine

authors：

更新日期：2006-11-10 00:00:00

abstract：BACKGROUND:It is known that antineoplastic treatment may induce secondary immunodeficiency, but studies after childhood sarcoma are rare. Since 1998, the Late Effects Surveillance System (LESS) of the German Society for Paediatric Oncology and Haematology (GPOH) prospectively registers late effects in soft tissue-, ost...

journal_title：Vaccine

authors： Paulides M,Stöhr W,Laws HJ,Graf N,Lakomek M,Berthold F,Schmitt K,Niggli F,Jürgens H,Bielack S,Koscielniak E,Klingebiel T,Langer T

更新日期：2011-02-11 00:00:00

abstract：:The number of vaccines available and included as part of the national immunization schedules, has increased significantly over the past few decades. This impacts on patient/parent compliance and creates a challenge for health care providers for implementation of schedules necessitating training and infrastructure impr...

journal_title：Vaccine

authors： Visser A,Hoosen A

更新日期：2012-09-07 00:00:00

abstract：:Interest in addressing antimicrobial resistance (AMR) has grown recently but little effort has been made to consider how existing and new vaccines could impact on AMR. A 2017 Chatham House meeting considered the role of vaccines and how to demonstrate their value through their impact on AMR. Ways existing vaccines hav...

journal_title：Vaccine

authors： Clift C,Salisbury DM

更新日期：2017-12-04 00:00:00

abstract：:Hepatitis A and B are common infections worldwide and their severity is related to the individual's age upon initial infection. Furthermore, when hepatitis B infection occurs in infants, the risk of becoming a chronic carrier is 90%. For hepatitis A, the lower incidence of disease arising from an improvement in living...

journal_title：Vaccine

authors： Van Damme P,Van der Wielen M

更新日期：2001-03-21 00:00:00

abstract：:Recombinant canarypox (CP) and fowlpox (FP) viruses that contained two forms of the HIV-1 (SF2 strain) env gene were engineered and their expression analysed in chick, simian and human cells. These vectors can efficiently replicate in avian but not in mammalian cells, in which infection is abortive. The two forms, con...

journal_title：Vaccine

authors： Radaelli A,De Giuli Morghen C

更新日期：1994-09-01 00:00:00

abstract：:Oral, replication-competent Ad-HIV vaccines are advancing to human trials. Previous evaluation of protective efficacy in non-human primates has primarily followed upper respiratory tract administrations. Here we compared sequential oral (O/O) versus intranasal/oral (I/O) priming of rhesus macaques with Ad5 host range ...

journal_title：Vaccine

authors： Zhou Q,Hidajat R,Peng B,Venzon D,Aldrich MK,Richardson E,Lee EM,Kalyanaraman VS,Grimes G,Gómez-Román VR,Summers LE,Malkevich N,Robert-Guroff M

更新日期：2007-11-19 00:00:00

abstract：:Funded immunization programs are best able to achieve high participation rates, optimal protection of the target population, and indirect protection of others. However, in many countries public funding of approved vaccines can be substantially delayed, limited to a portion of the at-risk population or denied altogethe...

journal_title：Vaccine

authors： Scheifele DW,Ward BJ,Halperin SA,McNeil SA,Crowcroft NS,Bjornson G

更新日期：2014-02-07 00:00:00

abstract：INTRODUCTION:Widespread introduction of pneumococcal conjugated vaccines (PCVs) impacted on invasive pneumococcal disease (IPD). However, IPD reduction may not be similar in all outcomes within IPD. We assessed PCV7/PCV13 impact on pneumococcal meningitis, bacteremic pneumonia (BP) and other (non-meningitis, non-pneumo...

journal_title：Vaccine

authors： Ben-Shimol S,Givon-Lavi N,Grisaru-Soen G,Megged O,Greenberg D,Dagan R,Israel Bacteremia and Meningitis Active Surveillance Group.

更新日期：2018-08-28 00:00:00

abstract：:The aims of this project were: (1) to determine the extent to which infant hepatitis B immunisation is preventing chronic hepatitis B infection in children living in a sample of Pacific Island countries; and (2) to identify factors associated with the successful prevention of hepatitis B infection in these populations...

journal_title：Vaccine

authors： Wilson N,Ruff TA,Rana BJ,Leydon J,Locarnini S

更新日期：2000-07-01 00:00:00

abstract：:First year medical students at an allopathic medical school regional campus were asked to complete a 10-question survey at both the beginning and the conclusion of a required course on immunology, hematology and oncology. The survey was designed to solicit student attitudes about vaccination and the students' level of...

journal_title：Vaccine

authors： Onello E,Friedrichsen S,Krafts K,Simmons G Jr,Diebel K

更新日期：2020-01-22 00:00:00

abstract：:Despite extensive research, no unifying concept has satisfactorily explained the cause of the sudden infant death syndrome (SIDS). The details are briefly outlined of some of the evidence supporting the hypothesis that common bacterial toxins are important in the aetiology of SIDS. These bacterial toxins act as trigge...

journal_title：Vaccine

authors： Murrell TG,Murrell WG,Lindsay JA

更新日期：1994-03-01 00:00:00

abstract：:It is accepted that booster vaccinations of chickens with live Salmonella vaccines are essential part of vaccinations schemes to induce an effective adaptive immune response. As manufacturer of registered live Salmonella vaccines recommend different times of booster the question raises whether the duration between the...

journal_title：Vaccine

authors： Methner U

更新日期：2018-05-17 00:00:00