Impact of a modified-live porcine reproductive and respiratory syndrome virus vaccine intervention on a population of pigs infected with a heterologous isolate.

abstract：:Although concerns about safety of influenza vaccination during pregnancy have been raised in the past, vaccination of pregnant women was recommended in many countries during the 2009 A/H1N1 pandemic influenza. A retrospective cohort study was conducted to evaluate the risk of adverse maternal, fetal and neonatal outco...

journal_title：Vaccine

authors： Fabiani M,Bella A,Rota MC,Clagnan E,Gallo T,D'Amato M,Pezzotti P,Ferrara L,Demicheli V,Martinelli D,Prato R,Rizzo C

更新日期：2015-05-05 00:00:00

abstract：:The screening of common genetic polymorphisms among candidate genes for AIDS pathology in HIV exposed cohort populations has led to the description of 20 AIDS restriction genes (ARGs), variants that affect susceptibility to HIV infection or to AIDS progression. The combination of high-throughput genotyping platforms a...

journal_title：Vaccine

authors： Hutcheson HB,Lautenberger JA,Nelson GW,Pontius JU,Kessing BD,Winkler CA,Smith MW,Johnson R,Stephens R,Phair J,Goedert JJ,Donfield S,O'Brien SJ

更新日期：2008-06-06 00:00:00

abstract：:The membrane proximal region (MPR) of HIV-1 gp41 is a desirable target for development of a vaccine that elicits neutralizing antibodies since the patient-derived monoclonal antibodies, 2F5 and 4E10, bind to the MPR and neutralize primary HIV isolates. The 2F5 and 4E10 antibodies cross-react with lipids and structural...

journal_title：Vaccine

authors： Watson DS,Szoka FC Jr

更新日期：2009-07-23 00:00:00

abstract：:There is an emerging interest to develop human vaccines against medically-important fungal pathogens and a need for a preclinical animal model to assess vaccine efficacies and protective correlates. HLA-DR4 (DRB1∗0401 allele) transgenic mice express a human major histocompatibility complex class II (MHC II) receptor i...

journal_title：Vaccine

authors： Hurtgen BJ,Castro-Lopez N,Jiménez-Alzate MDP,Cole GT,Hung CY

更新日期：2016-10-17 00:00:00

abstract：:The correlation between the antigen content of inactivated Newcastle disease (ND) oil emulsion-vaccines and the serological response after immunisation was studied. The haemagglutinin-neuraminidase (HN) and fusion (F) proteins of Newcastle disease virus (NDV) were quantified in 33 inactivated oil-adjuvanted ND vaccine...

journal_title：Vaccine

authors： Maas RA,Komen M,van Diepen M,Oei HL,Claassen IJ

更新日期：2003-07-04 00:00:00

abstract：:Since 2004, general varicella vaccination has been recommended for all children 11-14 months of age in Germany. The objective of this study was to examine vaccination coverage in children and factors associated with parental acceptance during the first years after recommendation. In a regional surveillance area, cross...

journal_title：Vaccine

authors： Streng A,Seeger K,Grote V,Liese JG

更新日期：2010-08-09 00:00:00

abstract：:Intranasal (i.n.) vaccination of mice with three doses of 40 microg of rRV stimulated low anti-ricin ELISA and neutralizing antibody responses, which were only marginally protective against aerosol-delivered 5-10 LD(50) of ricin toxin. To enhance the protection, and to reduce the lung injury of vaccinated mice that su...

journal_title：Vaccine

authors： Kende M,Tan X,Wlazlowski C,Williams R,Lindsey C,Del Giudice G

更新日期：2007-04-20 00:00:00

abstract：:The measurement of measles-specific neutralizing antibodies, directed against the surface measles virus hemagglutinin and fusion proteins, is considered the gold standard in measles serology. We assessed functional measles-specific neutralizing antibody levels in a racially diverse cohort of 763 young healthy adolesce...

journal_title：Vaccine

authors： Haralambieva IH,Ovsyannikova IG,O'Byrne M,Pankratz VS,Jacobson RM,Poland GA

更新日期：2011-06-15 00:00:00

abstract：:Even though schistosomicidal agents and other control measures, including public hygiene and snail control exist, development of an efficacious vaccine still remains the most potentially powerful method for control of schistosomiasis. In our continuing efforts to develop a vaccine against schistosomiasis, we have sele...

journal_title：Vaccine

authors： Siddiqui AA,Pinkston JR,Quinlin ML,Saeed Q,White GL,Shearer MH,Kennedy RC

更新日期：2005-02-10 00:00:00

abstract：:Varied doses of Taishan Pinus massoniana pollen polysaccharide (TPPPS) and Astragalus polysaccharide (APS) extracted by hot water extraction and ethanol precipitation method were added to the vaccine in order to prepare polysaccharide-rabbit haemorrhagic disease (RHD) tissue inactivated vaccine. The purpose was to stu...

journal_title：Vaccine

authors： Wei K,Sun Z,Yan Z,Tan Y,Wang H,Zhu X,Wang X,Sheng P,Zhu R

更新日期：2011-03-21 00:00:00

abstract：:Clinical and serum antibody responses following intramuscular injection of two formulations of Salmonella typhi Vi capsular polysaccharide (Vi) were assessed in a double-blind evaluation. Healthy adults were randomly assigned to receive a 25 micrograms dose of liquid (Vi-Liq; n = 182) or freeze-dried Vi vaccine (Vi-Ly...

journal_title：Vaccine

authors： Keitel WA,Bond NL,Zahradnik JM,Cramton TA,Robbins JB

更新日期：1994-01-01 00:00:00

abstract：:Whole killed meningococci (Nm) and pertussis bacteria (Bp) were tested for mucosal immunogenicity and as mucosal adjuvants for an inactivated influenza virus vaccine given intranasally to unanaesthetized mice. Virus was given alone, or simply mixed with one of the bacterial preparations, in four doses at weekly interv...

journal_title：Vaccine

authors： Berstad AK,Andersen SR,Dalseg R,Dromtorp S,Holst J,Namork E,Wedege E,Haneberg B

更新日期：2000-03-17 00:00:00

abstract：:Inactivated influenza vaccine is recommended for routine use in high-risk individuals in the United States, including women who will be in the second or third trimesters of pregnancy. The basis for this recommendation is the high risk of exposure and disease due to influenza viruses in pregnant women, as well as the i...

journal_title：Vaccine

authors： Englund JA

更新日期：2003-07-28 00:00:00

abstract：:Hepatitis B (HB) immunization was introduced as part of the expanded programme on immunization (EPI) in two provinces in Thailand and evaluated over a four year period. Three doses of HB vaccine were offered to 60,980 newborns at birth, 2 and 6 months of age. The overall coverage for complete HB immunization was 90.4%...

journal_title：Vaccine

authors： Chunsuttiwat S,Biggs BA,Maynard J,Thamapalo S,Laoboripat S,Bovornsin S,Charanasri U,Pinyowiwat W,Kunasol P

更新日期：1997-04-01 00:00:00

abstract：:Helicobacter pylori infection can cause gastritis, peptic ulcer and can lead to gastric cancer. Lengthy antibiotic therapy does not protect the host against reinfection. H. pylori evolved to evade the recognition of the immune response by modifying several of its components whose orthologous proteins from other bacter...

journal_title：Vaccine

authors： Mori J,Vranac T,Smrekar B,Cernilec M,Serbec VČ,Horvat S,Ihan A,Benčina M,Jerala R

更新日期：2012-08-31 00:00:00

abstract：BACKGROUND:Protein-polysaccharide conjugate vaccines such as Haemophilus influenzae type b (Hib), meningococcal, and pneumococcal vaccine, induce immunological memory and longer lasting protection than plain polysaccharide vaccines. The most common proteins used as carriers are tetanus toxoid (TT) and cross reacting ma...

journal_title：Vaccine

authors： Voysey M,Sadarangani M,Clutterbuck E,Bolgiano B,Pollard AJ

更新日期：2016-07-25 00:00:00

abstract：:The effectiveness of HPV vaccine against HSIL+ (pathologically diagnosed CIN2+) in the first cohort in Japan was investigated in 22,743 women aged 20 to 29 years (parts of national cervical cancer screening program of FY [fiscal year] 2015, the Japan Cancer Society). Vaccinated women had a statistically significant 69...

journal_title：Vaccine

authors： Konno R,Konishi H,Sauvaget C,Ohashi Y,Kakizoe T

更新日期：2018-12-18 00:00:00

abstract：:Despite the availability of anti-microbial agents effective against Neisseria meningitidis, meningococcal disease continues to be a major global health problem, particularly in the very young. Serogroup A meningococci cause large epidemics in sub-Saharan Africa, whilst serogroups B and C organisms are responsible for ...

journal_title：Vaccine

authors： Borrow R,Balmer P,Miller E

更新日期：2005-03-18 00:00:00

abstract：:The live bacterial vaccine Mycobacterium bovis BCG (BCG) is a vehicle worth noticing for various protective antigens. The gene encoding the B-cell epitope of the oligopeptide repeating in the circumsporozoite protein (C.S. protein) of the rodent malaria parasite, Plasmodium yoelii, was inserted into the plasmid vector...

journal_title：Vaccine

authors： Matsumoto S,Yanagi T,Ohara N,Wada N,Kanbara H,Yamada T

更新日期：1996-01-01 00:00:00

abstract：:We have evaluated in C57/Bl6 and HLA-A2.1 transgenic mice the immunogenicity of three MVA vectors expressing either native HCV E1E2 polyprotein, truncated and secreted E1 (E'1(311)) and E2 (E'2(661)) proteins, or a chimeric E1E2 heterodimer presented at the plasma membrane. Immunization induced mainly a Th1 response i...

journal_title：Vaccine

authors： Abraham JD,Himoudi N,Kien F,Berland JL,Codran A,Bartosch B,Baumert T,Paranhos-Baccala G,Schuster C,Inchauspé G,Kieny MP

更新日期：2004-09-28 00:00:00

abstract：:It is of paramount importance to know the vaccination status in internationally adopted children, so that they can be correctly immunized. This study ascertains the seroprotection rate for vaccine-preventable diseases and the validity of the immunization cards in 637 adopted children. The absence of the immunization c...

journal_title：Vaccine

authors： Cilleruelo MJ,de Ory F,Ruiz-Contreras J,González-González R,Mellado MJ,García-Hortelano M,Villota J,García-Ascaso M,Piñeiro R,Martín-Fontelos P,Herruzo R

更新日期：2008-10-29 00:00:00

abstract：:We show here that the immunogenicity of the Modified Vaccinia Ankara MVA vaccine strain can be improved by deletion of the A35 gene, without diminishing the ability of the virus to replicate. Deletion of the A35 gene resulted in increased virus-specific immunoglobulin production, class switching to IgG isotypes, and v...

journal_title：Vaccine

authors： Rehm KE,Roper RL

更新日期：2011-04-12 00:00:00

abstract：BACKGROUND:To support vaccine decision-making we estimated from the societal perspective the potential health impact and costs averted through immunization with three vaccines - Haemophilus influenzae type b (Hib), pneumococcal conjugate vaccine (PCV) and rotavirus vaccine (RVV). METHODS:Based on variability in diseas...

journal_title：Vaccine

authors： Constenla D,Liu T

更新日期：2019-12-10 00:00:00

abstract：:As part of a larger study exploring how European citizens' balance issues of public and private interest and the extent to which they are prepared to accept State intervention on a range of public health issues, focus group participants were asked whether childhood immunisation should be a matter of parental choice or...

journal_title：Vaccine

authors： Moran N,Shickle D,Richardson E

更新日期：2008-01-17 00:00:00

abstract：:Non-pathogenic lactic acid bacteria (LAB) are attractive as live carriers to deliver protective antigens to the mucosal immune system. Both persisting and non-persisting strains of lactic acid bacteria have been evaluated and seem to work equally well by the systemic and nasal routes of administration. However, it is ...

journal_title：Vaccine

authors： Grangette C,Müller-Alouf H,Geoffroy M,Goudercourt D,Turneer M,Mercenier A

更新日期：2002-09-10 00:00:00

abstract：:The efficacy of antibody immunity against Streptococcus pneumoniae stems from the ability of opsonic, serotype (ST)-specific antibodies to pneumococcal capsular polysaccharide (PPS) to facilitate killing of the homologous ST by host phagocytes. However, PPS-specific antibodies have been identified that are protective ...

journal_title：Vaccine

authors： Fabrizio K,Manix C,Tian H,van Rooijen N,Pirofski LA

更新日期：2010-11-03 00:00:00

abstract：:Meat contamination by Salmonella spp. is emerging as a major cause of human enteric infections in industrialized countries. The attempts to reduce human cases of salmonellosis encompass pre- and post-harvest interventions. In this context, vaccination of pigs may represent an effective instrument in eliminating/reduci...

journal_title：Vaccine

authors： Pesciaroli M,Gradassi M,Martinelli N,Ruggeri J,Pistoia C,Raffatellu M,Magistrali CF,Battistoni A,Pasquali P,Alborali GL

更新日期：2013-06-12 00:00:00

abstract：:Mice immunized with plasmid DNA encoding Nef regulatory protein of human immunodeficiency virus type 1 developed high levels of anti-Nef antibodies. After 4 intramuscular injections of 100 microg plasmid DNA, anti-Nef antibodies reached titers up to 2 x 10(4). A significant specific antibody response was maintained fo...

journal_title：Vaccine

authors： Moureau C,Moynier M,Kavsan V,Montagnier L,Bahraoui E

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Vaccination coverage in Bosnia and Herzegovina has been declining over recent years. A World Health Organization Tailoring Immunization Programmes (TIP) project is underway to gain insights into the underlying reasons for this, to develop tailored interventions. As part of TIP, this study aimed to investigat...

journal_title：Vaccine

authors： Musa S,Skrijelj V,Kulo A,Habersaat KB,Smjecanin M,Primorac E,Becirovic D,Jackson C

更新日期：2020-02-18 00:00:00

abstract：INTRODUCTION:HPV vaccine uptake is lowest among young adults. Little is known about the most effective way to decrease missed opportunities (MO) and increase uptake of the vaccine in this vulnerable population. OBJECTIVES:To determine the impact of a clinical intervention bundle on the rate of MO and uptake of the vac...

journal_title：Vaccine

authors： Deshmukh U,Oliveira CR,Griggs S,Coleman E,Avni-Singer L,Pathy S,Shapiro ED,Sheth SS

更新日期：2018-06-14 00:00:00