Porcine interleukin-3 enhances DNA vaccination against classical swine fever.

abstract：:Reconstituted influenza virus (A/PR/8 strain) envelopes (RIVE) and influenza virus (A/Sichuan/87 (H3N2) strain) surface antigens were entrapped in dehydration-rehydration vesicles (DRV liposomes) composed of egg phosphatidylcholine (PC) or distearoyl phosphatidylcholine (DSPC DRV) and equimolar (32 mumol) cholesterol....

journal_title：Vaccine

authors： Gregoriadis G,Tan L,Ben-Ahmeida ET,Jennings R

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Sexual mixing between heterogeneous population subgroups is an integral component of mathematical models of sexually transmitted infections (STIs). This study compares the fit of different mixing representations to survey data and the impact of different mixing assumptions on the predicted benefits of hypoth...

journal_title：Vaccine

authors： Easterly CW,Alarid-Escudero F,Enns EA,Kulasingam S

更新日期：2018-09-05 00:00:00

abstract：:Despite antiretroviral medications, the rate of pediatric HIV-1 infections through breast-milk transmission has been staggering in developing countries. Therefore, the development of a vaccine to protect vulnerable infant populations should be actively pursued. We previously demonstrated that oral immunization of newb...

journal_title：Vaccine

authors： Marthas ML,Van Rompay KK,Abbott Z,Earl P,Buonocore-Buzzelli L,Moss B,Rose NF,Rose JK,Kozlowski PA,Abel K

更新日期：2011-04-12 00:00:00

abstract：:Japanese encephalitis is a major cause of encephalitis in Asia. Cases occur largely in rural areas of the South and East Asian region resulting in significant morbidity and mortality. Multiple vaccines exist to control Japanese encephalitis, but all suffer from problems. Envelope protein domain III of Japanese encepha...

journal_title：Vaccine

authors： Verma SK,Kumar S,Gupta N,Vedi S,Bhattacharya SM,Lakshmana Rao PV

更新日期：2009-11-16 00:00:00

abstract：BACKGROUND:Two conserved pneumococcal proteins, pneumolysin toxoid (dPly) and pneumococcal histidine triad protein D (PhtD), combined with 10 polysaccharide conjugates from the pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) in two investigational pneumococcal vaccine (PHiD-CV/dPl...

journal_title：Vaccine

authors： Odutola A,Ota MOC,Antonio M,Ogundare EO,Saidu Y,Owiafe PK,Worwui A,Idoko OT,Owolabi O,Kampmann B,Greenwood BM,Alderson M,Traskine M,Swinnen K,Verlant V,Dobbelaere K,Borys D

更新日期：2019-05-01 00:00:00

abstract：:Plasmid DNA vaccines encoding full-length antigen often induce both potent antibody and cytotoxic T lymphocyte (CTL) responses. Here, we examine strategies to exclusively elicit epitope-specific CTL responses using DNA constructs expressing a minimal class I MHC-restricted epitope of the nucleoprotein (NP) of influenz...

journal_title：Vaccine

authors： Iwasaki A,Dela Cruz CS,Young AR,Barber BH

更新日期：1999-04-09 00:00:00

abstract：:This phase 1 clinical trial assessed the safety and immunogenicity of a native outer membrane vesicle (NOMV) vaccine prepared from a lpxL2(-) synX(-) mutant of strain 44/76 with opcA expression stabilized. Thirty-four volunteers were assigned to one of the three dose groups (25 mcg, 25 mcg with aluminum hydroxide adju...

journal_title：Vaccine

authors： Keiser PB,Gibbs BT,Coster TS,Moran EE,Stoddard MB,Labrie JE 3rd,Schmiel DH,Pinto V,Chen P,Zollinger WD

更新日期：2010-10-08 00:00:00

abstract：:In this study, the haemolytic activities of Bupleurum chinense saponins (BCS) and its adjuvant potentials on the immune responses of ICR mice against ovalbumin (OVA) were evaluated. BCS showed a slight haemolytic effect, with its haemolytic percents being 3.32% and 1.19% at the concentrations of 500 and 250 microg/ml,...

journal_title：Vaccine

authors： Sun HX

更新日期：2006-02-27 00:00:00

abstract：:The ELISA method was used to titrate the humoral immune response in vaccinated mice. When mice were given two doses of a heat-killed salmonella vaccine 6 days apart, there was a steady but low-level increase of antibody synthesis. In contrast, if a booster vaccination was administered 21 days after the primary inocula...

journal_title：Vaccine

authors： Xu HR,Hsu HS,Moncure CW,King RA

更新日期：1993-01-01 00:00:00

abstract：:It is generally recognized that DNA vaccines are often less effective in large animals than in mice. One possible reason for this reduced effectiveness may be transfection efficiency and the low level of expression elicited by plasmid vectors in large animals. A possible way to improve plasmid gene expression in vivo ...

journal_title：Vaccine

authors： Babiuk S,Baca-Estrada ME,Foldvari M,Storms M,Rabussay D,Widera G,Babiuk LA

更新日期：2002-09-10 00:00:00

abstract：:Technological advancements, including landmark innovations in vaccinology through molecular virology, and significant transformation and changes in the society have taken place since the eradication of smallpox thirty years ago. The success with eradicating smallpox gave confidence for initiating the eradication of ot...

journal_title：Vaccine

authors： Tomori O

更新日期：2011-12-30 00:00:00

abstract：:Measles vaccination was performed in the arctic district of Scoresbysund, Greenland in 1968, which had never been exposed to natural measles. More than 90% of the total population was vaccinated and a 94-100% seroconversion was obtained. During a serological survey to examine the immunity status of the vaccinees, it w...

journal_title：Vaccine

authors： Pedersen IR,Mordhorst CH,Glikmann G,von Magnus H

更新日期：1989-08-01 00:00:00

abstract：:Human metapneumovirus (HMPV) is a major cause of morbidity and mortality from acute lower respiratory tract illness, with most individuals seropositive by age five. Despite the presence of neutralizing antibodies, secondary infections are common and can be severe in young, elderly, and immunocompromised persons. Precl...

journal_title：Vaccine

authors： Hastings AK,Gilchuk P,Joyce S,Williams JV

更新日期：2016-05-23 00:00:00

abstract：:We examined mothers' willingness to get their adolescent sons HPV vaccine. In December 2009, 2 months after approval of HPV vaccine for males, we surveyed a national sample of mothers with sons aged 9-18 (n=406). More mothers were definitely or probably willing to get their sons HPV vaccine if the vaccine were free (4...

journal_title：Vaccine

authors： Reiter PL,McRee AL,Gottlieb SL,Brewer NT

更新日期：2010-08-31 00:00:00

abstract：:The murine cytomegalovirus (MCMV) glycoprotein B (gB) gene was expressed in an adenovirus replication-deficient vector. This virus, designated Ad-gB, was used to immunize BALB/c and B6 mice by the intranasal (i.n.) route to induce an immune response. Following primary immunization, antibody was detected in serum of 10...

journal_title：Vaccine

authors： Shanley JD,Wu CA

更新日期：2003-06-02 00:00:00

abstract：:Development of meningococcal serogroups A, C, W-135 and Y conjugate vaccines could expand coverage against devastating meningococcal diseases. The immunogenicity of one dose of each one of five MenACWY-TT formulations versus a licensed ACWY polysaccharide vaccine was evaluated in 175 healthy subjects of 15-25 years. S...

journal_title：Vaccine

authors： Ostergaard L,Lebacq E,Poolman J,Maechler G,Boutriau D

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Zostavax™ is a live, attenuated varicella-zoster virus vaccine indicated for the prevention of herpes zoster (shingles). An observational post-licensure (Phase IV) study was conducted at Kaiser Permanente Northern California (KPNC), a US managed care organization, to assess the safety of zoster vaccine in pe...

journal_title：Vaccine

authors： Baxter R,Tran TN,Hansen J,Emery M,Fireman B,Bartlett J,Lewis N,Saddier P

更新日期：2012-10-19 00:00:00

abstract：:We assessed the tetanus immunity of the general Dutch population and of religious groups refusing vaccination by means of population-based study to evaluate the effect of tetanus vaccination. More than 95% of those born after the introduction of routine vaccination had tetanus antitoxin levels above the minimum protec...

journal_title：Vaccine

authors： de Melker HE,van den Hof S,Berbers GA,Nagelkerke NJ,Rümke HC,Conyn-van Spaendonck MA

更新日期：1999-08-20 00:00:00

abstract：:National Organized Cervical Cancer Screening (NOCCS) programs are lacking in most of the "Extended Middle East and North Africa" (EMENA) countries. Consequently, most cervical cancers are diagnosed late and are associated with high mortality. In fact, in most of these countries, national mortality data are unknown due...

journal_title：Vaccine

authors： Sancho-Garnier H,Khazraji YC,Cherif MH,Mahnane A,Hsairi M,El Shalakamy A,Osgul N,Tuncer M,Jumaan AO,Seoud M

更新日期：2013-12-30 00:00:00

abstract：:In many industrialized countries, hepatitis A incidence rates have declined steadily in the past decades. Since future cohorts of non-vaccinated elderly will lack protection against disease and the burden of hepatitis A is higher with increasing age, this could be an argument in favour of taking preventive measures su...

journal_title：Vaccine

authors： Suijkerbuijk AW,Lugnér AK,van Pelt W,Wallinga J,Verhoef LP,de Melker HE,de Wit GA

更新日期：2012-07-27 00:00:00

abstract：:Recombinant hepatitis B vaccine has been used widely in the world since 1991. The side effects of hepatitis B vaccine are seen rarely. In this paper, we present clinical and laboratory progress of an infant who gets severe thrombocytopenia after the second dosage hepatitis B vaccine. Our case is different from other c...

journal_title：Vaccine

authors： Polat A,Akca H,Dagdeviren E

更新日期：2008-12-02 00:00:00

abstract：:Japanese encephalitis (JE) vaccine has been used in childhood immunization programmes in Asia for many years. Also travellers from other parts of the world have been vaccinated before travelling in Asian countries. Recommendations for the use of JE vaccine are still debated because severe cases of adverse reactions ha...

journal_title：Vaccine

authors： Plesner AM,Rønne T

更新日期：1997-08-01 00:00:00

abstract：:Preventive immunization against HIV-1 infection requires a rapid immune response that does not rely exclusively on B or T cell memory. Innate immunity may fulfill this function as it may be activated directly at the time of HIV-1 transmission, inhibit early HIV-1 replication, stimulate adaptive immunity and enable spe...

journal_title：Vaccine

authors： Lehner T,Wang Y,Pido-Lopez J,Whittall T,Bergmeier LA,Babaahmady K

更新日期：2008-06-06 00:00:00

abstract：:The costs of developing and producing new-generation vaccines have increased compared to many of the older, "traditional" vaccines because of new technologies and regulatory requirements. While the public sector often supports basic research costs, private manufacturers are usually responsible for the investments in p...

journal_title：Vaccine

authors： Batson A,Meheus F,Brooke S

更新日期：2006-08-31 00:00:00

abstract：:A Phase I interventional Clinical Trial was performed with a potential tuberculosis vaccine, based on detoxified cellular fragments of M. tuberculosis, named RUTI. The objective was to evaluate the safety profile and T-cell immune responses over a 6-month period following subcutaneous inoculation. The double-blind, ra...

journal_title：Vaccine

authors： Vilaplana C,Montané E,Pinto S,Barriocanal AM,Domenech G,Torres F,Cardona PJ,Costa J

更新日期：2010-01-22 00:00:00

abstract：:The case-control methodology is frequently used to evaluate vaccine effectiveness post-licensure. The results of such studies provide important insight into the level of protection afforded by vaccines in a 'real world' context, and are commonly used to guide vaccine policy decisions. However, the potential for bias a...

journal_title：Vaccine

authors： Verani JR,Baqui AH,Broome CV,Cherian T,Cohen C,Farrar JL,Feikin DR,Groome MJ,Hajjeh RA,Johnson HL,Madhi SA,Mulholland K,O'Brien KL,Parashar UD,Patel MM,Rodrigues LC,Santosham M,Scott JA,Smith PG,Sommerfelt H,Tate

更新日期：2017-06-05 00:00:00

abstract：:The Lister (Elstree) strain of vaccinia virus, used in Israel for vaccination against smallpox, was studied in tissue cultures and in a mouse model. The virus failed to reach the brain of the mice when inoculated intranasally at a dose of 500,000 plaque forming units, but was lethal for 50% of them, when injected intr...

journal_title：Vaccine

authors： Abdalrhman I,Gurt I,Katz E

更新日期：2006-05-08 00:00:00

abstract：:The purpose of the present research work is to explore the potential of dendrosomes in genetic immunization against hepatitis B. Plasmid DNA encoding pRc/CMV-HBs[S] (5.6 kb), encoding the small region of the hepatitis B surface antigen, was complexed with 5th generation poly(propyleneimine) dendrimer (PPI) in differen...

journal_title：Vaccine

authors： Dutta T,Garg M,Jain NK

更新日期：2008-06-25 00:00:00

abstract：:One hundred and fourteen children, born to HBsAg-positive mothers received in the first year of life passive active prophylaxis for hepatitis B virus (HBV). They have been followed up to 10 years. A booster dose given in a cohort at the 5th year does not seem to increase protection against HBV. No difference in immuno...

journal_title：Vaccine

authors： Resti M,Azzari C,Mannelli F,Rossi ME,Lionetti P,Vierucci A

更新日期：1997-08-01 00:00:00

abstract：:Meat contamination by Salmonella spp. is emerging as a major cause of human enteric infections in industrialized countries. The attempts to reduce human cases of salmonellosis encompass pre- and post-harvest interventions. In this context, vaccination of pigs may represent an effective instrument in eliminating/reduci...

journal_title：Vaccine

authors： Pesciaroli M,Gradassi M,Martinelli N,Ruggeri J,Pistoia C,Raffatellu M,Magistrali CF,Battistoni A,Pasquali P,Alborali GL

更新日期：2013-06-12 00:00:00