Abstract:
OBJECTIVE:Methylxanthines are among the most commonly prescribed drugs in neonatal intensive care. This study evaluates the effect of caffeine on oxygen consumption and metabolic rate in premature infants with idiopathic apnea. METHODS:Eighteen preterm infants at gestational ages from 28 to 33 weeks and birth weights of 890 to 1680 g were enrolled in the study. Nine preterm infants received caffeine therapy, and 9 served as a control group. Oxygen consumption and energy expenditure were examined before, during, and after caffeine treatment. RESULTS:Oxygen consumption increased significantly from 7.0 +/- 0.9 before caffeine to 8.8 +/- 0.7 mL/kg/min after 48 hours of caffeine therapy, and energy expenditure increased from 2.1 +/- 0.3 to 3.0 +/- 0.2 kcal/kg/hour. During the observation period of 4 weeks of caffeine treatment, oxygen consumption increased significantly in the caffeine group compared with the control patients. In the caffeine group, a lower environmental temperature was sufficient to maintain a normal body temperature. With similar caloric intake in both groups during the study period, daily weight gain in the control group was significantly higher (21 +/- 4 vs 42 +/- 2 g/d). None of the other parameters recorded changed during caffeine therapy. CONCLUSION:Long-term administration of caffeine in preterm infants is associated with an increase in oxygen consumption and with a reduction of weight gain. This may have implications for clinical practice as nutritional regimens need to be adjusted during this therapy.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Bauer J,Maier K,Linderkamp O,Hentschel Rdoi
10.1542/peds.107.4.660subject
Has Abstractpub_date
2001-04-01 00:00:00pages
660-3issue
4eissn
0031-4005issn
1098-4275journal_volume
107pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:BACKGROUND AND OBJECTIVES:Pediatric surveillance of young children depends on providers' assessment of developmental milestones, yet normative data are sparse. Our objectives were to develop new norms for common milestones to aid in clinical interpretation of milestone attainment. METHODS:We analyzed responses to the ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-0374
更新日期:2019-12-01 00:00:00
abstract::Midgut volvulus due to malrotation may result in loss of the small bowel. Until now, after derotation of the volvulus, pediatric surgeons do not deal with the mesenteric thrombosis, which causes continuing ischemia of the intestine. On occasion, a "second look" laparotomy is performed in the hope that some improvement...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-2115
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Infants awaiting heart transplantation for congenital heart disease frequently require prostaglandin E1 (PGE1) infusion for prolonged periods. As a result, complications of prolonged PGE1 infusion, such as cortical hyperostosis, are being encountered more commonly. OBJECTIVE:To determine the incidence and s...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to identify the healing process and outcome of hymenal injuries in prepubertal and adolescent girls. METHODS:This multicenter, retrospective project used photographs to document the healing process and outcome of hymenal trauma that was sustained by 239 prepubertal and puberta...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2006-0964
更新日期:2007-05-01 00:00:00
abstract::To determine the rate of childhood under-vaccination, rate and types of missed opportunities (MOs) for vaccinations, and the contribution of MOs to the undervaccination of preschool-age children, the authors conducted a retrospective medical chart review in seven primary care settings in the Rochester, NY, area: a hos...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:Our objective was to determine the impact of Newborn Individualized Developmental Care and Assessment Program (NIDCAP)-based care on length of stay of very low birth weight (VLBW) infants. Secondary outcome measures were days of ventilation, incidence of chronic lung disease, and 18-month neurodevelopmental o...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2008-3808
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:Osteonecrosis of the hip has been reported in human immunodeficiency virus (HIV)-infected adults; whether this is related to HIV infection or its treatment is unknown. There has been 1 report of osteonecrosis among HIV-infected children. Specifically, avascular necrosis of the hip consistent with Legg-Calvé-P...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.109.5.e74
更新日期:2002-05-01 00:00:00
abstract::The Accreditation Council for Graduate Medical Education (ACGME) established guidelines in 1989 requiring pediatric residents to attend a continuity clinic (CC) one half-day per week. OBJECTIVE. To assess pediatric residents' CCs, with an emphasis on those factors potentially affecting house staff education and patien...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract:OBJECTIVE:Although prior population-based studies have found that children in foster care use more mental health services than their Medicaid peers, less is known about how different experiences in foster care impact the likelihood of mental health service use. The primary aim of this study is to test the hypothesis th...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.113.5.1336
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:We aimed to describe the clinical features and outcome of human parechovirus (HPeV) encephalitis cases identified by the Australian Childhood Encephalitis (ACE) study. METHODS:Infants with suspected encephalitis were prospectively identified in 5 hospitals through the (ACE) study. Cases of confirmed HPeV inf...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2015-2848
更新日期:2016-02-01 00:00:00
abstract::To improve child health at a community level, pediatricians require knowledge and skills that have not been traditionally included in residency training. Recent policy statements from the American Academy of Pediatrics and requirements from Accreditation Council for Graduate Medical Education Residency Review committe...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-2825J
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of high titer respiratory syncytial virus (RSV) immune globulin (RSVIG) in the treatment of previously healthy children hospitalized with proven RSV lower tract infection (LRI). METHOD:Infants and young children =2 years of age with RSV LRI of =4 days duration, and respiratory sc...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1542/peds.100.6.937
更新日期:1997-12-01 00:00:00
abstract::Commercially available mouse monoclonal antibodies to human IgG subclass (IgG1 to IgG4) were applied to an enzyme-linked immunosorbent assay to measure IgG subclass-specific antibodies to varicella-zoster virus in children naturally infected with varicella-zoster virus and in varicella vaccine recipients. In children ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1987-12-01 00:00:00
abstract:BACKGROUND:Studies suggest that giving newly born preterm infants sustained lung inflation (SLI) may decrease their need for mechanical ventilation (MV) and improve their respiratory outcomes. METHODS:We randomly assigned infants born at 25 weeks 0 days to 28 weeks 6 days of gestation to receive SLI (25 cm H2O for 15 ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2014-1692
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To verify and determine the cause of an increase in the referral of infants with plagiocephaly without synostosis (PWS) to a single tertiary craniofacial center. DESIGN:A chart review was performed for 269 infants with a diagnosis of PWS who presented to a single tertiary craniofacial center between 1979 and...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Approximately 1 in 5 child passenger deaths in the United States involves an alcohol-impaired driver, most commonly the child's own driver. The objective of this study was to document recent trends and state-specific rates of these deaths. METHODS:A descriptive analysis of 2001-2010 Fatality A...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-2318
更新日期:2014-06-01 00:00:00
abstract:UNLABELLED:Because late repair of coarctation of the aorta (COA) is associated with premature cardiovascular disease in adult life, early detection and treatment is important. OBJECTIVES:To determine the timing of referral to see whether early detection of COA has improved in the past decade, to evaluate the pattern o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVE:Smoking among people who have asthma may be a serious health problem. We studied the prevalence of smoking and the relations between smoking and asthma, symptoms, medicine, and gender differences among adolescents with asthma. METHODS:A national cross-sectional study on health and lifestyles was performed in...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.111.5.e562
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To examine the association between child maltreatment (abuse and neglect) and long-term cognitive outcomes within a prospective birth cohort. METHODS:A birth cohort of 7223 children was recruited. Independent reports of suspected child maltreatment were confidentially linked to the longitudinal study databas...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-3479
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Treatment of otitis media is the most frequent reason for administering antibiotics to children in the United States. However, only limited data are available on medical effectiveness of antibiotic prescribing patterns for otitis media and their associated expenditures or the factors that influence antibioti...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.100.4.585
更新日期:1997-10-01 00:00:00
abstract::There is considerable literature dealing with the responsibilities of clinical department chairmen, which primarily emphasizes the importance of developing a sound and facilitating administration. This is dependent on the hiring of appropriate support personnel, developing a representative committee structure, being a...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVES:To assess the relation between exposure to maternal depression before age 5 and 5 domains of developmental vulnerability at school entry, overall, and by age at exposure. METHODS:This cohort study included all children born in Manitoba, Canada, who completed the Early Development Instrument between 2005 and...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2020-0794
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Hepatitis C virus (HCV) prevalence doubled among pregnant women from 2009 to 2014, reaching 3.4 per 1000 births nationwide. Infants exposed to HCV may acquire HCV by vertical transmission. National guidelines recommend that infants exposed to HCV be tested; however, it is unclear if these recommendations are...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-2482
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:Child abuse (CA) can present with a spectrum of signs and symptoms. Apparent life-threatening events (ALTEs) may be a subtle presentation of CA. Retinal hemorrhages (RHs) are a well-described finding in some patients with CA. We hypothesized that screening children who present with a chief complaint of an ALT...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.110.3.557
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Trichomoniasis is a prevalent cause of vaginitis among adolescents that increases the risk of acquiring other sexually transmitted diseases and of negative pregnancy outcomes. Treatment of trichomoniasis is therefore essential for improving sexual and reproductive health outcomes. A timely, se...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-2072
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Previous studies have suggested changes in self-concept with successful treatment of primary nocturnal enuresis (PNE), but behavioral changes have not been reported as a consistent associated finding. OBJECTIVE:To determine if self-concept and behavior change after 6 months of treatment of monosymptomatic P...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:This report assessed the proportion of US 10th graders (average age, 16) who saw a physician in the past year and were asked and given advice about their drinking. We hypothesized that advice would vary by whether students were asked about drinking and their drinking, bingeing, and drunkenness frequency. ME...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-1496
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVES:Inadequate sleep during infancy is associated with adverse outcomes for infants and families. We sought to improve sleep behaviors and duration through a responsive parenting (RP) intervention designed for obesity prevention. METHODS:The Intervention Nurses Start Infants Growing on Healthy Trajectories (INS...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2016-0762
更新日期:2016-07-01 00:00:00
abstract::Epigenetics, the study of functionally relevant chemical modifications to DNA that do not involve a change in the DNA nucleotide sequence, is at the interface between research and clinical medicine. Research on epigenetic marks, which regulate gene expression independently of the underlying genetic code, has dramatica...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2013-1032F
更新日期:2013-12-01 00:00:00
abstract::The Affordable Care Act (ACA) introduces enormous policy changes to the health care system with several anticipated benefits and a growing number of unanticipated challenges for child and adolescent health. Because the ACA gives each state and their payers substantial autonomy and discretion on implementation, underst...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2014-0881
更新日期:2014-10-01 00:00:00