Abstract:
BACKGROUND:Previous studies have suggested changes in self-concept with successful treatment of primary nocturnal enuresis (PNE), but behavioral changes have not been reported as a consistent associated finding. OBJECTIVE:To determine if self-concept and behavior change after 6 months of treatment of monosymptomatic PNE by conditioning alarm or desmopressin acetate (DDAVP). DESIGN:Randomized, controlled trial in an inner-city hospital clinic. Subjects were 182 children referred or recruited through media publicity, randomly assigned both to 1 of 8 pediatricians and 1 of 3 treatment groups (alarm, DDAVP, or placebo). Included were children >7 years old with PNE, no daytime symptoms, bladder capacity >50% expected, and wetting >3 times a week. Excluded were children with central nervous system disorders or developmental delays, and those currently on DDAVP or alarm. Subjects completed the Piers-Harris Children's Self-Concept Scale and Harter's Perceived Competence Scale for Children (PCSC) at initial visit and after 6 months of treatment. Parents completed the Achenbach Child Behavior Checklist (CBCL) at the same times. RESULTS:After 6 months of treatment the Piers-Harris total score showed a highly significant treatment by period interaction effect for DDAVP, a significant effect for alarm, and no effect for placebo. For children who achieved 75% dryness the CBCL showed a treatment by improvement interaction effect that was highly significant for DDAVP and placebo with no effect for alarm. For the PCSC there were no treatment or outcome interaction effects. After 6 months of treatment there were significant changes over time unrelated to outcome or treatment in the Piers-Harris Subscales and in the CBCL Internalizing and Externalizing Scores, and the Social Thought and Attention Problems Subscales. The PCSC was more stable with no changes in total score, and positive changes over time in only 2 Subscales, Scholastic and Social. CONCLUSION:Children's self-concept improved with the type of treatment and amount of success. Parents' perceptions of behavior improve with type of treatment and amount of success. Children rate their self-concept and some physical attributes better after treatment with any of DDAVP, alarm, or placebo regardless of outcome. Frequent follow-up with emotional support and encouragement appear to be important components of an efficacious intervention for children with nocturnal enuresis.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Longstaffe S,Moffatt ME,Whalen JCsubject
Has Abstractpub_date
2000-04-01 00:00:00pages
935-40issue
4 Pt 2eissn
0031-4005issn
1098-4275journal_volume
105pub_type
临床试验,杂志文章,随机对照试验相关文献
PEDIATRICS文献大全abstract:OBJECTIVE:Patient registries can effectively collect data over a long period of time to provide a better understanding of the typical presentation of specific conditions. The autism spectrum disorders (ASDs) have experienced a marked increase in reported prevalence over the past 20 years for reasons that are not comple...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-2851E
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:Adolescents with justice system involvement have high rates of physical and behavioral health disorders and are potentially high users of costly health care services. We examined emergency department (ED) and hospital use among a national sample of adolescents with various levels of justice involvement. MET...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-1144
更新日期:2017-11-01 00:00:00
abstract::An adolescent female patient presenting with subacute onset of dysphagia and hoarseness underwent a direct laryngoscopy, which revealed epiglottitis. After 2 hospitalizations and multiple consultations and biopsies, all infectious testing results for viral, bacterial, fungal, and acid-fast bacilli etiologies were nega...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-2399
更新日期:2020-03-01 00:00:00
abstract::Circadian rhythms are endogenously generated rhythms with a period length of approximately 24 hours. Evidence gathered during the past decade indicates that the circadian timing system develops prenatally and the suprachiasmatic nuclei, the site of a circadian clock, is present by midgestation in primates. Recent evid...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.112.2.373
更新日期:2003-08-01 00:00:00
abstract:CONTEXT:Birth asphyxia contributes substantially to neonatal mortality in low- and middle-income countries (LMICs). The effects of training birth attendants in neonatal resuscitation (NR) on mortality are limited by falloff of skills and knowledge over time and transference of learned skills into clinical practice. OB...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2015-4490
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Macroorchidism is one of the most well-described clinical characteristics of men with fragile X syndrome, but little information has been available regarding macroorchidism in prepubertal boys with fragile X. The purpose of this study was to learn whether macroorchidism is a characteristic of fragile X syndro...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract::Clostridium difficile was isolated from the feces of two infants who had developed watery diarrhea with blood-tinged stain. One child suffered from diarrhea after five days of parenteral oxacillin therapy; the diarrhea subsided within three days of cessation of therapy. The other infant developed diarrhea following fo...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract:OBJECTIVE:To determine the short-term efficacy of meso-2,3-dimercaptosuccinic acid (DMSA) in mild to moderately lead poisoned children. METHODS:Medical records of all pediatric patients receiving 19 days of DMSA between June 1991 and May 1993 were reviewed retrospectively. Patients were included if their pretreatment ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract:OBJECTIVE:To determine the sound environment of preterm infants cared for in the NICU and to test the hypothesis that infants exposed to more adult language will make more vocalizations. METHODS:This was a prospective cohort study of 36 infants who had a birth weight of ≤1250 g. Sixteen-hour recordings of the infant s...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-0609
更新日期:2011-11-01 00:00:00
abstract::Aerosolized racemic epinephrine, but not L-epinephrine, is commonly used in treating croup. The efficacy and adverse effects of nebulized racemic and L-epinephrine in the treatment of laryngotracheitis were compared. Children 6 months to 6 years of age with a croup score of 6 or above were assigned in a randomized dou...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of home intervention with drug-abusing women on parenting behavior and attitudes, and on children's development. DESIGN:A randomized, clinical trial of 60 drug-abusing women recruited prenatally and randomized into an intervention (n = 31) or comparison (n = 29) group. There were no ...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-10-01 00:00:00
abstract:OBJECTIVE:Neonatal bacterial infections carry a high mortality when diagnosed late. Early diagnosis is difficult because initial clinical signs are nonspecific. Consequently, physicians frequently prescribe antibiotic treatment to newborn infants for fear of missing a life-threatening infection. This study was designed...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.114.1.1
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Survival of extremely preterm (EP; <28 weeks' gestation) infants has increased over the last 2 decades. Equivalent reductions in developmental morbidity in early childhood have not been consistently reported. The aim of this study was to determine trends in neurodevelopmental outcomes at 8 year...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-4086
更新日期:2017-06-01 00:00:00
abstract::Two instances of metopic craniosynostosis provide dramatic experiments of nature which implicate fetal head constraint as one cause of early sutural fusion. The presumed restriction of growth stretch at the metopic suture in one instance was due to a bicornuate uterus in which the fetal head was markedly constrained. ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVE:We assessed the effects of very preterm birth (gestational age <32 weeks or birth weight <1501 g) and prematurity-related morbidities on health care costs during the fifth year of life. METHODS:The study population consisted of 588 very preterm children and 176 term control subjects born in 2001-2002. Costs ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-2882
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the reliability and validity of a previously derived clinical dehydration scale (CDS) in a cohort of children with gastroenteritis and evidence of dehydration. METHODS:Participants were 226 children older than 3 months who presented to a tertiary care emergency department and required intravenou...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-2985
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To determine if serum levels of S100B are higher in children with CHT and ICI as detected by cranial CT and if long bone fractures affect the level of S100B in children with CHT and skeletal injury. METHODS:Children <18 years of age who presented to an urban pediatric emergency department or were transferred...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-1493
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVES:Our goal was to evaluate the possible correspondence between antitissue transglutaminase of immunoglobulin A class levels and stage of mucosal damage in patients affected by celiac disease. In addition, we assessed clinical use of antitissue transglutaminase values to predict biopsy results. METHODS:One tho...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-0604
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:End-of-life clinical care in cystic fibrosis (CF) differs substantially from terminal care in childhood cancer. To examine this difference, we reviewed the medical care of a cohort of CF patients treated at Children's Hospital, Boston, to document the use of preventive, therapeutic, and palliative care in the...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.100.2.205
更新日期:1997-08-01 00:00:00
abstract::Despite the absence of a clear-cut rationale for their use, corticosteroids are widely employed in the treatment of dengue shock syndrome. Previous comparative therapeutic trials have yielded contradictory results. Resolution of this therapeutic controversy has been attempted with a double-blind evaluation of the clin...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:In 2000, the American Diabetes Association issued recommendations for type 2 diabetes mellitus screening among children. They recommended testing children > or =10 years of age who have a body mass index (BMI) of >85th percentile for age and at least 2 other risk factors (family history of type 2 diabetes, h...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.114.1.141
更新日期:2004-07-01 00:00:00
abstract::A pilot study investigated the neurologic, cognitive, and behavioral consequences of nonfatal infancy apnea. Fifteen formerly apneic, monitored children were compared with age-similar siblings and with age-sex matched playmates. Significant impairment in gross motor development and mild cognitive deficiencies were obs...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1984-05-01 00:00:00
abstract:BACKGROUND:Early shared reading and literacy promotion benefits have stimulated international interest in the development of early-years literacy-promotion programs despite limited evidence of effectiveness at a broader population level. OBJECTIVE:To determine whether a population-based primary care literacy promotion...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2009-3043
更新日期:2011-03-01 00:00:00
abstract::Approximately 25% of the world's children aged <5 years have stunted growth, which is associated with increased mortality, cognitive dysfunction, and loss of productivity. Reducing by 40% the number of stunted children is a global target for 2030. The pathogenesis of stunting is poorly understood. Prenatal and postnat...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2016-0641
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:To examine the effects of dietary experience and milk feeding regimen on acceptance of their first vegetable by 4- to 6-month-old infants. DESIGN:Longitudinal study, of 26-days duration, observing infants aged 4 to 6 months at the start of the study. Random assignment to treatments, within-subject control. ...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-02-01 00:00:00
abstract::Temperament is the tendency to express particular emotions with a certain intensity that is unique to each individual child. Although temperament seems to be biologically based, learning to regulate emotional expressions depends on caregiver input and socialization. Part of this process involves forming a trusting rel...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVES:Multisystem inflammatory syndrome in children (MIS-C) has spread through the pediatric population during the coronavirus disease 2019 pandemic. Our objective for the study was to report the prevalence of conduction anomalies in MIS-C and identify predictive factors for the conduction abnormalities. METHODS:...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2020-009738
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:We performed a randomized, double-masked, parallel-groups, placebo-controlled trial of recombinant granulocyte colony-stimulating factor (rG-CSF) administration to 44 preterm neonates who had blood cultures obtained and antibiotics begun because of the clinical diagnosis of early-onset sepsis. Two primary out...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1542/peds.107.1.30
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:Studies of US adolescents have linked exposure to movie smoking with smoking behavior. It is unclear whether European adolescents are also responsive to movie tobacco imagery. METHODS:A longitudinal study was conducted to assess exposure to movie smoking in 2711 German never-smokers (aged 10 to 16 years). Mo...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-1201
更新日期:2008-01-01 00:00:00
abstract::Central nervous system manifestations in association with adenovirus infections have rarely been documented. In this report, four children, ages 4, 5, 6, and 10 years, with adenoviral meningoencephalitis are described. Adenoviruses were recovered from CSF specimens in all four patients. ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1978-02-01 00:00:00