Clot dissolution: a novel treatment of midgut volvulus.

Abstract:

:Midgut volvulus due to malrotation may result in loss of the small bowel. Until now, after derotation of the volvulus, pediatric surgeons do not deal with the mesenteric thrombosis, which causes continuing ischemia of the intestine. On occasion, a "second look" laparotomy is performed in the hope that some improvement in blood supply to the intestine has occurred. We describe a new combined treatment to restore intestinal perfusion based on digital massage of the superior mesenteric vessels after derotation and systemic infusion of tissue-type plasminogen activator. This new therapy has been successful in 2 neonates with severe intestinal ischemia due to volvulus.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Kiely EM,Pierro A,Pierce C,Cross K,De Coppi P

doi

10.1542/peds.2011-2115

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

e1601-4

issue

6

eissn

0031-4005

issn

1098-4275

pii

peds.2011-2115

journal_volume

129

pub_type

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