Low-dose Adriamycin remission maintenance therapy for pediatric solid tumors.

abstract：BACKGROUND:Cytochrome P450 1A1 (CYP1A1) is involved in the 2-hydroxylation of estrogen, the hormone that plays a critical role in the etiology of breast carcinoma. METHODS:The authors evaluated common polymorphisms in the CYP1A1 gene in relation to breast carcinoma risk in a large population-based case-control study a...

journal_title：Cancer

authors： Boyapati SM,Shu XO,Gao YT,Cai Q,Jin F,Zheng W

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Ordinary craniopharyngiomas affecting sellar regions of children and preadolescents are composed of ameloblastomatous and/or squamous constituents. The authors encountered an autopsy case of a stillborn infant with a large craniopharyngioma with unusual manifestations. METHODS:The craniopharyngioma was anal...

journal_title：Cancer

authors： Yamada H,Haratake J,Narasaki T,Oda T

更新日期：1995-06-15 00:00:00

abstract：BACKGROUND:A review of the literature indicated variable underestimation rates for breast core-needle biopsy (CNB) based on generally small series. In this article, the authors present precise estimates for overall underestimation and for categories of histologic underestimates (including categories that reflect contem...

journal_title：Cancer

authors： Houssami N,Ciatto S,Ellis I,Ambrogetti D

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to analyze the extent of hypoxia in prostate carcinoma tumors using the Eppendorf pO(2) microelectrode and correlate this with pretreatment characteristics and prognostic factors. METHODS:Custom-made Eppendorf pO(2) microelectrodes were used to obtain pO(2) measurements from th...

journal_title：Cancer

authors： Movsas B,Chapman JD,Greenberg RE,Hanlon AL,Horwitz EM,Pinover WH,Stobbe C,Hanks GE

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Even when they are analogous in microscopic and macroscopic appearance, tumors vary in their response rates to radiotherapy. Cell culture and xenograft experiments with colorectal cell lines have demonstrated that wild-type p53 increases radiosensitivity. Hence, the authors investigated, in a well-defined po...

journal_title：Cancer

authors： Nehls O,Klump B,Holzmann K,Lammering G,Borchard F,Gruenagel HH,Gaco V,Gregor M,Porschen R

更新日期：1999-06-15 00:00:00

abstract：BACKGROUND:The health-related functioning of patients with cancer is compromised by several factors, including the disease process, treatment, and the various symptoms that are produced by both disease and treatment. This study was designed to specify the relationship between patients' pain severity and their self-repo...

journal_title：Cancer

authors： Wang XS,Cleeland CS,Mendoza TR,Engstrom MC,Liu S,Xu G,Hao X,Wang Y,Ren XS

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:The necessity to develop more effective chemotherapy regimens in advanced nonsmall cell lung carcinoma (NSCLC) prompted the authors to evaluate the paclitaxel-ifosfamide-cisplatin (PIC) combination, developed on the basis of high individual single-agent activity, in vitro synergism, and tolerance as determin...

journal_title：Cancer

authors： Kosmas C,Tsavaris NB,Polyzos A,Kalofonos HP,Sepsas E,Malamos NA,Vadiaka M,Dosios T,Antonopoulos MJ

更新日期：2000-08-15 00:00:00

abstract：:A brother and sister with Fanconi's anemia, having typical skeletal deformity and characteristic chromosomal breaks in their lymphocytes and who followed the typical clinical course, with progressive bone marrow insufficiency beginning late in the first decade, are described. The natural history of the disease before ...

journal_title：Cancer

authors： Jacobs P,Karabus C

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:The current study evaluated whether the risk of developing thyroid cancer in Asian women was associated with infertility and the use of fertility drugs. METHODS:The authors conducted a large, retrospective cohort study using Taiwan's National Health Insurance Research Database. From the insurance claims dat...

journal_title：Cancer

authors： Ding DC,Chen W,Wang JH,Lin SZ,Sung FC

更新日期：2019-05-15 00:00:00

abstract：:Ninety-four patients with lymphoma involving the extradural space with spinal cord compression proven at the time of laminectomy were reviewed. There were about three times as many patients with non-Hodgkin's lymphoma than with Hodgkin's disease. The majority of those with Hodgkin's disease had a proven histologic dia...

journal_title：Cancer

authors： Haddad P,Thaell JF,Kiely JM,Harrison EG,Miller RH

更新日期：1976-10-01 00:00:00

abstract：:BALB/c mice were hyperimmunized with ACHN (ATCC CRL 1611, American Type Culture Collection, Rockville, Maryland), a stable in vitro cell line derived from a malignant pleural effusion in a 22-year-old man with renal cell carcinoma. The hyperimmune spleen cells were fused with NS-1 murine myeloma cells using polyethyle...

journal_title：Cancer

authors： Kochevar J

更新日期：1987-06-15 00:00:00

abstract：:The majority of patients with advanced ovarian cancer progress after first-line therapy and require further treatment. Tumor biology, prior chemotherapy, responses to previous therapy, performance status, and toxicity are the characteristics that influence treatment choice. These criteria have been linked to the time ...

journal_title：Cancer

authors： Pignata S,Pisano C,Di Napoli M,Cecere SC,Tambaro R,Attademo L

更新日期：2019-12-15 00:00:00

abstract：:Detailed cytogenetic studies were performed in 41 patients with cutaneous T-cell lymphoma (CTCL): four patients had limited plaques, 13 patients had generalized plaques, eight patients had cutaneous tumors, 16 patients had generalized erythroderma, and four additional patients, who had relatively benign chronic dermat...

journal_title：Cancer

authors： Whang-Peng J,Bunn PA Jr,Knutsen T,Matthews MJ,Schechter G,Minna JD

更新日期：1982-10-15 00:00:00

abstract：:Over a 7 year period, 85 cancer patients were managed by the nutrition service of St. Joseph's Hospital, Toronto. All these patients were nutritionally depleted, had obstruction to the gastrointestinal tract, or had postoperative complications such as enterocutaneous fistulas, evisceration or intraabdominal sepsis, wh...

journal_title：Cancer

authors： Deitel M,Vasic V,Alexander MA

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:Patients with renal masses are at risk for having or developing chronic kidney disease (CKD) stage 3 (glomerular filtration rate [GFR] <60 mL per minute/1.73 m2). In this study, the authors investigated whether the Screening for Occult Renal Disease (SCORED) model could identify patients with renal masses wh...

journal_title：Cancer

authors： Lucas SM,Nuss G,Stern J,Lotan Y,Sagalowsky AI,Cadeddu JA,Raj GV

更新日期：2008-11-15 00:00:00

abstract：:We assessed the frequency of silent (i.e., clinically asymptomatic) cirrhosis among 305 patients with hepatocellular carcinoma (HCC) and cirrhosis in relation to the patients' country of birth, the cause of the cirrhosis, clinical features, and hepatitis B surface antigen (HBsAg) status. Overall, 56% of the patients h...

journal_title：Cancer

authors： Zaman SN,Johnson PJ,Williams R

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:English and Chinese are two of the most widely used primary languages in the world. Patients in many cancer centers have a variety of ethnic backgrounds and primary languages. The comparability of version 4 of the English and Chinese versions of the Functional Assessment of Cancer Therapy-General (FACT-G) an...

journal_title：Cancer

authors： Cheung YB,Thumboo J,Goh C,Khoo KS,Che W,Wee J

更新日期：2004-12-15 00:00:00

abstract：BACKGROUND:Although there have been a few reports dealing with the sarcomatous changes of intrahepatic cholangiocarcinoma, its clinicopathologic features as well as immunohistochemical nature remain obscure. METHODS:Among 155 cases of intrahepatic cholangiocarcinoma, 7 cases of sarcomatous cholangiocarcinoma were chos...

journal_title：Cancer

authors： Nakajima T,Tajima Y,Sugano I,Nagao K,Kondo Y,Wada K

更新日期：1993-09-15 00:00:00

abstract：:In this review, I describe the polymerase chain reaction (PCR) and its application to cancer diagnostics. I present recent improvements to PCR methodology, and describe some state-of-the-art detection methods and approaches used to diagnose various cancer markers, including ras genes, BCR/abl translocations, and G-pro...

journal_title：Cancer

authors： Lyons J

更新日期：1992-03-15 00:00:00

abstract：:Pancreatic carcinomas have been induced in Wistar and W/LEW rats by administration of total azaserine doses of 150-520 mg/kg by injection or oral routes over periods of 5-52 weeks. The latent period for development of invasive carcinomas was 1-2 years, but focal abnormalities in acinar cells appear earlier. The incide...

journal_title：Cancer

authors： Longnecker DS,Roebuck BD,Yager JD Jr,Lilja HS,Siegmund B

更新日期：1981-03-15 00:00:00

abstract：:Chemotherapy of advanced stages of large bowel cancer has until recently made little progress since the introduction of 5-FU 16 years ago. While survival is improved for patients who respond, 5-FU alone has made little impact on life span of the overall population of patients. Mitomycin-C and the chloroethyl nitrosour...

journal_title：Cancer

authors： Schein PS,Kisner D,MacDonald JS

更新日期：1975-12-01 00:00:00

abstract：:Categories of objective response to chemotherapy for 460 advanced relapsing prostate cancer patients evaluated in the initial first four randomized clinical trials of the National Prostatic Cancer Project were compared by survival and other patient and disease characteristics. The response criteria for stable were sho...

journal_title：Cancer

authors： Slack NH,Mittelman A,Brady MF,Murphy GP

更新日期：1980-12-01 00:00:00

abstract：:With nearly 80% of childhood cancer patients achieving cure, there are more adult survivors living now than at any other time in history. Because they are at risk for developing complications of treatment years later, it is recommended that survivors undergo systematic, regular monitoring into young adulthood and beyo...

journal_title：Cancer

authors： Freyer DR,Kibrick-Lazear R

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:This study sought to investigate biological/clinicopathological characteristics of neuroblastoma, undifferentiated subtype (NBUD). METHODS:This study examined 157 NBUD cases filed at the Children's Oncology Group Neuroblastoma Pathology Reference Laboratory, and survival rates of the patients were analyzed ...

journal_title：Cancer

authors： Wang LL,Suganuma R,Ikegaki N,Tang X,Naranjo A,McGrady P,London WB,Hogarty MD,Gastier-Foster JM,Look AT,Park JR,Maris JM,Cohn SL,Seeger RC,Shimada H

更新日期：2013-10-15 00:00:00

abstract：BACKGROUND:It has been suggested that tissue factor (TF) plays an important role in tumor metastasis. Its expression in sarcoma cells was reported to up-regulate the vascular endothelial growth factor (VEGF) gene and thereby enhance tumor angiogenesis, which is essential to tumor metastasis. Although many malignant tum...

journal_title：Cancer

authors： Seto S,Onodera H,Kaido T,Yoshikawa A,Ishigami S,Arii S,Imamura M

更新日期：2000-01-15 00:00:00

abstract：:Of 209 Hodgkin's disease patients treated at least 6 months with a five-drug combination of induction chemotherapy and having a complete remission, four patients developed acute myelogenous leukemia (AML) as a second malignant neoplasm. The overall relative risk for development of AML is 185.0 (P less than 0.05) and t...

journal_title：Cancer

authors： Bartolucci AA,Liu C,Durant JR,Gams RA

更新日期：1983-12-15 00:00:00

abstract：BACKGROUND:Febrile neutropenia (FN) is a serious and potentially life-threatening condition that may develop in patients with cancer who receive myelosuppressive chemotherapy. The risk of mortality from FN is not well characterized in current clinical practice. METHODS:Patients with cancer who were receiving chemother...

journal_title：Cancer

authors： Lyman GH,Michels SL,Reynolds MW,Barron R,Tomic KS,Yu J

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:In a randomized Phase II study, the authors evaluated the activity and toxicity of the new cisplatin, doxorubicin, and mitomycin C (PAM) combination, that includes cisplatin (P) instead of 5-fluorouracil as in the 5-fluorouracil, doxorubicin, and mitomycin C (FAM) combination, in patients with advanced gastr...

journal_title：Cancer

authors： De Lisi V,Cocconi G,Angelini F,Cavicchi F,Di Costanzo F,Gilli G,Rodinò C,Soldani M,Tonato M,Finardi C

更新日期：1996-01-15 00:00:00

abstract：:On the basis of previous findings at this institution, VM-26 and Cytosine Arabinoside (ara-C) were used in combination to treat 33 children with refractory acute lymphocytic leukemia (ALL). Chemotherapy was given by vein twice a week for four weeks at dosage of 300 mg/m2 for ara-C and 50, 75, 110, 165, or 200 mg/m2 fo...

journal_title：Cancer

authors： Rivera G,Aur RJ,Dahl GV,Pratt CB,Wood A,Avery TL

更新日期：1980-03-15 00:00:00

abstract：:This report identifies five general conclusions that emerged from the Second Workshop on Methodology in Behavioral and Psychosocial Cancer Research. These conclusions address diverse topics, including a focus on areas other than methodology; an emphasis on the transfer of technology and knowledge to applied settings; ...

journal_title：Cancer

authors： Burish TG

更新日期：1991-02-01 00:00:00