Chromosomal imbalances identified by comparative genomic hybridization in sporadic parathyroid adenomas.

abstract：OBJECTIVE:In the absence of widely available measures of determining free and/or bioavailable testosterone (BioT) physicians may use formulae such as the free androgen index (FAI) to estimate free testosterone. We compared the efficacy of calculated markers of androgen status in predicting serum BioT and hypogonadism. ...

journal_title：European journal of endocrinology

authors： Morris PD,Malkin CJ,Channer KS,Jones TH

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:A stress reaction involving increased cortisol release, which has not been documented thus far, might affect the assessment of selectivity of catheterization during adrenal venous sampling (AVS). OBJECTIVE:To investigate whether an ACTH-driven cortisol release occurs during AVS and whether it influences the...

journal_title：European journal of endocrinology

authors： Seccia TM,Miotto D,Battistel M,Motta R,Barisa M,Maniero C,Pessina AC,Rossi GP

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Gastric carcinoid tumours type 1 (GCA1) originate from hyperplastic enterochromaffin-like (ECL) cells secondary to hypergastrinaemia. Treatment with somatostatin analogues (SSA) might impede ECL-cell hyperplasia by suppressing gastrin secretion and/or by a direct anti-proliferative effect on ECL cells. We co...

journal_title：European journal of endocrinology

authors： Grozinsky-Glasberg S,Kaltsas G,Gur C,Gal E,Thomas D,Fichman S,Alexandraki K,Barak D,Glaser B,Shimon I,Gross DJ

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:We examined the hypothesis that high FGF-23 levels early after transplantation contribute to the onset of hypophosphatemia, independently of parathyroid hormone (PTH) and other factors regulating phosphate metabolism. METHODS:We measured serum phosphate levels (sPi), renal tubular reabsorption of Pi (TmPi/G...

journal_title：European journal of endocrinology

authors： Trombetti A,Richert L,Hadaya K,Graf JD,Herrmann FR,Ferrari SL,Martin PY,Rizzoli R

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To examine the genes for AMP-activated protein kinase (AMPK) subunits alpha2 (PRKAA2) and gamma3 (PRKAG3) as candidates for polycystic ovary syndrome (PCOS) and its component traits. DESIGN AND METHODS:A total of 287 white PCOS women were recruited from the reproductive endocrinology clinic at the University...

journal_title：European journal of endocrinology

authors： Sproul K,Jones MR,Azziz R,Goodarzi MO

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To stop smoking is commonly associated with significant weight gain, but the mechanisms for this are poorly understood. We assessed the effects of smoking cessation on body weight, insulin sensitivity, β-cell function, and appetite. SUBJECTS AND METHODS:Twenty-seven long-term smokers (n=27; nine females/18 m...

journal_title：European journal of endocrinology

authors： Stadler M,Tomann L,Storka A,Wolzt M,Peric S,Bieglmayer C,Pacini G,Dickson SL,Brath H,Bech P,Prager R,Korbonits M

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:Validate the acromegaly quality of life (AcroQoL) questionnaire as a disease-generated questionnaire, which analyses physical and psychological domains, the latter subdivided into appearance and personal relationship sub-scales, to evaluate health-related quality of life (HRQoL) in acromegaly. DESIGN:Prospec...

journal_title：European journal of endocrinology

authors： Webb SM,Badia X,Surinach NL,Spanish AcroQol Study Group.

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:Evaluation of the efficiency of somatostatin analogues in the treatment of a mixed luteinizing hormone (LH)-, alpha-subunit-, prolactin (PRL)-secreting pituitary adenoma. DESIGN:A 30-year-old woman, with amenorrhaea-galactorrhaea, presented with a pituitary macroadenoma. The endocrine evaluation showed high ...

journal_title：European journal of endocrinology

authors： Saveanu A,Morange-Ramos I,Gunz G,Dufour H,Enjalbert A,Jaquet P

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND/AIM:Our previous studies showed that administration of dexamethasone plus food increased serum leptin levels 100% more than dexamethasone alone. We hypothesized that this increase in leptin from the meal could result directly from the provision of fuel metabolites rather than from the meal-induced rise in in...

journal_title：European journal of endocrinology

authors： Garcia-Lorda P,Nash W,Roche A,Pi-Sunyer FX,Laferrere B

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:An increased cardiovascular risk and mortality in hypopituitary patients receiving conventional hormonal treatment without GH replacement have been shown in several studies. Various atherogenic risk factors including endothelial dysfunction - an early event in the atherogenesis - are more expressed in adults...

journal_title：European journal of endocrinology

authors： Hána V,Prázný M,Marek J,Skrha J,Justová V

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Human appetite is stimulated by alcohol but the underlying mechanism is unknown. It is possible that hunger-stimulating hormones are mediators of this effect of alcohol. Ghrelin stimulates hunger, but how alcohol affects human ghrelin secretion has never been studied before. OBJECTIVE:To investigate whether...

journal_title：European journal of endocrinology

authors： Calissendorff J,Danielsson O,Brismar K,Röjdmark S

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of long-term GH in GH-deficient adults, as predicted by IGF-I levels. METHODS:Patients received GH, 5 microg/kg per day for 1 Month and 10 microg/kg per day for another 12-30 Months. Changes in body composition, cardiac structure/function, serum lipids and quality of life were meas...

journal_title：European journal of endocrinology

authors： Ezzat S,Fear S,Gaillard RC,Gayle C,Marcovitz S,Mattioni T,Nussey S,Rees A,Svanberg E

更新日期：2003-12-01 00:00:00

abstract：UNLABELLED:In healthy boys, the pituitary-gonadal axis exhibits diurnal variation in early puberty. Serum testosterone levels are higher during the night and low or immeasurable during the day. These fluctuating levels of circulating androgens in early pubertal boys are difficult to monitor. Prostate specific antigen (...

journal_title：European journal of endocrinology

authors： Juul A,Müller J,Skakkebaek NE

更新日期：1997-04-01 00:00:00

abstract：:In the last few years, molecular studies on pituitary adenomas have yielded evidence supporting a primary pituitary origin of these tumors. Although the existence of genomic alterations in tumoral cells is strongly suggested by the fact that almost all pituitary adenomas are monoclonal in origin, structural genetic ab...

journal_title：European journal of endocrinology

authors： Spada A,Vallar L,Faglia G

更新日期：1994-01-01 00:00:00

abstract：CONTEXT AND OBJECTIVE:Adipokines are involved in the etiopathology of obesity-related disorders. Since the role of adipokine retinol-binding protein-4 (RBP4) in obesity remains uncertain and its relationship with other adipokines and inflammatory markers has not been examined in detail, we investigated the relationship...

journal_title：European journal of endocrinology

authors： Broch M,Auguet MT,Ramírez R,Olona M,Aguilar C,Megia A,Alcaide MJ,Pastor R,Martínez S,Caubet E,Garcia-España A,Richart C

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To assess whether TCF7L2 single nucleotide polymorphisms rs7903146 C/T and rs11196236 C/T are associated with polycystic ovary syndrome (PCOS) in South Brazilian women. DESIGN:Cross-sectional study. METHODS:Two hundred PCOS patients and 102 non-hirsute, ovulatory controls were genotyped by real-time PCR. Ha...

journal_title：European journal of endocrinology

authors： Ramos RB,Wiltgen D,Spritzer PM

更新日期：2013-10-01 00:00:00

abstract：CONTEXT AND OBJECTIVE:The precise diagnosis of partially virilised women with 46,XY disorders of sex development (DSD) is often obscure. In practice, this group often comes under the poorly defined, clinically based label of partial androgen insensitivity syndrome (PAIS). In a previous study, we found that 5α-reductase...

journal_title：European journal of endocrinology

authors： Phelan N,Williams EL,Cardamone S,Lee M,Creighton SM,Rumsby G,Conway GS

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Mutations in HESX1 represent a rare cause of GH deficiency (GHD) associated with a broad spectrum of other anomalies. We searched for causative mutations in a cohort of 244 Italian patients affected by combined and isolated GHD (IGHD). METHODS:The HESX1 gene-coding region and exon-intron boundaries were scre...

journal_title：European journal of endocrinology

authors： Vivenza D,Godi M,Faienza MF,Mellone S,Moia S,Rapa A,Petri A,Bellone S,Riccomagno S,Cavallo L,Giordano M,Bona G

更新日期：2011-05-01 00:00:00

abstract：:Deflazacort is an oxazoline derivative of cortisone with presumably less serious side effects, but its effects on growth factors are unknown. The present experiments in Long Evans rats were carried out to investigate how deflazacort administration affected the growing rat, especially in relation to hepatic insulin-lik...

journal_title：European journal of endocrinology

authors： Latta K,Krieg RJ Jr,Chan W,Hisano S,Chan JC

更新日期：1994-12-01 00:00:00

abstract：Objective:Several clinical studies have reported that renal impairments are sometimes observed in patients with primary aldosteronism (PA). We analyzed the prevalence of renal impairments in PA patients and identified parameters that increase the risk for them. Design:This is a retrospective cross-sectional study. We ...

journal_title：European journal of endocrinology

authors： Kawashima A,Sone M,Inagaki N,Takeda Y,Itoh H,Kurihara I,Umakoshi H,Ichijo T,Katabami T,Wada N,Ogawa Y,Kawashima J,Fujita M,Miyauchi S,Okamura S,Fukuoka T,Yanase T,Izawa S,Yoshikawa Y,Hashimoto S,Yamada M,Kai T,

更新日期：2019-09-01 00:00:00

abstract：:Systematic studies of autosomal dominant osteopetrosis (ADO) were followed by the identification of underlying mutations giving unique possibilities to perform translational studies. What was previously designated ADO1 turned out to be a high bone mass phenotype caused by a missense mutation in the first propeller of ...

journal_title：European journal of endocrinology

authors： Bollerslev J,Henriksen K,Nielsen MF,Brixen K,Van Hul W

更新日期：2013-07-13 00:00:00

abstract：:Acromegaly is associated with high morbidity and elevated mortality when not adequately treated. Surgery is the first-line treatment for most patients as it is the only one that can lead to immediate cure. In patients who are not cured by surgery, treatment is currently based on a trial-and-error approach. First-gener...

journal_title：European journal of endocrinology

authors： Kasuki L,Wildemberg LE,Gadelha MR

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:The fetus is most vulnerable to severe iodine deficiency and hypothyroidism during pregnancy. The effects of mild iodine deficiency and subclinical hypothyroidism are poorly known. The present study assesses the association between thyroid hormones (TH)s and urinary iodine concentration (UIC) in healthy pr...

journal_title：European journal of endocrinology

authors： Alvarez-Pedrerol M,Guxens M,Mendez M,Canet Y,Martorell R,Espada M,Plana E,Rebagliato M,Sunyer J

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:Thyroid function parameters have been associated with obesity, but associations with the type of adiposity have not been examined. We used ultrasound (US) to assess regional adiposity and investigated associations of thyroid function with parameters of central obesity. DESIGN:Cross-sectional study. METHODS:...

journal_title：European journal of endocrinology

authors： Alevizaki M,Saltiki K,Voidonikola P,Mantzou E,Papamichael C,Stamatelopoulos K

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Biallelic TSHR mutations cause congenital hypothyroidism (CH). Serum TSH levels of monoallelic mutation carriers range from normal to mildly elevated, and thus the size of its effect remains unclear. The objectives were to examine the association between monoallelic TSHR mutations and positivity at newborn sc...

journal_title：European journal of endocrinology

authors： Abe K,Narumi S,Suwanai AS,Adachi M,Muroya K,Asakura Y,Nagasaki K,Abe T,Hasegawa T

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:The French Acromegaly Registry records data of acromegalic patients' since 1992 in French, Belgian (Liège), and Swiss (Lausanne) centers. We studied the prevalence of diabetes in this population looking for risk factors. Patients from one of the centers (Reims) were then analyzed more thoroughly. METHODS:Th...

journal_title：European journal of endocrinology

authors： Fieffe S,Morange I,Petrossians P,Chanson P,Rohmer V,Cortet C,Borson-Chazot F,Brue T,Delemer B,French Acromegaly Registry.

更新日期：2011-06-01 00:00:00

abstract：CONTEXT:Although combination therapy of acromegaly with long-acting somatostatin analogs (LA-SSAs) and pegvisomant (PEGV) normalizes insulin-like growth factor-1 (IGF1) levels in the majority of patients, it requires long-term adherence. Switching from combination therapy to monotherapy with weekly PEGV could improve p...

journal_title：European journal of endocrinology

authors： Muhammad A,van der Lely AJ,O'Connor RD,Delhanty PJ,Dal J,Dallenga AH,Feelders RA,Janssen JA,Jorgensen JO,Neggers SJ

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:Herpes simplex virus type 1 (HSV-1)-derived vectors are known to be effective tools to deliver transgenes into normal and neoplastic anterior pituitary (AP) cells in vitro. Our objective was to assess the in vitro and in vivo effects of tsK/beta-gal, a temperature-sensitive HSV-1-derived vector harbouring the...

journal_title：European journal of endocrinology

authors： Bolognani F,Albariño C,Romanowski V,Carri NG,Goya RG

更新日期：2001-10-01 00:00:00

abstract：:Approximately 15 million babies are born preterm across the world every year, with less than 37 completed weeks of gestation. Survival rates increased during the last decades with the improvement of neonatal care. With premature birth, babies are deprived of the intense intrauterine growth phase, and postnatal growth ...

journal_title：European journal of endocrinology

authors： Boguszewski MCDS,Cardoso-Demartini AA

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To investigate the association between plasma vitamin D (VD) levels and histological liver damage in children with nonalcoholic fatty liver disease (NAFLD). SUBJECTS AND METHODS:In this cross-sectional study, carried out in a tertiary care center for obesity, 73 consecutive overweight and obese children with...

journal_title：European journal of endocrinology

authors： Nobili V,Giorgio V,Liccardo D,Bedogni G,Morino G,Alisi A,Cianfarani S

更新日期：2014-03-08 00:00:00