Rebound of hepatitis B virus replication in HepG2 cells after cessation of antiviral treatment.

abstract：:The genome of a human papillomavirus (HPV) found in a patient with Bowen's disease of the skin was molecularly cloned. Blot hybridization experiments, performed under stringent conditions, revealed no cross-hybridization between this HPV DNA and the other known HPV DNAs, showing that this HPV represents a new type, te...

journal_title：Journal of virology

authors： Kawashima M,Jablonska S,Favre M,Obalek S,Croissant O,Orth G

更新日期：1986-02-01 00:00:00

abstract：:The RNA elements that are required for replication of defective interfering (DI) RNA of the JHM strain of mouse hepatitis virus (MHV) consist of three discontinuous genomic regions: about 0.46 to 0.47 kb from both terminal sequences and an internal 58-nucleotide (nt)-long sequence (58-nt region) present at about 0.9 k...

journal_title：Journal of virology

authors： Repass JF,Makino S

更新日期：1998-10-01 00:00:00

abstract：:Fowl adenovirus serotype 4 (FAdV-4) is a hepatotropic virus that causes severe hepatic damage characterized by basophilic intranuclear inclusion bodies, vacuolar degeneration, and multifocal necrosis in hepatocytes. Many aspects of FAdV-4 infection and pathogenesis, however, remain unknown. Here, we found that FAdV-4-...

journal_title：Journal of virology

authors： Yuan F,Hou L,Wei L,Quan R,Wang J,Liu H,Liu J

更新日期：2020-12-23 00:00:00

abstract：:The simian picornaviruses were isolated from various primate tissues during the development of general tissue culture methods in the 1950s to 1970s or from specimens derived from primates used in biomedical research. Twenty simian picornavirus serotypes are recognized, and all are presently classified within the Enter...

journal_title：Journal of virology

authors： Oberste MS,Maher K,Pallansch MA

更新日期：2002-02-01 00:00:00

abstract：:Physiological microenvironments such as blood, seminal plasma, mucosal secretions, or lymphatic fluids may influence the biology of the virus-host cell and immune interactions for human immunodeficiency virus type 1 (HIV-1). Relative to media, physiological levels of human plasma were found to enhance the infectivity ...

journal_title：Journal of virology

authors： Wu SC,Spouge JL,Conley SR,Tsai WP,Merges MJ,Nara PL

更新日期：1995-10-01 00:00:00

abstract：:The gene encoding the glycoprotein Marek's disease herpesvirus A antigen (MDHV-A) precursor polypeptide pr47 was delineated by using Northern blot (RNA blot) analysis and hybrid selection of its mRNA with cloned MDHV DNA, cell-free translation of the mRNA, and immunoprecipitation of the polypeptide. The resulting piec...

journal_title：Journal of virology

authors： Isfort RJ,Kung HJ,Velicer LF

更新日期：1987-08-01 00:00:00

abstract：:The wild-type strain of vesicular stomatitis virus (VSV) contains in its complete virion (VSV-1, B particles) a minus strand RNA. The principle defective particle of the wild-type strain (VSV-111, T particles) contains a shorter minus strand, homologous to part of the VSV-1 genome. Neither virion contains any detectab...

journal_title：Journal of virology

authors： Roy P,Repik P,Hefti E,Bishop DH

更新日期：1973-06-01 00:00:00

abstract：:The virion RNA of Moloney murine leukemia virus (MuLV) has been translated in eukaryotic cell-free systems derived from mouse L- and human HeLa cells. In both systems at least three polypeptides, approximately 60,000, 70,000, and 180,000 in apparent molecular weight, were formed in response to the added 35S MuLV RNA. ...

journal_title：Journal of virology

authors： Kerr IM,Olshevsky U,Lodish HF,Baltimore D

更新日期：1976-05-01 00:00:00

abstract：:Despite intensive research on the identification of T-cell epitopes in cattle after foot-and-mouth disease virus (FMDV) infection during the last 20 years, knowledge of major histocompatibility complex (MHC) restriction and anchor residues of such epitopes is still sparse. Therefore, as a first step, we tested lymphoc...

journal_title：Journal of virology

authors： Gerner W,Hammer SE,Wiesmüller KH,Saalmüller A

更新日期：2009-05-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the most important cause of severe, lower respiratory tract infections in infants, and RSV infections have been associated with chronic wheezing and asthma during childhood. However, the mechanism of RSV-induced airway inflammation and airway hyperresponsiveness (AHR) is poorly und...

journal_title：Journal of virology

authors： Zang N,Xie X,Deng Y,Wu S,Wang L,Peng C,Li S,Ni K,Luo Y,Liu E

更新日期：2011-12-01 00:00:00

abstract：:Incorporation of human immunodeficiency virus type 1 (HIV-1) envelope proteins into vesicular stomatitis virus (VSV) particles was studied in a system that allows expressed envelope proteins to rescue phenotypically a temperature-sensitive mutant of VSV (tsO45). This mutant exhibits defective transport of its own enve...

journal_title：Journal of virology

authors： Owens RJ,Rose JK

更新日期：1993-01-01 00:00:00

abstract：:Attempts to elicit broadly neutralizing antibody responses by human immunodeficiency virus type 1 (HIV-1) vaccine antigens have been met with limited success. To better understand the requirements for cross-neutralization of HIV-1, we have characterized the neutralizing antibody specificities present in the sera of th...

journal_title：Journal of virology

authors： Dhillon AK,Donners H,Pantophlet R,Johnson WE,Decker JM,Shaw GM,Lee FH,Richman DD,Doms RW,Vanham G,Burton DR

更新日期：2007-06-01 00:00:00

abstract：:Recent studies have revealed that innate immunity is involved in the development of adaptive immune responses; however, its role in protection is not clear. In order to elucidate the exact role of Toll-like receptor (TLR) or RIG-I-like receptor (RLR) signaling on immunogenicity and protective efficacy against influenz...

journal_title：Journal of virology

authors： Seo SU,Kwon HJ,Song JH,Byun YH,Seong BL,Kawai T,Akira S,Kweon MN

更新日期：2010-12-01 00:00:00

abstract：:Cellular responses to DNA damage are crucial for maintaining genome integrity, virus infection, and preventing the development of cancer. Hepatitis C virus (HCV) infection and the expression of the HCV nonstructural protein NS3 and core protein have been proposed as factors involved in the induction of double-stranded...

journal_title：Journal of virology

authors： Ariumi Y,Kuroki M,Dansako H,Abe K,Ikeda M,Wakita T,Kato N

更新日期：2008-10-01 00:00:00

abstract：:The retroviral restriction factor TRIMCyp, derived from the TRIM5 gene, blocks replication at a postentry step. TRIMCyp has so far been found in four species of Asian macaques, Macaca fascicularis, M. mulatta, M. nemestrina, and M. leonina. M. fascicularis is commonly used as a model for AIDS research, but TRIMCyp has...

journal_title：Journal of virology

authors： Dietrich EA,Brennan G,Ferguson B,Wiseman RW,O'Connor D,Hu SL

更新日期：2011-10-01 00:00:00

abstract：:Certain murine leukemia viruses (MLVs) can induce progressive noninflammatory spongiform neurodegeneration similar to that caused by prions. The primary MLV determinants responsible have been mapped to within the env gene; however, it has remained unclear how env mediates disease, whether non-Env viral components are ...

journal_title：Journal of virology

authors： Li Y,Cardona SM,Traister RS,Lynch WP

更新日期：2011-03-01 00:00:00

abstract：:Hepatitis B virus (HBV) DNA clones were propagated from 57 carriers with antibody to hepatitis B e antigen (HBeAg) and sequenced within nucleotides (nt) 1685 to 1926 including the core promoter (nt 1742 to 1849) and the pre-C region (nt 1814 to 1900). Mutations in the core promoter or those in the pre-C region, or bot...

journal_title：Journal of virology

authors： Okamoto H,Tsuda F,Akahane Y,Sugai Y,Yoshiba M,Moriyama K,Tanaka T,Miyakawa Y,Mayumi M

更新日期：1994-12-01 00:00:00

abstract：:Virion protein 16 (VP16) of herpes simplex virus type 1 (HSV-1) is a potent transcriptional activator of viral immediate-early (IE) genes. The VP16 activation domain can recruit various transcriptional coactivators to target gene promoters. However, the role of transcriptional coactivators in HSV-1 IE gene expression ...

journal_title：Journal of virology

authors： Kutluay SB,DeVos SL,Klomp JE,Triezenberg SJ

更新日期：2009-04-01 00:00:00

abstract：:Cells of Mus minutoides, an African pygmy mouse of the subgenus Nannomys, are susceptible to ecotropic Moloney and Friend mouse leukemia viruses (MLVs) but not to AKV-type MLVs. Transfected MA139 ferret cells expressing the mCAT-1 cell surface receptor, with the minCAT-1 substitutions K222Q and V233L, did not restrict...

journal_title：Journal of virology

authors： Yan Y,Kozak CA

更新日期：2008-07-01 00:00:00

abstract：:The human T-cell leukemia virus type 1 Tax protein activates the expression of cellular immediate early genes controlled by the serum response element (SRE), which contains both the serum response factor (SRF) binding element (CArG box) and the ternary complex factor (TCF) binding element (Ets box). We show that TCF b...

journal_title：Journal of virology

authors： Shuh M,Derse D

更新日期：2000-12-01 00:00:00

abstract：:Infection of the chestnut blight fungus Cryphonectria parasitica with Cryphonectria hypovirus 1 (CHV1) causes disruption of virulence, pigmentation, and sporulation. Transcriptional downregulation of key developmentally regulated fungal genes occurs during infection, but vegetative growth is unaffected. Previous studi...

journal_title：Journal of virology

authors： Kazmierczak P,McCabe P,Turina M,Jacob-Wilk D,Van Alfen NK

更新日期：2012-06-01 00:00:00

abstract：:The recent identification of coreceptors that mediate efficient entry of human immunodeficiency virus type 1 (HIV-1) suggests new therapeutic and preventive strategies. We analyzed simian immunodeficiency virus (SIV) entry cofactors to investigate whether the macaque SIV model can be used as an experimental model to e...

journal_title：Journal of virology

authors： Kirchhoff F,Pöhlmann S,Hamacher M,Means RE,Kraus T,Uberla K,Di Marzio P

更新日期：1997-09-01 00:00:00

abstract：:ZAM is an env-containing member of the gypsy family of retrotransposons that represents a possible retrovirus of invertebrates. In this paper, we traced ZAM mobilization to get information about a potential path a retroelement may take to reach the germ line of its host. In situ hybridization on whole-mount tissues an...

journal_title：Journal of virology

authors： Leblanc P,Desset S,Giorgi F,Taddei AR,Fausto AM,Mazzini M,Dastugue B,Vaury C

更新日期：2000-11-01 00:00:00

abstract：:The envelope glycoprotein (GP) of lymphocytic choriomeningitis virus (LCMV) is posttranslationally cleaved into two subunits. We show here that this endoproteolytic processing is not required for transport to the cell surface but is essential for LCMV GP to mediate infectivity of pseudotyped retroviral vectors. By sys...

journal_title：Journal of virology

authors： Beyer WR,Pöpplau D,Garten W,von Laer D,Lenz O

更新日期：2003-03-01 00:00:00

abstract：:T-antigen-induced DNA distortion was studied in a series of simian virus 40 (SV40) plasmid constructs whose relative replication efficiency ranges from 0.2 to 36. Bending was detected in the wild-type SV40 regulatory region consisting of three copies of the GC-rich 21-bp repeat but not in constructs with only one or t...

journal_title：Journal of virology

authors： Okuley S,Call M,Mitchell T,Hu B,Woodworth ME

更新日期：2003-10-01 00:00:00

abstract：UNLABELLED:The increasing prevalence of ranavirus (RV; Iridoviridae) infections of wild and commercially maintained aquatic species is raising considerable concerns. While Xenopus laevis is the leading model for studies of immunity to RV, amphibian antiviral interferon (IFN) responses remain largely uncharacterized. Ac...

journal_title：Journal of virology

authors： Grayfer L,De Jesús Andino F,Robert J

更新日期：2014-05-01 00:00:00

abstract：UNLABELLED:Since the 1960s, simian hemorrhagic fever virus (SHFV; Nidovirales, Arteriviridae) has caused highly fatal outbreaks of viral hemorrhagic fever in captive Asian macaque colonies. However, the source(s) of these outbreaks and the natural reservoir(s) of this virus remain obscure. Here we report the identifica...

journal_title：Journal of virology

authors： Bailey AL,Lauck M,Sibley SD,Pecotte J,Rice K,Weny G,Tumukunde A,Hyeroba D,Greene J,Correll M,Gleicher M,Friedrich TC,Jahrling PB,Kuhn JH,Goldberg TL,Rogers J,O'Connor DH

更新日期：2014-11-01 00:00:00

abstract：:Adenovirus has a linear, double-stranded DNA genome that is perceived by the cellular Mre11-Rad50-Nbs1 (MRN) DNA repair complex as a double-strand break. If unabated, MRN elicits a double-strand break repair response that blocks viral DNA replication and ligates the viral genomes into concatemers. There are two sets o...

journal_title：Journal of virology

authors： Karen KA,Hearing P

更新日期：2011-05-01 00:00:00

abstract：:The interaction of the mouse hepatitis virus (MHV) nucleocapsid protein (N) and viral RNA was examined. Monoclonal antibody specific for N protein coimmunoprecipitated MHV genomic RNA as well as all six MHV subgenomic mRNAs found in MHV-infected cells. In contrast, monoclonal antibodies to the MHV E2 or E1 envelope gl...

journal_title：Journal of virology

authors： Baric RS,Nelson GW,Fleming JO,Deans RJ,Keck JG,Casteel N,Stohlman SA

更新日期：1988-11-01 00:00:00

abstract：:Previous in vitro analyses have shown that the human immunodeficiency virus type 1 (HIV-1) integrase uses either manganese or magnesium to assemble as a stable complex on the donor substrate and to catalyze strand transfer. We now demonstrate that subsequent to assembly, catalysis of both 3' end processing and strand ...

journal_title：Journal of virology

authors： Hazuda DJ,Felock PJ,Hastings JC,Pramanik B,Wolfe AL

更新日期：1997-09-01 00:00:00