A random effects variance shift model for detecting and accommodating outliers in meta-analysis.

abstract：BACKGROUND:The prevalence of Chronic Obstructive Pulmonary Disease (COPD) in many developed countries appears to be increasing. There is some evidence from Latin America that COPD is a growing cause of death, but information on prevalence is scant. It is possible that, due to the high frequency of smoking in these coun...

journal_title：BMC medical research methodology

authors： Menezes AM,Victora CG,Perez-Padilla R,PLATINO Team.

更新日期：2004-06-17 00:00:00

abstract：BACKGROUND:Dynamic risk models, which incorporate disease-free survival and repeated measurements over time, might yield more accurate predictions of future health status compared to static models. The objective of this study was to develop and apply a dynamic prediction model to estimate the risk of developing type 2 ...

journal_title：BMC medical research methodology

authors： Parast L,Mathews M,Friedberg MW

更新日期：2019-08-14 00:00:00

abstract：BACKGROUND:Video stimulated recall (VSR) is a method of enhancing participants' accounts of the consultation using a video recording of the event to encourage and prompt recall in a post consultation interview. VSR is used in education and education research, and to a lesser extent in medical and nursing research. Litt...

journal_title：BMC medical research methodology

authors： Paskins Z,McHugh G,Hassell AB

更新日期：2014-08-30 00:00:00

abstract：BACKGROUND:To describe how frequently harm is reported in the abstract of high impact factor medical journals. METHODS: DESIGN AND POPULATION:We carried out a blinded structured review of a random sample of 363 Randomised Controlled Trials (RCTs) carried out on human beings, and published in high impact factor medica...

journal_title：BMC medical research methodology

authors： Bernal-Delgado E,Fisher ES

更新日期：2008-03-27 00:00:00

abstract：BACKGROUND:Compliance is a critical issue for parental questionnaires in school based epidemiological surveys and high compliance is difficult to achieve. The objective of this study was to determine trends and factors associated with parental questionnaire compliance during respiratory health surveys of school childre...

journal_title：BMC medical research methodology

authors： Koshy G,Brabin BJ

更新日期：2012-04-20 00:00:00

abstract：BACKGROUND:Diet plays an important role in chronic disease, and the use of dietary pattern analysis has grown rapidly as a way of deconstructing the complexity of nutritional intake and its relation to health. Pattern analysis methods, such as principal component analysis (PCA), have been used to investigate various di...

journal_title：BMC medical research methodology

authors： Zhang F,Tapera TM,Gou J

更新日期：2018-10-29 00:00:00

abstract：BACKGROUND:Small group research in healthcare is important because it deals with interaction and decision-making processes that can help to identify and improve safer patient treatment and care. However, the number of studies is limited due to time- and resource-intensive data processing. The aim of this study was to e...

journal_title：BMC medical research methodology

authors： Aufegger L,Bicknell C,Soane E,Ashrafian H,Darzi A

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:Randomized controlled trials are the gold-standard for clinical trials. However, randomization is not always feasible. In this article we propose a prospective and adaptive matched case-control trial design assuming that a control group already exists. METHODS:We propose and discuss an interim analysis step...

journal_title：BMC medical research methodology

authors： Weber D,Uhlmann L,Schönenberger S,Kieser M

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:Randomised controlled trials (RCTs) are the gold standard for evidence-based practice. However, RCTs can have limitations. For example, translation of findings into practice can be limited by design features, such as inclusion criteria, not accurately reflecting clinical populations. In addition, it is expen...

journal_title：BMC medical research methodology

authors： Lemanska A,Byford RC,Cruickshank C,Dearnaley DP,Ferreira F,Griffin C,Hall E,Hinton W,de Lusignan S,Sherlock J,Faithfull S

更新日期：2020-07-25 00:00:00

abstract：BACKGROUND:There is increasing awareness that meta-analyses require a sufficiently large information size to detect or reject an anticipated intervention effect. The required information size in a meta-analysis may be calculated from an anticipated a priori intervention effect or from an intervention effect suggested b...

journal_title：BMC medical research methodology

authors： Wetterslev J,Thorlund K,Brok J,Gluud C

更新日期：2009-12-30 00:00:00

abstract：BACKGROUND:Evidence mapping describes the quantity, design and characteristics of research in broad topic areas, in contrast to systematic reviews, which usually address narrowly-focused research questions. The breadth of evidence mapping helps to identify evidence gaps, and may guide future research efforts. The Globa...

journal_title：BMC medical research methodology

authors： Bragge P,Clavisi O,Turner T,Tavender E,Collie A,Gruen RL

更新日期：2011-06-17 00:00:00

abstract：BACKGROUND:A recent paper found that terminal digits of statistical values in Nature deviated significantly from an equiprobable distribution, indicating errors or inconsistencies in rounding. This finding, as well as the discovery that a large percentage of p values were inconsistent with reported test statistics, led...

journal_title：BMC medical research methodology

authors： Jeng M

更新日期：2006-09-13 00:00:00

abstract：BACKGROUND:Thresholds for statistical significance are insufficiently demonstrated by 95% confidence intervals or P-values when assessing results from randomised clinical trials. First, a P-value only shows the probability of getting a result assuming that the null hypothesis is true and does not reflect the probabilit...

journal_title：BMC medical research methodology

authors： Jakobsen JC,Gluud C,Winkel P,Lange T,Wetterslev J

更新日期：2014-03-04 00:00:00

abstract：BACKGROUND:Although a variety of instruments are available that capture stress experience, the assessment of chronic stress has been hindered by the lack of economical screening instruments. Recently, an English-language version of the Trier Inventory for Chronic Stress (TICS-EN) consisting of 57 items according to a s...

journal_title：BMC medical research methodology

authors： Petrowski K,Braehler E,Schmalbach B,Hinz A,Bastianon C,Ritz T

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND:Mediation is an important issue considered in the behavioral, medical, and social sciences. It addresses situations where the effect of a predictor variable X on an outcome variable Y is explained to some extent by an intervening, mediator variable M. Methods for addressing mediation have been available for ...

journal_title：BMC medical research methodology

authors： Knafl GJ,Knafl KA,Grey M,Dixon J,Deatrick JA,Gallo AM

更新日期：2017-03-21 00:00:00

abstract：BACKGROUND:Polypharmacy can be either beneficial or harmful to children. We conducted a scoping review to examine the concept of pediatric polypharmacy: its definition, prevalence, extent and gaps in research. In this manuscript, we report our transdisciplinary scoping review methodology. METHODS:After establishing a ...

journal_title：BMC medical research methodology

authors： Bakaki PM,Staley J,Liu R,Dawson N,Golchin N,Horace A,Johnson H,Waldron J,Winterstein A,Kleinman LC,Bolen SD

更新日期：2018-10-04 00:00:00

abstract：BACKGROUND:Sero- prevalence studies often have a problem of missing data. Few studies report the proportion of missing data and even fewer describe the methods used to adjust the results for missing data. The objective of this review was to determine the analytical methods used for analysis in HIV surveys with missing ...

journal_title：BMC medical research methodology

authors： Mosha NR,Aluko OS,Todd J,Machekano R,Young T

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:Spiritual care is defined as recognizing and responding to the needs of the human spirit when the individual is facing trauma, illness, or sadness. Providing spiritual care is one of the core aspects of holistic care, as it is significantly associated with patients' quality of life. The provision of optimal ...

journal_title：BMC medical research methodology

authors： Hu Y,Tiew LH,Li F

更新日期：2019-01-23 00:00:00

abstract：BACKGROUND:Multistate models have become increasingly useful to study the evolution of a patient's state over time in intensive care units ICU (e.g. admission, infections, alive discharge or death in ICU). In addition, in critically-ill patients, data come from different ICUs, and because observations are clustered int...

journal_title：BMC medical research methodology

authors： Liquet B,Timsit JF,Rondeau V

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Standard random-effects meta-analysis methods perform poorly when applied to few studies only. Such settings however are commonly encountered in practice. It is unclear, whether or to what extent small-sample-size behaviour can be improved by more sophisticated modeling. METHODS:We consider likelihood-based...

journal_title：BMC medical research methodology

authors： Seide SE,Röver C,Friede T

更新日期：2019-01-11 00:00:00

abstract：BACKGROUND:The Public Population Project in Genomics (P3G) is an organisation that aims to promote collaboration between researchers in the field of population-based genomics. The main objectives of P3G are to encourage collaboration between researchers and biobankers, optimize study design, promote the harmonization o...

journal_title：BMC medical research methodology

authors： Bennett DA,Little J,Masson LF,Minelli C

更新日期：2011-10-05 00:00:00

abstract：BACKGROUND:Sickness absence (SA) is an important social, economic and public health issue. Identifying and understanding the determinants, whether biological, regulatory or, health services-related, of variability in SA duration is essential for better management of SA. The conditional frailty model (CFM) is useful whe...

journal_title：BMC medical research methodology

authors： Torá-Rocamora I,Gimeno D,Delclos G,Benavides FG,Manzanera R,Jardí J,Alberti C,Yasui Y,Martínez JM

更新日期：2013-09-16 00:00:00

abstract：BACKGROUND:The aim of this study was to examine the relationship between mortality and statin adherence using two different approaches to adherence measurement (summary versus repeated-measures). METHODS:A retrospective cohort study was conducted using administrative data from Saskatchewan, Canada between 1994 and 200...

journal_title：BMC medical research methodology

authors： Alsabbagh MW,Eurich D,Lix LM,Wilson TW,Blackburn DF

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:Primary care databases are a major source of data for epidemiological and health services research. However, most studies are based on coded information, ignoring information stored in free text. Using the early presentation of rheumatoid arthritis (RA) as an exemplar, our objective was to estimate the exten...

journal_title：BMC medical research methodology

authors： Ford E,Nicholson A,Koeling R,Tate A,Carroll J,Axelrod L,Smith HE,Rait G,Davies KA,Petersen I,Williams T,Cassell JA

更新日期：2013-08-21 00:00:00

abstract：BACKGROUND:Studies in both paediatric and psychiatric settings often experience problems in recruitment. This can compromise the ability of the study to recruit to target, meaning studies are potentially underpowered. It can also result in a biased sample if a non-representative group are selectively recruited. Recruit...

journal_title：BMC medical research methodology

authors： Loades ME,Smith L,Higson-Sweeney N,Beasant L,Stallard P,Kessler D,Crawley E

更新日期：2019-04-27 00:00:00

abstract：BACKGROUND:Emergency Departments (EDs) are a first point-of-contact for many youth with mental health and suicidality concerns and can serve as an effective recruitment source for randomized controlled trials (RCTs) of mental health interventions. However, recruitment in acute care settings is impeded by several challe...

journal_title：BMC medical research methodology

authors： Tracey M,Finkelstein Y,Schachter R,Cleverley K,Monga S,Barwick M,Szatmari P,Moretti ME,Willan A,Henderson J,Korczak DJ

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:The weighted estimators generally used for analyzing case-cohort studies are not fully efficient and naive estimates of the predictive ability of a model from case-cohort data depend on the subcohort size. However, case-cohort studies represent a special type of incomplete data, and methods for analyzing inc...

journal_title：BMC medical research methodology

authors： Marti H,Carcaillon L,Chavance M

更新日期：2012-03-09 00:00:00

abstract：BACKGROUND:Various papers have addressed pros and cons of the stepped wedge cluster randomized trial design (SWD). However, some issues have not or only limitedly been addressed. Our aim was to provide a comprehensive overview of all merits and limitations of the SWD to assist researchers, reviewers and medical ethics ...

journal_title：BMC medical research methodology

authors： de Hoop E,van der Tweel I,van der Graaf R,Moons KG,van Delden JJ,Reitsma JB,Koffijberg H

更新日期：2015-10-30 00:00:00

abstract：BACKGROUND:With the increased empirical interest in the positive significance of improving nurses' sense of professional benefits, there is a requirement for measures of nurses' perceived professional benefit (NPPB). Our objective was to develop and psychometrically test a brief Nurses' Perceived Professional Benefit Q...

journal_title：BMC medical research methodology

authors： Hu Y,Hu J,Li L,Zhao B,Liu X,Li F

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:While randomised controlled trials (RCTs) provide high-quality evidence to guide practice, much routine care is not based upon available RCTs. This disconnect between evidence and practice is not sufficiently well understood. This case study explores this relationship using a novel approach. Better understan...

journal_title：BMC medical research methodology

authors： Byrne BE,Rooshenas L,Lambert HS,Blazeby JM

更新日期：2020-05-12 00:00:00