Abstract:
:The essential trace element selenium is of fundamental importance to human biology. Information on the membrane-bound selenoproteins was obtained by labeling of rats in vivo with (75)Se-selenite, subcellular fractionation of the tissue homogenates, separation of the proteins by SDS-PAGE, two-dimensional electrophoresis, and selenium detection by autoradiography. In this way, in addition to already known membrane-bound selenoproteins three novel selenoproteins in the molecular mass range of 38-40, 18, and 12-13 kDa were detected in the microsomal membranes.
journal_name
Ann N Y Acad Scijournal_title
Annals of the New York Academy of Sciencesauthors
Kyriakopoulos A,Bertelsmann H,Graebert A,Hoppe B,Kuhbacher M,Behne Ddoi
10.1111/j.1749-6632.2002.tb04652.xsubject
Has Abstractpub_date
2002-11-01 00:00:00pages
289-92eissn
0077-8923issn
1749-6632journal_volume
973pub_type
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