Ambulatory polysomnography of never-depressed borderline subjects: a high-risk approach to rapid eye movement latency.

Abstract:

:The sleep parameters of never-depressed borderline subjects and age- and sex-matched normal controls were compared by continuous 48-hr ambulatory electroencephalographic (EEG) monitoring. Borderline subjects had a significantly shorter rapid eye movement latency, normal architecture of rapid eye movements sleep, and had familial risks for mood disorders four times greater than in the families of controls. Reduced latency of rapid eye movement can be a trait indicator of liability to depression, present before the clinical appearance of the disorder, and demonstrable in a putative high-risk population.

journal_name

Biol Psychiatry

journal_title

Biological psychiatry

authors

Battaglia M,Ferini-Strambi L,Smirne S,Bernardeschi L,Bellodi L

doi

10.1016/0006-3223(93)90321-4

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

326-34

issue

5

eissn

0006-3223

issn

1873-2402

pii

0006-3223(93)90321-4

journal_volume

33

pub_type

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