Insulin increases CSF Abeta42 levels in normal older adults.

abstract：BACKGROUND:Oculopharyngodistal myopathy (OPDM) has been reported as a rare, adult-onset hereditary muscle disease with putative autosomal dominant and autosomal recessive inheritance. Patients with OPDM present with progressive ocular, pharyngeal, and distal limb muscle involvement. The genetic defect causing OPDM has ...

journal_title：Neurology

authors： Durmus H,Laval SH,Deymeer F,Parman Y,Kiyan E,Gokyigiti M,Ertekin C,Ercan I,Solakoglu S,Karcagi V,Straub V,Bushby K,Lochmüller H,Serdaroglu-Oflazer P

更新日期：2011-01-18 00:00:00

abstract：OBJECTIVE:To compare access to intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) and its outcomes in patients with and without dementia. METHODS:This was a longitudinal cohort study of the Swedish dementia and stroke registries. Patients with preexisting dementia who had AIS from 2010 to 2014 (n = 1,356) ...

journal_title：Neurology

authors： Zupanic E,von Euler M,Kåreholt I,Contreras Escamez B,Fastbom J,Norrving B,Religa D,Kramberger MG,Winblad B,Johnell K,Eriksdotter M,Garcia-Ptacek S

更新日期：2017-10-31 00:00:00

abstract：OBJECTIVE:To further investigate the basis of abnormal neuromuscular transmission in two patients with congenital myasthenic syndrome associated with episodic ataxia type 2 (EA2) using stimulated single fiber EMG (SFEMG) and in vitro microelectrode studies. METHODS:Two patients with genetically characterized EA2 previ...

journal_title：Neurology

authors： Maselli RA,Wan J,Dunne V,Graves M,Baloh RW,Wollmann RL,Jen J

更新日期：2003-12-23 00:00:00

abstract：OBJECTIVE:To determine whether increased risk of acute ischemic stroke (AIS) following herpes zoster (HZ) might be modified by the status of zoster vaccine live (ZVL) vaccination and antiviral treatment following HZ. METHODS:We included 87,405 Medicare fee-for-service beneficiaries aged ≥66 years diagnosed with HZ and...

journal_title：Neurology

authors： Yang Q,George MG,Chang A,Tong X,Merritt R,Hong Y

更新日期：2020-08-11 00:00:00

abstract：:Tracheostomy has been employed to release the airway obstruction at the glottic level and to prevent sudden death in patients with multiple system atrophy (MSA). However, sudden death is possible even after tracheostomy. Nocturnal polysomnography showed that the apnea-hypopnea index became higher after tracheostomy, a...

journal_title：Neurology

authors： Jin K,Okabe S,Chida K,Abe N,Kimpara T,Ohnuma A,Nomura H,Itoyama Y,Onodera H

更新日期：2007-05-08 00:00:00

abstract：:We evaluated the ability of nurse clinicians to assess parkinsonian signs in older persons with a modified version of the motor section of the Unified Parkinson's Disease Rating Scale (UPDRS). After completing a structured training protocol, three nurse clinicians and a neurologist with expertise in movement disorders...

journal_title：Neurology

authors： Bennett DA,Shannon KM,Beckett LA,Goetz CG,Wilson RS

更新日期：1997-12-01 00:00:00

abstract：:A 35-year-old woman had cardiac arrest requiring treatment with a left ventricular assist device. After regaining consciousness, examination revealed upbeating nystagmus, otherwise normal bulbar function, left arm dysmetria, and numbness periorally and in areas she described as "a turtleneck of numbness with a T-shirt...

journal_title：Neurology

authors： Ryman DC,Ju YE

更新日期：2013-12-03 00:00:00

abstract：:Eighty-one percent (47/58) of private-sector neurologists in Colorado responded to a mail survey of practice patterns. We evaluated patient load, degree of principal versus consultative care, and use of neurodiagnostic tests. Broad areas of neurologic education that were perceived to have been lacking during residency...

journal_title：Neurology

authors： Franklin GM,Ringel SP,Nelson LM,DeLapp C

更新日期：1987-02-01 00:00:00

abstract：OBJECTIVE:To describe the clinical characteristics of encounters with patients misdiagnosed with multiple sclerosis (MS). METHODS:A cross-sectional Internet-based physician survey of MS specialists was performed. RESULTS:The response rate for the survey was 50.4%. Of those who responded, the majority (95%) reported h...

journal_title：Neurology

authors： Solomon AJ,Klein EP,Bourdette D

更新日期：2012-06-12 00:00:00

abstract：:Evidence suggests that untreated obstructive sleep apnea (OSA) can lead to hypertension, cardiovascular disease, and stroke. Conversely, the systemic effects of a wide variety of critical illnesses can lead to CNS dysfunction, which can precipitate respiratory failure. Reported is a patient in whom an acute encephalop...

journal_title：Neurology

authors： Dyken ME,Yamada T,Berger HA

更新日期：2003-05-27 00:00:00

abstract：BACKGROUND:Affective-motivational and sensory-discriminative aspects of pain were investigated in patients with mild to moderate Alzheimer disease (AD) and healthy elderly controls using the cold pressor test tolerance and repetitive stimuli of warmth and heat stimuli, evaluating the stimulus-response function. METHOD...

journal_title：Neurology

authors： Jensen-Dahm C,Werner MU,Jensen TS,Ballegaard M,Andersen BB,Høgh P,Waldemar G

更新日期：2015-04-14 00:00:00

abstract：OBJECTIVE:To examine whether prior statin use affects outcome and intracranial hemorrhage (ICH) rates in stroke patients receiving IV thrombolysis (IVT). METHODS:In a pooled observational study of 11 IVT databases, we compared outcomes between statin users and nonusers. Outcome measures were excellent 3-month outcome ...

journal_title：Neurology

authors： Engelter ST,Soinne L,Ringleb P,Sarikaya H,Bordet R,Berrouschot J,Odier C,Arnold M,Ford GA,Pezzini A,Zini A,Rantanen K,Rocco A,Bonati LH,Kellert L,Strbian D,Stoll A,Meier N,Michel P,Baumgartner RW,Leys D,Tatlisum

更新日期：2011-08-30 00:00:00

abstract：:This is a report on hepatic adverse events associated with dantrolene therapy. All cases reported to the manufacturer are included, from all sources, through 1987. Of 122 cases containing sufficient data to analyze, 47 patients had asymptomatic transaminase elevations, 12 had additional mild (less than or equal to 2.5...

journal_title：Neurology

authors： Chan CH

更新日期：1990-09-01 00:00:00

abstract：:We used the Mayo Clinic medical records linkage system to detect all cases of intracranial vascular malformation (IVM) among residents of Olmsted County, Minnesota from 1965 to 1992 and found 48 IVMs over the 27-year period, including four patients with IVM detected at autopsy, without prior symptoms. Twenty-nine of 4...

journal_title：Neurology

authors： Brown RD Jr,Wiebers DO,Torner JC,O'Fallon WM

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:To investigate the role of alcohol as a causal factor for intracerebral hemorrhage (ICH) and whether its effects might vary according to the pathogenic mechanisms underlying cerebral bleeding. METHODS:We performed a case-control analysis, comparing a cohort of consecutive white patients with ICH aged 55 year...

journal_title：Neurology

authors： Costa P,Grassi M,Iacoviello L,Zedde M,Marcheselli S,Silvestrelli G,DeLodovici ML,Sessa M,Zini A,Paciaroni M,Azzini C,Gamba M,Del Sette M,Toriello A,Gandolfo C,Bonifati DM,Tassi R,Cavallini A,Chiti A,Calabrò RS,Gri

更新日期：2018-07-17 00:00:00

abstract：BACKGROUND:Some patients with prosopagnosia have covert recognition, meaning that they retain some familiarity or knowledge of facial identity of which they are not aware. OBJECTIVE:To test the hypothesis that prosopagnosic patients with right occipitotemporal lesions and impaired face perception lack covert processin...

journal_title：Neurology

authors： Barton JJ,Cherkasova M,O'Connor M

更新日期：2001-10-09 00:00:00

abstract：OBJECTIVE:In children with sickle cell disease (SCD), silent cerebral infarcts are the most frequent cause of neurologic injury. We determined the sensitivity and specificity of selective neurocognitive measures when separating children with silent cerebral infarcts and SCD from sibling controls. Additionally, we teste...

journal_title：Neurology

authors： DeBaun MR,Schatz J,Siegel MJ,Koby M,Craft S,Resar L,Chu JY,Launius G,Dadash-Zadeh M,Lee RB,Noetzel M

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:Quality of neurologic emergency management in an under-resourced country may be improved by standard operating procedures (SOPs). METHODS:Neurologic SOPs were implemented in a large urban (Banjul) and a small rural (Brikama) hospital in the Gambia. As quality indicators of neurologic emergency management, pe...

journal_title：Neurology

authors： Jaiteh LES,Helwig SA,Jagne A,Ragoschke-Schumm A,Sarr C,Walter S,Lesmeister M,Manitz M,Blaß S,Weis S,Schlund V,Bah N,Kauffmann J,Fousse M,Kangankan S,Ramos Cabrera A,Kronfeld K,Ruckes C,Liu Y,Nyan O,Fassbender K

更新日期：2017-07-11 00:00:00

abstract：OBJECTIVES:To study the behavioral and neuroanatomic characteristics of perseverative behavior encountered on a target cancellation task in patients with neglect. METHODS:Motor perseverative behavior during line cancellation task was evaluated retrospectively in 60 patients with left hemispatial neglect from right hem...

journal_title：Neurology

authors： Na DL,Adair JC,Kang Y,Chung CS,Lee KH,Heilman KM

更新日期：1999-05-12 00:00:00

abstract：:Using an in vitro blood-nerve barrier (BNB) model, the authors tested the effect of various monoclonal antiganglioside antibodies on BNB function. Only anti-GM1 antibody significantly facilitated BNB leakage in a concentration-dependent, complement-independent manner. This study provided evidence that anti-GM1 antibod...

journal_title：Neurology

authors： Kanda T,Iwasaki T,Yamawaki M,Tai T,Mizusawa H

更新日期：2000-08-22 00:00:00

abstract：:Two adult brothers became ill within 48 hours of each other, and both had severe myoglobinuria. One brother died of oliguric renal failure. The other did not have renal failure and survived. Acute influenza A infection was documented serologically and from throat washings in the surviving brother, and by isolation of ...

journal_title：Neurology

authors： Zamkoff K,Rosen N

更新日期：1979-03-01 00:00:00

abstract：:We studied the efficacy, pharmacokinetics, and brain entry of lorazepam in the treatment of status epilepticus (SE) using a rat model of secondarily generalized convulsive SE. Lorazepam entered the bloodstream rapidly following intraperitoneal injection. Brain concentrations peaked 10 minutes after peak serum levels w...

journal_title：Neurology

authors： Walton NY,Treiman DM

更新日期：1990-06-01 00:00:00

abstract：:Immitation synkinesia is usually associated with thalamic or parietal lesions. Analysis of three cases shows that the lesions may affect the posterior columns of the spinal cord or even the peripheral nervous system. In our cases, two facts stand out, a large measure of integrity of motor activity and predominant dist...

journal_title：Neurology

authors： Cambier J,Dehen H

更新日期：1977-07-01 00:00:00

abstract：:We performed morphologic studies on regeneration of the cat's hind limb nerves, following simultaneous ligation of the aorta and right femoral artery. There were 2 regeneration patterns depending on the extent of ischemic necrosis. When nerve infarcts were limited only to intrafascicular regions, there was no basic ch...

journal_title：Neurology

authors： Korthals JK,Gieron MA,Wisniewski HM

更新日期：1989-07-01 00:00:00

abstract：:The behavioral and anatomic correlates of pure alexia were analyzed in 16 patients. Right homonymous hemianopia failed to appear in three patients, who had right achromatopsia instead. Color anomia and unilateral optic ataxia were seen in six patients. Memory defects were found in two patients. Visual agnosia was note...

journal_title：Neurology

authors： Damasio AR,Damasio H

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVE:In families with autosomal dominant partial epilepsy with auditory features (ADPEAF) with mutations in the LGI1 gene, we evaluated clustering of mutations within the gene and associations of penetrance and phenotypic features with mutation location and predicted effect (truncation or missense). METHODS:We ab...

journal_title：Neurology

authors： Ho YY,Ionita-Laza I,Ottman R

更新日期：2012-02-21 00:00:00

abstract：OBJECTIVE:To develop and evaluate a model for staging cortical amyloid deposition using PET with high generalizability. METHODS:Three thousand twenty-seven individuals (1,763 cognitively unimpaired [CU], 658 impaired, 467 with Alzheimer disease [AD] dementia, 111 with non-AD dementia, and 28 with missing diagnosis) fr...

journal_title：Neurology

authors： Collij LE,Heeman F,Salvadó G,Ingala S,Altomare D,de Wilde A,Konijnenberg E,van Buchem M,Yaqub M,Markiewicz P,Golla SSV,Wottschel V,Wink AM,Visser PJ,Teunissen CE,Lammertsma AA,Scheltens P,van der Flier WM,Boellaard R

更新日期：2020-09-15 00:00:00

abstract：:We transplanted autologous adrenal medullary tissue into the caudate nucleus of 3 patients with advanced Parkinson's disease. The 1st patient, a 59-year-old man with parkinsonian symptoms for 15 years, had mild improvement in his motor functioning after the operation. However, his postoperative course was characterize...

journal_title：Neurology

authors： Jankovic J,Grossman R,Goodman C,Pirozzolo F,Schneider L,Zhu Z,Scardino P,Garber AJ,Jhingran SG,Martin S

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between neurology inpatient satisfaction and (1) number of physicians involved in the patient's care and (2) patients' ability to identify their physicians. METHODS:A 10-item questionnaire addressing patient satisfaction and identification of physicians on the care team was admi...

journal_title：Neurology

authors： Leon Guerrero CR,Anderson T,Zazulia AR

更新日期：2018-02-13 00:00:00

abstract：:A 71-year-old man developed severe limb, bulbar, and respiratory weakness over 18 months. A muscle biopsy showed only a moderate degree of type 2 atrophy, but immunocytochemistry showed absence of chondroitin sulfate C glycosaminoglycan in the endomysium. Prednisone produced a marked increase in strength. Diffuse loss...

journal_title：Neurology

authors： al-Lozi MT,Hemelt VB,Pestronk A

更新日期：1998-02-01 00:00:00