Nerve regeneration patterns after acute ischemic injury.

abstract：:The authors conducted a randomized, double-blind, placebo-controlled, twofold crossover study in 16 patients with MS who presented with severe spasticity to investigate safety, tolerability, and efficacy of oral Delta(9)-Tetrahydrocannabinol (THC) and Cannabis sativa plant extract. Both drugs were safe, but adverse ev...

journal_title：Neurology

authors： Killestein J,Hoogervorst EL,Reif M,Kalkers NF,Van Loenen AC,Staats PG,Gorter RW,Uitdehaag BM,Polman CH

更新日期：2002-05-14 00:00:00

abstract：OBJECTIVE:To identify the source of delayed visual evoked potential (VEP) latencies in the fellow eyes of patients with optic neuritis (ON) and determine whether these latencies stem from clinically silent demyelination or reflect an adaptive process for synchronization with the affected eyes. METHODS:The study sample...

journal_title：Neurology

authors： Raz N,Chokron S,Ben-Hur T,Levin N

更新日期：2013-08-20 00:00:00

abstract：OBJECTIVE:We endeavored to develop an unruptured intracranial aneurysm (UIA) treatment score (UIATS) model that includes and quantifies key factors involved in clinical decision-making in the management of UIAs and to assess agreement for this model among specialists in UIA management and research. METHODS:An internat...

journal_title：Neurology

authors： Etminan N,Brown RD Jr,Beseoglu K,Juvela S,Raymond J,Morita A,Torner JC,Derdeyn CP,Raabe A,Mocco J,Korja M,Abdulazim A,Amin-Hanjani S,Al-Shahi Salman R,Barrow DL,Bederson J,Bonafe A,Dumont AS,Fiorella DJ,Gruber A,H

更新日期：2015-09-08 00:00:00

abstract：:A 12-year-old girl developed simple partial motor and sensory seizures due to a right perirolandic astrocytoma. Subdural EEG recording and functional stimulation disclosed close correlation between EEG-clinical manifestations of focal seizures and functional responses to cortical stimulation. This case supports the id...

journal_title：Neurology

authors： Arroyo S,Krauss GL,Lesser RP,Gordon B,Hart J Jr,Carson BS,Uematsu S

更新日期：1992-03-01 00:00:00

abstract：:In 1810, two British ships, HMS Triumph and HMS Phipps, salvaged a large load of elemental mercury from a wrecked Spanish vessel near Cadiz, Spain. The bladders containing the mercury soon ruptured. The element spread about the ships in liquid and vapor forms. The sailors presented with neurologic compromises: tremor,...

journal_title：Neurology

authors： Doherty MJ

更新日期：2004-03-23 00:00:00

abstract：:Data from three patients and 22 previously reported cases suggest that cerebral microinfarction causes a recognizable clinical syndrome. All cases present with stroke, followed by progressive dementia and often with visual field deficits, peripheral vascular disease, and signs of motor neuron dysfunction. The average ...

journal_title：Neurology

authors： Kaplan JG,Katzman R,Horoupian DS,Fuld PA,Mayeux R,Hays AP

更新日期：1985-06-01 00:00:00

abstract：:We examined serum-mediated cytotoxicity on cultured rat oligodendrocytes, using serum from patients with acute or chronic progressive multiple sclerosis and normal controls. We found heat-labile serum factors in serum from MS and also in controls. The cytotoxic effects of MS and normal sera were not restored by adding...

journal_title：Neurology

authors： Hirayama M,Lisak RP,Silberberg DH

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:To investigate the role of blocking antibodies in neonatal Guillain-Barré syndrome (GBS) occurring 12 days postpartum in a child born to a mother with ongoing GBS. METHODS:We studied plasma filtrate, purified IgG, and monovalent Fab fragments from the affected mother and serum from the neonate as well as ser...

journal_title：Neurology

authors： Buchwald B,de Baets M,Luijckx GJ,Toyka KV

更新日期：1999-10-12 00:00:00

abstract：:We studied the effects of bromocriptine on periodic limb movements in sleep (PLMS) of narcoleptic patients. Bromocriptine significantly reduced the number and index of PLMS without improving the nocturnal sleep disruption in that disorder. These results support the hypothesis that dopaminergic mechanisms are involved ...

journal_title：Neurology

authors： Boivin DB,Lorrain D,Montplaisir J

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVES:To study the effects of head injury on disease progression and on neuropathologic outcomes in amyotrophic lateral sclerosis (ALS). METHODS:Patients with ALS were surveyed to obtain head injury history, and medical records were reviewed. Linear regression was performed to determine if head injury was a predi...

journal_title：Neurology

authors： Fournier CN,Gearing M,Upadhyayula SR,Klein M,Glass JD

更新日期：2015-04-28 00:00:00

abstract：OBJECTIVE:To survey brain death criteria throughout the world. BACKGROUND:The clinical diagnosis of brain death allows organ donation or withdrawal of support. Declaration of brain death follows a certain set of examinations. The code of practice throughout the world has not been systematically investigated. METHODS:...

journal_title：Neurology

authors： Wijdicks EF

更新日期：2002-01-08 00:00:00

abstract：:Lubag (X-linked dystonia-parkinsonism) has been considered a sex-linked recessive trait and has been mapped to the pericentromeric region of the X chromosome. We studied a 54-year-old man with lubag and two of his female first cousins. Genetic typing was carried out using X chromosome markers. Fluorodopa PET was perfo...

journal_title：Neurology

authors： Waters CH,Takahashi H,Wilhelmsen KC,Shubin R,Snow BJ,Nygaard TG,Moskowitz CB,Fahn S,Calne DB

更新日期：1993-08-01 00:00:00

abstract：:We report a patient with striatonigral degeneration in whom T2-weighted MRI imaging revealed low signal and atrophy in the putamen. Neuropathologic studies confirmed putaminal atrophy and iron deposition in the MRI low signal regions. ...

journal_title：Neurology

authors： O'Brien C,Sung JH,McGeachie RE,Lee MC

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:Recent publications show that using imagery instructions, brain activation patterns indicating consciousness can be found in approximately 10% of patients with unresponsive wakefulness syndrome (UWS; previously called vegetative state). It is possible, however, that patients who cannot follow instructions (be...

journal_title：Neurology

authors： Yu T,Lang S,Vogel D,Markl A,Müller F,Kotchoubey B

更新日期：2013-01-22 00:00:00

abstract：OBJECTIVE:To clarify the clinical and neurophysiologic spectrum of myoclonus-dystonia patients with mutations of the SGCE gene. METHODS:We prospectively studied 41 consecutive patients from 22 families with documented mutations of the SGCE gene. The patients had a standardized interview, neurologic examination, and de...

journal_title：Neurology

authors： Roze E,Apartis E,Clot F,Dorison N,Thobois S,Guyant-Marechal L,Tranchant C,Damier P,Doummar D,Bahi-Buisson N,André-Obadia N,Maltete D,Echaniz-Laguna A,Pereon Y,Beaugendre Y,Dupont S,De Greslan T,Jedynak CP,Ponsot G,D

更新日期：2008-03-25 00:00:00

abstract：:We reviewed 44 cases of ischemia and infarction of the spinal cord at two university hospitals. Three patients experienced transient ischemic attacks. Etiologies of completed strokes were diverse and included rupture and surgical repair of aortic aneurysms, aortic dissection, aortic rupture and thrombosis, global isch...

journal_title：Neurology

authors： Cheshire WP,Santos CC,Massey EW,Howard JF Jr

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:To assess cerebrovascular reactivity in response to a visual task in participants with cerebral amyloid angiopathy (CAA), Alzheimer disease (AD), and mild cognitive impairment (MCI) using fMRI. METHODS:This prospective cohort study included 40 patients with CAA, 22 with AD, 27 with MCI, and 25 healthy contro...

journal_title：Neurology

authors： Switzer AR,Cheema I,McCreary CR,Zwiers A,Charlton A,Alvarez-Veronesi A,Sekhon R,Zerna C,Stafford RB,Frayne R,Goodyear BG,Smith EE

更新日期：2020-09-08 00:00:00

abstract：OBJECTIVE:Charcot-Marie-Tooth (CMT) disease is the most common inherited neuromuscular disorder, affecting 1 in 2,500 individuals. Mitochondrial DNA (mtDNA) mutations are not generally considered within the differential diagnosis of patients with uncomplicated inherited neuropathy, despite the essential requirement of ...

journal_title：Neurology

authors： Pitceathly RD,Murphy SM,Cottenie E,Chalasani A,Sweeney MG,Woodward C,Mudanohwo EE,Hargreaves I,Heales S,Land J,Holton JL,Houlden H,Blake J,Champion M,Flinter F,Robb SA,Page R,Rose M,Palace J,Crowe C,Longman C,Lu

更新日期：2012-09-11 00:00:00

abstract：OBJECTIVE:To investigate the cognitive skills of patients with relapsing remitting multiple sclerosis (RRMS), secondary progressive MS (SPMS), and primary progressive MS (PPMS) relative to healthy control subjects and to assess whether there is heterogeneity in the type of cognitive disabilities demonstrated by patient...

journal_title：Neurology

authors： Huijbregts SC,Kalkers NF,de Sonneville LM,de Groot V,Reuling IE,Polman CH

更新日期：2004-07-27 00:00:00

abstract：:Mammalian spinal cord neurons were grown in dissociated cell culture and used to study the effects of the anticonvulsant barbiturates phenobarbital and mephobarbital, and the anesthetic barbiturates pentobarbital, secobarbital, and 1,3-dimethyl-butylethyl barbituric acid on amino acid responses and neuronal membrane p...

journal_title：Neurology

authors： Macdonald RL,Barker JL

更新日期：1979-04-01 00:00:00

abstract：OBJECTIVE:This study correlated the extent of abnormalities detected by different magnetic resonance imaging (MRI) techniques [proton density (PD)-weighted, T1-weighted, and magnetization transfer imaging (MTI)] with the overall cognitive, frontal lobe, and memory impairments in patients with MS. PATIENTS:There were 3...

journal_title：Neurology

authors： Rovaris M,Filippi M,Falautano M,Minicucci L,Rocca MA,Martinelli V,Comi G

更新日期：1998-06-01 00:00:00

abstract：:The role of gender in the pathogenesis of Alzheimer's disease (AD) is an important issue that remains controversial. We compared men and women in late-onset familial AD kindreds for the risk of developing AD by studying 26 well-characterized familial AD kindreds from the Oregon Alzheimer Disease Center and, for confir...

journal_title：Neurology

authors： Payami H,Montee K,Grimslid H,Shattuc S,Kaye J

更新日期：1996-01-01 00:00:00

abstract：:The effects of acute ethanol injection on force production were measured in normal and chronic alcoholic rats. Acutely injected normal rats, acutely injected chronic alcoholic rats, and noninjected chronic alcoholic rats were compared with control groups: normal nonalcoholic rats and a dietetically deprived control gr...

journal_title：Neurology

authors： Martyn DA,Munsat TL

更新日期：1980-02-01 00:00:00

abstract：OBJECTIVE:This study explored the association between long-term epilepsy surgery outcome and changes in depressive symptoms. METHODS:Adults were enrolled between 1996 and 2001 in a multicenter prospective study to evaluate outcomes of resective epilepsy surgery. The extent of depressive symptoms and depression case st...

journal_title：Neurology

authors： Hamid H,Liu H,Cong X,Devinsky O,Berg AT,Vickrey BG,Sperling MR,Shinnar S,Langfitt JT,Walczak TS,Barr WB,Dziura J,Bazil CW,Spencer SS

更新日期：2011-11-29 00:00:00

abstract：OBJECTIVE:To assess whether exon deletions or duplications in CLCN1 are associated with recessive myotonia congenita (MC). METHODS:We performed detailed clinical and electrophysiologic characterization in 60 patients with phenotypes consistent with MC. DNA sequencing of CLCN1 followed by multiplex ligation-dependent p...

journal_title：Neurology

authors： Raja Rayan DL,Haworth A,Sud R,Matthews E,Fialho D,Burge J,Portaro S,Schorge S,Tuin K,Lunt P,McEntagart M,Toscano A,Davis MB,Hanna MG

更新日期：2012-06-12 00:00:00

abstract：:A 61-year-old woman presented with two paraneoplastic neurologic disorders--Lambert-Eaton myasthenic syndrome (LEMS) and subacute cerebellar degeneration (SCD)--that antedated the diagnosis of small-cell carcinoma of the lung by 15 months. Plasmapheresis initiated before the identification of the tumor had a beneficia...

journal_title：Neurology

authors： Blumenfeld AM,Recht LD,Chad DA,DeGirolami U,Griffin T,Jaeckle KA

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To perform a systematic review and meta-analysis of studies reporting recurrent intracranial hemorrhage (ICH) and ischemic stroke (IS) in ICH survivors with atrial fibrillation (AF) during long-term follow-up. METHODS:A comprehensive literature search including MEDLINE, EMBASE, Cochrane library, clinical tri...

journal_title：Neurology

authors： Korompoki E,Filippidis FT,Nielsen PB,Del Giudice A,Lip GYH,Kuramatsu JB,Huttner HB,Fang J,Schulman S,Martí-Fàbregas J,Gathier CS,Viswanathan A,Biffi A,Poli D,Weimar C,Malzahn U,Heuschmann P,Veltkamp R

更新日期：2017-08-15 00:00:00

abstract：OBJECTIVE:Autonomic symptoms may occur frequently in diabetic and other neuropathies. There is a need to develop a simple instrument to measure autonomic symptoms in subjects with neuropathy and to test the validity of the instrument. METHODS:The Survey of Autonomic Symptoms (SAS) consists of 11 items in women and 12 ...

journal_title：Neurology

authors： Zilliox L,Peltier AC,Wren PA,Anderson A,Smith AG,Singleton JR,Feldman EL,Alexander NB,Russell JW

更新日期：2011-03-22 00:00:00

abstract：OBJECTIVE:We hypothesized that cardiac electrical instability and abnormal autonomic tone result from cumulative cardiac injury sustained in recurrent seizures. We tested this hypothesis by comparing T-wave alternans (TWA) and heart rate variability (HRV), both established markers of sudden cardiac death (SCD) risk, in...

journal_title：Neurology

authors： Pang TD,Nearing BD,Krishnamurthy KB,Olin B,Schachter SC,Verrier RL

更新日期：2019-09-03 00:00:00

abstract：OBJECTIVE:To assess the frequency of mutations in C19orf12 in the greater neurodegeneration with brain iron accumulation (NBIA) population and further characterize the associated phenotype. METHODS:Samples from 161 individuals with idiopathic NBIA were screened, and C19orf12 mutations were identified in 23 subjects. D...

journal_title：Neurology

authors： Hogarth P,Gregory A,Kruer MC,Sanford L,Wagoner W,Natowicz MR,Egel RT,Subramony SH,Goldman JG,Berry-Kravis E,Foulds NC,Hammans SR,Desguerre I,Rodriguez D,Wilson C,Diedrich A,Green S,Tran H,Reese L,Woltjer RL,Hayfli

更新日期：2013-01-15 00:00:00