Invasive thymoma with paraneoplastic retinopathy.

abstract：:Atypical fibro-osseous lesions, usually in the proximal femur, are a common consultative diagnostic problem. This is due to the fact that they contain a variety of patterns individually reminiscent of fibrous dysplasia, fibroxanthoma (non-ossifying fibroma), myxofibroma, lipoma, cyst, bone infarct, Paget's disease, an...

journal_title：Human pathology

authors： Ragsdale BD

更新日期：1993-05-01 00:00:00

abstract：:Laminin and collagen have been studied in several tumor types and their immunomorphological expression correlated with tumor morphogenesis, local invasiveness, and metastatic behavior. In a series of 53 cases of pleomorphic adenomas (PA) and 16 cases of carcinomas ex-pleomorphic adenoma (Ca ex-PA), we investigated by ...

journal_title：Human pathology

authors： Félix A,Rosa JC,Fonseca I,Cidadão A,Soares J

更新日期：1999-08-01 00:00:00

abstract：:Abnormal nuclear megakaryocytic staining for phospho-STAT5 (pSTAT5) correlates with JAK2 V617F mutational status in non-chronic myelogenous leukemia chronic myeloproliferative disorders. However, a proportion of wild-type JAK2 non-chronic myelogenous leukemia chronic myeloproliferative disorders cases also demonstrate...

journal_title：Human pathology

authors： Gibson SE,Schade AE,Szpurka H,Bak B,Maciejewski JP,Hsi ED

更新日期：2008-07-01 00:00:00

abstract：:Pulmonary vein stenosis (PVS) is a rare disorder. Accurate diagnosis often requires anatomical examination. We report four children with pulmonary vein stenosis. Autopsy showed bilateral lesions in two patients who were thought clinically to have unilateral disease. A diagnosis of PVS was made at autopsy in the third ...

journal_title：Human pathology

authors： Sun CC,Doyle T,Ringel RE

更新日期：1995-08-01 00:00:00

abstract：:Disheveled-axin (DIX) domain containing 1 (DIXDC1), a protein containing a coiled-coil domain and a DIX domain, is involved in the progression of multiple cancers. However, the role of DIXDC1 in human pancreatic ductal adenocarcinoma (PDAC) remains unclear. In this study, we investigated the role and prognostic value ...

journal_title：Human pathology

authors： Li X,Xiao Y,Fan S,Xiao M,Wang X,Zhu X,Chen X,Li C,Zong G,Zhou G,Wan C

更新日期：2016-11-01 00:00:00

abstract：:Enteroendocrine cell dysgenesis was observed in 3 patients with intestinal failure of unknown cause. Enteroendocrine cell dysgenesis is a congenitally acquired life-threatening malabsorptive condition with a unique clinical phenotype paired with a histologically identifiable disease pattern. Two cases were first prese...

journal_title：Human pathology

authors： Cortina G,Smart CN,Farmer DG,Bhuta S,Treem WR,Hill ID,Martín MG

更新日期：2007-04-01 00:00:00

abstract：:Improved graft survival was observed in cadaver-kidney recipients prepared with random donor blood transfusions and in selected living-related-kidney recipients primed with transfusions from the kidney donor. This seems to justify a purposeful transfusion policy in these patients. ...

journal_title：Human pathology

authors： Polesky HF,Lasky LC

更新日期：1983-03-01 00:00:00

abstract：:In a series of approximately 80,000 lymph nodes, amyloid deposition was found in 18; 12 of those nodes were selected, on the basis of availability of specimens, for investigation by immunohistochemical typing to identify the protein of origin and by correlation with morphologic criteria and clinical information. Four ...

journal_title：Human pathology

authors： Newland JR,Linke RP,Lennert K

更新日期：1986-12-01 00:00:00

abstract：:Both individual patient treatment and cancer registries depend on adequate histopathology reports. To ensure the quality of these reports, professional organizations have published guidelines on minimum data sets for various cancer types. Norway has a population of 4.6 million, and all individuals have a unique identi...

journal_title：Human pathology

authors： Bjugn R,Casati B,Norstein J

更新日期：2008-03-01 00:00:00

abstract：:We used light microscopy to examine, at autopsy, bronchial arteries in three patients with cystic fibrosis who died, respectively, 10, 16, and 28 months after bronchial artery embolization with barium sulfate-impregnated polyvinyl alcohol (PVA) to control hemoptysis. PVA was not identified beyond the midsegmental bron...

journal_title：Human pathology

authors： Tomashefski JF Jr,Cohen AM,Doershuk CF

更新日期：1988-05-01 00:00:00

abstract：:A 35-year-old white Jewish homosexual man who had undergone surgery and chemotherapy for an embryonal carcinoma of the testis subsequently developed Kaposi's sarcoma. The neoplasm involved the skin as well as visceral tissues. Tissue derived from a biopsy specimen of one of the skin lesions was used in the in situ hyb...

journal_title：Human pathology

authors： Fenoglio CM,Oster MW,Lo Gerfo P,Reynolds T,Edelson R,Patterson JA,Madeiros E,McDougall JK

更新日期：1982-10-01 00:00:00

abstract：:Alpha-methyl CoA racemase (AMACR), a new molecular marker for prostate cancer, has been recently reported to be one of the most highly expressed genes in papillary renal cell carcinomas (RCCs). We tested the diagnostic usefulness of AMACR antibody in a series of 110 renal tumors: 53 papillary RCCs (33 type 1, 20 type ...

journal_title：Human pathology

authors： Molinié V,Balaton A,Rotman S,Mansouri D,De Pinieux I,Homsi T,Guillou L

更新日期：2006-06-01 00:00:00

abstract：:The aim of the current study was to test whether the grade group assessed in the index tumor nodule predicts biochemical recurrence after surgery. The study cohort series included 144 consecutive patients treated by laparoscopic radical prostatectomy. The following parameters were evaluated in each case: type of radic...

journal_title：Human pathology

authors： Vau N,Henriques V,Cheng L,Blanca A,Fonseca J,Montironi R,Cimadamore A,Lopez-Beltran A

更新日期：2019-11-01 00:00:00

abstract：:A case of thymoma with associated opportunistic infections, CD4/CD8 T-lymphocyte imbalance, low CD4-positive T-lymphocyte counts and Kaposi's sarcoma (KS) without HIV infection is reported. Cytomegalovirus inclusions were identified in the nuclei of some KS spindle and endothelial cells. It is known that KS has a high...

journal_title：Human pathology

authors： Moysset I,Lloreta J,Miguel A,Vadell C,Ribalta T,Estrach T,Serrano S

更新日期：1997-10-01 00:00:00

abstract：:Decreases in true expenses in the hospital clinical laboratory consequent to reduced utilization were estimated from four models. Each category of direct expense was adjusted according to projections and confirmed to the extent possible by actual experience. No projections of reductions in indirect expenses were made....

journal_title：Human pathology

authors： Winkelman JW

更新日期：1984-06-01 00:00:00

abstract：:We have previously shown that necrotic tumors retain their immunoreactivity for a range of cytokeratin antibodies. Some thyroid tumors undergo extensive necrosis after fine-needle aspiration (FNA) procedures. We evaluated the sensitivity of antibodies on necrotic thyroid tumors by examining a series of thyroid tumors ...

journal_title：Human pathology

authors： Judkins AR,Roberts SA,Livolsi VA

更新日期：1999-11-01 00:00:00

abstract：:Renomedullary interstitial cell tumors (RMICTs) are almost always incidentally identified either at autopsy or upon resection of the kidney for other reasons. However, rare cases that are large, resulting in a clinical mass, have been reported. The immunohistochemical phenotype of usual, incidental RMICT using modern ...

journal_title：Human pathology

authors： Lu Z,Al-Obaidy K,Cheng L,Perry KD,Grignon DJ,Williamson SR

更新日期：2018-12-01 00:00:00

abstract：:Morphological discrimination of urothelial carcinoma (UC) in situ, a precursor of high-grade invasive carcinoma, from severe reactive atypia is essential, but can be challenging at times. Mutations of the cell cycle regulatory gene INK4a (located at 9p21) that encodes p16(INK4) are one of the critical early events in ...

journal_title：Human pathology

authors： Yin M,Bastacky S,Parwani AV,McHale T,Dhir R

更新日期：2008-04-01 00:00:00

abstract：:Aberrant expression of the antiapoptotic protein BCL (B-cell lymphoma)-2 in neoplastic germinal centers is one of the diagnostic hallmarks of follicular lymphoma. If BCL-2 cannot be detected by immunohistochemistry, the distinction between florid follicular hyperplasia and follicular lymphoma might become a diagnostic...

journal_title：Human pathology

authors： Hoeller S,Bihl MP,Zihler D,Cogliatti S,Ponzoni M,Zettl A,Went P,Foerster A,Hirschmann P,Tzankov A,Dirnhofer S

更新日期：2012-03-01 00:00:00

abstract：:We introduce a novel hybrid telepathology system providing simultaneous transmission of both real-time microscopy and static imagery at a reasonable cost. It is capable of capturing static, true color images at resolution of 1,520 x 1,144 pixels and providing live transmission of real-time video images of the glass sl...

journal_title：Human pathology

authors： Zhou J,Hogarth MA,Walters RF,Green R,Nesbitt TS

更新日期：2000-07-01 00:00:00

abstract：:Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a B-cell neoplasm that is typically CD5 negative. We describe the clinicopathologic, immunophenotypic, and cytogenetic features of 14 cases of CD5+ MALT lymphoma. There were 9 men and 5 women (median age, 68 years; range, 34-87 y...

journal_title：Human pathology

authors： Jaso J,Chen L,Li S,Lin P,Chen W,Miranda RN,Konoplev S,Medeiros LJ,Yin CC

更新日期：2012-09-01 00:00:00

abstract：:We report here an exceptional pattern of atypical lentiginous melanocytic proliferation within an adenoma, leading to focal lamina propria infiltration and pulmonary metastasis, which was considered as primary colonic mucosal melanoma (MM) in a Caucasian patient. Such case illustrates the diagnosis criteria required t...

journal_title：Human pathology

authors： Furudoï A,Caumont C,Dutriaux C,Cappellen D,Goussot JF,Vergier B,Merlio C,Barberis C,Merlio JP,Gros A

更新日期：2016-02-01 00:00:00

abstract：:This study aims to develop a prediction model for spontaneous regression of cervical intraepithelial neoplasia grade 2 (CIN 2) lesions based on simple clinicopathological parameters. The study was conducted at Maastricht University Medical Center, the Netherlands. The prediction model was developed in a retrospective ...

journal_title：Human pathology

authors： Koeneman MM,van Lint FHM,van Kuijk SMJ,Smits LJM,Kooreman LFS,Kruitwagen RFPM,Kruse AJ

更新日期：2017-01-01 00:00:00

abstract：:A case of a tail in a 2-week-old infant is reported, and findings from a review of 33 previously reported cases of true tails and pseudotails are summarized. The true, or persistent, vestigial tail of humans arises from the most distal remnant of the embryonic tail. It contains adipose and connective tissue, central b...

journal_title：Human pathology

authors： Dao AH,Netsky MG

更新日期：1984-05-01 00:00:00

abstract：:Neoplasms consisting of pituitary adenoma and craniopharyngioma components are rare and are being increasingly recognized. Their histogenesis is not clear. Most represent collision tumors; others are difficult to assess. Here, we describe a pituitary adenoma with an intermingled craniopharyngioma component, without fo...

journal_title：Human pathology

authors： Gokden M,Mrak RE

更新日期：2009-08-01 00:00:00

abstract：:Bone marrow biopsy findings in 32 homosexual patients with the acquired immunodeficiency syndrome (AIDS) or prodromal AIDS are described. A high incidence (38 per cent) of nonparatrabecular lymphohistiocytic infiltrations containing irregular small lymphocytes was observed, as well as the presence of diffuse bone marr...

journal_title：Human pathology

authors： Osborne BM,Guarda LA,Butler JJ

更新日期：1984-11-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) promotes growth of blood or lymphatic vessels. The aim of the current study is to identify relationships between VEGF-A and VEGF-C, and their impact in angiogenesis and metastases in thyroid cancers. VEGF-A and VEGF-C mRNA and protein expression was investigated in 136 thyroid...

journal_title：Human pathology

authors： Salajegheh A,Pakneshan S,Rahman A,Dolan-Evans E,Zhang S,Kwong E,Gopalan V,Lo CY,Smith RA,Lam AK

更新日期：2013-10-01 00:00:00

abstract：:To ensure appropriate mission-based budgeting and equitable distribution of funds for faculty salaries, our compensation committee developed a pathology-specific effort reporting database. Principles included the following: (1) measurement should be done by web-based databases; (2) most entry should be done by departm...

journal_title：Human pathology

authors： Dee FR,Haugen TH,Wynn PA,Leaven TC,Kemp JD,Cohen MB

更新日期：2008-04-01 00:00:00

abstract：:Human papilloma virus (HPV) has emerged as the key etiologic driver in the majority of cancers at head and neck mucosal sites. First described in the uterine cervix and subsequently in oropharyngeal squamous cell carcinomas, the morphologic and clinical spectrum of HPV-related neoplasia has continued to expand and now...

journal_title：Human pathology

authors： Devins KM,Tetzlaff MT,Baloch Z,LiVolsi VA

更新日期：2019-12-01 00:00:00

abstract：:The Ewing family of tumors (EFT) is characterized by high MIC2/CD99 expression and specific EWS/ETS gene rearrangements, resulting in different chimeric transcripts. Further division into peripheral primitive neuroectodermal tumors and Ewing's sarcoma is still debated and, in the absence of distinct morphological para...

journal_title：Human pathology

authors： Amann G,Zoubek A,Salzer-Kuntschik M,Windhager R,Kovar H

更新日期：1999-09-01 00:00:00