Abstract:
:Neoplasms consisting of pituitary adenoma and craniopharyngioma components are rare and are being increasingly recognized. Their histogenesis is not clear. Most represent collision tumors; others are difficult to assess. Here, we describe a pituitary adenoma with an intermingled craniopharyngioma component, without forming 2 distinct mass lesions or histologic delineation. Areas that suggest a transition between the 2 components were also present. It was clinically a nonfunctioning adenoma, which was also negative for pituitary hormones by immunohistochemistry. Its histogenesis and implications are discussed with a review of the literature.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Gokden M,Mrak REdoi
10.1016/j.humpath.2009.02.007subject
Has Abstractpub_date
2009-08-01 00:00:00pages
1189-93issue
8eissn
0046-8177issn
1532-8392pii
S0046-8177(09)00064-1journal_volume
40pub_type
杂志文章相关文献
HUMAN PATHOLOGY文献大全abstract::Columnar cell lesions of the breast are a spectrum of lesions in the terminal duct lobular units, which include columnar cell change, columnar cell hyperplasia, and columnar cell change or columnar cell hyperplasia with atypia. The latter was designated by the World Health Organization as flat epithelial atypia. We st...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2009.12.003
更新日期:2010-06-01 00:00:00
abstract::Papillary carcinoma of the breast is a variant of predominantly intraductal carcinoma characterized by a papillary growth pattern with fibrovascular support. Loss of heterozygosity (LOH) was evaluated at multiple chromosomal loci (including loci reported to show frequent genetic alterations in breast cancer) to determ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(98)90422-1
更新日期:1998-10-01 00:00:00
abstract::Hydrophilic polymers are commonly applied as surface coatings on vascular devices and have been shown to dissociate during endovascular use, causing hydrophilic polymer embolism (HPE). Adverse effects related to this phenomenon have been recognized and reported. The prevalence of this complication is unknown. We condu...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2014.09.011
更新日期:2015-02-01 00:00:00
abstract::We describe a case of a complete hydatidiform mole with a coexistent embryo. A 19-year-old Hispanic woman presented with an intrauterine pregnancy at 7 weeks gestational age. An ultrasound evaluation at that time showed a gestational sac and fetal heart activity was observed. Four weeks later, subsequent ultrasound st...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(96)90406-2
更新日期:1996-07-01 00:00:00
abstract::The aim of the current study was to test whether the grade group assessed in the index tumor nodule predicts biochemical recurrence after surgery. The study cohort series included 144 consecutive patients treated by laparoscopic radical prostatectomy. The following parameters were evaluated in each case: type of radic...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2019.08.012
更新日期:2019-11-01 00:00:00
abstract::This report describes the biopsy findings in four of 30 patients treated with cadaver osteochondral shell allografts for osteoarthritis in the knee. This study demonstrates that graft cartilage cells can survive in excess of 25 months, and that host bone can completely replace graft bone by creeping substitution. An i...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(77)80093-2
更新日期:1977-11-01 00:00:00
abstract::A 3-year-old boy with congenital nemaline myopathy had generalized muscle weakness and hypotonia since birth. He developed cardiac symptoms at 2 years of age and died from congestive heart failure. At autopsy, the heart was markedly dilated, involving both ventricles. Rod bodies were recognized not only in skeletal mu...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(90)90078-j
更新日期:1990-01-01 00:00:00
abstract::Prostate-specific membrane antigen (PSMA), a type II transmembrane metallo-peptidase highly overexpressed in prostate cancer cells, has been studied as a targeting molecule in prostate cancer. Recently, PSMA has also been found to be expressed in the neovasculature of multiple nonprostatic solid tumors. Because of its...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2009.06.003
更新日期:2009-12-01 00:00:00
abstract::The objective of this study was to analyze the expression and clinical role of the RNA-binding molecule HuR in metastatic high-grade ovarian serous carcinoma (HGSC). HUR mRNA expression by reverse-transcription polymerase chain reaction was analyzed in 66 effusions from patients diagnosed with HGSC. Protein expression...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2015.09.027
更新日期:2016-02-01 00:00:00
abstract::Snail1 and ZEB1 are transcriptional repressors that drive tumor initiation and metastasis in animal models. Snail1 and ZEB1 are frequently coexpressed in tumor cell lines, suggesting that these factors may cooperate to promote tumor progression. However, coexpression of these transcriptional repressors in primary huma...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2010.11.004
更新日期:2011-08-01 00:00:00
abstract::We describe a patient with adenosquamous carcinoma of the prostate. His history suggests a common histogenesis of the glandular and squamous elements of the tumor. A 60-year-old white man had adenocarcinoma of the prostate diagnosed by biopsy and then underwent radical prostatectomy, which showed adenosquamous carcino...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(95)90125-6
更新日期:1995-01-01 00:00:00
abstract::The use of prosthetic implants for breast augmentation has become commonplace. Although implants do not increase the risk of conventional mammary carcinoma, they are rarely associated with anaplastic large cell lymphoma. We report 2 cases of breast implant capsule-associated squamous cell carcinoma with poor clinical ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2017.07.011
更新日期:2017-09-01 00:00:00
abstract::Pseudomyogenic hemangioendothelioma (PHE) is an uncommon neoplasm with propensity for local recurrence. The tumor mimics epithelioid hemangioendothelioma and epithelioid sarcoma, representing a possible diagnostic pitfall. We investigated the clinicopathological, immunohistochemical, and fluorescence in situ hybridiza...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2017.10.023
更新日期:2018-01-01 00:00:00
abstract::Arginase-1 has been demonstrated as a marker for hepatocellular carcinoma (HCC) with higher sensitivity and specificity than HepPar-1 and glypican-3. However, its sensitivity is diminished in moderately and poorly differentiated HCCs. In the current study, we evaluated the utility of AGXT1 as a diagnostic marker. Immu...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2018.05.025
更新日期:2018-10-01 00:00:00
abstract::Brain metastases (BMs) are common complications of adenocarcinomas (ADCs) of the lung and are associated with a poor prognosis. Although an increasing amount of data indicates that dysregulated activity of mammalian target of rapamycin (mTOR) can influence the metastatic potential of various tumors, the role of mTOR c...
journal_title:Human pathology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.humpath.2016.12.012
更新日期:2017-04-01 00:00:00
abstract::The histopathology of 72 paragangliomas originating in the head and neck region of 71 patients is presented. There were 45 carotid body, 13 vagal body, eight jugulotympanic, and three nasal paragangliomas. In addition, two arose in the larynx and one in the area of the aortic arch. Tumors occurred in four unrelated fa...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(79)80008-8
更新日期:1979-03-01 00:00:00
abstract::Intraductal carcinoma of the prostate (IDC-P) and high-grade prostatic intraepithelial neoplasia (HGPIN) are two distinct intraductal lesions; the former is usually associated with invasive carcinoma and has an aggressive course while the latter is considered a precancerous lesion. In addition, there are morphological...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2014.03.011
更新日期:2014-08-01 00:00:00
abstract::Most esophageal intraepithelial lymphocytes (IELs) express T-cell markers. Increased numbers of esophageal IELs have been shown in reflux esophagitis. The cytotoxic potential and activity of esophageal IELs have not as yet been examined. Our objectives were to determine whether esophageal IELs express the recently des...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(99)90114-4
更新日期:1999-04-01 00:00:00
abstract::Focal adhesion kinase (FAK) is one of the central signaling molecules found at focal adhesion sites, which are specific areas on the cell membrane where cells attach to extracellular matrix proteins. Focal adhesion kinase interacts with multiple signaling and adaptor molecules and effects several signaling pathways. O...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2005.09.024
更新日期:2006-01-01 00:00:00
abstract::Abnormalities of the cell cycle are present in all neoplasms. Cyclin E, which regulates the G1/S phase transition of the cell cycle, plays an important role in many different cancers. To further investigate the role of cyclin E in invasive breast ductal carcinomas in South African women, representative sections from 1...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2001.21141
更新日期:2001-01-01 00:00:00
abstract::A case of a tail in a 2-week-old infant is reported, and findings from a review of 33 previously reported cases of true tails and pseudotails are summarized. The true, or persistent, vestigial tail of humans arises from the most distal remnant of the embryonic tail. It contains adipose and connective tissue, central b...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80079-9
更新日期:1984-05-01 00:00:00
abstract::Total parenteral nutrition (TPN) therapy is a well-recognized cause of liver injury. The histologic changes attributed to TPN in the literature vary widely. In this study, we describe the histopathologic changes associated with TPN therapy and relate these changes to various clinical parameters. We conducted a retrosp...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2011.07.008
更新日期:2012-06-01 00:00:00
abstract::Monocytoid B-cell lymphoma (MBCL) is a newly recognized, morphologically and immunologically distinct, low-grade B-cell neoplasm that may exist as a pure morphologic entity or as a component of a composite lymphoma. To determine whether cytogenetic abnormalities exist in cases of MBCL, fresh tissue from four lymphoma ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(93)90188-m
更新日期:1993-10-01 00:00:00
abstract::The distinction between Spitz nevus and melanoma is currently possible, applying a set of definite histological criteria. However, in certain lesions deviating from the stereotypical morphology of classic Spitz nevi ("atypical Spitz tumors"), the differentiation between benign and malignant cases appears problematic b...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2006.02.001
更新日期:2006-07-01 00:00:00
abstract::We report 2 cases of a lesion that we term inverted papilloma of the lower female genital tract, occurring in the cervix and upper vagina of 60- and 50-year-old women, respectively. Microscopically, the features were similar to those of inverted transitional papilloma of the urinary bladder with interconnecting island...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2011.03.011
更新日期:2012-03-01 00:00:00
abstract::Bioassay of hormones has a small but important role in defining the physiologic status of selected patients in whom immunoassay results do not correlate with clinical signs and symptoms. This article reviews three sensitive bioassays for hormones, which are based on 1) stimulation of adenylate cyclase in membrane prep...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/s0046-8177(84)80050-7
更新日期:1984-02-01 00:00:00
abstract::Clinicopathological and cytogenetic studies were performed on specimens from 43 patients with CD30-positive anaplastic large cell lymphoma (ALCL). All patients were born and lived in a human T-cell lymphotropic virus (HTLV)-I endemic area. Twenty-one patients (48.8%) had serum anti-HTLV-I antibody suggesting the prese...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(95)90165-5
更新日期:1995-06-01 00:00:00
abstract::Alpha-methyl CoA racemase (AMACR), a new molecular marker for prostate cancer, has been recently reported to be one of the most highly expressed genes in papillary renal cell carcinomas (RCCs). We tested the diagnostic usefulness of AMACR antibody in a series of 110 renal tumors: 53 papillary RCCs (33 type 1, 20 type ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2006.01.012
更新日期:2006-06-01 00:00:00
abstract::Giant cell tumor of tendon sheath (GCTS) and pigmented villonodular synovitis (PVNS) are common synovial "tumors." Their immunohistochemical profile, however, has not been well characterized, and uncertainty exists regarding their histogenesis and relationship to fibroma of tendon sheath. In an effort to clarify these...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(95)90226-0
更新日期:1995-07-01 00:00:00
abstract::An increase in S100 protein-positive cells has been reported in inflammatory bowel diseases, mainly Crohn disease. These cells were interpreted as myeloid-derived dendritic cells, chiefly in follicular areas. We were prompted to assess the nature of these cells in interfollicular areas of inflamed colonic mucosa in ul...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2008.11.017
更新日期:2009-08-01 00:00:00