Safety and efficacy of loteprednol etabonate for treatment of papillae in contact lens-associated giant papillary conjunctivitis.

abstract：PURPOSE:The mechanisms involved in the reported beneficial effects of Calcium dobesilate monohydrate (CaD) for the treatment of diabetic retinopathy (DR) remain to be elucidated. The main aim of the present study is to examine whether CaD prevents early events in the pathogenesis of DR such as neurodegeneration and vas...

journal_title：Current eye research

authors： Solà-Adell C,Bogdanov P,Hernández C,Sampedro J,Valeri M,Garcia-Ramirez M,Pasquali C,Simó R

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:Unstable tear film characterized by shorting of tear break-up time (BUT) is associated with discomfort and dryness in contact lens wearers. The glycocalyx is thought to be crucial in maintaining the wettability and lubrication of the ocular surface. We evaluated the ocular surface glycocalyx in soft contact len...

journal_title：Current eye research

authors： Fukui M,Yamada M,Akune Y,Shigeyasu C,Tsubota K

更新日期：2016-01-01 00:00:00

abstract：:Samples of aqueous humor from rabbits and humans were examined for growth effects on subconfluent monolayer fibroblast cultures from ocular and extraocular tissues. At a concentration of 20% aqueous by medium volume, both homologous and heterologous aqueous stimulated DNA synthesis in fibroblasts from both species. Th...

journal_title：Current eye research

authors： Burke J,Foster S,Herschler J

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:To assess the incidence of cell proliferation and apoptosis in epiretinal membranes from eyes with proliferative vitreoretinopathy (PVR), proliferative diabetic retinopathy (PDR), and macular pucker (MP) and to further investigate the potential involvement of key executors of apoptosis. METHODS:Epiretinal memb...

journal_title：Current eye research

authors： Zhang X,Barile G,Chang S,Hays A,Pachydaki S,Schiff W,Sparrow J

更新日期：2005-05-01 00:00:00

abstract：PURPOSE:The aim of the present study was to calculate the diameter of the central retinal artery from results as obtained with non-invasive techniques in healthy young subjects. METHODS:Twenty-four healthy male subjects participated in this study. Total retinal blood flow was calculated from combined bi-directional la...

journal_title：Current eye research

authors： Dorner GT,Polska E,Garhöfer G,Zawinka C,Frank B,Schmetterer L

更新日期：2002-12-01 00:00:00

abstract：PURPOSE:To compare the long-term outcomes and recurrence rate of extensive versus limited subconjunctival pterygium excision with conjunctival autograft. METHODS:This retrospective study included 135 consecutive patients (161 eyes) who had pterygium excision with conjunctival autograft at the cornea performed at the c...

journal_title：Current eye research

authors： Bahar I,Kaiserman I,Weisbrod M,McAllum P,Slomovic A

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:Modern refractive surgery and follow up relies on a knowledge of corneal thickness (CT) and shape, and the reliability of modern instrumentation providing such data is important. This study sought to determine the performance of the TOPCON SP-2000P specular microscope in measuring CT. The aims of this study wer...

journal_title：Current eye research

authors： Cho P,Cheung SW

更新日期：2000-10-01 00:00:00

abstract：:Purpose/aim of the study: To observe and analyze the weekly changes in morphology and size of vacuoles, so called Wedl cells, in eyes with posterior subcapsular cataract (PSC). MATERIALS AND METHODS:Thirty-six eyes of 36 patients with pronounced PSC were included in this prospective study. High-resolution retroillumi...

journal_title：Current eye research

authors： Neumayer T,Hirnschall N,Georgopoulos M,Findl O

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To evaluate 24-hr intraocular pressure (IOP) and blood pressure (BP) with timolol or latanoprost/timolol fixed combination (LTFC). METHODS:Patients with primary open-angle glaucoma or ocular hypertension with normal blood pressure were randomized to LTFC, dosed each evening, or timolol dosed twice daily in a c...

journal_title：Current eye research

authors： Konstas AG,Pikilidou MI,Tsironi S,Mikropoulos D,Kozobolis VP,Sarafidis PA,Lasaridis AN,Nelson LA,Stewart WC

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:In the mature retina retinoic acid (RA) biosynthesis was reported to be regulated by light. RA is of vital importance for proper function of the retina. RA activity is mediated by interaction with nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs). The purpose of this study was to determine ...

journal_title：Current eye research

authors： Janssen JJ,Kuhlmann ED,van Vugt AH,Winkens HJ,Janssen BP,Deutman AF,Driessen CA

更新日期：1999-10-01 00:00:00

abstract：PURPOSE:Deficiency in Cystathionine β-synthase (CBS) leads to an abnormal accumulation of homocysteine and results in classical homocystinuria, a multi-systemic disorder that affects connective tissue, muscles, the central nervous system, and the eyes. However, the genetic players and mechanisms underlying vision alter...

journal_title：Current eye research

authors： Flores-Flores M,Moreno-García L,Castro-Martínez F,Nahmad M

更新日期：2020-09-07 00:00:00

abstract：:Hybridomas producing monoclonal antibodies to the retinal S antigen were obtained by fusion of spleen cells from a BALB/c mouse immunized with purified bovine S antigen and NS-1 myeloma cells. Six cloned hybridomas were selected and expanded as large scale cultures and as ascites in mice. The specificity of the antibo...

journal_title：Current eye research

authors： Faure JP,Mirshahi M,Dorey C,Thillaye B,de Kozak Y,Boucheix C

更新日期：1984-06-01 00:00:00

abstract：PURPOSE:Ethacrynic acid (ECA) has been shown to increase facility of aqueous outflow in whole eyes and perfused anterior segments, to open up spaces between cells in the trabecular meshwork and inner wall of Schlemm's canal, and to cause separation and retraction of trabecular meshwork and endothelial cells in culture....

journal_title：Current eye research

authors： O'Brien ET,Lee RE 3rd,Epstein DL

更新日期：1996-09-01 00:00:00

abstract：:The basement membrane of the crystalline lens of the diabetic rat was found to have a similar elasticity modulus at high stress to that of normal membrane. However, at low stress and extension Young's modulus of elasticity was 0.36 (Mean) +/- 0.15 (SD) X 10(6) Nm-2 and about 30 per cent lower than that of normal membr...

journal_title：Current eye research

authors： Hayes BP,Fisher RF

更新日期：1981-01-01 00:00:00

abstract：:Levels of rhodopsin in the photoreceptors of Long-Evans rats were reduced by approximately 55% through dietary deprivation of vitamin A. The interaction of visual pigment with G-protein was examined in receptor outer segment (ROS) membranes obtained from these animals. A binding assay was used to quantitate affinity o...

journal_title：Current eye research

authors： Pepperberg DR,Anderson SM,Crouch R

更新日期：1989-04-01 00:00:00

abstract：:Purpose: To investigate to what extent the OSDI can be utilized as a discriminative test for clinical findings. Methods: One thousand and ninety patients with dry eye disease (DED) were consecutively included and examined for osmolarity, tear film break-up time (TFBUT), ocular protection index (OPI), ocular surface st...

journal_title：Current eye research

authors： Yazdani M,Chen X,Tashbayev B,Utheim ØA,Ræder S,Hua Y,Eidet JR,Stojanovic A,Dartt DA,Utheim TP

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:The purpose of the current study is to assess changes in the expression of Acid-Sensing Ion Channel (ASIC)1a and ASIC2 in retinal ganglion cells (RGCs) after retinal ischemia and reperfusion (I/R) injury and to test if inhibition of ASIC1a provides RGC neuroprotection. METHODS:Transient ischemia was induced in...

journal_title：Current eye research

authors： Dibas A,Millar C,Al-Farra A,Yorio T

更新日期：2018-07-01 00:00:00

abstract：:The goal of this study was to determine the effect of extracellular matrix components on the phagocytic function of the retinal pigment epithelial (RPE) cell. Cultured human fetal RPE cells were established in culture and plated on three commercially-prepared substrates: collagen IV, fibronectin and laminin and on thr...

journal_title：Current eye research

authors： Miceli MV,Newsome DA

更新日期：1996-01-01 00:00:00

abstract：:A bovine lens "native" plasma membrane fraction containing its full compliment of extrinsic proteins was prepared by sucrose density centrifugation of the water insoluble fraction. The major membrane fraction was found at the 25/45% sucrose interface. This fraction contained 73% of the total water insoluble phospholip...

journal_title：Current eye research

authors： Fleschner CR,Cenedella RJ

更新日期：1992-08-01 00:00:00

abstract：PURPOSE:Nona-D-arginine amide (D9R) affected a cure of Pseudomonas aeruginosa corneal disease when combined with ciprofloxacin. In this study, we show that D9R alone and prophylactic treatment with D9R significantly reduced corneal pathology and bacterial burden associated with P. aeruginosa infection. MATERIALS AND M...

journal_title：Current eye research

authors： Karicherla P,Hobden JA

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to characterize swelling pressure-thickness, swelling pressure-hydration and hydration-thickness relations of porcine cornea. METHODS:Mechanical compression tests and free swelling experiments were performed on porcine cornea. A rheometer (DHR-2, TA Instruments) with a thermally contr...

journal_title：Current eye research

authors： Hatami-Marbini H,Etebu E,Rahimi A

更新日期：2013-11-01 00:00:00

abstract：:Achieving the long-term goal of successful engraftment of retinal tissues into eyes blinded by endogenous retinal failure will depend, at least in part, on controlling the immune response to antigens expressed on retinal grafts. Since histoincompatible tissues will have to be used for such transplants, methods to cont...

journal_title：Current eye research

authors： Jiang LQ,Streilein JW

更新日期：1992-07-01 00:00:00

abstract：PURPOSE:We located immunohistochemically the matrix metalloproteinases (MMP) -1, -2, -3 and -9 and the tissue inhibitors of matrix metalloproteinases (TIMP) -1 and -2 in the fibrous capsule of patients with intraocular lenses (IOLs). METHODS:During vitreoretinal surgery in 10 patients we obtained post-cataract surgery...

journal_title：Current eye research

authors： Kawashima Y,Saika S,Miyamoto T,Yamanaka O,Okada Y,Tanaka S,Ohnishi Y

更新日期：2000-12-01 00:00:00

abstract：AIM OF THE STUDY:The similarity of many benign intrabulbar lesions to a malignant tumor requires detailed differential diagnostics. However, none of the known methods can be used as the only one to determine the type of lesions. The aim of this study was to determine color Doppler imaging (CDI) markers characteristic o...

journal_title：Current eye research

authors： Modrzejewska M,Wiącek MP

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To determine the role of matrix metalloproteinase 9 (MMP9) in advanced glycation end-products (AGEs) induced damage to blood-retinal barrier (BRB) and the therapeutic effects of minocycline, an MMP inhibitor, against the BRB damages. METHODS:Forty-eight Sprague Dawley rats were randomly assigned to 3 groups (1...

journal_title：Current eye research

authors： Chen YD,Xu X,Xia X,Wu H,Liu K,Zheng Z,Zhu D

更新日期：2008-11-01 00:00:00

abstract：:Many tissues which require vitamin A store the vitamin as long-chain fatty acyl esters of retinol. As part of a study designed to characterize vitamin A metabolism in the lacrimal gland, which transports retinol from blood to lacrimal gland fluid, extracts from lacrimal glands of rabbits and rats were analyzed by non-...

journal_title：Current eye research

authors： Ubels JL,Osgood TB,Foley KM

更新日期：1988-10-01 00:00:00

abstract：:Human endothelial morphologic changes were quantitated by specular microscopy and computer-assisted morphometry to establish normal baselines of various morphologic parameters. Cellular polymegethism and cellular pleomorphism increases with age, and normal baseline parameters are detailed. Furthermore, no significant ...

journal_title：Current eye research

authors： Yee RW,Matsuda M,Schultz RO,Edelhauser HF

更新日期：1985-06-01 00:00:00

abstract：:In the Royal College of Surgeons rat, the migration of phagocytic cells into the subretinal space accompanies photoreceptor cell death during the early stages of retinal dystrophy. These are followed closely by cellular alterations in the retinal pigment epithelium, Müller cells, and outer retinal vessels. We have ide...

journal_title：Current eye research

authors： Roque RS,Caldwell RB

更新日期：1993-03-01 00:00:00

abstract：PURPOSE:The repair of the corneal epithelium is modulated by matrix metalloproteinases. The present study examined the effects of recombinant (r-) tissue inhibitors of metalloproteinases-1 and -2 (TIMP-1 and -2) on the proliferation of cultured epithelial cells from rabbit cornea, and on the spreading of a sheet of squ...

journal_title：Current eye research

authors： Saika S,Kawashima Y,Okada Y,Tanaka SI,Yamanaka O,Ohnishi Y,Ooshima A

更新日期：1998-01-01 00:00:00

abstract：:Calcium permeability was significantly increased in lenses from rats 36 h following a single injection of a cataractogenic dose of sodium selenite (30 nmol/g body weight) and this permeability returned to control values by 72 h post-injection (PI). The greater Ca2+ permeability could be partially reversed by incubatin...

journal_title：Current eye research

authors： Wang Z,Bunce GE,Hess JL

更新日期：1993-03-01 00:00:00