Increased plasma levels of brain natriuretic peptide in patients with acute myocardial infarction.

abstract：BACKGROUND:Proto-oncogenes have been implicated in the pathogenesis of gene-mediated myocardial remodeling. In the human heart, however, it has not been clarified whether these proto-oncogenes are related to contractile impairment and structural alteration of the myocardium. The present study is designed to investigate...

journal_title：Circulation

authors： Taketani S,Sawa Y,Taniguchi K,Mitsuno M,Kawaguchi N,Onishi S,Matsuda H

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:Thirteen of 14 epidemiological studies have shown an increased risk of approximately 20% for coronary heart disease (CHD) for never-smokers exposed to environmental tobacco smoke (ETS), but this association remains controversial. If true, ETS might account for an estimated 35,000 to 40,000 heart disease deat...

journal_title：Circulation

authors： Steenland K,Thun M,Lally C,Heath C Jr

更新日期：1996-08-15 00:00:00

abstract：:Heart potentials were recorded from the entire chest surface in 42 patients suffering from Wolff-Parkinson-White syndrome. We were able to identify six types of surface maps, according to the location of the potential maximum and minimum during the delta wave. For each of these types we suggested the most likely locat...

journal_title：Circulation

authors： De Ambroggi L,Taccardi B,Macchi E

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:Smooth muscle cell (SMC) migration and proliferation critically influence the clinical course of vascular disease. We tested the effect of the novel small leucine-rich repeat protein podocan on SMC migration and proliferation using a podocan-deficient mouse in combination with a model of arterial injury and ...

journal_title：Circulation

authors： Hutter R,Huang L,Speidl WS,Giannarelli C,Trubin P,Bauriedel G,Klotman ME,Fuster V,Badimon JJ,Klotman PE

更新日期：2013-11-26 00:00:00

abstract：:The outlook for patients with double-outlet right ventricle has improved since the development of corrective operations. Late arrhythmic deaths after successful procedures have been reported; however, the magnitude remains unknown. This study was undertaken to identify the magnitude of late sudden death and the signif...

journal_title：Circulation

authors： Shen WK,Holmes DR Jr,Porter CJ,McGoon DC,Ilstrup DM

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Children awaiting heart transplantation have severe limitations in their ability to exercise. The purpose of this study was to assess exercise capacity after pediatric heart transplantation and to identify factors influencing exercise performance. METHODS AND RESULTS:Progressive cycle ergometry testing was ...

journal_title：Circulation

authors： Hsu DT,Garofano RP,Douglas JM,Michler RE,Quaegebeur JM,Gersony WM,Addonizio LJ

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Transcatheter aortic valve replacement (TAVR) represents a paradigm shift in the therapeutic options for patients with severe aortic stenosis. However, rapid and exponential growth in TAVR demand may overwhelm capacity, translating to inadequate access and prolonged wait times. Our objective was to evaluate ...

journal_title：Circulation

authors： Elbaz-Greener G,Masih S,Fang J,Ko DT,Lauck SB,Webb JG,Nallamothu BK,Wijeysundera HC

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:Clinical detection of transplant rejection by repeated endomyocardial biopsy requires catheterization and entails risks. Recently developed molecular and cellular imaging techniques that visualize macrophage host responses could provide a noninvasive alternative. Yet, which macrophage functions may provide u...

journal_title：Circulation

authors： Christen T,Nahrendorf M,Wildgruber M,Swirski FK,Aikawa E,Waterman P,Shimizu K,Weissleder R,Libby P

更新日期：2009-04-14 00:00:00

abstract：BACKGROUND:Ticagrelor, when compared with clopidogrel, reduced the 12-month risk of vascular death/myocardial infarction and stroke in patients with ST-elevation acute coronary syndromes intended to undergo primary percutaneous coronary intervention in the PLATelet inhibition and patient Outcomes (PLATO) trial. This pr...

journal_title：Circulation

authors： Armstrong PW,Siha H,Fu Y,Westerhout CM,Steg PG,James SK,Storey RF,Horrow J,Katus H,Clemmensen P,Harrington RA,Wallentin L

更新日期：2012-01-24 00:00:00

abstract：BACKGROUND:Lead V(1) directly faces the right ventricle and may exhibit ST elevation during an acute inferior myocardial infarction when the right ventricle is also involved. Leads V(1) and V(3) indirectly face the posterolateral left ventricle, and ST depression ("mirror-image" ST elevation) in V(1) through V(3) may r...

journal_title：Circulation

authors： Wong CK,Gao W,Stewart RA,French JK,Aylward PE,Benatar J,White HD,Hirulog and Early Reperfusion or Occlusion-2 Investigators.

更新日期：2010-08-03 00:00:00

abstract：:We performed a 15 year follow-up of 748 patients undergoing bypass surgery, comparing 532 patients with one or two internal mammary artery grafts with or without additional saphenous vein grafts to 216 patients with saphenous vein grafts alone. During the 15 years of follow-up the 532 patients with at least one intern...

journal_title：Circulation

authors： Cameron A,Kemp HG Jr,Green GE

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:In patients with atrial fibrillation, intracardiac atrial defibrillation causes discomfort. An easily applicable, short-acting analgesic and anxiolytic drug would increase acceptability of this new treatment mode. METHODS AND RESULTS:In a double-blind, placebo-controlled manner, the effect of intranasal but...

journal_title：Circulation

authors： Timmermans C,Rodriguez LM,Ayers GM,Lambert H,Smeets JL,Vlaeyen JW,Albert A,Wellens HJ

更新日期：1999-04-13 00:00:00

abstract：BACKGROUND:The involvement of the complement system in brain injury has been scarcely investigated. Here, we document the pivotal role of mannose-binding lectin (MBL), one of the recognition molecules of the lectin complement pathway, in brain ischemic injury. METHODS AND RESULTS:Focal cerebral ischemia was induced in...

journal_title：Circulation

authors： Orsini F,Villa P,Parrella S,Zangari R,Zanier ER,Gesuete R,Stravalaci M,Fumagalli S,Ottria R,Reina JJ,Paladini A,Micotti E,Ribeiro-Viana R,Rojo J,Pavlov VI,Stahl GL,Bernardi A,Gobbi M,De Simoni MG

更新日期：2012-09-18 00:00:00

abstract：BACKGROUND:Magnetic resonance imaging (MRI) is an accurate method for the quantitative assessment of organic mitral regurgitation (OMR). The aim of the present study was to compare the discriminative power of MRI quantification and the recommended Doppler echocardiography (ECHO)-derived integrative approach to identify...

journal_title：Circulation

authors： Penicka M,Vecera J,Mirica DC,Kotrc M,Kockova R,Van Camp G

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:Depression is an independent risk factor for myocardial infarction (MI). Selective serotonin reuptake inhibitors (SSRIs) may reduce this risk through attenuation of serotonin-mediated platelet activation in addition to treatment of depression itself. METHODS AND RESULTS:case-control study of first MI in smo...

journal_title：Circulation

authors： Sauer WH,Berlin JA,Kimmel SE

更新日期：2001-10-16 00:00:00

abstract：BACKGROUND:Recent studies suggest that bone morphogenetic protein-2 (BMP-2), a transforming growth factor-beta superfamily member cytokine, plays an important role both in vascular development and pathophysiological processes, including endothelial activation that is likely to contribute to the development of coronary ...

journal_title：Circulation

authors： Csiszar A,Smith KE,Koller A,Kaley G,Edwards JG,Ungvari Z

更新日期：2005-05-10 00:00:00

abstract：:To determine the contribution of disopyramide's suggested opposing direct depressant and indirect acceleratory actions on sinus node function, we studied the effects of disopyramide, 1 x 10(-7) to 1 x 10(-4) M, on isolated rabbit sinus node preparations using standard microelectrode techniques. Transmembrane potential...

journal_title：Circulation

authors： Katoh T,Karagueuzian HS,Jordan J,Mandel WJ

更新日期：1982-12-01 00:00:00

abstract：:We performed transventricular pulmonary valvotomy as initial surgery in 22 consecutive patients with pulmonary atresia and intact ventricular septum who had a patent infundibulum. Nineteen patients also had placement of a central aortopulmonary shunt. All patients survived surgery, and 16 patients have had preoperativ...

journal_title：Circulation

authors： Shaddy RE,Sturtevant JE,Judd VE,McGough EC

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Adults with obesity or type 2 diabetes mellitus (T2DM) are at higher risk for stroke and myocardial infarction. Increased carotid intima-media thickness (cIMT) and stiffness are associated with these adverse outcomes. We compared carotid arteries in youth who were lean, were obese, or had T2DM. METHODS AND ...

journal_title：Circulation

authors： Urbina EM,Kimball TR,McCoy CE,Khoury PR,Daniels SR,Dolan LM

更新日期：2009-06-09 00:00:00

abstract：:Although the postoperative hemodynamic and echocardiographic features of idiopathic hypertrophic subaortic stenosis have been studied, the expected consistent postoperative thinning of the interventricular septum has not been reported. In this study, the short-term effects of septal myectomy were evaluated in 16 patie...

journal_title：Circulation

authors： Schapira JN,Stemple DR,Martin RP,Rakowski H,Stinson EB,Popp RL

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:The TAXUS NIRx stent (Boston Scientific Corp) provides local delivery of paclitaxel via a slow-release polymer coating. The TAXUS I trial was the first in-human experience evaluating safety and feasibility of the TAXUS NIRx stent system compared with bare NIR stents (control) (Boston Scientific Corp) for tre...

journal_title：Circulation

authors： Grube E,Silber S,Hauptmann KE,Mueller R,Buellesfeld L,Gerckens U,Russell ME

更新日期：2003-01-07 00:00:00

abstract：BACKGROUND:Prolonged survival of xenografted neonatal cardiomyocytes was achieved by blocking the CD28/B7 costimulatory pathway via CTLA4-Ig gene transfer. We examined the long-term survival of xenografted neonatal cardiomyocytes by adenovirus-mediated CTLA4-Ig expression and transient CD40 blockade with anti-CD40L mon...

journal_title：Circulation

authors： Li TS,Ito H,Kajiwara K,Hamano K

更新日期：2003-10-07 00:00:00

abstract：:Left main coronary artery disease (i.e., greater than or equal to 50% stenosis) was found in 1,477 of 20,137 patients in the Coronary Artery Surgery Study (CAS) registry. Of these patients, 53 (3.6%) were asymptomatic. Asymptomatic and symptomatic patients were similar in regard to 1) severity of left main coronary ar...

journal_title：Circulation

authors： Taylor HA,Deumite NJ,Chaitman BR,Davis KB,Killip T,Rogers WJ

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:The residual Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery (SYNTAX) Score is an objective measure of the degree and complexity of residual stenosis after percutaneous coronary intervention (PCI). METHODS AND RESULTS:In the randomized PCI cohort of the SYNTAX Trial (n=903)...

journal_title：Circulation

authors： Farooq V,Serruys PW,Bourantas CV,Zhang Y,Muramatsu T,Feldman T,Holmes DR,Mack M,Morice MC,Ståhle E,Colombo A,de Vries T,Morel MA,Dawkins KD,Kappetein AP,Mohr FW

更新日期：2013-07-09 00:00:00

abstract：BACKGROUND:Several individual pharmacological agents, such as antiplatelet drugs, beta-blockers, ACE inhibitors, and lipid-lowering agents, have proven efficacy in reducing mortality in patients with acute coronary syndromes. However, the impact of the combination of these agents on clinical outcomes has not been studi...

journal_title：Circulation

authors： Mukherjee D,Fang J,Chetcuti S,Moscucci M,Kline-Rogers E,Eagle KA

更新日期：2004-02-17 00:00:00

abstract：BACKGROUND:In patients with coronary artery disease (CAD), acute thrombosis frequently occurs in coronary arteries with only mild or moderate stenoses. Obesity increases the risk of atherosclerosis, but it is not known whether it also increases the risk of coronary thrombosis. We hypothesized that body mass index (BMI)...

journal_title：Circulation

authors： Wolk R,Berger P,Lennon RJ,Brilakis ES,Somers VK

更新日期：2003-11-04 00:00:00

abstract：BACKGROUND:Unlike the Western world, valvular disease ranks among the major cardiovascular afflictions in Africa. Acute rheumatic fever and chronic rheumatic valvular disease in their most virulent form are still commonly encountered and impose a huge burden on limited healthcare resources. METHODS AND RESULTS:We perf...

journal_title：Circulation

authors： Essop MR,Nkomo VT

更新日期：2005-12-06 00:00:00

abstract：BACKGROUND:Small-scale clinical investigations have demonstrated that single doses of beta-blocking agents can improve left ventricular function in heart failure from idiopathic dilated cardiomyopathy (IDC). The purpose of this multicenter clinical trial was to determine the dose-effect characteristics of beta-blockade...

journal_title：Circulation

authors： Bristow MR,O'Connell JB,Gilbert EM,French WJ,Leatherman G,Kantrowitz NE,Orie J,Smucker ML,Marshall G,Kelly P

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:We hypothesized that a simple, unmeasured posterior annuloplasty technique (two thirds of a 27-mm Duran ring) offered advantages of standardization and ease of insertion. METHODS AND RESULTS:A consecutive series of all patients (n = 418; median age, 67 years) having mitral valve repair performed by two surg...

journal_title：Circulation

authors： Odell JA,Schaff HV,Orszulak TA

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Sharing of patient-level clinical trial data has been widely endorsed. Little is known about how extensively these data have been used for cardiometabolic diseases. We sought to evaluate the availability and use of shared data from cardiometabolic clinical trials. METHODS:We extracted data from ClinicalStud...

journal_title：Circulation

authors： Vaduganathan M,Nagarur A,Qamar A,Patel RB,Navar AM,Peterson ED,Bhatt DL,Fonarow GC,Yancy CW,Butler J

更新日期：2018-02-27 00:00:00