Dynamic interaction between CD4+ T cells and parasitic helminths: mathematical models of heterogeneity in outcome.

abstract：:This study reports that inhibition of Leishmania Topo-I with the minor groove-binding ligands (MGBLs) Hoechst 33342 (Ho342) blocks parasite growth in culture by mechanisms involving DNA breakage. While Ho342 inhibited the replication of several species of Leishmania in a dose- and time-dependent manner, Ho258 was not ...

journal_title：Parasitology

authors： Marquis JF,Drolet M,Olivier M

更新日期：2003-01-01 00:00:00

abstract：:Ascarid parasites infect a variety of hosts and regular anthelmintic treatment is recommended for all species. Parascaris spp. is the only ascarid species with widespread anthelmintic resistance, which allows for the study of resistance mechanisms. The purpose of this study was to establish an in vitro drug exposure p...

journal_title：Parasitology

authors： Scare JA,Dini P,Norris JK,Steuer AE,Scoggin K,Gravatte HS,Howe DK,Slusarewicz P,Nielsen MK

更新日期：2020-05-01 00:00:00

abstract：:Oocysts of Cryptosporidium parvum showed relatively low levels of SOD activity. The SOD which had a pI of 4.8 and an approximate molecular weight of 35 kDa appeared to be iron dependent. Catalase, glutathione transferase, glutathione reductase and glutathione peroxidase activity could not be detected, nor could trypan...

journal_title：Parasitology

authors： Entrala E,Mascaro C,Barrett J

更新日期：1997-01-01 00:00:00

abstract：:Planning of the control of Plasmodium falciparum malaria leads to a need for models of malaria epidemiology that provide realistic quantitative prediction of likely epidemiological outcomes of a wide range of control strategies. Predictions of the effects of control often ignore medium- and long-term dynamics. The com...

journal_title：Parasitology

authors： Smith T,Maire N,Ross A,Penny M,Chitnis N,Schapira A,Studer A,Genton B,Lengeler C,Tediosi F,de Savigny D,Tanner M

更新日期：2008-11-01 00:00:00

abstract：:Highly purified mitochondrial fractions have been isolated from the intraerythrocytic stages of two mammalian Plasmodium spp., Plasmodium yoelii of rodents and Plasmodium falciparum of man. Mitochondria of the former parasite are cristate whereas those of the latter are essentially acristate. Isolated mitochondria fro...

journal_title：Parasitology

authors： Fry M,Beesley JE

更新日期：1991-02-01 00:00:00

abstract：:We have studied the genomic organization and transcription of the histone H2A genes in the protozoan parasite Leishmania infantum. In the parasite genome 2 gene clusters exist, each containing 3 H2A gene copies. Sequence analyses showed the existence of significant sequence divergence among the H2A genes, mainly in th...

journal_title：Parasitology

authors： Soto M,Quijada L,Larreta R,Iborra S,Alonso C,Requena JM

更新日期：2003-08-01 00:00:00

abstract：:Toxocariasis is a common helminthic infection that has a worldwide distribution. However, data from Lebanon about the prevalence of this infection are non-existent. We conducted a Toxocara seroprevalence study with 150 subjects attending the outpatient clinics at the American University of Beirut Medical Center betwee...

journal_title：Parasitology

authors： Kanafani ZA,Skoury A,Araj GF,El-Khoury M,Sawaya RA,Atweh SF,Kanj SS

更新日期：2006-05-01 00:00:00

abstract：:Monoclonal antibodies reacting with pellicular antigens of Toxoplasma gondii tachyzoites have been selected among hybridomas produced against this organism by immunofluorescence assay. These antigens have been further characterized by immunofluorescence on living zoites, Western immunoblotting and immunoprecipitation ...

journal_title：Parasitology

authors： Couvreur G,Sadak A,Fortier B,Dubremetz JF

更新日期：1988-08-01 00:00:00

abstract：:The tegumental surface of Schistosoma mansoni sporocysts is the site of both nutritive and immunological interactions with haemolymph cells and plasma of Biomphalaria glabrata, the schistosome intermediate host. Within minutes of being placed in host plasma, sporocysts acquire plasma antigens, and within 3 h host plas...

journal_title：Parasitology

authors： Bayne CJ,Loker ES,Yui MA

更新日期：1986-06-01 00:00:00

abstract：:We studied the monogenean communities of 34 species of butterflyfish from the tropical Indo-West Pacific, identifying 13 dactylogyrid species (including two species that are presently undescribed). Monogenean assemblages differed significantly between host species in terms of taxonomic structure, intensity and prevale...

journal_title：Parasitology

authors： Reverter M,Cutmore SC,Bray R,Cribb TH,Sasal P

更新日期：2016-10-01 00:00:00

abstract：:The anthelmintic properties of tanniferous plants and of their secondary metabolites represent one possible alternative to chemotherapy that is currently being explored as a means of achieving sustainable control of gastrointestinal nematodes in ruminants. Previous in vivo and in vitro results suggest that tanniferous...

journal_title：Parasitology

authors： Bahuaud D,Martinez-Ortiz de Montellano C,Chauveau S,Prevot F,Torres-Acosta F,Fouraste I,Hoste H

更新日期：2006-04-01 00:00:00

abstract：:Avian malaria is a vector transmitted disease caused by Plasmodium and recent studies suggest that variation in its prevalence across avian hosts is correlated with a variety of ecological traits. Here we examine the relationship between prevalence and diversity of Plasmodium lineages in southeastern Amazonia and: (1)...

journal_title：Parasitology

authors： Fecchio A,Ellis VA,Bell JA,Andretti CB,D'Horta FM,Silva AM,Tkach VV,Weckstein JD

更新日期：2017-07-01 00:00:00

abstract：:Leishmania are obligatory intracellular parasitic protozoa that cycle between sand fly mid-gut and phagolysosomes of mammalian macrophages. They have developed genetically programmed changes in gene and protein expression that enable rapid optimization of cell function according to vector and host environments. During...

journal_title：Parasitology

authors： Tsigankov P,Gherardini PF,Helmer-Citterich M,Zilberstein D

更新日期：2012-08-01 00:00:00

abstract：:Pentastomids comprise a highly specialized taxon of arthropod-like parasites that probably became adapted to the lungs of amphibians and reptiles early in their long evolutionary history. Few other macroparasites exploit this particular niche. Pentastomids are often large, long-lived and yet they cause little observab...

journal_title：Parasitology

authors： Riley J,Henderson RJ

更新日期：1999-01-01 00:00:00

abstract：:The mechanism by which Giardia lamblia exerts its pathogenicity is likely to be multifactorial. A 58 kDa enterotoxin was purified and characterized from the excretory-secretory product (ESP) of the parasite (Kaur et al. 2001). In the present study an attempt has been made to elucidate the mechanism of action of the ES...

journal_title：Parasitology

authors： Shant J,Ghosh S,Bhattacharyya S,Ganguly NK,Majumdar S

更新日期：2004-10-01 00:00:00

abstract：:Essential oils (EOs) are considered a new class of ecological products aimed at the control of insects for industrial and domestic use; however, there still is a lack of studies involving the control of fleas. Ctenocephalides felis felis, the most observed parasite in dogs and cats, is associated with several diseases...

journal_title：Parasitology

authors： Dos Santos JVB,de Almeida Chaves DS,de Souza MAA,Riger CJ,Lambert MM,Campos DR,Moreira LO,Dos Santos Siqueira RC,de Paulo Osorio R,Boylan F,Correia TR,Coumendouros K,Cid YP

更新日期：2020-03-01 00:00:00

abstract：:Polychromophilus murinus, a malaria parasite of Chiroptera is reported from Myotis daubentoni in England. The vector was suspected to be the ectoparasitic Nycteribiid fly, Nycteribia kolenatii. N. kolenatii collected from wild-caught M. daubentoni were found to have oocysts on the midgut and sporozoites in the salivar...

journal_title：Parasitology

authors： Gardner RA,Molyneux DH

更新日期：1988-06-01 00:00:00

abstract：:Adult Onchocerca volvulus worms obtained by enzyme digestion from nodules of infected Mexicans were radio-isotope labelled by the chloramine-T or Bolton-Hunter methods. No antigenic determinants were detected in extracts of worms labelled by the chloramine-T method but 3 antigens were detected in extracts of the Bolto...

journal_title：Parasitology

authors： Philipp M,Gómez-Priego A,Parkhouse RM,Davies MW,Clark NW,Ogilvie BM,Beltrán-Hernández F

更新日期：1984-10-01 00:00:00

abstract：:Engorged Ixodes ricinus nymphs collected from sheep resident in an upland UK field site were significantly lighter than nymphs that engorged on previously tick-naïve sheep, indicating that site-resident sheep continually exposed to ticks acquired anti-tick resistance. The weights of engorged nymphs that fed on natural...

journal_title：Parasitology

authors： Ogden NH,Casey AN,French NP,Adams JD,Woldehiwet Z

更新日期：2002-02-01 00:00:00

abstract：:Intestinal diarrheagenic polyparasitic infections are among the major public health concerns in developing countries. Here we examined stool specimens by microscopy, DNA dot blot and polymerase chain reaction (PCR) to evaluate the co-infection of four principal protozoans among amoebic dysentery cases from Northeast I...

journal_title：Parasitology

authors： Nath J,Hussain G,Singha B,Paul J,Ghosh SK

更新日期：2015-09-01 00:00:00

abstract：:Anti-trypanosomiasis vaccination still remains the best theoretical option in the fight against a disease that is continuously hovering between its wildlife reservoir and its reservoir in man and livestock. While antigenic variation of the parasite surface coat has been considered the major obstacle in the development...

journal_title：Parasitology

authors： Magez S,Caljon G,Tran T,Stijlemans B,Radwanska M

更新日期：2010-12-01 00:00:00

abstract：:Intraerythrocytic malaria parasites ingest the cytosol of their host cell and digest it inside their acid food vacuoles. Acidified (pH 4-5.5, 37 degrees C) human red blood cell lysates were used to simulate this process, measuring the denaturation of haemoglobin (Hb) and the release of iron, in the absence or presence...

journal_title：Parasitology

authors： Gabay T,Krugliak M,Shalmiev G,Ginsburg H

更新日期：1994-05-01 00:00:00

abstract：:The effect of different incubation media and of temperature on the induction of water sensitivity has been investigated in intact and tailless Schistosoma mansoni cercariae. Removal of the cercarial tail by vortex stirring and elevation of the temperature of the medium from 27 to 37 degrees C resulted in the rapid ons...

journal_title：Parasitology

authors： Ramalho-Pinto FJ,Gazzinelli G,Howells RE,Pellegrino J

更新日期：1975-08-01 00:00:00

abstract：:The glycolytic enzyme triosephosphate isomerase catalyses the isomerization between glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Here we report that Trichomonas vaginalis contains 2 fully functional tpi genes. Both genes are located in separated chromosomal context with different promoter regulatory elem...

journal_title：Parasitology

authors： Figueroa-Angulo EE,Estrella-Hernández P,Salgado-Lugo H,Ochoa-Leyva A,Gómez Puyou A,Campos SS,Montero-Moran G,Ortega-López J,Saab-Rincón G,Arroyo R,Benítez-Cardoza CG,Brieba LG

更新日期：2012-11-01 00:00:00

abstract：:Hybridization events between Schistosoma species (Digenea, Platyhelminthes) are reported with increasing frequency, largely due to improved access to molecular tools. Nevertheless, little is known about the distribution and frequency of hybrid schistosomes in nature. Screening for hybrids on a large scale is complicat...

journal_title：Parasitology

authors： Boon NAM,Van Den Broeck F,Faye D,Volckaert FAM,Mboup S,Polman K,Huyse T

更新日期：2018-04-01 00:00:00

abstract：:Judged by oocyst production, infections with Eimeria acervulina in birds immunized with E. maxima were consistently higher than in birds which had not been immunized. Oocyst production of E. maxima in birds previously infected with E. acervulina was greater, in three out of four experiments, than in control chickens,...

journal_title：Parasitology

authors： Rose ME

更新日期：1975-04-01 00:00:00

abstract：:Epidemiological rate parameters of host generalist parasites are difficult to estimate, especially in cases where variation in parasite performance can be attributed to host species. Such cases are likely common for generalist parasites of sympatric grazing mammals. In this study, we combined data from experimental ex...

journal_title：Parasitology

authors： Beck MA,Goater CP,Colwell DD

更新日期：2015-09-01 00:00:00

abstract：:Thirty-one stocks of Trypanosoma cruzi, the agent of Chagas disease, representative of the genetic variability of the 2 principal lineages, that subdivide T. cruzi, were selected on the basis of previous multilocus enzyme electrophoresis analysis using 21 loci. Analyses were performed with lower numbers of loci to exp...

journal_title：Parasitology

authors： Breniere SF,Barnabe C,Bosseno MF,Tibayrenc M

更新日期：2003-09-01 00:00:00

abstract：:A time-course study was conducted to resolve discrepancies in the literature and better define aspects of the Eimeria maxima life cycle such, as sites of development and both morphology and number of asexual stages. Broiler chickens were inoculated orally with five million E. maxima oocysts (APU1), and were necropsied...

journal_title：Parasitology

authors： Dubey JP,Jenkins MC

更新日期：2018-07-01 00:00:00

abstract：:Serology is an important tool for the diagnosis of alveolar echinococcosis (AE) in humans. In order to improve serodiagnostic performance, we have developed an in vitro-produced Echinococcus mulilocularis metacestode vesicle fluid (EmVF) antigen for application in an immunoblot assay. Immunoblot analysis of EmVF revea...

journal_title：Parasitology

authors： Müller N,Frei E,Nuñez S,Gottstein B

更新日期：2007-06-01 00:00:00