Abstract:
:Essential oils (EOs) are considered a new class of ecological products aimed at the control of insects for industrial and domestic use; however, there still is a lack of studies involving the control of fleas. Ctenocephalides felis felis, the most observed parasite in dogs and cats, is associated with several diseases. The aim of this study was to evaluate the in vitro activity, the establishment of LC50 and toxicity of EOs from Alpinia zerumbet (Pers.) B. L. Burtt & R. M. Sm, Cinnamomum spp., Laurus nobilis L., Mentha spicata L., Ocimum gratissimum L. and Cymbopogon nardus (L.) Rendle against immature stages and adults of C. felis felis. Bioassay results suggest that the method of evaluation was able to perform a pre-screening of the activity of several EOs, including the discriminatory evaluation of flea stages by their LC50. Ocimum gratissimum EO was the most effective in the in vitro assays against all flea stages, presenting adulticide (LC50 = 5.85 μg cm-2), ovicidal (LC50 = 1.79 μg cm-2) and larvicidal (LC50 = 1.21 μg cm-2) mortality at low doses. It also presented an excellent profile in a toxicological eukaryotic model. These findings may support studies involving the development of non-toxic products for the control of fleas in dogs and cats.
journal_name
Parasitologyjournal_title
Parasitologyauthors
Dos Santos JVB,de Almeida Chaves DS,de Souza MAA,Riger CJ,Lambert MM,Campos DR,Moreira LO,Dos Santos Siqueira RC,de Paulo Osorio R,Boylan F,Correia TR,Coumendouros K,Cid YPdoi
10.1017/S0031182019001641subject
Has Abstractpub_date
2020-03-01 00:00:00pages
340-347issue
3eissn
0031-1820issn
1469-8161pii
S0031182019001641journal_volume
147pub_type
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