Cross-neutralization of human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus isolates.

abstract：:The gD, gB, and gH/gL glycoprotein quartet constitutes the basic apparatus for herpes simplex virus (HSV) entry into the cell and fusion. gD serves as a receptor binding glycoprotein and trigger of fusion. The conserved gB and gH/gL execute fusion. Central to understanding HSV entry/fusion has become the dissection of...

journal_title：Journal of virology

authors： Avitabile E,Forghieri C,Campadelli-Fiume G

更新日期：2009-10-01 00:00:00

abstract：:Effective, vaccine-induced CD8+ T-cell responses should recognize infected cells early enough to prevent production of progeny virions. We have recently shown that Gag-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells at 2 h postinfection, whereas Env-specific CD8+ T cells do not recognize i...

journal_title：Journal of virology

authors： Sacha JB,Chung C,Reed J,Jonas AK,Bean AT,Spencer SP,Lee W,Vojnov L,Rudersdorf R,Friedrich TC,Wilson NA,Lifson JD,Watkins DI

更新日期：2007-11-01 00:00:00

abstract：:Extrachromosomal DNA was isolated from tissue culture cells that were acutely infected with simian sarcoma virus (SSV) and its associated helper (simian sarcoma-associated virus [SSAV]). Two sizes of closed circular viral genomic DNA intermediates were isolated, cleaved at the single EcoRI site, and ligated to the Cha...

journal_title：Journal of virology

authors： Gelmann EP,Petri E,Cetta A,Wong-Staal F

更新日期：1982-02-01 00:00:00

abstract：:We have previously demonstrated that the human papillomavirus (HPV) genome replicates effectively in U2OS cells after transfection using electroporation. The transient extrachromosomal replication, stable maintenance, and late amplification of the viral genome could be studied for high- and low-risk mucosal and cutane...

journal_title：Journal of virology

authors： Reinson T,Toots M,Kadaja M,Pipitch R,Allik M,Ustav E,Ustav M

更新日期：2013-01-01 00:00:00

abstract：:The human immunodeficiency virus (HIV) and the closely related simian immunodeficiency virus (SIV) induce profound immune dysfunction in primate species. The present studies show that cell populations infected in vitro with SIV exhibit increases in major histocompatibility complex (MHC) class II antigen expression. Ce...

journal_title：Journal of virology

authors： Kannagi M,Kiyotaki M,King NW,Lord CI,Letvin NL

更新日期：1987-05-01 00:00:00

abstract：:Recently, efficient and long-term in vivo gene transfer by recombinant adeno-associated virus type 2 (rAAV) vectors has been demonstrated in a variety of tissues. Further improvement in vector titer and purity will expedite this in vivo exploration and provide preclinical information required for use in human gene the...

journal_title：Journal of virology

authors： Xiao X,Li J,Samulski RJ

更新日期：1998-03-01 00:00:00

abstract：:A herpes simplex virus type 1 (HSV-1) strain, B3, was found to have a short duplication on the left junction between the unique sequence (US) and the inverted repeat sequence (RS) in the S component of the genome DNA. A short region of RS contiguous to the left US-RS junction was duplicated in B3. Based on the nucleot...

journal_title：Journal of virology

authors： Umene K

更新日期：1989-05-01 00:00:00

abstract：:Recruitment and extravasation of T cells through the blood-brain barrier are favored by adhesion molecule-mediated interactions of circulating T cells with endothelial cells. Since a common pathological finding in human T-cell leukemia virus type 1 (HTLV-1)-associated diseases is the infiltration of HTLV-1-infected T ...

journal_title：Journal of virology

authors： Valentin H,Lemasson I,Hamaia S,Cassé H,König S,Devaux C,Gazzolo L

更新日期：1997-11-01 00:00:00

abstract：UNLABELLED:The cytosolic RIG-I (retinoic acid-inducible gene I) receptor plays a pivotal role in the initiation of the immune response against RNA virus infection by recognizing short 5'-triphosphate (5'ppp)-containing viral RNA and activating the host antiviral innate response. In the present study, we generated novel...

journal_title：Journal of virology

authors： Chiang C,Beljanski V,Yin K,Olagnier D,Ben Yebdri F,Steel C,Goulet ML,DeFilippis VR,Streblow DN,Haddad EK,Trautmann L,Ross T,Lin R,Hiscott J

更新日期：2015-08-01 00:00:00

abstract：:Arenaviruses are rodent-borne viruses, with five members of the family capable of causing severe hemorrhagic fevers if transmitted to humans. To date, two distinct cellular receptors have been identified that are used by different pathogenic viruses, alpha-dystroglycan by Lassa fever virus and transferrin receptor 1 (...

journal_title：Journal of virology

authors： Flanagan ML,Oldenburg J,Reignier T,Holt N,Hamilton GA,Martin VK,Cannon PM

更新日期：2008-01-01 00:00:00

abstract：:Unintegrated linear and closed circular DNAs of B- and N-tropic endogenous BALB/c murine leukemia virus (MuLV) were extracted from newly infected mouse cells and cleaved with EcoRI, XhoI, PvuI, HindIII, SalI, XbaI, KpnI, SmaI, and PstI restriction endonucleases. The DNA fragments were separated by electrophoresis and ...

journal_title：Journal of virology

authors： Rassart E,Jolicoeur P

更新日期：1980-09-01 00:00:00

abstract：:Aluminum (Al)-based salts are widely used adjuvants in ruminants and other species to strengthen the immune response elicited against vaccine antigen(s). However, they can lead to the formation of long-lasting granulomas composed of abundant activated macrophages. Small ruminant lentiviruses (SRLV) are widely distribu...

journal_title：Journal of virology

authors： Echeverría I,de Miguel R,Asín J,Rodríguez-Largo A,Fernández A,Pérez M,de Andrés D,Luján L,Reina R

更新日期：2020-12-22 00:00:00

abstract：:Three molecules have been identified as the main cellular factors required for binding and entry of human T-cell leukemia virus type 1 (HTLV-1): glucose transporter 1 (GLUT1), heparan sulfate (HS), and neuropilin 1 (NRP-1). However, the precise mechanism of HTLV-1 cell tropism has yet to be elucidated. Here, we examin...

journal_title：Journal of virology

authors： Tanaka A,Jinno-Oue A,Shimizu N,Hoque A,Mori T,Islam S,Nakatani Y,Shinagawa M,Hoshino H

更新日期：2012-03-01 00:00:00

abstract：:The spindles of Anomala cuprea entomopoxvirus (AncuEPV), which are composed of glycoprotein fusolin, are known to enhance the peroral infectivity of AncuEPV itself and of nucleopolyhedroviruses. This has been demonstrated to involve the disruption of intestinal peritrophic membrane (PM), composed of chitin matrix, gly...

journal_title：Journal of virology

authors： Takemoto Y,Mitsuhashi W,Murakami R,Konishi H,Miyamoto K

更新日期：2008-12-01 00:00:00

abstract：UNLABELLED:The immunoglobulin superfamily protein receptors for poliovirus, human rhinovirus, and coxsackievirus B (CVB) serve to bind the viruses to target cells and to facilitate the release of the virus genome by catalyzing the transition from the mature infectious virus to the A-particle uncoating intermediate. Rec...

journal_title：Journal of virology

authors： Carson SD

更新日期：2014-10-01 00:00:00

abstract：:Expression of mouse mammary tumor virus (MMTV)-encoded superantigens in B lymphocytes is required for viral transmission and pathogenesis. We have previously established a critical role of an enhancer element within the long terminal repeat (LTR) for MMTV sag gene expression in B-lymphoid progenitor cells. We now demo...

journal_title：Journal of virology

authors： Reuss FU,Coffin JM

更新日期：2000-09-01 00:00:00

abstract：:The localization of the adenovirus type 5 34-kDa E4 and 55-kDa E1B proteins was determined in the absence of other adenovirus proteins. When expressed by transfection in human, monkey, hamster, rat, and mouse cell lines, the E1B protein was predominantly cytoplasmic and typically was excluded from the nucleus. When ex...

journal_title：Journal of virology

authors： Goodrum FD,Shenk T,Ornelles DA

更新日期：1996-09-01 00:00:00

abstract：:Bank vole is a rodent species that shows differential susceptibility to the experimental transmission of different prion strains. In this work, the transmission features of a panel of diverse prions with distinct origins were assayed both in bank vole expressing methionine at codon 109 (Bv109M) and in transgenic mice ...

journal_title：Journal of virology

authors： Espinosa JC,Nonno R,Di Bari M,Aguilar-Calvo P,Pirisinu L,Fernández-Borges N,Vanni I,Vaccari G,Marín-Moreno A,Frassanito P,Lorenzo P,Agrimi U,Torres JM

更新日期：2016-11-14 00:00:00

abstract：:The prevalence and importance of microRNAs (miRNAs) in viral infection are increasingly relevant. Eleven miRNAs were previously identified in human cytomegalovirus (HCMV); however, miRNA content in murine CMV (MCMV), which serves as an important in vivo model for CMV infection, has not previously been examined. We hav...

journal_title：Journal of virology

authors： Buck AH,Santoyo-Lopez J,Robertson KA,Kumar DS,Reczko M,Ghazal P

更新日期：2007-12-01 00:00:00

abstract：:The replication of porcine circovirus type 1 (PCV1) is thought to occur by rolling-circle replication (RCR), whereby the introduction of a single-strand break generates a free 3'-hydroxyl group serving as a primer for subsequent DNA synthesis. The covalently closed, single-stranded genome of PCV1 replicates via a doub...

journal_title：Journal of virology

authors： Steinfeldt T,Finsterbusch T,Mankertz A

更新日期：2006-07-01 00:00:00

abstract：:Lipid rafts are proposed to function as platforms for both receptor signaling and trafficking. Following interaction with antigenic peptides, the T-cell receptor (TCR) rapidly translocates to lipid rafts, where it transmits signals and subsequently undergoes endocytosis. The Tip protein of herpesvirus saimiri (HVS), w...

journal_title：Journal of virology

authors： Park J,Cho NH,Choi JK,Feng P,Choe J,Jung JU

更新日期：2003-08-01 00:00:00

abstract：:The synthesis of minus-strand RNA was studied in cell cultures infected with the heat-resistant strain of Sindbis virus and with temperature-sensitive (ts) belonging to complementation groups A, B, F, and G, all of which exhibited an RNA-negative (RNA-) phenotype when infection was initiated and maintained at 39 degre...

journal_title：Journal of virology

authors： Sawicki DL,Sawicki SG,Keränen S,Kääriäinen L

更新日期：1981-08-01 00:00:00

abstract：:We have examined the pathway of rhinovirus interaction with soluble intercellular adhesion molecule 1 (sICAM-1). Binding of sICAM-1 to rhinovirus serotypes 3 and 14 gives particles with sedimentation coefficients from 145 to 120S, depending on the amount of sICAM-1 bound. The formation of 120S particles is faster and ...

journal_title：Journal of virology

authors： Casasnovas JM,Springer TA

更新日期：1994-09-01 00:00:00

abstract：UNLABELLED:Noroviruses are the leading cause of acute gastroenteritis outbreaks worldwide. The majority of norovirus outbreaks are caused by genogroup II.4 (GII.4). Novel GII.4 strains emerge every 2 to 4 years and replace older variants as the dominant norovirus. Novel variants emerge through a combination of recombin...

journal_title：Journal of virology

authors： Vega E,Donaldson E,Huynh J,Barclay L,Lopman B,Baric R,Chen LF,Vinjé J

更新日期：2014-12-01 00:00:00

abstract：:Prophylactic hepatitis C virus (HCV) vaccine trials with human volunteers are pending. There is an important need for immunological end points which correlate with vaccine efficacy and which do not involve invasive procedures, such as liver biopsies. By using a multicomponent DNA priming-protein boosting vaccine strat...

journal_title：Journal of virology

authors： Rollier C,Depla E,Drexhage JA,Verschoor EJ,Verstrepen BE,Fatmi A,Brinster C,Fournillier A,Whelan JA,Whelan M,Jacobs D,Maertens G,Inchauspé G,Heeney JL

更新日期：2004-01-01 00:00:00

abstract：UNLABELLED:HIV-1 Vpu decreases the exposure of epitopes within the viral envelope glycoprotein (Env) on the surface of infected cells by downregulating both BST2 and CD4. To test the hypothesis that inhibiting Vpu activity would increase the exposure of these epitopes and sensitize infected cells to antibody-dependent ...

journal_title：Journal of virology

authors： Tokarev A,Stoneham C,Lewinski MK,Mukim A,Deshmukh S,Vollbrecht T,Spina CA,Guatelli J

更新日期：2015-12-16 00:00:00

abstract：:China is facing a rapid upsurge in cases of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) infection due to large numbers of paid blood donors (PBD), injection drug users (IDU), and sexual partners of infected individuals. In this report, a total of 236 HIV-1-positive blood samples were collec...

journal_title：Journal of virology

authors： Zhang L,Chen Z,Cao Y,Yu J,Li G,Yu W,Yin N,Mei S,Li L,Balfe P,He T,Ba L,Zhang F,Lin HH,Yuen MF,Lai CL,Ho DD

更新日期：2004-12-01 00:00:00

abstract：:A variant of human T-cell leukemia virus subgroup I (HTLV-I), designated HTLV-Ib, has been isolated from a transformed T-lymphocytic cell line established from a Zairian patient with adult T-cell lymphoma. A recombinant phage clone of the variant provirus, denoted lambda MC-1, hybridizes under high stringency to HTLV-...

journal_title：Journal of virology

authors： Ratner L,Josephs SF,Starcich B,Hahn B,Shaw GM,Gallo RC,Wong-Staal F

更新日期：1985-06-01 00:00:00

abstract：:The contributions of the glycoproteins gI (ORF67) and gE (ORF68) to varicella-zoster virus (VZV) replication were investigated in deletion mutants made by using cosmids with VZV DNA derived from the Oka strain. Deletion of both gI and gE prevented virus replication. Complete deletion of gI or deletions of 60% of the N...

journal_title：Journal of virology

authors： Mallory S,Sommer M,Arvin AM

更新日期：1997-11-01 00:00:00

abstract：:It has been previously shown that rotavirus maturation and stability of the outer capsid are calcium-dependent processes. More recently, it has been hypothesized that penetration of the cell membrane is also affected by conformational changes of the capsid induced by Ca2+. In this study, we determined quantitatively t...

journal_title：Journal of virology

authors： Ruiz MC,Charpilienne A,Liprandi F,Gajardo R,Michelangeli F,Cohen J

更新日期：1996-08-01 00:00:00